Resonance of cortico-cortical connections of the motor system with the observation of goal directed grasping movements
Abstract
Goal directed movements require the activation of parietal, premotor and primary motor areas. In monkeys, neurons of these areas become active also during the observation of movements performed by others, especially for coding the goal of the action (mirror system). Using bifocal transcranial magnetic stimulation (TMS) in healthy subjects, we tested whether the observation of goal directed reach to grasp actions may lead to specific changes in the short-latency connections linking key areas of the mirror system, such as the anterior intraparietal cortex (AIP) and the ventral premotor cortex (PMv), with the primary motor cortex (M1). We found that AIP-M1 and PMv-M1 cortico-cortical interactions were specifically activated when observing successful reaching to grasp goal directed actions, in which the hand posture was congruent with the goal of the action performed by the actor. On the other hand they were not modified when the same goal directed actions were performed wrongly with an inappropriate grasping posture. A similar profile of excitability was observed when testing specific intracortical facilitatory circuits in M1 (I(2)-waves), known to reflect the activity in cortico-cortical pathways transmitting information from PMv. We conclude that the simple observation of others' goal directed actions is able to induce specific neurophysiological changes in some cortico-cortical circuits of the human motor system.
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Ventral premotor and parietal regions homologous to macaque mirror neuron regions are causally involved in motor resonance.
“Ventral premotor and parietal regions that are homologous to macaque regions containing mirror neurons have been shown to be causally involved in motor resonance (Avenanti et al., 2007; Koch et al., 2010).”
From To imitate or not: Avoiding imitation involves preparatory inhibition of motor resonance (2014) · cites this paper as Koch et al., 2010
Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900 · see citing works
Action recognition in the premotor cortex
Gallese, V., Fadiga, L., Fogassi, L., & Rizzolatti, G. (1996) · Brain · doi:10.1093/brain/119.2.593 · Cited by 4,968 · see citing works
Understanding motor events: a neurophysiological study
di Pellegrino, G., Fadiga, L., Fogassi, L., Gallese, V., & Rizzolatti, G. (1992) · Experimental Brain Research · doi:10.1007/bf00230027 · Cited by 3,539 · see citing works
Neurophysiological mechanisms underlying the understanding and imitation of action
Rizzolatti, G., Fogassi, L., & Gallese, V. (2001) · Nature Reviews Neuroscience · doi:10.1038/35090060 · Cited by 3,302 · see citing works
Corticocortical inhibition in human motor cortex.
Kujirai, T., Caramia, M. D., Rothwell, J. C., Day, B. L., Thompson, P. D., Ferbert, A., Wroe, S. J., Asselman, P., & MARSDEN, C. D. (1993) · The Journal of Physiology · doi:10.1113/jphysiol.1993.sp019912 · Cited by 3,132 · see citing works
Cortical mechanisms of human imitation
Iacoboni, M., Woods, R. P., Brass, M., Bekkering, H., Mazziotta, J. C., & Rizzolatti, G. (1999) · Science · doi:10.1126/science.286.5449.2526 · Cited by 2,683 · see citing works
Action observation activates premotor and parietal areas in a somatotopic manner: an fMRI study
Buccino, G., Binkofski, F., Fink, G. R., Fadiga, L., Fogassi, L., Gallese, V., Seitz, R. J., Zilles, K., Rizzolatti, G., & Freund, H. ‐. (2001) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2001.01385.x · Cited by 2,488 · see citing works
Action observation activates premotor and parietal areas in a somatotopic manner: an fMRI study
Buccino, G., Binkofski, F., Fink, G. R., Fadiga, L., Fogassi, L., Gallese, V., Seitz, R. J., Zilles, K., Rizzolatti, G., & Freund, H. (2001) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2001.01385.x · Cited by 2,471 · see citing works
Motor facilitation during action observation: a magnetic stimulation study
Fadiga, L., Fogassi, L., Pavesi, G., & Rizzolatti, G. (1995) · Journal of Neurophysiology · doi:10.1152/jn.1995.73.6.2608 · Cited by 2,297 · see citing works
Grasping the intentions of others with one's own mirror neuron system
Iacoboni, M., Molnar-Szakacs, I., Gallese, V., Buccino, G., Mazziotta, J. C., & Rizzolatti, G. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030079 · Cited by 2,044 · cited 1× · see citing works
“…the same parietal and premotor regions during movement observation (Buccino, Binkofski, Fink, Fadiga, & Fogassi, 2001; Calvo-Merino, Glaser, Grèzes, Passingham, & Haggard, 2005; Grafton, Arbib, Fadiga, & Rizzolatti, 1996; Iacoboni et al., 2005; Iacoboni, Woods, Brass, Bekkering, & Mazziotta, 1999).”
Action Observation and Acquired Motor Skills: An fMRI Study with Expert Dancers
Calvo‐Merino, B., Glaser, D. E., Grèzes, J., Passingham, R. E., & Haggard, P. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhi007 · Cited by 1,991 · see citing works
Grasping objects: the cortical mechanisms of visuomotor transformation
Jeannerod, M., Arbib, M. A., Rizzolatti, G., & Sakata, H. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93921-j · Cited by 1,399 · see citing works
Rizzolatti, G., & Luppino, G. (2001) · Neuron · doi:10.1016/s0896-6273(01)00423-8 · Cited by 1,356 · see citing works
Endurance exercise performance: the physiology of champions
Joyner, M. J., & Coyle, E. F. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2007.143834 · Cited by 1,307 · see citing works
Single-Neuron Responses in Humans during Execution and Observation of Actions
Mukamel, R., Ekstrom, A. D., Kaplan, J., Iacoboni, M., & Fried, I. (2010) · Current Biology · doi:10.1016/j.cub.2010.02.045 · Cited by 1,178 · see citing works
Grafton, S., Arbib, M., Fadiga, L., & Rizzolatti, G. (1996) · Experimental Brain Research · doi:10.1007/bf00227183 · Cited by 1,045 · see citing works
Action anticipation and motor resonance in elite basketball players
Aglioti, S. M., Cesari, P., Romani, M., & Urgesi, C. (2008) · Nature Neuroscience · doi:10.1038/nn.2182 · Cited by 1,043 · see citing works
Murata, A., Gallese, V., Luppino, G., Kaseda, M., & Sakata, H. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.5.2580 · Cited by 841 · see citing works
Object Representation in the Ventral Premotor Cortex (Area F5) of the Monkey
Murata, A., Fadiga, L., Fogassi, L., Gallese, V., Raos, V., & Rizzolatti, G. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.4.2226 · Cited by 753 · see citing works
Castiello, U. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1744 · Cited by 621 · see citing works
Cortical Activity in Precision- Versus Power-Grip Tasks: An fMRI Study
Ehrsson, H. H., Fagergren, A., Jonsson, T., Westling, G., Johansson, R. S., & Forssberg, H. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.1.528 · Cited by 618 · see citing works
Human anterior intraparietal area subserves prehension
Binkofski, F., Dohle, C., Posse, S., Stephan, K. M., Hefter, H., Seitz, R. J., & Freund, H. J. (1998) · Neurology · doi:10.1212/wnl.50.5.1253 · Cited by 550 · see citing works
Strafella, A. P., & Paus, T. (2000) · NeuroReport · doi:10.1097/00001756-200007140-00044 · Cited by 504 · see citing works
Human motor cortex excitability during the perception of others’ action
Fadiga, L., Craighero, L., & Olivier, E. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.03.013 · Cited by 494 · see citing works
Ziemann, U., Tergau, F., Wassermann, E. M., Wischer, S., Hildebrandt, J., & Paulus, W. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.181bi.x · Cited by 464 · see citing works
Phase-specific modulation of cortical motor output during movement observation
Gangitano, M., Mottaghy, F. M., & Pascual-Leone, A. (2001) · Neuroreport · doi:10.1097/00001756-200105250-00038 · Cited by 446 · see citing works
Mirror neurons and their clinical relevance
Rizzolatti, G., Fabbri‐Destro, M., & Cattaneo, L. (2009) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0990 · Cited by 417 · see citing works
Shimazu, H., Maier, M. A., Cerri, G., Kirkwood, P., & Lemon, R. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4731-03.2004 · Cited by 304 · see citing works
Kraskov, A., Dancause, N., Quallo, M. M., Shepherd, S., & Lemon, R. N. (2009) · Neuron · doi:10.1016/j.neuron.2009.12.010 · Cited by 298 · see citing works
Somatic and motor components of action simulation
Avenanti, A., Bolognini, N., Maravita, A., & Aglioti, S. M. (2007) · Current Biology · doi:10.1016/j.cub.2007.11.045 · Cited by 244 · see citing works
Koch, G., Fernández‐del‐Olmo, M., Cheeran, B., Ruge, D., Schippling, S., Caltagirone, C., & Rothwell, J. C. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0598-07.2007 · Cited by 234 · see citing works
Self-citationKoch, G., Oliveri, M., Cheeran, B., Ruge, D., Gerfo, E. L., Salerno, S., Torriero, S., Marconi, B., Mori, F., Driver, J., et al. (2008) · Brain · doi:10.1093/brain/awn273 · Cited by 231 · see citing works
Self-citationInhibition in the human motor cortex is reduced just before a voluntary contraction
Reynolds, C. H., & Ashby, P. (1999) · Neurology · doi:10.1212/wnl.53.4.730 · Cited by 231 · see citing works
Davare, M., Lemon, R., & Olivier, E. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.152603 · Cited by 227 · see citing works
Koch, G., Franca, M., Fernández‐del‐Olmo, M., Cheeran, B., Milton, R. H., Saúco, M. Á., & Rothwell, J. C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1158-06.2006 · Cited by 226 · see citing works
Self-citationClark, S., Tremblay, F., & Ste‐Marie, D. M. (2003) · Neuropsychologia · doi:10.1016/s0028-3932(03)00144-1 · Cited by 225 · see citing works
Action Understanding Requires the Left Inferior Frontal Cortex
Pobric, G., & Hamilton, A. F. D. C. (2006) · Current Biology · doi:10.1016/j.cub.2006.01.033 · Cited by 224 · see citing works
Cattaneo, L., Sandrini, M., & Schwarzbach, J. V. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp291 · Cited by 222 · see citing works
Ventral premotor to primary motor cortical interactions during object-driven grasp in humans
Davare, M., Montague-Cardoso, K., Olivier, E., Rothwell, J. C., & Lemon, R. (2009) · Cortex · doi:10.1016/j.cortex.2009.02.011 · Cited by 199 · see citing works
Cattaneo, L., Caruana, F., Jezzini, A., & Rizzolatti, G. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2605-09.2009 · Cited by 173 · see citing works
Mars, R. B., Klein-Flügge, M. C., Neubert, F.-X., Olivier, E., Buch, E. R., Boorman, E. D., & Rushworth, M. F. S. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1396-09.2009 · Cited by 161 · see citing works
Urgesi, C., Candidi, M., Fabbro, F., Romani, M., & Aglioti, S. M. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04772.x · Cited by 160 · see citing works
Functional specificity of human premotor–motor cortical interactions during action selection
O’Shea, J., Sebastian, C. L., Boorman, E. D., Johansen‐Berg, H., & Rushworth, M. F. S. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05795.x · Cited by 151 · see citing works
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Koch, G., Cercignani, M., Pecchioli, C., Versace, V., Oliveri, M., Caltagirone, C., Rothwell, J., & Bozzali, M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.02.022 · Cited by 143 · see citing works
Self-citationKoch, G., Fernández‐del‐Olmo, M., Cheeran, B., Schippling, S., Caltagirone, C., Driver, J., & Rothwell, J. C. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0957-08.2008 · Cited by 137 · see citing works
Self-citationDifferential cortical activity for precision and whole‐hand visually guided grasping in humans
Begliomini, C., Wall, M. B., Smith, A. T., & Castiello, U. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05365.x · Cited by 115 · see citing works
Koch, G., & Rothwell, J. C. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.03.023 · Cited by 115 · see citing works
Self-citationBäumer, T., Schippling, S., Kroeger, J., Zittel, S., Koch, G., Thomalla, G., Rothwell, J. C., Siebner, H. R., Orth, M., & Münchau, A. M. (2009) · Clinical Neurophysiology · doi:10.1016/j.clinph.2009.07.035 · Cited by 108 · see citing works
Self-citationA cortico-cortical mechanism mediating object-driven grasp in humans
Cattaneo, L., Voss, M., Brochier, T. G., Prabhu, G., Wolpert, D. M., & Lemon, R. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409182102 · Cited by 93 · see citing works
Prabhu, G., Shimazu, H., Cerri, G., Brochier, T. G., Spinks, R. L., Maier, M. A., & Lemon, R. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.165571 · Cited by 92 · see citing works
Sensorimotor Control of Grasping : Physiology and Pathophysiology
Nowak, D. A., & Hermsdörfer, J. (2009) · JuSER (Forschungszentrum Jülich) · Cited by 62 · see citing works
Amassian, V. E., & Stewart, M. (2003) · Supplements to Clinical neurophysiology · doi:10.1016/s1567-424x(09)70214-4 · Cited by 46 · see citing works
Chapter 12 Generation of I waves in the human: spinal recordings
Lazzaro, V. D., Oliviero, A., Mazzone, P., Pilato, F., Saturno, E., Dileone, M., & Tonali, P. (2003) · Supplements to Clinical neurophysiology · doi:10.1016/s1567-424x(09)70215-6 · Cited by 12 · see citing works
Transcranial magnetic stimulation investigations of reaching and grasping movements
Koch, G., & Rothwell, J. C. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511581267.007 · Cited by 2 · see citing works
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Jacquet, P. O., & Avenanti, A. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht242 · Cited by 98 · see citing works
Cattaneo, L., Barchiesi, G., Tabarelli, D., Arfeller, C., Sato, M., & Glenberg, A. M. (2011) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq099 · Cited by 99 · see citing works
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Lee, S.-H., Kim, S.-S., & Lee, B. (2020) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2020.1831114 · Cited by 58 · see citing works
Koch, G. (2020) · Experimental Brain Research · doi:10.1007/s00221-020-05844-5 · Cited by 57 · see citing works
Self-citationMurakami, T., Restle, J., & Ziemann, U. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.03.034 · Cited by 57 · see citing works
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Abstract and concrete phrases processing differentially modulates cortico-spinal excitability
Scorolli, C., Jacquet, P. O., Binkofski, F., Nicoletti, R., Tessari, A., & Borghi, A. M. (2012) · Brain Research · doi:10.1016/j.brainres.2012.10.004 · Cited by 56 · see citing works
Hartwigsen, G., Bergmann, T. O., Herz, D. M., Angstmann, S., Karabanov, A. N., Raffin, E., Thielscher, A., & Siebner, H. R. (2015) · Progress in brain research · doi:10.1016/bs.pbr.2015.06.014 · Cited by 55 · see citing works
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Franca, M., Turella, L., Canto, R., Brunelli, N., Allione, L., Andreasi, N. G., Desantis, M., Marzoli, D., & Fadiga, L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049025 · Cited by 51 · see citing works
Loporto, M., Holmes, P. S., Wright, D. J., & McAllister, C. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064911 · Cited by 50 · see citing works
Fiori, F., Chiappini, E., Soriano, M., Paracampo, R., Romei, V., Borgomaneri, S., & Avenanti, A. (2016) · Scientific Reports · doi:10.1038/srep38396 · Cited by 50 · see citing works
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Feurra, M., Bianco, G., Polizzotto, N. R., Innocenti, I., Rossi, A., & Rossi, S. (2011) · Frontiers in Neural Circuits · doi:10.3389/fncir.2011.00010 · Cited by 42 · see citing works
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Cracco, E., De Coster, L., Andres, M., & Brass, M. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw059 · Cited by 38 · see citing works
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Murakami, T., Restle, J., & Ziemann, U. (2011) · Brain and Language · doi:10.1016/j.bandl.2011.09.005 · Cited by 26 · see citing works
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On a puzzle about relations between thought, experience and the motoric
Sinigaglia, C., & Butterfill, S. (2015) · Synthese · doi:10.1007/s11229-015-0672-x · Cited by 23 · see citing works
Valchev, N. S., Zijdewind, I., Keysers, C., Gazzola, V., Avenanti, A., & Maurits, N. M. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.11.030 · Cited by 22 · see citing works
Cantarero, G. L., Galea, J. M., Ajagbe, L., Salas, R. M. E., Willis, J., & Celnik, P. A. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00051 · Cited by 21 · see citing works
Moriuchi, T., Iso, N., Sagari, A., Ogahara, K., Kitajima, E., Tanaka, K., Tabira, T., & Higashi, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0114355 · Cited by 19 · see citing works
Betti, S., Castiello, U., Guerra, S., & Sartori, L. (2017) · PLoS ONE · doi:10.1371/journal.pone.0173114 · Cited by 20 · see citing works
Utility of TMS to understand the neurobiology of speech
Murakami, T., Ugawa, Y., & Ziemann, U. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00446 · Cited by 20 · see citing works
Cretu, A. L., Ruddy, K. L., Germann, M., & Wenderoth, N. (2019) · Journal of Neurophysiology · doi:10.1152/jn.00655.2018 · Cited by 20 · see citing works
Sartori, L., Betti, S., & Castiello, U. (2013) · Neuroreport · doi:10.1097/wnr.0b013e3283630a66 · Cited by 19 · see citing works
Early modulation of intra-cortical inhibition during the observation of action mistakes
Cardellicchio, P., Hilt, P. M., Olivier, E., Fadiga, L., & D’Ausilio, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-20245-z · Cited by 19 · see citing works
Emerging of new bioartificial corticospinal motor synergies using a robotic additional thumb
Rossi, S., Salvietti, G., Neri, F., Romanella, S. M., Cinti, A., Sinigaglia, C., Ulivelli, M., Baldi, T. L., Santarnecchi, E., & Prattichizzo, D. (2021) · Scientific Reports · doi:10.1038/s41598-021-97876-2 · Cited by 19 · see citing works
Chiappini, E., Turrini, S., Zanon, M., Marangon, M., Borgomaneri, S., & Avenanti, A. (2024) · Brain stimulation · doi:10.1016/j.brs.2024.02.011 · Cited by 18 · see citing works
Decroix, J., Borgomaneri, S., Kalénine, S., & Avenanti, A. (2020) · Cortex · doi:10.1016/j.cortex.2020.08.004 · Cited by 18 · see citing works
Casarotto, A., Dolfini, E., Fadiga, L., Koch, G., & D’Ausilio, A. (2023) · The Journal of Physiology · doi:10.1113/jp284500 · Cited by 17 · see citing works
Self-citationCraighero, L., Zorzi, V. A., Canto, R., & Franca, M. (2014) · Visual Cognition · doi:10.1080/13506285.2014.904460 · Cited by 16 · see citing works
Taschereau‐Dumouchel, V., Hétu, S., Michon, P., Vachon‐Presseau, É., Massicotte, E., Beaumont, L. D., Fecteau, S., Poirier, J., Mercier, C., Chagnon, Y. C., et al. (2016) · Scientific Reports · doi:10.1038/srep34907 · Cited by 16 · see citing works
An Emotion-Enriched Context Influences the Effect of Action Observation on Cortical Excitability
Lagravinese, G., Bisio, A., Ferrari, A. R. D., Pelosin, E., Ruggeri, P., Bove, M., & Avanzino, L. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00504 · Cited by 15 · see citing works
Moriuchi, T., Matsuda, D., Nakamura, J., Matsuo, T., Nakashima, A., Nishi, K., Fujiwara, K., Iso, N., Nakane, H., & Higashi, T. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00010 · Cited by 14 · see citing works
The left side of motor resonance
Sartori, L., Begliomini, C., Panozzo, G., Garolla, A., & Castiello, U. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00702 · Cited by 14 · see citing works
Qi, F., Nitsche, M. A., & Zschorlich, V. R. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00069 · Cited by 13 · see citing works
Nogueira‐Campos, A. A., Saunier, G., Della‐Maggiore, V., de Oliveira, L. A. S., Rodrigues, É. C., & Vargas, C. D. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00434 · Cited by 11 · see citing works
Selective enhancement of motor cortical plasticity by observed mirror-matched actions
Sale, M. V., & Mattingley, J. B. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.02.009 · Cited by 12 · see citing works
Changes in corticospinal excitability associated with motor learning by observing
McGregor, H. E., Vesia, M., Rinchon, C., Chen, R. E., & Gribble, P. L. (2018) · Experimental Brain Research · doi:10.1007/s00221-018-5339-7 · Cited by 11 · see citing works
Guidali, G., & Bolognini, N. (2025) · Brain Sciences · doi:10.3390/brainsci15030257 · Cited by 10 · see citing works
Jegatheeswaran, G., Vesia, M., Isayama, R., Gunraj, C. A., & Chen, R. E. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.05.026 · Cited by 10 · see citing works
Pedullà, L., Gervasoni, E., Bisio, A., Biggio, M., Ruggeri, P., Avanzino, L., & Bove, M. (2020) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsaa021 · Cited by 10 · see citing works
Observation of implied motion in a work of art modulates cortical connectivity and plasticity
Concerto, C., Infortuna, C., Mineo, L., Pereira, M., Freedberg, D., Chusid, E., Aguglia, E., & Battaglia, F. (2016) · Journal of Exercise Rehabilitation · doi:10.12965/jer.1632656.328 · Cited by 10 · see citing works
Murteira, A., Sowman, P. F., & Nickels, L. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00920 · Cited by 9 · see citing works
Grip-dependent cortico-spinal excitability during grasping imagination and execution
Cesari, P., Pizzolato, F., & Fiorio, M. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.04.019 · Cited by 9 · see citing works
Goldenkoff, E. R., Mashni, A., Michon, K. J., Lavis, H., & Vesia, M. (2020) · Journal of Visualized Experiments · doi:10.3791/60706 · Cited by 9 · see citing works
Picardi, M., Guidali, G., Caronni, A., Rota, V., Corbo, M., & Bolognini, N. (2025) · Scientific Reports · doi:10.1038/s41598-025-98595-8 · Cited by 7 · see citing works
The role of the motor system in action imagination and comprehension
DuPont, W. H., Madden-Lombardi, C., Perrone‐Bertolotti, M., Palluel-Germain, R., & Lebon, F. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106392 · Cited by 6 · see citing works
The role of dorsal premotor cortex in joint action inhibition
Dolfini, E., Cardellicchio, P., Fadiga, L., & D’Ausilio, A. (2024) · Scientific Reports · doi:10.1038/s41598-024-54448-4 · Cited by 6 · see citing works
Visual–Motor Interactions during Action Observation Are Shaped by Cognitive Context
Bortoletto, M., Baker, K. S., Mattingley, J. B., & Cunnington, R. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00431 · Cited by 6 · see citing works
Yang, Y.-P., & Kim, S. (2017) · Journal of the Korean Society of Physical Medicine · doi:10.13066/kspm.2017.12.1.67 · Cited by 6 · see citing works
Muscle-specific modulation of indirect inputs to primary motor cortex during action observation
Cretu, A. L., Ruddy, K. L., Post, A., & Wenderoth, N. (2020) · Experimental Brain Research · doi:10.1007/s00221-020-05801-2 · Cited by 6 · see citing works
Ramakrishnan, P. (2015) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000180 · Cited by 6 · see citing works
The Effect of Action Observation Training on Balance in Patients with Chronic Stroke
Choi, H.-S., & Nam, K.-W. (2014) · Journal of the Korea Academia-Industrial cooperation Society · doi:10.5762/kais.2014.15.6.3759 · Cited by 5 · see citing works
Soriano, M., Koul, A., Becchio, C., & Cavallo, A. (2019) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2019.107205 · Cited by 5 · see citing works
Kim, S.-S., & Lee, B. (2015) · Journal of Physical Therapy Science · doi:10.1589/jpts.27.1379 · Cited by 5 · see citing works
Scanpath EEG dynamic, a new perspective for neuroaesthetic connoisseurship in paintings
Chéron, G., & Maere, J. D. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1442623 · Cited by 4 · see citing works
Kitamura, M., Yamamoto, K., Oshima, A., & Kamibayashi, K. (2023) · PLoS ONE · doi:10.1371/journal.pone.0292060 · Cited by 3 · see citing works
The Role of the Putative Mirror Neuron System in Language Comprehension
Traxler, M. J. (2013) · Language and Linguistics Compass · doi:10.1111/lnc3.12040 · Cited by 3 · see citing works
The do‐able solution to the interface problem
Levy, Y. (2025) · Philosophy and Phenomenological Research · doi:10.1111/phpr.13139 · Cited by 2 · see citing works
Turrini, S., Tarasi, L., Bevacqua, N., Fiori, F., Zago, S., Arcara, G., Candidi, M., Romei, V., & Avenanti, A. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0340-25.2025 · Cited by 3 · see citing works
The causal interaction in human basal ganglia
Rodriguez‐Sabate, C., González, A., Pérez, J. C., Moráles, I., & Rodrı́guez, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-92490-8 · Cited by 2 · see citing works
Balancing the excitability of M1 circuitry during movement observation without overt replication
Arias, P., Robles‐García, V., Corral-Bergantiños, Y., Espinosa, N., Mordillo‐Mateos, L., Grieve, K. L., Oliviero, A., & Cudeiro, J. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00316 · Cited by 2 · see citing works
The effects of motor imagery training on brain waves in persons post-stroke
Yoon, H.-W., & Kim, S.-S. (2015) · Physical therapy rehabilitation science · doi:10.14474/ptrs.2015.4.1.1 · Cited by 2 · see citing works
Jung, K.-M., Joo, M. C., Jung, Y., Lee, K., Chae, S.-M., & Choi, J.-W. (2018) · The Journal of Korean Society of Occupational Therapy · doi:10.14519/jksot.2018.26.3.08 · Cited by 2 · see citing works
Applications of TMS to Study Brain Connectivity
Cantarero, G. L., & Celnik, P. A. (2015) · Brain stimulation · doi:10.1002/9781118568323.ch11 · Cited by 2 · see citing works
Kohler, N., Czepiel, A. M., de Manzano, Ö., Novembre, G., Keller, P. E., Villringer, A., & Sammler, D. (2025) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2025.1543131 · Cited by 1 · see citing works
Cattaneo, L., Nunes, S., Giampiccolo, D., Caro, V. D., Basaldella, F., Badari, A., Tagliaferri, M., Squintani, G. M., & Sala, F. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121621 · Cited by 1 · see citing works
Timing and circuit engagement shape state-dependent plasticity in the ventral premotor-motor pathway
Turrini, S., Amadori, A., Zago, S., Arcara, G., & Avenanti, A. (2026) · Clinical Neurophysiology · doi:10.1016/j.clinph.2026.2112352 · Cited by 1 · see citing works
- Authors
- Koch, G., Versace, V., Bonnì, S., Lupo, F., Gerfo, E. L., Oliveri, M., & Caltagirone, C.
- Affiliations
- University of Rome Tor Vergata (IT)
- Fondazione Santa Lucia (IT)
- Corresponding author
- Koch, Giacomo
- Venue
- Neuropsychologia
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 48
- Issue
- 12
- Pages
- 3513-3520
- ISSN
- 0028-3932 (ISSN-L)
- OpenAlex
- W2043841604
- Cited by
- 119
- References
- 53
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 8 · 2019: 7 · 2018: 7 · 2017: 6 · 2016: 8 · 2015: 14 · 2014: 12 · 2013: 11 · 2012: 10
- FWCI
- 13.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychologia (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Keywords
- mirror system, corticocortical connections, ventral premotor cortex, primary motor cortex, action observation
- MeSH terms
- Adult, Brain Mapping, Cerebral Cortex, Electromyography, Female, Goals, Humans, Male, Movement, Neural Pathways, Photic Stimulation, Psychomotor Performance, Muscle, Skeletal, Hand Strength, Evoked Potentials, Motor, Observation, Transcranial Magnetic Stimulation, Young Adult
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