Attention modification program in individuals with generalized anxiety disorder
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Research suggests that individuals with generalized anxiety disorder (GAD) show an attention bias for threat-relevant information. However, few studies have examined the causal role of attention bias in the maintenance of anxiety and whether modification of such biases may reduce pathological anxiety symptoms. In the present article, the authors tested the hypothesis that an 8-session attention modification program would (a) decrease attention bias to threat and (b) reduce symptoms of GAD. Participants completed a probe detection task by identifying letters (E or F) replacing one member of a pair of words. The authors trained attention by including a contingency between the location of the probe and the nonthreat word in one group (Attention Modification Program; AMP) and not in the other (attention control condition; ACC). Participants in the AMP showed change in attention bias and a decrease in anxiety, as indicated by both self-report and interviewer measures. These effects were not present in the ACC group. These results are consistent with the hypothesis that attention plays a causal role in the maintenance of GAD and suggest that altering attention mechanisms may effectively reduce anxiety.
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Recent ABM studies find increased ability to improve directed attention away from hypervigilant threat focus and subsequent symptom/impairment improvement, particularly for anxiety disorders.
“Recent attentional bias modification (ABM) studies find an increased ability to improve directed attention away from a hypervigilant threat focus and subsequent improvement in symptoms and impairment, particularly for anxiety disorders”
From United we stand: emphasizing commonalities across cognitive-behavioral therapies. (2013) · cites this paper as Amir et al., 2009
The Discussion reports that the attention modification group showed less bias toward threat and fewer anxiety symptoms than the control group. The Results also report that more participants in that group no longer met diagnostic criteria for generalized anxiety disorder. The paper does not report a separate improvement in impairment, and its findings directly concern GAD rather than anxiety disorders broadly. (LLM, conf=0.85)
Experimental — accuracy not yet measuredNon-CBT treatments such as mindfulness-based interventions or bias modification programs have shown some promise in reducing GAD severity but often did not enroll GAD patients with prominent depression, restore high endstate functioning, or significantly resolve depression when present.
“non-CBT treatments such as mindfulness-based interventions consisting solely of meditative practice71–73 or bias modification programs74, 75, which may be seen as requiring less effort to deliver, have shown some promise in reducing GAD severity but often did not enroll GAD patients with prominent levels of depression72), restore patients to high endstate functioning75, 76, or significantly resolv”
From AN OPEN TRIAL OF EMOTION REGULATION THERAPY FOR GENERALIZED ANXIETY DISORDER AND COOCCURRING DEPRESSION. (2015) · cites this paper as [74]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredBriefer, more homogeneous interventions have emerged.
“briefer, more homogeneous interventions have emerged (e.g., ABM; Amir et al., 2009)”
From United we stand: emphasizing commonalities across cognitive-behavioral therapies. (2013) · cites this paper as Amir et al., 2009
Simple computer-based cognitive bias training tasks alter processing biases in non-clinical and clinical groups.
“These simple, computer-based training tasks have been found to alter processing biases (eg, in attention) in both non-clinical (Browning et al, 2010b; MacLeod et al, 2002) and clinical groups (Amir et al, 2009)”
From Using an Experimental Medicine Model to Explore Combination Effects of Pharmacological and Cognitive Interventions for Depression and Anxiety (2011) · cites this paper as Amir et al, 2009
After promising preclinical studies, first successful clinical applications of attentional bias modification have been reported in targeted prevention and in clinically anxious patient groups, with maintenance of clinical improvement four months after training.
“After promising preclinical studies (MacLeod et al., 2002), first successful clinical applications have been reported in targeted prevention (See et al., 2009) and in clinically anxious patient groups (Amir et al., 2009;Schmidt et al., 2009), and targeted prevention (See et al., 2009) with maintenance of clinical improvement reported four months after the training (Schmidt et al., 2009).”
From Addiction, adolescence, and the integration of control and motivation (2011) · cites this paper as Amir et al., 2009
Reducing negative attentional biases in clinically anxious populations improves anxiety.
“while reducing negative attentional biases in clinically anxious populations improves anxiety (5,6).”
From Lateral prefrontal cortex mediates the cognitive modification of attentional bias (2010) · cites this paper as [5]
Interpretation of findings of AB change is complicated by the methodological limitation that many ABM studies use the same or similar paradigm to modify and assess AB.
“Third, interpretation of findings of AB change is complicated by a methodological limitation of many ABM studies, which is the use of the same or similar paradigm to modify and assess AB (e.g., as noted by Amir et al., 2009;Cristea, Kok, et al., 2015).”
From Anxiety and attention to threat: cognitive mechanisms and treatment with attention bias modification (2016) · cites this paper as Amir et al., 2009
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- Authors
- Amir, N., Beard, C., Burns, M., & Bomyea, J.
- Affiliations
- San Diego State University (US)
- University of Georgia (US)
- Venue
- Journal of Abnormal Psychology
- Published
- 2009-02
- Volume
- 118
- Issue
- 1
- Pages
- 28-33
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- PMC
- PMC2645540
- OpenAlex
- W2039854536
- Cited by
- 539
- References
- 27
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 8 · 2023: 10 · 2022: 10 · 2021: 21 · 2020: 23 · 2019: 38 · 2018: 31 · 2017: 30 · 2016: 30 · 2015: 52 · 2014: 56 · 2013: 37 · 2012: 45
- FWCI
- 74.06
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (R34 MH073004-01; R34 MH077129-01)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- generalized anxiety disorder, attentional bias, threat attention, anxiety maintenance, attention training, anxiety symptoms
- MeSH terms
- Adult, Anxiety Disorders, Attention, Educational Status, Female, Humans, Male, Mental Processes, Severity of Illness Index, Vocabulary, Cognitive Behavioral Therapy, Diagnostic and Statistical Manual of Mental Disorders
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