Cited by 75Lipid metabolism and disordersDiabetes, Cardiovascular Risks, and LipoproteinsPhysical Activity and Health

Physical activity and postprandial lipidemia: Are energy expenditure and lipoprotein lipase activity the real modulators of the positive effect?

Peddie, Meredith C., Rehrer, Nancy J., Perry, Tracy L.·2012·Progress in Lipid Research

Abstract

Historically, the link between elevated cholesterol and increased risk of cardiovascular disease has been based on fasting measurements. This is appropriate for total, low-density lipoprotein and high-density lipoprotein cholesterol. However, triglyceride concentrations vary considerably throughout the day in response to the regular consumption of food and drink. Recent findings indicate that postprandial triglyceride concentrations independently predict future cardiovascular risk. Potential modulators of postprandial lipidemia include meal composition and physical activity. Early cross sectional studies indicated that physically active individuals had a lower postprandial lipidemic response compared to inactive individuals. However, the effect of physical activity on postprandial lipidemia is an acute phenomenon, which dissipates within 60 h of a single bout of exercise. Total exercise induced energy expenditure, rather than duration or intensity of the physical activity is commonly reported to be a potent modulator of postprandial lipidemia. However, the pooled results of studies in this area suggest that energy expenditure exerts most of its influence on fasting triglyceride concentrations rather than on the incremental change in triglyceride concentrations seen following meal consumption. It seems more likely that energy expenditure is one component of a multifactorial list of mediators that may include local muscle contractile activity, and other yet to be elucidated mechanisms.

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Crossref · 10.1016/j.plipres.2011.11.002

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  • Substantial lowering of postprandial triglyceride level occurred when subjects exercised before a high-fat diet, for longer periods and more intensively.

    “there was substantial lowering of postprandial TG level.”

    From Effects of aerobic exercise on lipids and lipoproteins (2017) · cites this paper as [56]

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Authors
Peddie, M. C., Rehrer, N. J., & Perry, T. L.
Affiliations
University of Otago (NZ)
Corresponding author
Perry, Tracy L.
Venue
Progress in Lipid Research
Publisher
Elsevier BV
Published
2012-01
Volume
51
Issue
1
Pages
11-22
ISSN
0163-7827 (ISSN-L)
OpenAlex
W2035183973
Cited by
75
References
134
Citations by year
2025: 2 · 2024: 2 · 2023: 2 · 2022: 7 · 2021: 5 · 2020: 11 · 2019: 9 · 2018: 2 · 2017: 9 · 2016: 6 · 2015: 5 · 2014: 4 · 2013: 9 · 2012: 2
FWCI
0.81
Type
journal article
Language
en
Open access
closed
Locations
  • Progress in Lipid Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
Keywords
physical activity, energy expenditure, lipoprotein lipase, postprandial triglycerides, cardiovascular risk, fasting triglycerides, meal composition
MeSH terms
Animals, Diet, Energy Metabolism, Humans, Hyperlipidemias, Lipoprotein Lipase, Motor Activity, Postprandial Period

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