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Impulsive choice, as measured in a delay discounting paradigm, remains stable after chronic heroin administration

Harty, Seth C., Whaley, Jamar E., Halperin, Jeffrey M., Ranaldi, Robert·2011·Pharmacology Biochemistry and Behavior
DOI 10.1016/j.pbb.2011.02.004
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Abstract

Heroin addicts display poorer impulse control than non-addicts, however it is not known if high impulsivity is a function of chronic heroin intake or a pre-disposing vulnerability for heroin addiction. Using animal models, relatively few studies have examined changes in impulsive choice as a function of chronic drug. The objective of this study was to measure alterations in impulsive choice through a delay discounting paradigm, as a function of chronic heroin administration. Animals were trained on a series of delay discounting sessions. Each session contained 5 blocks of trials. Blocks started with 2 forced, followed by 6 free choice trials. Pressing one lever resulted in the delivery of a small immediate (1 food pellet) reward and another lever in a large delayed (5 pellets) reward. Sessions consisted of the 3 ascending delay sequences in seconds. On the terminal sequence (0, 10, 20, 40, and 60s) animals exhibited a reversal of reward choice pattern of responding that allowed for the calculation of an indifference point (IP). After animals showed stable IPs they were treated with either heroin or saline for 12 days. Three days after the last injection animals were again placed in operant chambers and experienced the terminal delay discounting sequence at which time IPs were reassessed. Heroin-treated animals exhibited significant progressive increases in locomotor activity. Groups did not differ in IPs or performance across delay conditions during either before or after chr…

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  1. Baker, 2003, Delay discounting in current and never-before cigarette smokers: similarities and differences across commodity, sign, and magnitude, J Abnorm Psychol, 112, 382, 10.1037/0021-843X.112.3.382 · DOI · Paper page
  2. Belin, 2008, High impulsivity predicts the switch to compulsive cocaine-taking, Science, 320, 1352, 10.1126/science.1158136 · DOI · Paper page
  3. Bornovalova, 2005, Differences in impulsivity and risk-taking propensity between primary users of crack cocaine and primary users of heroin in a residential substance-use program, Exp Clin Psychopharmacol, 13, 311, 10.1037/1064-1297.13.4.311 · DOI
  4. Cardinal, 2000, The effects of d-amphetamine, chlordiazepoxide, alpha-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement in rats, Psychopharmacology (Berl), 152, 362, 10.1007/s002130000536 · DOI
  5. Coffey, 2003, Impulsivity and rapid discounting of delayed hypothetical rewards in cocaine-dependent individuals, Exp Clin Psychopharmacol, 11, 18, 10.1037/1064-1297.11.1.18 · DOI · Paper page
  6. Dalley, 2005, Attentional and motivational deficits in rats withdrawn from intravenous self-administration of cocaine or heroin, Psychopharmacology (Berl), 182, 579, 10.1007/s00213-005-0107-3 · DOI
  7. Dalley, 2007, Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement, Science, 315, 1267, 10.1126/science.1137073 · DOI · Paper page
  8. Evenden, 1999, Varieties of impulsivity, Psychopharmacology (Berl), 146, 348, 10.1007/PL00005481 · DOI · Paper page
  9. Evenden, 1996, The pharmacology of impulsive behaviour in rats: the effects of drugs on response choice with varying delays of reinforcement, Psychopharmacology (Berl), 128, 161, 10.1007/s002130050121 · DOI
  10. Hser, 2008, Comparing the dynamic course of heroin, cocaine, and methamphetamine use over 10years, Addict Behav, 33, 1581, 10.1016/j.addbeh.2008.07.024 · DOI
  11. Hser, 2008, Contrasting trajectories of heroin, cocaine, and methamphetamine use, J Addict Dis, 27, 13, 10.1080/10550880802122554 · DOI
  12. Kalivas, 1987, Sensitization to repeated morphine injection in the rat: possible involvement of A10 dopamine neurons, J Pharmacol Exp Ther, 241, 204, 10.1016/S0022-5347(25)00345-3 · DOI
  13. Madden, 1999, Discounting of delayed rewards in opioid-dependent outpatients: exponential or hyperbolic discounting functions?, Exp Clin Psychopharmacol, 7, 284, 10.1037/1064-1297.7.3.284 · DOI
  14. McNamara, 2010, Trait-like impulsivity does not predict escalation of heroin self-administration in the rat, Psychopharmacology, 212, 453, 10.1007/s00213-010-1974-9 · DOI
  15. Nestby, 1997, Striatal dopamine receptors in rats displaying long-term behavioural sensitization to morphine, Synapse, 27, 262, 10.1002/(SICI)1098-2396(199711)27:3<262::AID-SYN10>3.0.CO;2-W · DOI
  16. Paine, 2003, Effects of chronic cocaine on impulsivity: relation to cortical serotonin mechanisms, Behav Brain Res, 147, 135, 10.1016/S0166-4328(03)00156-6 · DOI
  17. Perry, 2007, Impulsivity (delay discounting) for food and cocaine in male and female rats selectively bred for high and low saccharin intake, Pharmacol Biochem Behav, 86, 822, 10.1016/j.pbb.2007.03.012 · DOI
  18. Perry, 2008, Impulsive choice as a predictor of acquisition of IV cocaine self-administration and reinstatement of cocaine-seeking behavior in male and female rats, Exp Clin Psychopharmacol, 16, 165, 10.1037/1064-1297.16.2.165 · DOI · Paper page
  19. Ranaldi, 2009, Repeated heroin in rats produces locomotor sensitization and enhances appetitive Pavlovian and instrumental learning involving food reward, Pharmacol Biochem Behav, 91, 351, 10.1016/j.pbb.2008.08.006 · DOI
  20. Richards, 1999, Effects of methamphetamine on the adjusting amount procedure, a model of impulsive behavior in rats, Psychopharmacology (Berl), 146, 432, 10.1007/PL00005488 · DOI · Paper page
  21. Roesch, 2007, Previous cocaine exposure makes rats hypersensitive to both delay and reward magnitude, J Neurosci, 27, 245, 10.1523/JNEUROSCI.4080-06.2007 · DOI
  22. Setlow, 2009, Effects of chronic administration of drugs of abuse on impulsive choice (delay discounting) in animal models, Behav Pharmacol, 20, 380, 10.1097/FBP.0b013e3283305eb4 · DOI
  23. Simon, 2007, Cocaine exposure causes long-term increases in impulsive choice, Behav Neurosci, 121, 543, 10.1037/0735-7044.121.3.543 · DOI
  24. Spanagel, 1993, Modulation of morphine-induced sensitization by endogenous kappa opioid systems in the rat, Neurosci Lett, 153, 232, 10.1016/0304-3940(93)90329-J · DOI
  25. Stanis, 2008, Dissociation between long-lasting behavioral sensitization to amphetamine and impulsive choice in rats performing a delay-discounting task, Psychopharmacology (Berl), 199, 539, 10.1007/s00213-008-1182-z · DOI
  26. Vanderschuren, 2000, Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies, Psychopharmacology (Berl), 151, 99, 10.1007/s002130000493 · DOI
  27. Vuchinich, 1998, Hyperbolic temporal discounting in social drinkers and problem drinkers, Exp Clin Psychopharmacol, 6, 292, 10.1037/1064-1297.6.3.292 · DOI · Paper page
  28. Wilhelm, 2008, Rats bred for high alcohol drinking are more sensitive to delayed and probabilistic outcomes, Genes Brain Behav, 7, 705, 10.1111/j.1601-183X.2008.00406.x · DOI
  29. Winstanley, 2007, DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction, J Neurosci, 27, 10497, 10.1523/JNEUROSCI.2566-07.2007 · DOI

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Metadata

Authors
Harty, S. C., Whaley, J. E., Halperin, J. M., & Ranaldi, R.
Venue
Pharmacology Biochemistry and Behavior
Publisher
Elsevier BV
Published
2011-05
Volume
98
Issue
3
Pages
337-340
ISSN
0091-3057
DOI
10.1016/j.pbb.2011.02.004
Cited by
28
References
4
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Impulsive choice, as measured in a delay discounting paradigm, remains stable after chronic heroin administration. https://app.cochat.ai/papers/10.1016/j.pbb.2011.02.004
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Harty, S. C., Whaley, J. E., Halperin, J. M., & Ranaldi, R. (2011). Impulsive choice, as measured in a delay discounting paradigm, remains stable after chronic heroin administration. Pharmacology Biochemistry and Behavior. https://doi.org/10.1016/j.pbb.2011.02.004