Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding

Central nervous system control of food intake

Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451 · see citing works

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R. M., Tanaka, H., Williams, S. C., Richardson, J. A., Kozlowski, G. P., Wilson, S., et al. (1998) · Cell · doi:10.1016/s0092-8674(00)80949-6 · Cited by 5,501 · see citing works

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Maffei, M., Halaas, J., Ravussin, E., Pratley, R. E., Lee, G. H., Zhang, Y., Fei, H., Kim, S., Lallone, R., Ranganathan, S., et al. (1995) · Nature Medicine · doi:10.1038/nm1195-1155 · Cited by 3,725 · see citing works

Narcolepsy in orexin Knockout Mice

Chemelli, R. M., Willie, J. T., Sinton, C. M., Elmquist, J. K., Scammell, T., Lee, C., Richardson, J. A., Williams, S. C., Xiong, Y., Kisanuki, Y., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)81973-x · Cited by 3,095 · see citing works

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

Tatemoto, K., Hosoya, M., Habata, Y., Fujii, R., Kakegawa, T., Zou, M.-X., Kawamata, Y., Fukusumi, S., Hinuma, S., Kitada, C., et al. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9489 · Cited by 1,684 · see citing works

The sleep switch: hypothalamic control of sleep and wakefulness

Saper, C. B., Chou, T. C., & Scammell, T. E. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)02002-6 · Cited by 1,656 · see citing works

Leptin

Ahima, R. S., & Flier, J. S. (2000) · Annual Review of Physiology · doi:10.1146/annurev.physiol.62.1.413 · Cited by 1,428 · see citing works

Apelin, a Newly Identified Adipokine Up-Regulated by Insulin and Obesity

Boucher, J., Masri, B., Daviaud, D., Gesta, S., Guigné, C., Mazzucotelli, A., Castan-Laurell, I., Tack, I., Knibiehler, B., Carpéné, C., et al. (2005) · Endocrinology · doi:10.1210/en.2004-1427 · Cited by 910 · see citing works

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

Tatemoto, K., Takayama, K., Zou, M.-X., Kumaki, I., Zhang, W. Y., KUMANO, K., & Fujimiya, M. (2001) · Regulatory Peptides · doi:10.1016/s0167-0115(01)00236-1 · Cited by 640 · see citing works

Molecular properties of apelin: tissue distribution and receptor binding

Kawamata, Y., Habata, Y., Fukusumi, S., Hosoya, M., Fujii, R., Hinuma, S., Nishizawa, N., Kitada, C., Onda, H., Nishimura, O., et al. (2001) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(00)00143-9 · Cited by 521 · see citing works

Bariatric surgery and long-term control of morbid obesity

Brolin, R. E. (2002) · JAMA · doi:10.1001/jama.288.22.2793 · Cited by 474 · see citing works

The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin

Edwards, C., Abusnana, S., Sunter, D., Murphy, K. G., Ghatei, M. A., & Bloom, S. R. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.160r007 · Cited by 433 · see citing works

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

Habata, Y., Fujii, R., Hosoya, M., Fukusumi, S., Kawamata, Y., Hinuma, S., Kitada, C., Nishizawa, N., Murosaki, S., Kurokawa, T., et al. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(99)00114-7 · Cited by 359 · see citing works

Novel Role for the Potent Endogenous Inotrope Apelin in Human Cardiac Dysfunction

Chen, M. M., Ashley, E. A., Deng, D. X.-F., Tsalenko, A., Deng, A. C., Tabibiazar, R., Ben‐Dor, A., Fenster, B. E., Yang, E., King, J. Y., et al. (2003) · Circulation · doi:10.1161/01.cir.0000091235.94914.75 · Cited by 349 · see citing works

A selective orexin-1 receptor antagonist reduces food consumption in male and female rats

Haynes, A. C., Jackson, B., Chapman, H., Tadayyon, M., Johns, A., Porter, R. A., & Arch, J. R. S. (2000) · Regulatory Peptides · doi:10.1016/s0167-0115(00)00199-3 · Cited by 338 · see citing works

Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues

O’Carroll, A., Selby, T. L., Palkovits, M., & Lolait, S. J. (2000) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(00)00072-5 · Cited by 338 · see citing works

Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action1This study was presented in part at the 28th Annual Meeting of the Society for Neuroscience, Los Angeles, CA, in November 1998.1

Dube, M. G., Kalra, S. P., & Kalra, P. S. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01824-7 · Cited by 335 · see citing works

Orexin A but Not Orexin B Rapidly Enters Brain from Blood by Simple Diffusion

Kastin, A. J., & Akerstrom, V. L. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38126-1 · Cited by 325 · see citing works

Independent Feeding and Metabolic Actions of Orexins in Mice

Lubkin, M., & Stricker‐Krongrad, A. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9750 · Cited by 325 · see citing works

Orexin Synthesis and Response in the Gut

Kirchgessner, A. L., & Liu, M.-T. (1999) · Neuron · doi:10.1016/s0896-6273(00)81041-7 · Cited by 320 · see citing works

The Effects of Centrally Administered Apelin-13 on Food Intake, Water Intake and Pituitary Hormone Release in Rats

Taheri, S., Murphy, K. G., Cohen, M., Sujkovic, E., Kennedy, A., Dhillo, W. S., Dakin, C. L., Sajedi, A., Ghatei, M., & Bloom, S. R. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6575 · Cited by 314 · see citing works

Functions of the orexinergic/hypocretinergic system

Kukkonen, J. P., Holmqvist, T., Ammoun, S., & Åkerman, K. E. O. (2002) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00055.2002 · Cited by 275 · see citing works

Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure

Földes, G., Horkay, F., Szokodi, I., Vuolteenaho, O. J., Ilves, M., Lindstedt, K. A., Mäyränpää, M. I., Sármán, B., Seres, L., Skoumal, R., et al. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)01424-4 · Cited by 260 · see citing works

Cloning, Pharmacological Characterization and Brain Distribution of the Rat Apelin Receptor

Mota, N. D., Lenkei, Z., & Llorens‐Cortés, C. (2000) · Neuroendocrinology · doi:10.1159/000054609 · Cited by 214 · see citing works

Inhibition of Food Intake by Central Injection of Anti-orexin Antibody in Fasted Rats

Yamada, H., Okumura, T., Motomura, W., Kobayashi, Y., & Kohgo, Y. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1998 · Cited by 187 · see citing works

Physiological Roles of the Leptin Endocrine System: Differences between Mice and Humans

Himms‐Hagen, J. (1999) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408369991239259 · Cited by 165 · see citing works

Intracerebroventricular injection of apelin-13 reduces food intake in the rat

Sunter, D., Hewson, A. K., & Dickson, S. L. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(03)00351-3 · Cited by 157 · see citing works

Long-term Results, Late Complications and Quality of Life in a Series of Adjustable Gastric Banding

Martikainen, T., Pirinen, E., Alhava, E. M., Poikolainen, E., Pääkkönen, M. E., Uusitupa, M. I. J., & Gylling, H. K. (2004) · Obesity Surgery · doi:10.1381/096089204323093435 · Cited by 136 · see citing works

Decreased plasma orexin-A levels in obese individuals

Adam, J. A., Menheere, P. P. C. A., van Dielen, F., Soeters, P. B., Buurman, W. A., & Greve, J.-W. M. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0801868 · Cited by 134 · see citing works

Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans

Burdyga, G., Lal, S., Spiller, D. G., Jiang, W. Y., Thompson, D. G., Attwood, S. E., Saeed, S. R., Grundy, D., Varró, A., Dimaline, R., et al. (2003) · Gastroenterology · doi:10.1053/gast.2003.50020 · Cited by 107 · see citing works

Sleep, sleep disorders and hypocretin (orexin)

Mignot, E. J.-M. (2004) · Sleep Medicine · doi:10.1016/s1389-9457(04)90001-9 · Cited by 99 · see citing works

Apelin expression in normal human tissues.

Falco, M. D., Luca, L. D., Onori, N., et al. (2003) · PubMed · Cited by 99 · see citing works

Dynamic regulation of leptin entry into brain by the blood–brain barrier

Kastin, A. J., & Pan, W. (2000) · Regulatory Peptides · doi:10.1016/s0167-0115(00)00147-6 · Cited by 96 · see citing works

Inhibitory Effect of Apelin-12 on Nocturnal Food Intake in the Rat

O’Shea, M. F., Hansen, M. J., Tatemoto, K., & Morris, M. J. (2003) · Nutritional Neuroscience · doi:10.1080/1028415031000111273 · Cited by 96 · see citing works

Orexin-A and leptin change inversely in fasting non-obese subjects

Komaki, G., Matsumoto, Y., Nishikata, H., et al. (2001) · European Journal of Endocrinology · doi:10.1530/eje.0.1440645 · Cited by 96 · see citing works

Inhibitory Effect of Exogenous Orexin A on Gastric Emptying, Plasma Leptin, and the Distribution of Orexin and Orexin Receptors in the Gut and Pancreas in Man

Ehrström, M., Gustafsson, T. P., Finn, A., Kirchgessner, A. L., Grybäck, P., Jacobsson, H., Hellström, P. M., & Näslund, E. B. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1408 · Cited by 93 · see citing works

Plasma orexin-A is lower in patients with narcolepsy

Higuchi, S., Usui, A., Murasaki, M., Matsushita, S., Nishioka, N., Yoshino, A., Matsui, T., Muraoka, H., Ishizuka, Y., Kanba, S., et al. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(01)02476-4 · Cited by 83 · see citing works

The Role of Leptin in Regulating Neuroendocrine Function in Humans

Blüher, S., & Mantzoros, C. S. (2004) · Journal of Nutrition · doi:10.1093/jn/134.9.2469s · Cited by 72 · see citing works

SURGERY FOR THE MORBIDLY OBESE PATIENT

Editorial Office (1999) · Obesity Surgery · doi:10.1381/096089299765553575 · Cited by 68 · see citing works

Decreased Plasma Levels of Orexin-A in Sleep Apnea

Busquets, X., Barbé, F., Barceló, A., et al. (2004) · Respiration · doi:10.1159/000081757 · Cited by 67 · see citing works

Serum Leptin Levels After Bariatric Surgery Across a Range of Glucose Tolerance from Normal to Diabetes

Geloneze, B., Tambascia, M. A., Repetto, E., Pereira, S. G., Pareja, J. C., & Magna, L. A. (2001) · Obesity Surgery · doi:10.1381/09608920160558623 · Cited by 66 · see citing works

Plasma Orexin-A Levels in Obstructive Sleep Apnea-Hypopnea Syndrome

Igarashi, N., Tatsumi, K., Nakamura, A., et al. (2003) · CHEST Journal · doi:10.1378/chest.124.4.1381 · Cited by 61 · see citing works

Plasma orexin-A-like immunoreactivity in patients with sleep apnea hypopnea syndrome

Nishijima, T., Sakurai, S., Arihara, Z., et al. (2003) · Peptides · doi:10.1016/s0196-9781(03)00055-x · Cited by 53 · see citing works

Surgery for the Morbidly Obese Patient

Snyder, R. P. (1989) · AORN Journal · doi:10.1016/s0001-2092(07)62142-5 · Cited by 46 · see citing works

Effect of Significant Intermediate-term Weight Loss on Serum Leptin Levels and Body Composition in Severely Obese Subjects

Infanger, D., Baldinger, R., Branson, R., Barbier, T., Steffen, R., & Horber, F. (2003) · Obesity Surgery · doi:10.1381/096089203322618704 · Cited by 43 · see citing works

Plasma Concentrations of Orexins in Children

Tomasik, P., Spodaryk, M., & Sztefko, K. (2004) · Annals of Nutrition and Metabolism · doi:10.1159/000080453 · Cited by 34 · see citing works

Exogenous leptin inhibits the secretion of pancreatic juice via a duodenal CCK1-vagal-dependent mechanism in anaesthetized rats

Matyjek, R., Herzig, K., Kato, S., & Zabielski, R. (2003) · Regulatory Peptides · doi:10.1016/s0167-0115(03)00064-8 · Cited by 23 · see citing works

Brain/Gut Peptides in Fed and Fasted Rats*

ZHENG, B., Eng, J., & Yalow, R. S. (1987) · Endocrinology · doi:10.1210/endo-120-2-714 · Cited by 14 · see citing works

Establishment and Primary Application of a Highly‐Sensitive Orexin‐A Radioimmunoassay

Lin, J., Yan, G., Hao, X., et al. (2004) · Journal of Immunoassay and Immunochemistry · doi:10.1081/ias-120027225 · Cited by 6 · see citing works

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

Maury, E., & Brichard, S. M. (2010) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.07.031 · Cited by 1,026 · see citing works

Wearable sensors for monitoring the physiological and biochemical profile of the athlete

Seshadri, D. R., Li, R. T., Voos, J. E., Rowbottom, J. R., Alfes, C. M., Zorman, C. A., & Drummond, C. K. (2019) · npj Digital Medicine · doi:10.1038/s41746-019-0150-9 · Cited by 537 · see citing works

Adipokines: New potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

Recinella, L., Orlando, G., Ferrante, C., Chiavaroli, A., Brunetti, L., & Leone, S. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.578966 · Cited by 261 · see citing works

Obesity, pregnancy, inflammation, and vascular function

Denison, F. C., Roberts, K. A., Barr, S. M., & Norman, J. E. (2010) · Reproduction · doi:10.1530/rep-10-0074 · Cited by 221 · see citing works

Adipocytokines: a bridge connecting obesity and insulin resistance

Zhuang, X.-F., Zhao, M.-M., Weng, C.-L., & Sun, N.-L. (2009) · Medical Hypotheses · doi:10.1016/j.mehy.2009.05.036 · Cited by 41 · see citing works

Detection of Orexin A Neuropeptide in Biological Fluids Using a Zinc Oxide Field Effect Transistor

Hagen, J., Lyon, W., Chushak, Y., Tomczak, M., Naik, R., Stone, M., & Kelley-Loughnane, N. (2013) · ACS Chemical Neuroscience · doi:10.1021/cn300159e · Cited by 22 · see citing works

The role of leptin and hypothalamicneuropeptides in energy homeostasis: Update on leptin in obesity

Mantzoros, C. S. (2001) · Growth Hormone & IGF Research · doi:10.1016/s1096-6374(01)80014-9 · Cited by 27 · see citing works

Leptin signaling and its central role in energy homeostasis

Liu, Z., Xiao, T., & Liu, H. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1238528 · Cited by 78 · see citing works

The Role of Leptin in the Development of Energy Homeostatic Systems and the Maintenance of Body Weight

LeDuc, C. A., Skowronski, A. A., & ROSENBAUM, M. S. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.789519 · Cited by 26 · see citing works

Recent advances in understanding the role of leptin in energy homeostasis

Münzberg, H., Singh, P., Heymsfield, S. B., Yu, S., & Morrison, C. D. (2020) · F1000Research · doi:10.12688/f1000research.24260.1 · Cited by 47 · see citing works

Leptin

Ahima, R. S., & Flier, J. S. (2000) · Annual Review of Physiology · doi:10.1146/annurev.physiol.62.1.413 · Cited by 1,428 · see citing works