Structural and functional alterations of the suicidal brain: An updated review of neuroimaging studies
Abstract
Brain imaging is a non-invasive and in vivo direct estimation of detailed brain structure, regional brain functioning and estimation of molecular processes in the brain. The main objective of this review was to analyze functional and structural neuroimaging studies of individuals at risk for suicide. We reviewed articles published between 2005 and 2018, indexed in PubMed and Medline, assessing structural and functional alterations of the brain of individuals at high risk for suicide and at low risk for suicide. We reviewed functional and structural neuroimaging studies which included individuals with a history of suicidal ideation or attempt in major depressive disorder (MDD), bipolar disorder (BD), psychosis, and borderline personality disorder (BPD). We selected 45 papers that focused on suicidality in MDD, 17 papers on BD, 11 papers on psychosis, and 5 papers on BPD. The suicidal brain across psychiatric diagnoses seems to heavily involve dysfunction of the fronto-temporal network, primarily involving reductions of gray and white matter volumes in the pre-frontal cortex (PFC), anterior cingulate, and superior temporal gyrus. Nonetheless, there are several ways to define suicidal behaviour and ideation. Therefore, it still remains difficult to combine the evidence from imaging studies that used different definitions of suicidality.
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Prior reviews have identified brain regions implicated in suicidal and non-suicidal behaviors.
“Several prior reviews have highlighted brain regions implicated in suicidal (32, 45–49) and non-suicidal behaviors (39, 50).”
From Neural correlates associated with suicide and nonsuicidal self-injury in youth (2021) · cites this paper as [46]
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Understanding the Complex of Suicide in Depression: from Research to Clinics
Orsolini, L., Latini, R., Pompili, M., Serafini, G., Volpe, U., Vellante, F., Fornaro, M., Valchera, A., Tomasetti, C., Fraticelli, S., et al. (2020) · Psychiatry Investigation · doi:10.30773/pi.2019.0171 · Cited by 373 · see citing works
Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies
Schmaal, L., van Harmelen, A.-L., Chatzi, V., Lippard, E. T. C., Toenders, Y. J., Averill, L. A., Mazure, C. M., & Blumberg, H. P. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0587-x · Cited by 373 · see citing works
Schmaal, L., Pozzi, E., Ho, T. C., van Velzen, L. S., Veer, I. M., Opel, N., Someren, E. J. W. V., Han, L. K. M., Aftanas, L., Aleman, A., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0842-6 · Cited by 246 · see citing works
Neural correlates associated with suicide and nonsuicidal self-injury in youth
Auerbach, R. P., Pagliaccio, D., Allison, G. O., Alqueza, K. L., & Alonso, M. F. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.06.002 · Cited by 204 · see citing works
Neuroimaging the consciousness of self: Review, and conceptual-methodological framework
Frewen, P., Schroeter, M. L., Riva, G., Cipresso, P., Fairfield, B., Padulo, C., Kemp, A. H., Palaniyappan, L. K., Owolabi, M. O., Kusi‐Mensah, K., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.01.023 · Cited by 177 · see citing works
“Moreover, the authors found altered RSFC in the PCC, PRC, MPFC, and temporoparietal areas to be associated with suicide risk, all ROIs considered herein to primarily underlie V-SRP (Bani-Fatemi et al., 2018).”
Hong, S., Liu, Y. S., Cao, B., Cao, J., Ai, M., Chen, J., Greenshaw, A. J., & Kuang, L. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.10.077 · Cited by 68 · see citing works
Parvalbumin interneuron alterations in stress-related mood disorders: A systematic review
Perlman, G., Tanti, A., & Mechawar, N. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100380 · Cited by 65 · see citing works
Cao, J., Ai, M., Chen, X., Chen, J., Wang, W., & Kuang, L. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2019.112713 · Cited by 48 · see citing works
Johnston, J. N., Campbell, D., Caruncho, H. J., Henter, I. D., Ballard, E. D., & Zarate, C. A. (2021) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyab083 · Cited by 50 · see citing works
Vidal-Ribas, P., Janiri, D., Doucet, G. E., Pornpattananangkul, N., Nielson, D. M., Frangou, S., & Stringaris, A. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20020120 · Cited by 45 · see citing works
Qiao, D., Zhang, A., Sun, N., Yang, C., Jian-ying, L., Zhao, T., Wang, Y., Xu, Y., Wen, Y., Zhang, K., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.608197 · Cited by 41 · see citing works
“Although there are few studies on the role of instability of FC of STG in SI, previous studies investigating morphological and functional abnormalities of brain in patients with SI have reported altered STG connections and gray volumes (46, 47).”
ResultWei, S., Womer, F. Y., Edmiston, E. K., Zhang, R., Jiang, X., Wu, F., Kong, L., Zhou, Y., Tang, Y., & Wang, F. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109827 · Cited by 41 · see citing works
Kang, S., Cho, S., Na, K., Lee, J. S., Joo, S. W., Cho, S., Son, Y., & Lee, Y. J. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111032 · Cited by 35 · see citing works
Yang, Y., Chattun, M. R., Yan, R., Zhao, K., Chen, Y., Zhu, R., Shi, J., Wang, X., Lu, Q., & Yao, Z. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00206-4 · Cited by 35 · see citing works
How Does COVID-19 Affect the Neurobiology of Suicide?
Conejero, I., Nobile, B., Olié, É., & Courtet, P. (2021) · Current Psychiatry Reports · doi:10.1007/s11920-021-01227-x · Cited by 85 · see citing works
Vieira, R., Faria, A. R., Ribeiro, D., Picó‐Pérez, M., & Bessa, J. M. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110799 · Cited by 34 · see citing works
Dobbertin, M. D., Blair, K. S., Carollo, E., Blair, J., Dominguez, A. J., & Bajaj, S. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1083244 · Cited by 31 · see citing works
Zhu, R., Tian, S., Wang, H., Jiang, H., Wang, X., Shao, J., Wang, Q., Yan, R., Tao, S., Liu, H., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.597770 · Cited by 30 · see citing works
“Recent fMRI studies have shown that psychiatric disorders with suicide attempts are linked to structural and functional abnormalities in distinct brain networks, especially the frontolimbic system (14).”
BackgroundCao, J., Chen, X., Chen, J., Ai, M., Gan, Y., He, J., & Kuang, L. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.567976 · Cited by 29 · see citing works
Tian, S., Zhu, R., Chattun, M. R., Wang, H., Chen, Z., Zhang, S., Shao, J., Wang, X., Yao, Z., & Lü, Q. (2021) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00448-7 · Cited by 28 · see citing works
Zheng, M., Da, H., Pan, X., Bian, Y., Li, X., Xiao, Q., Qiu, M., Xiang, N., Dongmei, Z., Wei, Q., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.01.115 · Cited by 27 · see citing works
Wáng, Q., He, C., Wang, Z., Fan, D., Zhang, Z., Xie, C., Yan, C., Chen, X., Li, L., Castellanos, F. X., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02655-4 · Cited by 26 · see citing works
Gong, J., Chen, G., Zhou, M., Jia, Y., Zhong, S., Chen, F., Lai, S., Luo, Z., Wang, J., Xu, H., et al. (2020) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867420948960 · Cited by 25 · see citing works
“A previous functional magnetic resonance imaging (fMRI) study on MDD found greater amplitude of lowfrequency fluctuations (ALFF) in the right superior temporal gyrus (STG) in MDD with SA compared to without SA and healthy controls (HCs) (Fan et al., 2013).”
BackgroundInfluentialLi, Q., Dong, F., Gai, Q., Che, K., Ma, H., Zhao, F., Chu, T., Mao, N., & Wang, P. (2023) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.28650 · Cited by 24 · see citing works
“13 The reason may be that there is time fl ow between brain regions, which provides rich dynamic brain network information for diagnosing MDD.”
BackgroundInfluentialCaudothalamic dysfunction in drug-free suicidally depressed patients: an MEG study
Chattun, M. R., Zhang, S., Chen, Y. S., Wang, Q., Amdanee, N., Tian, S., Lü, Q., & Yao, Z. (2018) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-018-0968-1 · Cited by 24 · see citing works
Zhao, P., Wang, X., Wang, Q., Yan, R., Chattun, M. R., Yao, Z., & Lü, Q. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05364-w · Cited by 24 · see citing works
Canal‐Rivero, M., Tordesillas‐Gutiérrez, D., Ruíz-Veguilla, M., de la Foz, V. O., Cuevas‐Esteban, J., de Lucas, E. M., Vázquez-Bourgón, J., Ayesa‐Arriola, R., & Crespo‐Facorro, B. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.109948 · Cited by 21 · see citing works
Alteration of single‐subject gray matter networks in major depressed patients with suicidality
Li, H., Yang, J., Yin, L., Zhang, H., Zhang, F., Chen, Z., Jia, Z., & Gong, Q. (2020) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.27499 · Cited by 22 · see citing works
“Patients with depression and suicidality (SU) included both suicidal attempters (SA; patients with depression and a history of suicidal behavior) and suicidal ideators (SI; patients with depression who had a strong intent to die).(2) The Barratt Impulsiveness Scale (BIS) was applied only to the SU group.”
BackgroundMethodInfluentialGoldstein, T., & Franzen, P. (2022) · Current Sleep Medicine Reports · doi:10.1007/s40675-022-00222-9 · Cited by 27 · see citing works
Yi, Z., Xia, L., Yi, J., Jia, Y., Wei, L., Shen, S., Wu, N., Wang, D., Zhou, H., Li, X., et al. (2025) · Psychological Medicine · doi:10.1017/s0033291724003283 · Cited by 20 · see citing works
“Reduced gray matter volume (GMV) of the ACC has been found in suicide attempters among individuals with various psychiatric disorders (Bani-Fatemi et al., 2018).”
Dusi, N., Bracco, L., Bressi, C., Delvecchio, G., & Brambilla, P. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.08.074 · Cited by 19 · see citing works
Dimick, M. K., Hird, M. A., Sultan, A. A., Mitchell, R. H. B., Sinyor, M., MacIntosh, B. J., & Goldstein, B. I. (2022) · Psychological Medicine · doi:10.1017/s0033291721005419 · Cited by 17 · see citing works
“Furthermore, increased frontal pole volume predicted suicide attempts in a sample of females with BD (Bani-Fatemi et al., 2018).”
Dai, Z., Zhang, S., Wang, H., Chen, Z., Zhang, W., Hu, X., Yao, Z., & Lü, Q. (2022) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13487 · Cited by 17 · see citing works
White Matter Network Disruption Is Associated With Melancholic Features in Major Depressive Disorder
He, M., Cheng, Y., Chu, Z., Wang, X., Xu, J., Lü, Y., Shen, Z., & Xu, X. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.816191 · Cited by 16 · see citing works
“A series of studies have suggested changes in brain function and structure in patients with MDD (7, 8), such as interruption of functional homogeneity and decreased effective connectivity of cortical regions involved in emotion regulation (9).”
BackgroundShaffer, J. J., Willour, V. L., Fiedorowicz, J. G., Christensen, G. E., Long, J. D., Johnson, C. P., Schmitz, S. L., Williams, A. J., Wemmie, J. A., & Magnotta, V. A. (2021) · Brain Imaging and Behavior · doi:10.1007/s11682-021-00552-2 · Cited by 16 · see citing works
“, a majority of imaging studies that have explored suicide attempt or ideation in psychiatric patient populations have focused on major depression with significantly fewer studies in BD (Bani-Fatemi et al., 2018) even though the prevalence is 2–3 821 Brain Imaging and Behavior (2022) 16:820–833”
Backgroundde Winter, R. F. P., Meijer, C. M., Enterman, J. H., Kool-Goudzwaard, N., Gemen, M., van den Bos, A. T., Steentjes, D., van Son, G. E., Hazewinkel, M. C., Beurs, D. P. D., et al. (2023) · JMIR Research Protocols · doi:10.2196/45438 · Cited by 13 · see citing works
“Scientific knowledge, such as theoretical concepts derived from neuroimaging and research into genetic vulnerability for suicide, will be difficult to apply in clinical practice [8,9], as science has not been able to distinguish different kinds of suicidality or pinpoint drivers or etiology.”
Feng, S., Zhou, S., Huang, Y., Peng, R., Han, R., Li, H., Yi, Y., Feng, Y., Ning, Y., Han, W., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.10.031 · Cited by 15 · see citing works
He, M., Ping, L., Chu, Z., Zeng, C., Shen, Z., & Xu, X. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.856366 · Cited by 14 · see citing works
“, 2016), it is generally believed that SI is related to abnormal neural network connectivity and not limited to a single brain region (Chase et al., 2017; Bani-Fatemi et al., 2018; Schmaal et al., 2020).”
BackgroundBomyea, J. A., Stout, D. M., & Simmons, A. N. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.07.050 · Cited by 14 · see citing works
Chen, M., Li, X., Zhuang, W., Xu, Y., Pei, Z., Liu, J., Zhang, Y., Yu, C., Wang, Y., Liu, X., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03515-z · Cited by 15 · see citing works
“Thefactors underlying suicidal ideation are multifaceted and complex, involving disruptions in brain networks related to emotional regulation, impulse control, and decision-making [6].”
Zhang, S., Vladimir Litvak, A., Tian, S., Dai, Z., Tang, H., Wang, X., Yao, Z., & Lü, Q. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-021-01371-8 · Cited by 13 · see citing works
Vandeloo, K. L., Burhunduli, P., Sylvain Bouix, A., Owsia, K., Cho, K. I. K., Fang, Z., Geel, A. V., Pasternak, O., Blier, P., & Phillips, J. L. (2022) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2022.12.007 · Cited by 12 · see citing works
“Previous magnetic resonance imaging (MRI) studies have identified both regional and whole-brain differences in patients with and without suicide attempt history (9), such as reduced structural gray matter volume and abnormal fronto-thalamo-limbic functional connectivity (10,11).”
BackgroundYohannes, K., Gezahegn, M., Aregu, M. B., Simachew, Y., Moges, A., Ayano, G., Toitole, K. K., Mokona, H., & Abebe, L. (2023) · BMC Psychology · doi:10.1186/s40359-023-01162-x · Cited by 11 · see citing works
Wen, X., Zhang, J.-H., Wei, G., Wu, M.-L., Zhang, Y., Zhang, Q., & Hou, G.-Q. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.10.009 · Cited by 10 · see citing works
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Kamimura, H., Matsuoka, T., Okai, H., Shimizu, N., Harada, S., & Matsuo, K. (2022) · Scientific Reports · doi:10.1038/s41598-022-22345-3 · Cited by 10 · see citing works
Resting State EEG Correlates of Suicide Ideation and Suicide Attempt
Amico, F., Frye, R. E., Shannon, S. M., & Rondeau, S. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13060884 · Cited by 10 · see citing works
Cattarinussi, G., Delvecchio, G., Prunas, C., Moltrasio, C., & Brambilla, P. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.03.088 · Cited by 10 · see citing works
Davey, D. K., Jurick, S. M., Crocker, L. D., Hoffman, S. N., Sanderson‐Cimino, M. E., Tate, D. F., Velez, C. S., Delano‐Wood, L., & Jak, A. J. (2021) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2021.111389 · Cited by 10 · see citing works
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Treatment response with ketamine in chronic suicidality: An open label functional connectivity study
Can, A., Hermens, D. F., Mohamed, A. Z., Shan, Z., Dutton, M., Gallay, C. C., Forsyth, G., Jamieson, D., & Lagopoulos, J. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.03.064 · Cited by 10 · see citing works
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Chen, V. C., Kao, C. C., Tsai, Y., McIntyre, R. S., & Weng, J. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11030174 · Cited by 8 · see citing works
“However, network alterations in the brain are important factors for patients with depression as well as suicidal ideation and may be linked to the risk of suicide attempts [13].”
BackgroundHuang, M., Kuan, Y., Tu, P., Chang, W., Chan, Y. E., & Su, T. (2025) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13786 · Cited by 7 · see citing works
“Structurally, increased frontal pole volume has been predictive of suicide attempts in females with BD [47].”
Khalil, M. H. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1524531 · Cited by 7 · see citing works
Lee, D. Y., Byeon, G., Kim, N., Son, S. J., Park, R. W., & Park, B. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02989-7 · Cited by 6 · see citing works
The Role of Frontolimbic Network in Suicide: A Descriptive Literature Review of Neuroimaging Studies
Shen, Y., Zhu, J., & Yu, Y. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.10.035 · Cited by 7 · see citing works
Goldstein, K. E., Pietrzak, R. H., Challman, K. N., Chu, K.-W., Beck, K. D., Brenner, L. A., Interian, A., Myers, C. E., Shafritz, K. M., Szeszko, P. R., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.09.149 · Cited by 7 · see citing works
ELECTROPHYSIOLOGICAL CORRELATES OF SUICIDALITY
Rakús, T., Hubčíková, K., Bruncvik, L., Pechanova, Z., & Brunovský, M. (2021) · Psychiatria Danubina · doi:10.24869/psyd.2021.266 · Cited by 6 · see citing works
Delayed prefrontal hemodynamic response associated with suicide risk in autism spectrum disorder
Ota, T., Iida, J., Okazaki, K., Ishida, R., Takahashi, M., Okamura, K., Yamamuro, K., Kishimoto, N., Kimoto, S., Yasuda, Y., et al. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.112971 · Cited by 6 · see citing works
Daneshmand, M., Kashefizadeh, M., Soleimani, M., Mirzaei, S., & Tayim, N. (2024) · Acta Diabetologica · doi:10.1007/s00592-024-02234-z · Cited by 5 · see citing works
“Understanding the intricate relationship between the prefrontal cortex's executive functions and suicidal ideation can provide valuable insights into the underlying cognitive mechanisms involved in the development and maintenance of suicidal tendencies [61, 62].”
Pharmacological Strategies for Suicide Prevention Based on the Social Pain Model: A Scoping Review
Rajkumar, R. P. (2022) · Psych · doi:10.3390/psych4030038 · Cited by 5 · see citing works
“Instead, functional imaging studies have revealed evidence of reduced activity in the prefrontal cortices, left insula and right putamen, possibly related to altered serotonergic transmission, and increased activity in the superior and middle temporal gyri and right occipital cortex [16,17].”
BackgroundInfusing Hope Into the Treatment of Suicidality: a Review of Ketamine’s Effects on Suicidality
Rengasamy, M. L., Hsiung, K. S., & Price, R. B. (2019) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-019-00184-3 · Cited by 5 · see citing works
“, caudate), while fMRI studies tend to identify resting-state activity reductions in similar regions with varying changes in response to certain tasks [84, 85].”
BackgroundMultimodal neuroimaging and suicidality in a US population-based sample of school-aged childrenPreprint
Vidal‐Ribas, P., Janiri, D., Doucet, G. E., Pornpattananangkul, N., Nielson, D. M., Frangou, S., & Stringaris, A. K. (2019) · medRxiv · doi:10.1101/19013193 · Cited by 5 · see citing works
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Chase, H. W., Segreti, A. M., Fournier, J. C. J., Phillips, M. L., Brent, D. A., & Pan, L. A. (2019) · Journal of Medical Psychology · doi:10.3233/jmp-180018 · Cited by 4 · see citing works
Bohaterewicz, B., Sobczak, A. M., Krześniak, A., Mętel, D., & Adamczyk, P. (2021) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2021.111343 · Cited by 4 · see citing works
The prospect of suicide biomarkers: from neurobiology to precision prevention
Ren, N., Zheng, S., Zhou, Y., Zhang, X., Wang, M. H., & Bian, Y. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1757838 · Cited by 3 · see citing works
Ishikawa, K., Nemoto, K., Shiratori, Y., Sodeyama, N., Kodama, K., Usuniwa, H., Yamada, N., Yaguchi, C., Hori, T., Arai, T., et al. (2022) · Psychiatry and Clinical Neurosciences Reports · doi:10.1002/pcn5.35 · Cited by 3 · see citing works
“5,6 A previous study using structural magnetic resonance imaging (MRI) suggested that suicide attempters (SAs) with depression showed volume reduction or cortical thinning in frontal regions, such as ventral lateral prefrontal cortex, dorso-lateral prefrontal cortex (DLPFC), and orbitofrontal…”
BackgroundSerum Fatty Acid Latent Classes Are Associated With Suicide in a Large Military Personnel Sample
Ryan, A. T., Postolache, T. T., Taub, D. D., Wilcox, H. C., Ghahramanlou‐Holloway, M., Umhau, J. C., & Deuster, P. A. (2021) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.20m13275 · Cited by 3 · see citing works
Electroretinography and suicidal behaviors: a systematic review
Kaggwa, M. M., Prat, S. S., Davids, A., Robbins, A., Erb, B., Mамак, М., Chaimowitz, G. A., & Olagunju, A. T. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05453-w · Cited by 3 · see citing works
“An extended photopic on-off protocol for ERG has been used to assess retina function in studies analyzing psychiatric conditions [9].”
BackgroundMethodCanal‐Rivero, M., Tordesillas‐Gutiérrez, D., Ruíz-Veguilla, M., de la Foz, V. O., de Lucas, E. M., Romero-García, R., Vázquez-Bourgón, J., Ayesa‐Arriola, R., & Crespo‐Facorro, B. (2025) · Archives of Suicide Research · doi:10.1080/13811118.2025.2454581 · Cited by 2 · see citing works
“The STG plays a key role in social cognition (Bani-Fatemi et al., 2018), and structural abnormalities in this region have been observed in individuals with social functioning deficits (Goldstein et al., 2009).”
Torino, G., Maggioni, E., Lengvenytė, A., Brambilla, P., & Delvecchio, G. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03626-7 · Cited by 2 · see citing works
Xia, L., Wu, N., Wang, D., Zhou, H., & Zhang, X. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03784-8 · Cited by 3 · see citing works
“Reduced grey matter volume (GMV) of the ACC has also been found in patients with psychiatric disorders who have attempted suicide [24].”
Dai, Z., Jia, M., Zhou, H., & Wang, H. (2026) · Translational Psychiatry · doi:10.1038/s41398-025-03800-x · Cited by 2 · see citing works
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Morphofunctional changes in the neuronal environment in suicide
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Neuroanatomical signatures of suicide attempts in major depressive disorder
Kim, A., Kang, Y., Kang, J. C., & Ham, B. (2026) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2026.112192 · Cited by 1 · see citing works
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Pharmacological and Neuromodulatory Treatments for Suicidality: A 2026 Updated Review
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Park, Y.-M. (2023) · Chronobiology in Medicine · doi:10.33069/cim.2023.0009 · Cited by 1 · see citing works
“a well-known characteristic of depression and suicidal tendencies [23].”
BackgroundCognitive dysfunction: An important feature of major depressive disorder
Duan, D.-X., Li, X., Yang, L., Wang, W., & Zhu, H. (2023) · Neurons and Neurological Disorders · doi:10.58489/2836-8851/011 · Cited by 1 · see citing works
Feedback Processing as it Relates to Suicidal Ideation and Behavior Using a Time-Frequency ApproachPreprint
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Candidate Genes for Suicide Risk in Head and Neck Squamous Cell Carcinoma Patients
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- Authors
- Bani-Fatemi, A., Tasmim, S., Graff-Guerrero, A., Gerretsen, P., Strauss, J., Kolla, N., Spalletta, G., & De Luca, V.
- Affiliations
- Centre for Addiction and Mental Health (CA)
- University of Toronto (CA)
- Baylor College of Medicine (US)
- Venue
- Psychiatry Research Neuroimaging
- Publisher
- Elsevier BV
- Published
- 2018-08
- Volume
- 278
- Pages
- 77-91
- ISSN
- 0925-4927 (ISSN-L)
- OpenAlex
- W2803650243
- Cited by
- 112
- References
- 87
- Citations by year
- 2026: 13 · 2025: 14 · 2024: 7 · 2023: 22 · 2022: 15 · 2021: 15 · 2020: 15 · 2019: 10 · 2018: 1
- FWCI
- 1.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research Neuroimaging (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- suicide, suicidal ideation, suicide attempts, brain structure, brain function, major depressive disorder, bipolar disorder, psychosis, borderline personality disorder, fronto-temporal network, prefrontal cortex, anterior cingulate cortex, superior temporal gyrus, gray matter volume, white matter volume
- MeSH terms
- Bipolar Disorder, Borderline Personality Disorder, Brain, Major Depressive Disorder, Humans, Magnetic Resonance Imaging, Suicidal Ideation, Neuroimaging, White Matter
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