CoChat
Sign Up
Cited by 216Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology ResearchNeural and Behavioral Psychology Studies

The DOI matches its Crossref record; 323 of the 326 references it cites were found in a registry or an index.

Modulators in concert for cognition: Modulator interactions in the prefrontal cortex

Open access
Briand, Lisa A., Gritton, Howard, Howe, William M., Young, Damon A., Sarter, Martin·2007·Progress in Neurobiology
DOI 10.1016/j.pneurobio.2007.06.007PMC PMC2080765
Open this paper in CoChat — free account

Abstract

Research on the regulation and function of ascending noradrenergic, dopaminergic, serotonergic, and cholinergic systems has focused on the organization and function of individual systems. In contrast, evidence describing co-activation and interactions between multiple neuromodulatory systems has remained scarce. However, commonalities in the anatomical organization of these systems and overlapping evidence concerning the post-synaptic effects of neuromodulators strongly suggest that these systems are recruited in concert; they influence each other and simultaneously modulate their target circuits. Therefore, evidence on the regulatory and functional interactions between these systems is considered essential for revealing the role of neuromodulators. This postulate extends to contemporary neurobiological hypotheses of major neuropsychiatric disorders. These hypotheses have focused largely on aberrations in the integrity or regulation of individual ascending modulatory systems, with little regard for the likely possibility that dysregulation in multiple ascending neuromodulatory systems and their interactions contribute essentially to the symptoms of these disorders. This review will paradigmatically focus on neuromodulator interactions in the PFC and be further constrained by an additional focus on their role in cognitive functions. Recent evidence indicates that individual neuromodulators, in addition to their general state-setting or gating functions, encode specific cognitive operations, further substantiating the importance of research concerning the parallel recruitment of neuromodulator systems and interactions between these systems.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.pneurobio.2007.06.007

Cites

323 of 323 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Items 201–323 of 323

Flagged first, then by citations

3 of the 326 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. Grillner, 2000, Nicotine-induced excitation of midbrain dopamine neurons in vitro involves ionotropic glutamate receptor activation, Synapse, 38, 1, 10.1002/1098-2396(200010)38:1<1::AID-SYN1>3.0.CO;2-A · DOI
  2. Malone, 2004, Cortical projections of rat basal forebrain neurons: lack of axonal collateralization and similar topography of cholinergic and noncholinergic projections, J. Sleep Sleep Dis. Res., 27, A10

Cited by

Sorted by citations

See all 216

Related

See all

Metadata

Authors
Briand, L. A., Gritton, H., Howe, W. M., Young, D. A., & Sarter, M.
Affiliations
University of Michigan (US)
Corresponding author
Sarter, Martin
ORCID
Venue
Progress in Neurobiology
Publisher
Elsevier BV
Published
2007-10
Volume
83
Issue
2
Pages
69-91
ISSN
0301-0082 (ISSN-L)
DOI
10.1016/j.pneurobio.2007.06.007
PMC
PMC2080765
OpenAlex
W1976205295
Cited by
216
References
326
Citations by year
2026: 4 · 2025: 17 · 2024: 9 · 2023: 8 · 2022: 15 · 2021: 11 · 2020: 8 · 2019: 6 · 2018: 7 · 2017: 8 · 2016: 6 · 2015: 12 · 2014: 11 · 2013: 16 · 2012: 17
FWCI
1.44
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Progress in Neurobiology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute of Mental Health (K02MH01072, R01MH063114, R01MH057436, MH 057436, MH073600, MH 063114, K02MH001072, R03MH073600)
  • National Institute of Neurological Disorders and Stroke (NS37026, R01NS037026)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
prefrontal cortex, noradrenergic system, dopaminergic system, serotonergic system, cholinergic system, cognitive function, neuropsychiatric disorders
MeSH terms
Animals, Cholinergic Fibers, Cognition, Dopamine, Humans, Neural Pathways, Norepinephrine, Serotonin, Prefrontal Cortex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review