Cited by 465Characterization and Applications of Magnetic NanoparticlesLanthanide and Transition Metal ComplexesNanoparticle-Based Drug Delivery

Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes

Ai, H., Flask, C., Weinberg, B., Shuai, X.‐T., Pagel, M. D., Farrell, D., Duerk, J., Gao, J.·2005·Advanced Materials

Abstract

Increased contrast in magnetic resonance imaging (MRI) is accomplished using polymeric micelles loaded with superparamagnetic iron oxide (SPIO) nanoparticles encapsulated in biocompatible, biodegradable poly(ϵ-caprolactone)-b-poly(ethylene glycol) (PCL-b-PEG) copolymers (see Figure). The loaded micelles show significantly improved T2 relaxivities and remarkable MRI detection sensitivity.

Integrity signals

Registry

Crossref · 10.1002/adma.200401904

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17 of 17 references verified0 citation errors · 0 not checkable

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Authors
Ai, H., Flask, C., Weinberg, B., Shuai, X. ‐., Pagel, M. D., Farrell, D., Duerk, J., & Gao, J.
Affiliations
Case Western Reserve University (US)
Venue
Advanced Materials
Publisher
Wiley
Published
2005-08-04
Volume
17
Issue
16
Pages
1949-1952
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W2076338426
Cited by
465
References
17
Citations by year
2025: 4 · 2024: 6 · 2023: 8 · 2022: 8 · 2021: 14 · 2020: 20 · 2019: 31 · 2018: 20 · 2017: 24 · 2016: 34 · 2015: 37 · 2014: 35 · 2013: 34 · 2012: 44
FWCI
8.87
Type
journal article
Language
en
Open access
closed
Locations
Advanced Materials (publishedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
  • Physical Sciences › Materials Science › Materials Chemistry › Lanthanide and Transition Metal Complexes
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Keywords
polymeric micelles, superparamagnetic iron oxide nanoparticles, magnetite, MRI contrast agents, T2 relaxivity, biodegradable polymers

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