Cited by 110Functional Brain Connectivity StudiesSuicide and Self-Harm StudiesTreatment of Major Depression

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Resting-state functional connectivity of the amygdala in suicide attempters with major depressive disorder

Kang, Seung-Gul, Na, Kyoung-Sae, Choi, Jae-Won, Kim, Jeong-Hee, Son, Young-Don, Lee, Yu Jin·2017·Progress in Neuro-Psychopharmacology and Biological Psychiatry

DOI 10.1016/j.pnpbp.2017.04.029

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Abstract

In this study, we investigated the difference in resting-state functional connectivity (RSFC) of the amygdala between suicide attempters and non-suicide attempters with major depressive disorder (MDD) using functional magnetic resonance imaging (fMRI). This study included 19 suicide attempters with MDD and 19 non-suicide attempters with MDD. RSFC was compared between the two groups and the regression analyses were conducted to identify the correlation between RSFC and Scale for Suicide Ideation (SSI) scores in the suicide attempt group. Statistical significance was set at p-value (uncorrected) <0.005 with k≥28 voxels. Compared with non-suicide attempters, suicide attempters showed significantly increased RSFC of the left amygdala with the right insula and left superior orbitofrontal area, and increased RSFC of the right amygdala with the left middle temporal area. The regression analysis showed a significant correlation between the SSI total score and RSFC of the right amygdala with the right parahippocampal area in the suicide attempt group. The present RSFC findings provide evidence of a functional neural basis and will help reveal the pathophysiology underlying suicidality in subjects with MDD.

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Abnormal regional homogeneity in young adult suicide attempters with no diagnosable psychiatric disorder: A resting state functional magnetic imaging study
Cao, J., Chen, J.-M., Kuang, L., Ai, M., Fang, W.-D., Gan, Y., Wang, W., Chen, X.-R., Xu, X.-M., Wang, H.-G., et al. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2014.10.011 · Cited by 64
Altered brain processing of decision-making in healthy first-degree biological relatives of suicide completers
Ding, Y., Pereira, F., Hoehne, A., Beaulieu, M.-M., Lepage, M., Turecki, G., & Jollant, F. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.221 · Cited by 55
Self-report depressive symptoms do not directly predict suicidality in nonclinical individuals: Contributions toward a more psychosocial approach to suicide risk
Campos, R. C., Holden, R. R., Laranjeira, P., Troister, T., Oliveira, A. R., Costa, F., Abreu, M., & Fresca, N. (2016) · Death Studies · doi:10.1080/07481187.2016.1150920 · Cited by 41
Understanding Suicidal Behavior: The Contribution of Recent Resting-State fMRI Techniques
Serafini, G., Pardini, M., Pompili, M., Girardi, P., & Amore, M. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00069 · Cited by 29
Scale for Suicide Ideation: Psychometric properties of a self-report version
Beck, A. T., Steer, R. A., & Ranieri, W. F. (1988) · Journal of Clinical Psychology · doi:10.1002/1097-4679(198807)44:4

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Authors: Kang, S.-G., Na, K.-S., Choi, J.-W., Kim, J.-H., Son, Y.-D., & Lee, Y. J.
Affiliations: Gachon University (KR)
Eulji University (KR)
Korea University (KR)
Seoul National University (KR)
Corresponding author: Son, Young-Don
Lee, Yu Jin
ORCID: Kang, Seung-Gul
Na, Kyoung-Sae
Choi, Jae-Won
Son, Young-Don
Lee, Yu Jin
Venue: Progress in Neuro-Psychopharmacology and Biological Psychiatry
Publisher: Elsevier BV
Published: 2017-07
Volume: 77
Pages: 222-227
ISSN: 0278-5846 (ISSN-L)
DOI: 10.1016/j.pnpbp.2017.04.029
OpenAlex: W2605816761
Cited by: 110
References: 48
Citations by year: 2026: 7 · 2025: 8 · 2024: 9 · 2023: 14 · 2022: 13 · 2021: 15 · 2020: 16 · 2019: 15 · 2018: 12 · 2017: 1
FWCI: 6.91
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Progress in Neuro-Psychopharmacology and Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: Ministry of Education, Science and Technology
National Research Foundation of Korea (2012R1A1A1043599)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords: resting-state functional connectivity, amygdala, suicide attempters, major depressive disorder, suicidal ideation, insula, middle temporal cortex, parahippocampal cortex, depression pathophysiology
MeSH terms: Amygdala, Brain, Major Depressive Disorder, Humans, Magnetic Resonance Imaging, Neural Pathways, Rest, Suicide, Attempted, Case-Control Studies, Functional Neuroimaging

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Resting-state functional connectivity of the amygdala in suicide attempters with major depressive disorder

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