Cited by 508Zoonotic diseases and public healthViral Infections and Outbreaks ResearchWildlife Ecology and Conservation

Global Patterns of Zoonotic Disease in Mammals

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Han, Barbara A., Kramer, Andrew M., Drake, John M.·2016·Trends in Parasitology

Abstract

As the frequency and prevalence of zoonotic diseases increase worldwide, investigating how mammal host distributions determine patterns of human disease and predicting which regions are at greatest risk for future zoonotic disease emergence are two goals which both require better understanding the current distributions of zoonotic hosts and pathogens. Here we review the existing data about mammalian host species, comparing and contrasting these patterns against global maps of zoonotic hosts from all 27 orders of terrestrial mammals. We discuss the zoonotic potential of host species from the top six most species-rich mammal groups, and review the literature to identify analytical and conceptual gaps that must be addressed to improve our ability to generate testable predictions about zoonotic diseases originating from wild mammals.

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Crossref · 10.1016/j.pt.2016.04.007

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  • Recent analyses identify rodents as the most likely source or one of the most likely sources of zoonotic pathogens.

    “In recent analyses, rodents have also emerged as the most likely source (21, 23) or one of the most likely (11, 27).”

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  1. [55]Cleaveland S. Diseases of humans and their domestic mammals: pathogen characteristics, host range and the risk of emergence Philos. Trans. R. Soc. Lond. B. Biol. Sci. 356 2001 991 999 11516377 PMC1088494

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Authors
Han, B. A., Kramer, A. M., & Drake, J. M.
Affiliations
  • Cary Institute of Ecosystem Studies (US)
  • University of Georgia (US)
Corresponding author
Han, Barbara A.
Venue
Trends in Parasitology
Publisher
Elsevier BV
Published
2016-07
Volume
32
Issue
7
Pages
565-577
ISSN
1471-4922 (ISSN-L)
OpenAlex
W2444422412
Cited by
508
References
94
Citations by year
2026: 37 · 2025: 58 · 2024: 53 · 2023: 67 · 2022: 59 · 2021: 101 · 2020: 58 · 2019: 26 · 2018: 23 · 2017: 23 · 2016: 2 · 2015: 1
FWCI
3.65
Type
journal article
Language
en
Open access
Locations
  • Trends in Parasitology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
Funders
National Institute of General Medical Sciences (U01GM110744, F32GM087811)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Zoonotic diseases and public health
  • Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
  • Physical Sciences › Environmental Science › Ecology › Wildlife Ecology and Conservation
Keywords
zoonoses, host distribution, terrestrial mammals, species richness, disease emergence, zoonotic potential, wild mammals, pathogen distribution, disease risk prediction
MeSH terms
Animals, Animals, Wild, Humans, Mammals, Risk Factors, Global Health, Zoonoses, Host-Pathogen Interactions

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