Functional connectivity of the human amygdala using resting state fMRI
Open accessAbstract
The amygdala is composed of structurally and functionally distinct nuclei that contribute to the processing of emotion through interactions with other subcortical and cortical structures. While these circuits have been studied extensively in animals, human neuroimaging investigations of amygdala-based networks have typically considered the amygdala as a single structure, which likely masks contributions of individual amygdala subdivisions. The present study uses resting state functional magnetic resonance imaging (fMRI) to test whether distinct functional connectivity patterns, like those observed in animal studies, can be detected across three amygdala subdivisions: laterobasal, centromedial, and superficial. In a sample of 65 healthy adults, voxelwise regression analyses demonstrated positively-predicted ventral and negatively-predicted dorsal networks associated with the total amygdala, consistent with previous animal and human studies. Investigation of individual amygdala subdivisions revealed distinct differences in connectivity patterns within the amygdala and throughout the brain. Spontaneous activity in the laterobasal subdivision predicted activity in temporal and frontal regions, while activity in the centromedial nuclei predicted activity primarily in striatum. Activity in the superficial subdivision positively predicted activity throughout the limbic lobe. These findings suggest that resting state fMRI can be used to investigate human amygdala networks at a greater level of detail than previously appreciated, allowing for the further advancement of translational models.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Negative functional connectivity, reflecting network segregation and specialization, has been found between amygdala sub-regions and more dorsal and posterior brain regions in adults and in a cross-sectional sample from childhood to early adulthood.
“Negative functional connectivity, or segregation and specialization of networks (Rubinov and Sporns, 2010), has been observed between amygdalar sub-regions and more dorsal and posterior brain regions in both adults (Roy et al., 2009) and in a cross-sectional sample spanning childhood and early adulthood (Gabard-Durnam et al., 2014).”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Roy et al., 2009
Earlier studies have reported that connectivity between the medial prefrontal cortex and all amygdala sub-regions increases with age.
“Previous research has shown coupling of mPFC and all amygdala sub-regions with increasing age (Roy et al., 2009, Qin et al., 2012, Gabard-Durnam et al., 2014),”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Roy et al., 2009
The observed pattern of decreased parieto-occipital connectivity and increased medial prefrontal connectivity matches adult resting-state functional connectivity patterns of amygdala sub-regions.
“which corresponds with adult RSFC patterns of amygdala sub-regions (Roy et al., 2009, Qin et al., 2012, Gabard-Durnam et al., 2014), albeit with varying effects by sex.”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Roy et al., 2009
Prior research has identified distinct resting-state functional connectivity patterns across amygdalar nuclei, with age-related positive connectivity to ventromedial prefrontal, temporal, and subcortical regions and negative connectivity to parietal and occipital cortices.
“Previous work has found distinct functional connectivity patterns, as measured with RSFC, across amygdalar nuclei (Roy et al., 2009, Li et al., 2012, Qin et al., 2012, Gabard-Durnam et al., 2014), specifically different patterns of age-dependent positive connectivity between amygdalar nuclei and ventromedial PFC (vmPFC), temporal, and subcortical regions, as well as negative connectivity with pari”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Roy et al., 2009
Resting-state functional connectivity analyses did not use left or right centromedial amygdala seed regions, limiting direct comparison with existing amygdala sub-region studies.
“As such, RSFC analyses were not conducted with either left or right CMA seed regions, which limits direct comparisons with existing amygdala sub-region RSFC studies (Roy et al., 2009, Li et al., 2012, Qin et al., 2012, Gabard-Durnam et al., 2014).”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Roy et al., 2009
If decoupling between the superficial amygdala and parieto-occipital cortices is the adult norm, then the sex-specific trajectories of amygdala sub-region connectivity seen in this adolescent sample may shift toward mature adult patterns.
“If decoupling of SFA and parieto-occipital cortices is indeed the norm in adulthood as some studies suggest (Roy et al., 2009, Gabard-Durnam et al., 2014), then the sexually dimorphic trajectories of amygdala sub-regional connectivity observed in the current sample may give way to mature patterns observed in adults;”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Roy et al., 2009
The comparable functional coupling patterns in both sexes are in accordance with a healthy developmental trajectory.
“which is in accordance with a healthy developmental trajectory (Roy et al., 2009, Qin et al., 2012, Gabard-Durnam et al., 2014).”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Roy et al., 2009
Roy and colleagues reported functional connectivity of the amygdala with ventral medial prefrontal regions, insula, thalamus and striatum at rest and anticorrelations with the dorsal ACC, superior frontal gyrus, bilateral middle frontal gyrus and posterior cingulate cortex.
“Roy and colleagues15 reported functional connectivity of the amygdala with ventral medial prefrontal regions (including the medial frontal gyrus and rostral ACC), insula, thalamus and striatum at rest and anticorrelations with the dorsal ACC, superior frontal gyrus, bilateral middle frontal gyrus and posterior cingulate cortex (PCC)”
From Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder (2012) · cites this paper as [15]
Anticorrelations were found between the amygdala and medial prefrontal regions, including the dorsal and rostral ACC, consistent with the a priori hypothesis.
“Consistent with previous resting-state functional connectivity studies14,15 and effective connectivity studies,17,54 we found anticorrelations between the amygdala and medial prefrontal regions, including the dorsal and rostral ACC, consistent with our a priori hypothesis.”
From Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder (2012) · cites this paper as [15]
Recent resting-state functional connectivity studies of the amygdala have used global regression and identified networks proposed to be anticorrelated with the amygdala.
“In sum, recent resting-state functional connectivity studies of the amygdala have used global regression and identified networks proposed to be anticorrelated with the amygdala (for example, see Roy and colleagues15)”
From Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder (2012) · cites this paper as [15]
A recent connectivity modelling analysis found a strong functional link between the PCC and the amygdala in healthy individuals.
“A recent connectivity modelling analysis found a strong functional link between the PCC and the amygdala in healthy individuals.15”
From Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder (2012) · cites this paper as [15]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900 · see citing works
Functional connectivity in the motor cortex of resting human brain using echo‐planar mri
Biswal, B., Zerrin Yetkin, F., Haughton, V. M., & Hyde, J. S. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910340409 · Cited by 9,812 · see citing works
Self-citationThe human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553 · see citing works
Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527 · see citing works
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444 · see citing works
Mapping the structural core of human cerebral cortex
Hagmann, P., Cammoun, L., Gigandet, X., Meuli, R., Honey, C. J., Wedeen, V. J., & Sporns, O. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060159 · Cited by 4,173 · see citing works
Contributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377 · see citing works
Contributions of the Amygdala to Emotion Processing: From Animal Models to Human Behavior
Phelps, E. A., & LeDoux, J. E. (2005) · Neuron · doi:10.1016/j.neuron.2005.09.025 · Cited by 3,203 · see citing works
Temporal Autocorrelation in Univariate Linear Modeling of FMRI Data
Woolrich, M. W., Ripley, B. D., Brady, M., & Smith, S. M. (2001) · NeuroImage · doi:10.1006/nimg.2001.0931 · Cited by 2,859 · see citing works
Achard, S., Salvador, R., Whitcher, B., Suckling, J., & Bullmore, E. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3874-05.2006 · Cited by 2,393 · see citing works
Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network
Greicius, M. D., Supekar, K., Menon, V., & Dougherty, R. F. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn059 · Cited by 2,175 · see citing works
Neurobiology of emotion perception I: the neural basis of normal emotion perception
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00168-9 · Cited by 2,173 · see citing works
Ochsner, K. N., Ray, R. D., Cooper, J. C., Robertson, E. R., Chopra, S., Gabrieli, J. D. E., & Gross, J. J. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.06.030 · Cited by 2,113 · see citing works
Pezawas, L., Meyer-Lindenberg, A., Drabant, E. M., Verchinski, B. A., Munoz, K. E., Kolachana, B. S., Egan, M. F., Mattay, V. S., Hariri, A. R., & Weinberger, D. R. (2005) · Nature Neuroscience · doi:10.1038/nn1463 · Cited by 1,980 · see citing works
The Emotional Brain, Fear, and the Amygdala
LeDoux, J. (2003) · Cellular and Molecular Neurobiology · doi:10.1023/a:1025048802629 · Cited by 1,818 · see citing works
Intrinsic functional architecture in the anaesthetized monkey brain
Vincent, J. L., Patel, G. H., Fox, M. D., Snyder, A. Z., Baker, J. T., Van Essen, D. C., Zempel, J. M., Snyder, L. H., Corbetta, M., & Raichle, M. E. (2007) · Nature · doi:10.1038/nature05758 · Cited by 1,786 · see citing works
Disruption of Large-Scale Brain Systems in Advanced Aging
Andrews-Hanna, J. R., Snyder, A. Z., Vincent, J. L., Lustig, C., Head, D., Raichle, M. E., & Buckner, R. L. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.038 · Cited by 1,592 · see citing works
Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations
Lowe, M. J., Mock, B. J., & Sorenson, J. A. (1998) · NeuroImage · doi:10.1006/nimg.1997.0315 · Cited by 1,394 · see citing works
Fransson, P. (2005) · Human Brain Mapping · doi:10.1002/hbm.20113 · Cited by 1,388 · see citing works
Swanson, L. W., & Petrovich, G. D. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01265-x · Cited by 1,351 · see citing works
Competition between functional brain networks mediates behavioral variability
Kelly, A. M. C., Uddin, L. Q., Biswal, B. B., Castellanos, F. X., & Milham, M. P. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2007.08.008 · Cited by 1,287 · see citing works
Self-citationLeDoux, J. (2007) · Current Biology · doi:10.1016/j.cub.2007.08.005 · Cited by 1,281 · see citing works
Modulating emotional responses: effects of a neocortical network on the limbic system
Hariri, A. R., Bookheimer, S. Y., & Mazziotta, J. C. (2000) · NeuroReport · doi:10.1097/00001756-200001170-00009 · Cited by 1,277 · see citing works
Amunts, K., Kedo, O., Kindler, M., Pieperhoff, P., Mohlberg, H., Shah, N. J., Habel, U., Schneider, F., & Zilles, K. (2005) · Anatomy and Embryology · doi:10.1007/s00429-005-0025-5 · Cited by 1,264 · see citing works
Amygdalo‐cortical projections in the monkey ( <i>Macaca fascicularis</i> )
Amaral, D. G., & Price, J. L. (1984) · Journal of Comparative Neurology · doi:10.1002/cne.902300402 · Cited by 1,162 · see citing works
Uddin, L. Q., Clare Kelly, A. M., Biswal, B. B., Xavier Castellanos, F., & Milham, M. P. (2009) · Human Brain Mapping · doi:10.1002/hbm.20531 · Cited by 1,135 · see citing works
Self-citationFunctional connectivity of human striatum: a resting state FMRI study
Di Martino, A., Scheres, A., Margulies, D. S., Kelly, A. M. C., Uddin, L. Q., Shehzad, Z., Biswal, B., Walters, J. R., Castellanos, F. X., & Milham, M. P. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn041 · Cited by 1,090 · see citing works
Self-citationThe human amygdala and the emotional evaluation of sensory stimuli
Zald, D. H. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00248-5 · Cited by 1,062 · see citing works
The Amygdala: a functional analysis
Aggleton, J. P. (2000) · Cited by 964 · see citing works
Castellanos, F. X., Margulies, D. S., Kelly, C., Uddin, L. Q., Ghaffari, M., Kirsch, A., Shaw, D., Shehzad, Z., Di Martino, A., Biswal, B., et al. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.025 · Cited by 854 · see citing works
Self-citationNeocortical modulation of the amygdala response to fearful stimuli
Hariri, A. R., Mattay, V. S., Tessitore, A., Fera, F., & Weinberger, D. R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01786-9 · Cited by 828 · see citing works
Zald, D. H., & Pardo, J. V. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.8.4119 · Cited by 826 · see citing works
Human Amygdala Responsivity to Masked Fearful Eye Whites
Whalen, P. J., Kagan, J., Cook, R. G., Davis, F. C., Kim, H., Polis, S., McLaren, D. G., Somerville, L. H., McLean, A. A., Maxwell, J. S., et al. (2004) · Science · doi:10.1126/science.1103617 · Cited by 766 · see citing works
Intrinsic Fluctuations within Cortical Systems Account for Intertrial Variability in Human Behavior
Fox, M., Snyder, A. Z., Vincent, J. L., & Raichle, M. E. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.023 · Cited by 753 · see citing works
Mapping the functional connectivity of anterior cingulate cortex
Margulies, D. S., Kelly, C. A. M., Uddin, L. Q., Biswal, B. B., Castellanos, F. X., & Milham, M. P. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.05.019 · Cited by 751 · see citing works
Self-citationAmygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter
Heinz, A., Braus, D. F., Smolka, M. N., Wrase, J., Puls, I., Hermann, D., Vollstädt‐Klein, S., Grüsser, S. M., Flor, H., Schumann, G., et al. (2004) · Nature Neuroscience · doi:10.1038/nn1366 · Cited by 700 · see citing works
How default is the default mode of brain function?
Fransson, P. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.06.017 · Cited by 611 · see citing works
Neural systems involved in fear and anxiety measured with fear-potentiated startle.
Davis, M. (2006) · American Psychologist · doi:10.1037/0003-066x.61.8.741 · Cited by 589 · see citing works
Postuma, R. B., & Dagher, A. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhj088 · Cited by 579 · see citing works
Development of Anterior Cingulate Functional Connectivity from Late Childhood to Early Adulthood
Kelly, A. M. C., Di Martino, A., Uddin, L. Q., Shehzad, Z., Gee, D. G., Reiss, P. T., Margulies, D. S., Castellanos, F. X., & Milham, M. P. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn117 · Cited by 572 · see citing works
Self-citationNeurobiology of fear responses: the role of the amygdala
Davis, M. (1997) · Journal of Neuropsychiatry · doi:10.1176/jnp.9.3.382 · Cited by 562 · see citing works
Effects of D-Cycloserine on Extinction: Translation From Preclinical to Clinical Work
Davis, M., Ressler, K., Rothbaum, B. O., & Richardson, R. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.084 · Cited by 498 · see citing works
A review of systems and networks of the limbic forebrain/limbic midbrain
Morgane, P. J., Galler, J. R., & Mokler, D. J. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.01.001 · Cited by 497 · see citing works
Amygdala core nuclei volumes are decreased in recurrent major depression
Sheline, Y. I., Gado, M. H., & Price, J. L. (1998) · NeuroReport · doi:10.1097/00001756-199806220-00021 · Cited by 472 · see citing works
Network homogeneity reveals decreased integrity of default-mode network in ADHD
Uddin, L. Q., Kelly, A. M. C., Biswal, B. B., Margulies, D. S., Shehzad, Z., Shaw, D., Ghaffari, M., Rotrosen, J., Adler, L. A., Castellanos, F. X., et al. (2008) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2007.11.031 · Cited by 452 · see citing works
Self-citationComparative aspects of amygdala connectivity
PRICE, J. L. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07070.x · Cited by 442 · see citing works
Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder
McClure, E. B., Monk, C. S., Nelson, E. E., Parrish, J. M., Adler, A., Blair, R. J. R., Fromm, S., Charney, D. S., Leibenluft, E., Ernst, M., et al. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.1.97 · Cited by 431 · see citing works
Modulation of emotion by cognition and cognition by emotion
Blair, K. S., Smith, B. W., Mitchell, D. G. V., Morton, J., Vythilingam, M., Pessoa, L., Fridberg, D. J., Zametkin, A. J., Nelson, E. E., Drevets, W. C., et al. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.11.048 · Cited by 402 · see citing works
The amygdalostriatal projections in the monkey. An anterograde tracing study
Russchen, F. T., Bakst, I., Amaral, D. G., & Price, J. L. (1985) · Brain Research · doi:10.1016/0006-8993(85)90530-x · Cited by 395 · cited 2× · see citing works
“Considering the amygdala as a single unit, as is common in most human neuroimaging studies, potentially overlooks the independent functions and patterns of connectivity of individual subdivisions (laterobasal, centromedial, and superficial), and their component nuclei, that have been discerned in animals (Pitkanen, 20…”
BackgroundA validated network of effective amygdala connectivity
Stein, J. L., Wiedholz, L. M., Bassett, D. S., Weinberger, D. R., Zink, C. F., Mattay, V. S., & Meyer-Lindenberg, A. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.03.022 · Cited by 392 · see citing works
Functional Coactivation Map of the Human Brain
Toro, R., Fox, P. T., & Paus, T. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn014 · Cited by 378 · see citing works
The limbic lobe and its output channels: implications for emotional functions and adaptive behavior
Heimer, L., & Van Hoesen, G. W. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.06.006 · Cited by 366 · see citing works
Inverse amygdala and medial prefrontal cortex responses to surprised faces
Kim, H., Somerville, L. H., Johnstone, T., Alexander, A. L., & Whalen, P. J. (2003) · NeuroReport · doi:10.1097/00001756-200312190-00006 · Cited by 359 · see citing works
McNally, R. J. (2007) · Clinical Psychology Review · doi:10.1016/j.cpr.2007.01.003 · Cited by 348 · see citing works
Inhibition of the Amygdala: Key to Pathological States?
Quirk, G. J., & Gehlert, D. R. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07087.x · Cited by 308 · see citing works
Akirav, I., & Maroun, M. (2007) · Neural Plasticity · doi:10.1155/2007/30873 · Cited by 277 · see citing works
Koski, L. M., & Paus, T. (2000) · Experimental Brain Research · doi:10.1007/s002210000400 · Cited by 267 · see citing works
Task instructions modulate neural responses to fearful facial expressions
Lange, K., Williams, L. M., Young, A. W., Bullmore, E. T., Brammer, M. J., Williams, S. C. R., Gray, J. A., & Phillips, M. L. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01455-5 · Cited by 226 · see citing works
Schoenbaum, G. M., Chiba, A. A., & Gallagher, M. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-13-05179.2000 · Cited by 223 · see citing works
Morris, J. S., Büchel, C., & Dolan, R. J. (2001) · NeuroImage · doi:10.1006/nimg.2000.0721 · Cited by 212 · see citing works
Ball, T., Rahm, B., Eickhoff, S. B., Schulze-Bonhage, A., Speck, O., & Mutschler, I. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000307 · Cited by 176 · see citing works
Functional MRI of the Human Amygdala?
Merboldt, K., Fransson, P., Bruhn, H., & Frahm, J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0802 · Cited by 162 · see citing works
The Amygdala and Its Place in the Cerebral Hemisphere
Swanson, L. W. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07081.x · Cited by 161 · see citing works
Amygdalohippocampal and Amygdalocortical Projections in the Primate Brain
Amaral, D. G. (1986) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-7971-3_1 · Cited by 158 · see citing works
Kapp, B. S., Supple, W. F., & Whalen, P. J. (1994) · Behavioral Neuroscience · doi:10.1037//0735-7044.108.1.81 · Cited by 152 · see citing works
Enhancing exposure-based therapy from a translational research perspective
Hofmann, S. G. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2007.06.006 · Cited by 133 · see citing works
Kapp, B. S., Supple, W. F., & Whalen, P. J. (1994) · Behavioral Neuroscience · doi:10.1037/0735-7044.108.1.81 · Cited by 120 · see citing works
Kemppainen, S., Jolkkonen, E., & Pitkänen, A. (2002) · Hippocampus · doi:10.1002/hipo.10020 · Cited by 91 · see citing works
Enhanced amygdala responses to emotional versus neutral schematic facial expressions
Wright, C. I., Martis, B., Shin, L. M., Fischer, H., & Rauch, S. L. (2002) · Neuroreport · doi:10.1097/00001756-200205070-00010 · Cited by 90 · see citing works
Irwin, W., Anderle, M. J., Abercrombie, H. C., Schaefer, S. M., Kalin, N. H., & Davidson, R. J. (2003) · NeuroImage · doi:10.1016/j.neuroimage.2003.09.057 · Cited by 87 · see citing works
Zald, D. H., Donndelinger, M. J., & Pardo, J. V. (1998) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-199808000-00010 · Cited by 80 · see citing works
Gonzalez-Lima, F., & Scheich, H. (1986) · Brain Research · doi:10.1016/0006-8993(86)91009-7 · Cited by 76 · see citing works
Reciprocal Changes in the Firing Probability of Lateral and Central Medial Amygdala Neurons
Collins, D. R., & Paré, D. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-02-00836.1999 · Cited by 70 · see citing works
Integrated volume visualization of functional image data and anatomical surfaces using normal fusion
Stokking, R., Zuiderveld, K. J., & Viergever, M. A. (2001) · Human Brain Mapping · doi:10.1002/1097-0193(200104)12:4 · Cited by 24 · see citing works
Berretta, S. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07112.x · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The organization of the human cerebellum estimated by intrinsic functional connectivity
Buckner, R. L., Krienen, F. M., Castellanos, A., Diaz, J. C., & Yeo, B. T. T. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00339.2011 · Cited by 7,304 · see citing works
<i>Conn</i> : A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
Whitfield-Gabrieli, S., & Nieto-Castanon, A. (2012) · Brain Connectivity · doi:10.1089/brain.2012.0073 · Cited by 4,885 · see citing works
Toward discovery science of human brain function
Biswal, B. B., Mennes, M., Zuo, X.-N., Gohel, S., Kelly, C., Smith, S. M., Beckmann, C. F., Adelstein, J. S., Buckner, R. L., Colcombe, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911855107 · Cited by 2,970 · see citing works
Self-citationThe integration of negative affect, pain and cognitive control in the cingulate cortex
Shackman, A. J., Salomons, T. V., Slagter, H. A., Fox, A. S., Winter, J. J., & Davidson, R. J. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn2994 · Cited by 2,082 · see citing works
Van Dijk, K. R. A., Hedden, T., Venkataraman, A., Evans, K. C., Lazar, S. W., & Buckner, R. L. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00783.2009 · Cited by 1,844 · see citing works
Default Mode Network Activity and Connectivity in Psychopathology
Whitfield-Gabrieli, S., & Ford, J. M. (2012) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032511-143049 · Cited by 1,465 · see citing works
Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress
Milad, M. R., & Quirk, G. J. (2012) · Annual Review of Psychology · doi:10.1146/annurev.psych.121208.131631 · Cited by 1,466 · see citing works
Behavioral interpretations of intrinsic connectivity networks
Laird, A. R., Fox, P. M., Eickhoff, S. B., Turner, J. A., Ray, K. L., McKay, D. R., Glahn, D. C., Beckmann, C. F., Smith, S. M., & Fox, P. T. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00077 · Cited by 1,023 · see citing works
Neurobiology of Aggression and Violence
Siever, L. J. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07111774 · Cited by 984 · see citing works
Kim, M. J., Loucks, R. A., Palmer, A. L., Brown, A. C., Solomon, K. M., Marchante, A. N., & Whalen, P. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.04.025 · Cited by 838 · see citing works
Childhood Adversity and Neural Development: A Systematic Review
McLaughlin, K. A., Weissman, D., & Bitrán, D. (2019) · Annual Review of Developmental Psychology · doi:10.1146/annurev-devpsych-121318-084950 · Cited by 892 · see citing works
The organization of the human striatum estimated by intrinsic functional connectivity
Choi, E. Y., Yeo, B. T. T., & Buckner, R. L. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00270.2012 · Cited by 746 · see citing works
Zuo, X.-N., Kelly, C., Adelstein, J. S., Klein, D. F., Castellanos, F. X., & Milham, M. P. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.10.080 · Cited by 744 · see citing works
Self-citationA Developmental Shift from Positive to Negative Connectivity in Human Amygdala–Prefrontal Circuitry
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3446-12.2013 · Cited by 731 · see citing works
Social functioning in major depressive disorder
Kupferberg, A., Bicks, L., & Hasler, G. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.002 · Cited by 663 · see citing works
Freeze for action: neurobiological mechanisms in animal and human freezing
Roelofs, K. (2017) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2016.0206 · Cited by 616 · see citing works
Modalities, Modes, and Models in Functional Neuroimaging
Friston, K. J. (2009) · Science · doi:10.1126/science.1174521 · Cited by 489 · see citing works
Hahn, A., Stein, P., Windischberger, C., Weissenbacher, A., Spindelegger, C., Moser, E., Kasper, S., & Lanzenberger, R. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.02.064 · Cited by 385 · see citing works
Kim, M. J., Gee, D. G., Loucks, R. A., Davis, F. C., & Whalen, P. J. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq237 · Cited by 388 · see citing works
A convergent functional architecture of the insula emerges across imaging modalities
Kelly, C., Toro, R., Di Martino, A., Cox, C. L., Bellec, P., Castellanos, F. X., & Milham, M. P. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.03.021 · Cited by 374 · see citing works
Self-citationGabard-Durnam, L. J., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.03.038 · Cited by 372 · see citing works
Di Martino, A., Zuo, X.-N., Kelly, C., Grzadzinski, R., Mennes, M., Schvarcz, A., Rodman, J., Lord, C., Castellanos, F. X., & Milham, M. P. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.02.011 · Cited by 345 · see citing works
Self-citationAltered resting-state amygdala functional connectivity in men with posttraumatic stress disorder
Sripada, R. K., King, A. P., Garfinkel, S. N., Wang, X., Sripada, C. S., Welsh, R. C., & Liberzon, I. (2012) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.110069 · Cited by 352 · see citing works
Hanson, J. L., Hariri, A. R., & Williamson, D. E. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.05.010 · Cited by 338 · see citing works
Abnormal Amygdala Resting-State Functional Connectivity in Adolescent Depression
Cullen, K. R., Westlund, M. K., Klimes-Dougan, B., Mueller, B. A., Houri, A., Eberly, L. E., & Lim, K. O. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.1087 · Cited by 324 · see citing works
Metaanalytic connectivity modeling: Delineating the functional connectivity of the human amygdala
Robinson, J. L., Laird, A. R., Glahn, D. C., Lovallo, W. R., & Fox, P. T. (2010) · Human Brain Mapping · doi:10.1002/hbm.20854 · Cited by 327 · see citing works
Prenatal maternal depression alters amygdala functional connectivity in 6-month-old infants
Qiu, A., Anh, T. T., Li, Y., Chen, H., Rifkin-Graboi, A., Broekman, B. F. P., Kwek, K., Saw, S.-M., Chong, Y.-S., Gluckman, P. D., et al. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.3 · Cited by 282 · see citing works
Intrinsic Amygdala–Cortical Functional Connectivity Predicts Social Network Size in Humans
Bickart, K. C., Hollenbeck, M. C., Barrett, L. F., & Dickerson, B. C. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.1599-12.2012 · Cited by 272 · see citing works
Nicholson, A. A., Rabellino, D., Densmore, M., Frewen, P. A., Paret, C., Kluetsch, R., Schmahl, C., Théberge, J., Neufeld, R. W. J., McKinnon, M. C., et al. (2017) · Human Brain Mapping · doi:10.1002/hbm.23402 · Cited by 273 · see citing works
Baur, V., Hänggi, J., Langer, N., & Jäncke, L. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.003 · Cited by 258 · see citing works
Oxytocin facilitates protective responses to aversive social stimuli in males
Striepens, N., Scheele, D., Kendrick, K. M., Becker, B., Schäfer, L., Schwalba, K., Reul, J., Maier, W., & Hurlemann, R. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208852109 · Cited by 242 · see citing works
Qin, S., Young, C. B., Duan, X., Chen, T., Supekar, K., & Menon, V. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.10.006 · Cited by 249 · see citing works
Altered amygdala resting-state functional connectivity in post-traumatic stress disorder
Rabinak, C. A., Angstadt, M., Welsh, R. C., Kenndy, A. E., Lyubkin, M., Martis, B., & Phan, K. L. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00062 · Cited by 230 · see citing works
Di Martino, A., Shehzad, Z., Kelly, C., Roy, A. K., Gee, D. G., Uddin, L. Q., Gotimer, K., Klein, D. F., Castellanos, F. X., & Milham, M. P. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08121894 · Cited by 213 · see citing works
Self-citationAbnormal amygdala connectivity in patients with primary insomnia: Evidence from resting state fMRI
Huang, Z., Liang, P., Jia, X., Zhan, S., Li, N., Ding, Y., Lu, J., Wang, Y., & Li, K. (2012) · European Journal of Radiology · doi:10.1016/j.ejrad.2011.03.029 · Cited by 194 · see citing works
Nicholson, A. A., Densmore, M., Frewen, P. A., Théberge, J., Neufeld, R. W., McKinnon, M. C., & Lanius, R. A. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.79 · Cited by 180 · see citing works
Alterations in amygdala–prefrontal circuits in infants exposed to prenatal maternal depression
Posner, J., Cha, J., Roy, A. K., Peterson, B. S., Bansal, R., Gustafsson, H. C., Raffanello, E., Gingrich, J., & Monk, C. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.146 · Cited by 184 · see citing works
Self-citationWhite, M. G., Bogdan, R., Fisher, P. M., Muñoz, K. E., Williamson, D. E., & Hariri, A. R. (2012) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2012.00837.x · Cited by 180 · see citing works
Avery, S. N., Clauss, J. A., Winder, D. G., Woodward, N., Heckers, S., & Blackford, J. U. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.01.017 · Cited by 164 · see citing works
Pathogenesis and pathophysiology of functional (psychogenic) movement disorders
Baizabal-Carvallo, J. F., Hallett, M., & Jankovic, J. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.02.013 · Cited by 163 · see citing works
Pannekoek, J. N., van der Werff, S. J. A., Meens, P. H. F., van den Bulk, B. G., Jolles, D. D., Veer, I. M., van Lang, N. D. J., Rombouts, S. A. R. B., van der Wee, N. J. A., & Vermeiren, R. R. J. M. (2014) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12266 · Cited by 150 · see citing works
Long-term consequences of childhood maltreatment: altered amygdala functional connectivity
Jedd, K., Hunt, R. H., Cicchetti, D., Hunt, E., Cowell, R. A., Rogosch, F. A., Toth, S. L., & Thomas, K. M. (2015) · Development and Psychopathology · doi:10.1017/s0954579415000954 · Cited by 149 · see citing works
Fear bradycardia and activation of the human periaqueductal grey
Hermans, E. J., Henckens, M. J. A. G., Roelofs, K., & Fernández, G. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2012.10.063 · Cited by 151 · see citing works
Veer, I. M., Oei, N. Y. L., Spinhoven, P., van Buchem, M. A., Elzinga, B. M., & Rombouts, S. A. R. B. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.12.001 · Cited by 140 · see citing works
Intranasal Oxytocin Normalizes Amygdala Functional Connectivity in Posttraumatic Stress Disorder
Koch, S. B. J., van Zuiden, M., Nawijn, L., Frijling, J. L., Veltman, D. J., & Olff, M. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.1 · Cited by 132 · see citing works
Hulvershorn, L. A., Mennes, M., Castellanos, F. X., Di Martino, A., Milham, M. P., Hummer, T. A., & Roy, A. K. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2013.11.012 · Cited by 138 · see citing works
Self-citationImplications of newborn amygdala connectivity for fear and cognitive development at 6-months-of-age
Graham, A. M., Buss, C., Rasmussen, J. M., Rudolph, M. D., Demeter, D. V., Gilmore, J. H., Styner, M., Entringer, S., Wadhwa, P. D., & Fair, D. A. (2016) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2015.09.006 · Cited by 122 · see citing works
Westlund Schreiner, M., Klimes-Dougan, B., Mueller, B. A., Eberly, L. E., Reigstad, K. M., Carstedt, P. A., Thomas, K. M., Hunt, R. H., Lim, K. O., & Cullen, K. R. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.06.004 · Cited by 126 · see citing works
Altered amygdala connectivity in urban youth exposed to trauma
Thomason, M. E., Marusak, H. A., Tocco, M. A., Vila, A. M., McGarragle, O., & Rosenberg, D. R. (2015) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsv030 · Cited by 127 · see citing works
“Despite these considerations, cytoarchitechtonically based amygdala FC analyses have yielded consistent, replicated delineation of differential connectivity of major amygdala subregions (Etkin et al., 2009; Roy et al., 2009; Roy et al., 2013; Brown et al., 2014 ).”
BackgroundMethodResultInfluentialImmature integration and segregation of emotion-related brain circuitry in young children
Qin, S., Young, C. B., Supekar, K., Uddin, L. Q., & Menon, V. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120408109 · Cited by 130 · see citing works
Self-citationThe Physiology of Fear: Reconceptualizing the Role of the Central Amygdala in Fear Learning
Keifer, O. P., Hurt, R. C., Ressler, K. J., & Marvar, P. J. (2015) · Physiology · doi:10.1152/physiol.00058.2014 · Cited by 124 · see citing works
Jiang, Y., Oathes, D., Hush, J., Darnall, B., Charvat, M., Mackey, S., & Etkin, A. (2016) · Pain · doi:10.1097/j.pain.0000000000000606 · Cited by 120 · see citing works
Overview of human oxytocin research
Kendrick, K. M., Guastella, A. J., & Becker, B. (2017) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2017_19 · Cited by 121 · see citing works
Kang, S.-G., Na, K.-S., Choi, J.-W., Kim, J.-H., Son, Y.-D., & Lee, Y. J. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.04.029 · Cited by 110 · see citing works
Hyper-connectivity of subcortical resting state networks in social anxiety disorder
Arnold Anteraper, S., Triantafyllou, C., Sawyer, A. T., Hofmann, S. G., Gabrieli, J. D., & Whitfield-Gabrieli, S. (2014) · Brain Connectivity · doi:10.1089/brain.2013.0180 · Cited by 101 · see citing works
Subjective uncertainty and limbic hyperactivation in obsessive‐compulsive disorder
Stern, E. R., Welsh, R. C., Gonzalez, R., Fitzgerald, K. D., Abelson, J. L., & Taylor, S. F. (2013) · Human Brain Mapping · doi:10.1002/hbm.22038 · Cited by 102 · see citing works
Developmental sex differences in resting state functional connectivity of amygdala sub-regions
Alarcón, G., Cservenka, A., Rudolph, M. D., Fair, D. A., & Nagel, B. J. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.04.013 · Cited by 105 · see citing works
Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening
Marcus, D. J., Bedse, G., Gaulden, A. D., Ryan, J. D., Kondev, V., Winters, N. D., Rosas-Vidal, L. E., Altemus, M., Mackie, K., Lee, F. S., et al. (2020) · Neuron · doi:10.1016/j.neuron.2019.12.024 · Cited by 104 · see citing works
Amygdala subnuclei resting-state functional connectivity sex and estrogen differences
Engman, J., Linnman, C., Van Dijk, K. R. A., & Milad, M. R. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.09.012 · Cited by 89 · see citing works
Using executive control training to suppress amygdala reactivity to aversive information
Cohen, N., Margulies, D. S., Ashkenazi, S., Schaefer, A., Taubert, M., Henik, A., Villringer, A., & Okon-Singer, H. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2015.10.069 · Cited by 90 · see citing works
Self-citationCastellanos, F. X., Kelly, C., & Milham, M. P. (2009) · The Canadian Journal of Psychiatry · doi:10.1177/070674370905401003 · Cited by 88 · see citing works
Self-citationMarusak, H. A., Thomason, M. E., Peters, C., Zundel, C., Elrahal, F., & Rabinak, C. A. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.218 · Cited by 88 · see citing works
Sex differences in the functional connectivity of the amygdalae in association with cortisol
Kogler, L., Müller, V. I., Seidel, E.-M., Boubela, R., Kalcher, K., Moser, E., Habel, U., Gur, R. C., Eickhoff, S. B., & Derntl, B. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.03.064 · Cited by 78 · see citing works
Dose-Dependent Effects of Intranasal Insulin on Resting-State Brain Activity
Kullmann, S., Veit, R., Peter, A., Pohmann, R., Scheffler, K., Häring, H.-U., Fritsche, A., Preissl, H., & Heni, M. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-01976 · Cited by 78 · see citing works
Göttlich, M., Krämer, U. M., Kordon, A., Hohagen, F., & Zurowski, B. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2015.09.004 · Cited by 73 · see citing works
Amygdala subregions tied to SSRI and placebo response in patients with social anxiety disorder
Faria, V., Appel, L., Åhs, F., Linnman, C., Pissiota, A., Frans, Ö., Bani, M., Bettica, P., Pich, E. M., Jacobsson, E., et al. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.72 · Cited by 73 · see citing works
Oler, J. A., Birn, R. M., Patriat, R., Fox, A. S., Shelton, S. E., Burghy, C. A., Stodola, D. E., Essex, M. J., Davidson, R. J., & Kalin, N. H. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.03.045 · Cited by 67 · see citing works
Amygdala–cingulate intrinsic connectivity is associated with degree of social inhibition
Blackford, J. U., Clauss, J. A., Avery, S. N., Cowan, R. L., Benningfield, M. M., & VanDerKlok, R. M. (2014) · Biological Psychology · doi:10.1016/j.biopsycho.2014.02.003 · Cited by 67 · see citing works
Testosterone during puberty shifts emotional control from pulvinar to anterior prefrontal cortex
Tyborowska, A., Volman, I., Smeekens, S., Toni, I., & Roelofs, K. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.3874-15.2016 · Cited by 67 · see citing works
Sripada, R. K., Welsh, R. C., Marx, C. E., & Liberzon, I. (2014) · Human Brain Mapping · doi:10.1002/hbm.22399 · Cited by 66 · see citing works
Behavioural and neural correlates of self-focused emotion regulation in social anxiety disorder
Gaebler, M., Daniels, J. K., Lamke, J.-P., Fydrich, T., & Walter, H. (2014) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.130080 · Cited by 64 · see citing works
Fullana, M. A., Zhu, X., Alonso, P., Cardoner, N., Real, E., López-Solà, C., Segalàs, C., Subirà, M., Galfalvy, H., Menchón, J. M., et al. (2017) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.160215 · Cited by 63 · see citing works
Krause-Utz, A., Winter, D., Schriner, F., Chiu, C.-D., Lis, S., Spinhoven, P., Bohus, M., Schmahl, C., & Elzinga, B. M. (2018) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-017-0806-x · Cited by 57 · see citing works
Limbic Intrinsic Connectivity in Depressed and High-Risk Youth
Singh, M. K., Leslie, S. M., Packer, M. M., Weisman, E. F., & Gotlib, I. H. (2018) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2018.06.017 · Cited by 54 · see citing works
Prenatal and postnatal maternal anxiety and amygdala structure and function in young children
Donnici, C., Long, X., Dewey, D., Letourneau, N., Landman, B., Huo, Y., & Lebel, C. (2021) · Scientific Reports · doi:10.1038/s41598-021-83249-2 · Cited by 54 · see citing works
Neuropathology of the Anterior Midcingulate Cortex in Young Children With Autism
Uppal, N., Wicinski, B., Buxbaum, J. D., Heinsen, H., Schmitz, C., & Hof, P. R. (2014) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0000000000000108 · Cited by 52 · see citing works
Deep brain stimulation modulates directional limbic connectivity in obsessive-compulsive disorder
Fridgeirsson, E. A., Figee, M., Luigjes, J., van den Munckhof, P., Schuurman, P. R., van Wingen, G., & Denys, D. (2020) · Brain · doi:10.1093/brain/awaa100 · Cited by 51 · see citing works
Adolescent risk-taking and resting state functional connectivity
DeWitt, S. J., Aslan, S., & Filbey, F. M. (2014) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2014.03.009 · Cited by 45 · see citing works
Sex differences in amygdala subregions: evidence from subregional shape analysis
Kim, H. J., Kim, N., Kim, S., Hong, S., Park, K., Lim, S., Park, J.-M., Na, B., Chae, Y., Lee, J., et al. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.02.025 · Cited by 40 · see citing works
Amygdala-frontal couplings characterizing SSRI and placebo response in social anxiety disorder
Faria, V., Åhs, F., Appel, L., Linnman, C., Bani, M., Bettica, P., Pich, E. M., Fredrikson, M., & Furmark, T. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145714000352 · Cited by 37 · see citing works
Morin, E. L., Howell, B. R., Feczko, E., Earl, E., Pincus, M., Reding, K., Kovacs-Balint, Z. A., Meyer, J. S., Styner, M., Fair, D., et al. (2020) · Development and Psychopathology · doi:10.1017/s0954579420001133 · Cited by 37 · see citing works
Li, Z., Santhanam, P., Coles, C. D., Ellen Lynch, M., Hamann, S., Peltier, S., & Hu, X. (2013) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2012.12.005 · Cited by 36 · see citing works
Cullen, K. R., Schreiner, M. W., Klimes-Dougan, B., Eberly, L. E., LaRiviere, L. L., Lim, K. O., Camchong, J., & Mueller, B. A. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109778 · Cited by 34 · see citing works
Aberrant spontaneous and task-dependent functional connections in the anxious brain
MacNamara, A., DiGangi, J., & Phan, K. L. (2016) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2015.12.004 · Cited by 34 · see citing works
Psychogenic nonepileptic seizures: Are they a freeze reaction?
Schneider, G., Levin, L., & Herskovitz, M. (2022) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2022.108655 · Cited by 12 · see citing works
Kim, N., Kim, H. J., Hwang, J., Yoon, S. J., Cho, H. B., Renshaw, P. F., Lyoo, I. K., & Kim, J. E. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2010.11.005 · Cited by 11 · see citing works
- Authors
- Roy, A. K., Shehzad, Z., Margulies, D. S., Kelly, A. M. C., Uddin, L. Q., Gotimer, K., Biswal, B. B., Castellanos, F. X., & Milham, M. P.
- Affiliations
- New York University (US)
- NYU Langone Health (US)
- Humboldt-Universität zu Berlin (DE)
- Rutgers, The State University of New Jersey (US)
- Nathan Kline Institute for Psychiatric Research (US)
- Corresponding author
- Roy, Amy Krain
- ORCID
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2009-04
- Volume
- 45
- Issue
- 2
- Pages
- 614-626
- ISSN
- 1053-8119 (ISSN-L)
- PMC
- PMC2735022
- OpenAlex
- W2106089606
- Cited by
- 749
- References
- 75
- Citations by year
- 2026: 15 · 2025: 27 · 2024: 27 · 2023: 36 · 2022: 49 · 2021: 46 · 2020: 48 · 2019: 43 · 2018: 53 · 2017: 56 · 2016: 74 · 2015: 53 · 2014: 52 · 2013: 53 · 2012: 43
- FWCI
- 12.58
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- Fordham Research Commons (Fordham University) (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Funders
- National Institute of Mental Health (K23MH074821)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- amygdala, functional connectivity, resting state, centromedial amygdala, superficial amygdala, emotional processing, limbic system, striatum, temporal lobe, frontal lobe
- MeSH terms
- Adult, Amygdala, Brain Mapping, Female, Humans, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Male, Nerve Net, Neural Pathways, Rest
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
