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Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells
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“The distribution of H3K27me3 regions is rather unique: 6162 out of 10,554 (58%) modified loci are solely found on chromosome X as a result of X chromosome inactivation (XCI) ( Heard, 2004 ), and the karyotype of hES3 cells used in this study is 46; X, X. XCI has also been observed in female H9 human ES cells (Hoffman…”
BackgroundActive Genes Are Tri-Methylated at K4 of Histone H3
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Self-citationHistone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin
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Metadata
- Authors
- Zhao, X. D., Han, X., Chew, J. L., Liu, J., Chiu, K. P., Choo, A., Orlov, Y. L., Sung, W.-K., Shahab, A., Kuznetsov, V. A., Bourque, G., Oh, S., Ruan, Y., Ng, H.-H., & Wei, C.-L.
- Venue
- Cell Stem Cell
- Publisher
- Elsevier BV
- Published
- 2007-09
- Volume
- 1
- Issue
- 3
- Pages
- 286-298
- ISSN
- 1875-9777 (ISSN-L)
- 1934-5909
- OpenAlex
- W2067563155
- Cited by
- 615
- References
- 11
- FWCI
- 21.55
- Type
- journal article
- Language
- en
- Open access
- bronze
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.