GFAP in health and disease

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Oxidative Stress, Caloric Restriction, and Aging

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Localization of neuronal and glial glutamate transporters

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Molecular profile of reactive astrocytes—Implications for their role in neurologic disease

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Glial Fibrillary Acidic Protein: GFAP-Thirty-One Years (1969–2000)

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Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration

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An acidic protein isolated from fibrous astrocytes

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

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Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.

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Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage

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The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer

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Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.

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Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

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Intermediate Filaments: A Chemically Heterogeneous, Developmentally Regulated Class of Proteins

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GFAP and Astrogliosis

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The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease

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Alzheimer’s disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules

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Radial glia give rise to adult neural stem cells in the subventricular zone

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Non–cell autonomous effect of glia on motor neurons in an embryonic stem cell–based ALS model

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Integrated Brain Circuits: Astrocytic Networks Modulate Neuronal Activity and Behavior

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Characterization of CNS Precursor Subtypes and Radial Glia

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Astrocytes Potentiate Transmitter Release at Single Hippocampal Synapses

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Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease

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Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

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hGFAP‐cre transgenic mice for manipulation of glial and neuronal function in vivo

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Dividing Precursor Cells of the Embryonic Cortical Ventricular Zone Have Morphological and Molecular Characteristics of Radial Glia

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Hypocretin (orexin) cell loss in Parkinson's disease

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Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients

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Cellular composition and cytoarchitecture of the adult human subventricular zone: A niche of neural stem cells

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GFAP Is Necessary for the Integrity of CNS White Matter Architecture and Long-Term Maintenance of Myelination

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Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin

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Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder

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GFAP promoter directs astrocyte-specific expression in transgenic mice

Brenner, M., Kisseberth, W., Su, Y., Besnard, F., & Messing, A. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01030.1994 · Cited by 485

Impaired mechanical stability, migration and contractile capacity in vimentin deficient fibroblasts

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Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group.

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Glutathione peroxidase, glial cells and Parkinson's disease

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Glial pathology but absence of apoptotic nigral neurons in long‐standing Parkinson's disease

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GFAP promoter elements required for region‐specific and astrocyte‐specific expression

Lee, Y., Messing, A., Su, M., & Brenner, M. (2008) · Glia · doi:10.1002/glia.20622 · Cited by 424

Chaperone activity of alpha‐crystallins modulates intermediate filament assembly.

Nicholl, I. D., & Quinlan, R. A. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06339.x · Cited by 423

Astrocyte intermediate filaments in CNS pathologies and regeneration

Pekny, M., & Pekna, M. (2004) · The Journal of Pathology · doi:10.1002/path.1645 · Cited by 420

GFAP mRNA increases with age in rat and human brain

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Deficient Cerebellar Long-Term Depression, Impaired Eyeblink Conditioning, and Normal Motor Coordination in GFAP Mutant Mice

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Release of Glial Tissue–Specific Proteins After Acute Stroke

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Postnatal Development of Radial Glia and the Ventricular Zone (VZ): a Continuum of the Neural Stem Cell Compartment

Tramontin, A. D. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.6.580 · Cited by 386

The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases

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Astrocyte phenotype in relation to Alzheimer‐type pathology in the ageing brain

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Intermediate filament interactions can be altered by HSP27 and αB-crystallin

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Intermediate Filament Protein Partnership in Astrocytes

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Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology.

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Structure and Assembly Properties of the Intermediate Filament Protein Vimentin: The Role of its Head, Rod and Tail Domains

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Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments.

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Glial fibrillary acidic protein immunoreactivity in the prefrontal cortex distinguishes younger from older adults in major depressive disorder

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Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat

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Patterns of gliosis in alzheimer's disease and aging cerebrum

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Mice lacking glial fibrillary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally.

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PROGRESSIVE FIBRINOID DEGENERATION OF FIBRILLARY ASTROCYTES ASSOCIATED WITH MENTAL RETARDATION IN A HYDROCEPHALIC INFANT

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Age-Dependent Reductions in the Level of Glial Fibrillary Acidic Protein in the Prefrontal Cortex in Major Depression

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Chaperone-mediated autophagy: selectivity pays off

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A sensitive ELISA for glial fibrillary acidic protein: application in CSF of adults

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Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions

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Changes in brain gene expression shared by scrapie and Alzheimer disease.

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Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments

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Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus

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Glial fibrillary acidic protein is elevated in superior frontal, parietal and cerebellar cortices of autistic subjects

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Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice.

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Suppression by antisense mRNA demonstrates a requirement for the glial fibrillary acidic protein in the formation of stable astrocytic processes in response to neurons.

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Identification of Regulators of Chaperone-Mediated Autophagy

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Serum GFAP is a diagnostic marker for glioblastoma multiforme

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Circulating autoantibodies to neuronal and glial filament proteins in autism

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Glial Fibrillary Acidic Protein: Regulation by Hormones, Cytokines, and Growth Factors

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Radial glial cells as neuronal precursors: a new perspective on the correlation of morphology and lineage restriction in the developing cerebral cortex of mice

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Molecular identity, distribution and heterogeneity of glial fibrillary acidic protein: an immunoblotting and immunohistochemical study of Schwann cells, satellite cells, enteric glia and astrocytes

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Phosphorylation of human keratin 18 serine 33 regulates binding to 14‐3‐3 proteins

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Molecular cloning and primary structure of human glial fibrillary acidic protein.

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Determination of S-100 and glial fibrillary acidic protein concentrations in cerebrospinal fluid after brain infarction.

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GFAP and its role in Alexander disease

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An Alternative Splicing Product of the Lamin A/C Gene Lacks Exon 10

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Brain injury in a dish: a model for reactive gliosis

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Development of cerebellar astroglia: Transitions in form and cytoskeletal content

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General and dramatic glial reaction in Alzheimer brains

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Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage

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The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction

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Cellular organization of the central canal ependymal zone, a niche of latent neural stem cells in the adult mammalian spinal cord

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Inactivation of the Glial Fibrillary Acidic Protein Gene, But Not That of Vimentin, Improves Neuronal Survival and Neurite Growth by Modifying Adhesion Molecule Expression

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Neurons, glia, and plasticity in normal brain aging.

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Assembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunit.

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Age-related changes in glial fibrillary acidic protein mRNA in the mouse brain

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Alexander Disease-Associated Glial Fibrillary Acidic Protein Mutations in Mice Induce Rosenthal Fiber Formation and a White Matter Stress Response

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Cytoskeleton and Vesicle Mobility in Astrocytes

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Glutamate receptor agonists up-regulate glutamate transporter GLAST in astrocytes

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Reactive Astrogliosis is Widespread in the Subcortical White Matter of Amyotrophic Lateral Sclerosis Brain

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