Physical activity and postprandial lipidemia: Are energy expenditure and lipoprotein lipase activity the real modulators of the positive effect?
Abstract
Historically, the link between elevated cholesterol and increased risk of cardiovascular disease has been based on fasting measurements. This is appropriate for total, low-density lipoprotein and high-density lipoprotein cholesterol. However, triglyceride concentrations vary considerably throughout the day in response to the regular consumption of food and drink. Recent findings indicate that postprandial triglyceride concentrations independently predict future cardiovascular risk. Potential modulators of postprandial lipidemia include meal composition and physical activity. Early cross sectional studies indicated that physically active individuals had a lower postprandial lipidemic response compared to inactive individuals. However, the effect of physical activity on postprandial lipidemia is an acute phenomenon, which dissipates within 60 h of a single bout of exercise. Total exercise induced energy expenditure, rather than duration or intensity of the physical activity is commonly reported to be a potent modulator of postprandial lipidemia. However, the pooled results of studies in this area suggest that energy expenditure exerts most of its influence on fasting triglyceride concentrations rather than on the incremental change in triglyceride concentrations seen following meal consumption. It seems more likely that energy expenditure is one component of a multifactorial list of mediators that may include local muscle contractile activity, and other yet to be elucidated mechanisms.
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Substantial lowering of postprandial triglyceride level occurred when subjects exercised before a high-fat diet, for longer periods and more intensively.
“there was substantial lowering of postprandial TG level.”
From Effects of aerobic exercise on lipids and lipoproteins (2017) · cites this paper as [56]
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Effects of aerobic exercise on lipids and lipoproteins
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Self-citationPhysical activity during COVID-19 induced lockdown: recommendations
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The Latest on the Effect of Prior Exercise on Postprandial Lipaemia
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Acute High-Intensity Interval Running Reduces Postprandial Lipemia in Boys
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Different Patterns of Walking and Postprandial Triglycerides in Older Women
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Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men
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Heterogeneity of muscle activity during sedentary behavior
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Summation of blood glucose and TAG to characterise the ‘metabolic load index’
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Acute Exercise and Postprandial Lipemia in Young People
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High-Intensity Interval Exercise and Postprandial Triacylglycerol
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An Update on Accumulating Exercise and Postprandial Lipaemia: Translating Theory Into Practice
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Effect of sprint interval versus continuous cycling on postprandial lipaemia
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Postprandial Metabolism and Vascular Function: Impact of Aging and Physical Activity Level
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Recreational football practice attenuates postprandial lipaemia in normal and overweight individuals
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Do Running and Strength Exercises Reduce Daily Muscle Inactivity Time?
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Postprandial Metabolism and Physical Activity in Asians: A Narrative Review
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The accumulation of exercise and postprandial endothelial function in boys
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Exercise Energy Expenditure and Postprandial Lipemia in Girls
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Concordant and divergent strategies to improve postprandial glucose and lipid metabolism
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Exercise to Lower Postprandial Lipemia: Why, When, What and How
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Short Sprints Accumulated at School Modulate Postprandial Metabolism in Boys
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Increased Meal Frequency With Exercise Mitigates Postprandial Triacylglycerol.
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Effects of acute and chronic stair-climbing exercise on metabolic health: A systematic review
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Prior arm-crank exercise has no effect on postprandial lipaemia in nondisabled adults
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Interaction Between Diet and Physical Activity in Older People
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Sedentary behavior: Is it time to break up with your chair?
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중년남성의 비만병에 따른 만성질환과 신체활동량의 연관성: 2019~2022년 국민건강영양조사 자료
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- Authors
- Peddie, M. C., Rehrer, N. J., & Perry, T. L.
- Affiliations
- University of Otago (NZ)
- Corresponding author
- Perry, Tracy L.
- Venue
- Progress in Lipid Research
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 51
- Issue
- 1
- Pages
- 11-22
- ISSN
- 0163-7827 (ISSN-L)
- OpenAlex
- W2035183973
- Cited by
- 75
- References
- 134
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 2 · 2022: 7 · 2021: 5 · 2020: 11 · 2019: 9 · 2018: 2 · 2017: 9 · 2016: 6 · 2015: 5 · 2014: 4 · 2013: 9 · 2012: 2
- FWCI
- 0.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Progress in Lipid Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Keywords
- physical activity, energy expenditure, lipoprotein lipase, postprandial triglycerides, cardiovascular risk, fasting triglycerides, meal composition
- MeSH terms
- Animals, Diet, Energy Metabolism, Humans, Hyperlipidemias, Lipoprotein Lipase, Motor Activity, Postprandial Period
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