Mechanisms that Regulate Stem Cell Aging and Life Span

mTOR Signaling in Growth Control and Disease

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. M., Wright, W. E., Weinrich, S. L., & Shay, J. W. (1994) · Science · doi:10.1126/science.7605428 · Cited by 7,091 · cited 2×

Signal integration in the endoplasmic reticulum unfolded protein response

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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The senescence-associated secretory phenotype: the dark side of tumor suppression

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Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients

Locatelli, F., Fishbane, S. N., Block, G. A., & Macdougall, I. C. (2017) · American Journal of Nephrology · doi:10.1159/000455166 · Cited by 4,836

The DNA Damage Response: Making It Safe to Play with Knives

Ciccia, A., & Elledge, S. J. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.019 · Cited by 4,368

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

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A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Harrison, D. E., Strong, R., Sharp, Z. D., Nelson, J. F., Astle, C. M., Flurkey, K., Nadon, N. L., Wilkinson, J. E., Frenkel, K., Carter, C. S., et al. (2009) · Nature · doi:10.1038/nature08221 · Cited by 3,766

Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs

Moehrle, B., Nattamai, K., Brown, A., Florian, M. C., Ryan, M. A., Vogel, M., Bliederhaeuser, C., Soller, K., Prows, D. R., Abdollahi, A., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.11.030 · Cited by 63

The Roles of Mitochondrial Dysfunction and Reactive Oxygen Species in Aging and Senescence

Zia, A., Farkhondeh, T., Pourbagher‐Shahri, A. M., & Samarghandian, S. (2021) · Current Molecular Medicine · doi:10.2174/1566524021666210218112616 · Cited by 70

Emerging role of stem cell-derived extracellular microRNAs in age-associated human diseases and in different therapies of longevity

Ullah, M., Ng, N. N., Concepcion, W., & Thakor, A. S. (2019) · Ageing Research Reviews · doi:10.1016/j.arr.2019.100979 · Cited by 57

DNA Damage Response in Hematopoietic Stem Cell Ageing

Li, T., Zhou, Z., Ju, Z., & Wang, Z. (2016) · Genomics Proteomics & Bioinformatics · doi:10.1016/j.gpb.2016.04.002 · Cited by 56

Proteasome activation enhances stemness and lifespan of human mesenchymal stem cells

Καπετάνου, Μ., Chondrogianni, N., Petrakis, S., Koliakos, G., & Gonos, E. S. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.12.035 · Cited by 55

Adult human neural stem cell therapeutics: Current developmental status and prospect

Nam, H. (2015) · World Journal of Stem Cells · doi:10.4252/wjsc.v7.i1.126 · Cited by 59

Botryllus schlosseri, an emerging model for the study of aging, stem cells, and mechanisms of regeneration

Voskoboynik, A., & Weissman, I. L. (2014) · Invertebrate Reproduction & Development · doi:10.1080/07924259.2014.944673 · Cited by 54

Mitochondrial and Reactive Oxygen Species Signaling Coordinate Stem Cell Fate Decisions and Life Long Maintenance

Khacho, M., & Slack, R. S. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7228 · Cited by 54

Basal p53 expression is indispensable for mesenchymal stem cell integrity

Boregowda, S. V., Krishnappa, V., Strivelli, J., Haga, C. L., Booker, C. N., & Phinney, D. G. (2018) · Cell Death and Differentiation · doi:10.1038/s41418-017-0004-4 · Cited by 53

Oocyte stem cells: fact or fantasy?

Horan, C., & Williams, S. A. (2017) · Reproduction · doi:10.1530/rep-17-0008 · Cited by 51

Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue

Tomokiyo, A., Yoshida, S., Hamano, S., Hasegawa, D., Sugii, H., & Maeda, H. (2018) · Stem Cells International · doi:10.1155/2018/5450768 · Cited by 51

Delayed animal aging through the recovery of stem cell senescence by platelet rich plasma

Liu, H., Huang, C., Lin, T., Tsai, C.-Y., Chen, S.-Y. T., Liu, A., Chen, W.-H., Wei, H.-J., Wang, M.-F., Williams, D. F., et al. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.08.034 · Cited by 51

Characterization of Senescence of Human Adipose-Derived Stem Cells After Long-Term Expansion

Truong, N. C., Bui, K. H.-T., & Pham, P. V. (2018) · Advances in experimental medicine and biology · doi:10.1007/5584_2018_235 · Cited by 50

Senescence in Pulmonary Fibrosis: Between Aging and Exposure

Venosa, A. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.606462 · Cited by 51

TP53 in Acute Myeloid Leukemia: Molecular Aspects and Patterns of Mutation

George, B., Kantarjian, H. M., Baran, N., Krocker, J. D., & Rios, A. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910782 · Cited by 53

DNA damage and tissue repair: What we can learn from planaria

Barghouth, P. G., Thiruvalluvan, M., LeGro, M., & Oviedo, N. J. (2019) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2018.04.013 · Cited by 48

Bone Marrow Immune Microenvironment in Myelodysplastic Syndromes

Kouroukli, O., Symeonidis, A. S., Foukas, P. G., Maragkou, M., & Kourea, E. P. (2022) · Cancers · doi:10.3390/cancers14225656 · Cited by 52

Molecular mechanisms of ageing and related diseases

Liu, J. (2014) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12247 · Cited by 50

Anatomy of the olfactory mucosa

Salazar, I., Sánchez‐Quinteiro, P., Barrios, A. W., Amado, M. L., & Vega, J. A. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-63855-7.00004-6 · Cited by 47

In Vitro Follicular Activation and Stem Cell Therapy as a Novel Treatment Strategies in Diminished Ovarian Reserve and Primary Ovarian Insufficiency

Fàbregues, F., Ferreri, J., Méndez, M., Calafell, J. M., Otero, J., & Farré, R. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.617704 · Cited by 45

Stem Cells Seen Through the FOXO Lens: An Evolving Paradigm

Liang, R. H.-S., & Ghaffari, S. (2018) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2017.11.006 · Cited by 45

Construct validity of PROMIS® Cognitive Function in cancer patients and noncancer controls.

Valentine, T. R., Weiss, D. M., Jones, J. A., & Andersen, B. L. (2019) · Health Psychology · doi:10.1037/hea0000693 · Cited by 44

Oxidative Stress Down-Regulates MiR-20b-5p, MiR-106a-5p and E2F1 Expression to Suppress the G1/S Transition of the Cell Cycle in Multipotent Stromal Cells

Tai, L., Huang, C.-J., Choo, K., Cheong, S. K., & Kamarul, T. (2020) · International Journal of Medical Sciences · doi:10.7150/ijms.38832 · Cited by 43

Neural Stem Cell Activation and the Role of Protein Synthesis

Baser, A., Skabkin, M. A., & Martín-Villalba, A. (2017) · Brain Plasticity · doi:10.3233/bpl-160038 · Cited by 43

Human gingival mesenchymal stem cells retain their growth and immunomodulatory characteristics independent of donor age

Dave, J. R., Chandekar, S. S., Behera, S., Desai, K. U., Salve, P. M., Sapkal, N. B., Mhaske, S. T., Dewle, A. M., Pokare, P. S., Page, M., et al. (2022) · Science Advances · doi:10.1126/sciadv.abm6504 · Cited by 43

Iron homeostasis and neurodegeneration in the ageing brain: Insight into ferroptosis pathways

Alrouji, M., Anwar, S., Venkatesan, K., Shahwan, M. J., Hassan, M. I., Islam, A., & Shamsi, A. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102575 · Cited by 45

Ovarian germline stem cells

Dunlop, C. E., Telfer, E. E., & Anderson, R. A. (2014) · Stem Cell Research & Therapy · doi:10.1186/scrt487 · Cited by 42

Vitamin C-Induced Epigenetic Modifications in Donor NSCs Establish Midbrain Marker Expressions Critical for Cell-Based Therapy in Parkinson's Disease

Wulansari, N., Kim, E.-H., Sulistio, Y. A., Rhee, Y.-H., Song, J., & Lee, S.-H. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.08.017 · Cited by 36

Stem Cell Aging and Sex: Are We Missing Something?

Dulken, B. W., & Brunet, A. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.05.006 · Cited by 41

Effects of senescent lens epithelial cells on the severity of age-related cortical cataract in humans

Fu, Q., Qin, Z., Yu, J., Yu, Y., Tang, Q., Lyu, D., Zhang, L., Chen, Z., & Yao, K. (2016) · Medicine · doi:10.1097/md.0000000000003869 · Cited by 42

DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation

Ma, X., Han, Y., Song, X., Do, T., Yang, Z., Ni, J., & Xie, T. (2016) · Development · doi:10.1242/dev.141069 · Cited by 39

Epigenetics of hematopoietic stem cell aging and disease

Oshima, M., & Iwama, A. (2014) · International Journal of Hematology · doi:10.1007/s12185-014-1647-2 · Cited by 39

Mitochondrial pyruvate carrier function in health and disease across the lifespan

Buchanan, J., & Taylor, E. (2020) · Biomolecules · doi:10.3390/biom10081162 · Cited by 40

A robust transcriptional program in newts undergoing multiple events of lens regeneration throughout their lifespan

Sousounis, K., Qi, F., Yadav, M., Millán, J. L., Toyama, F., Chiba, C., Eguchi, Y., Eguchi, G., & Tsonis, P. A. (2015) · eLife · doi:10.7554/elife.09594 · Cited by 41

A quantitative analysis of stem cell homeostasis in the Arabidopsis columella root cap

Hong, J. H., Chu, H., Zhang, C., Ghosh, D., Gong, X., & Xu, J. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00206 · Cited by 38

Ovarian Stem Cell Nests in Reproduction and Ovarian Aging

Ye, H., Zheng, T., Li, W., Li, X., Fu, X., Huang, Y.-Q., Hu, C., Li, J., Huang, J., Liu, Z., et al. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000484114 · Cited by 38

Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline

Lupo, G., Nisi, P. S., Esteve, P., Paul, Y., Novo, C. L., Sidders, B. S., Khan, M. A., Biagioni, S., Liu, H., Bovolenta, P., et al. (2018) · Aging Cell · doi:10.1111/acel.12745 · Cited by 35

Adult Cardiac Stem Cell Aging: A Reversible Stochastic Phenomenon?

Cianflone, E., Torella, M., Chimenti, C., Angelis, A. D., Beltrami, A. P., Urbanek, K., Rota, M., & Torella, D. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/5813147 · Cited by 40

Age-Related Changes in Bone-Marrow Mesenchymal Stem Cells

Babenko, V. A., Silachev, D. N., Danilina, T. I., Goryunov, K. V., Pevzner, I. B., Zorova, L. D., Popkov, V. A., Chernikov, V. P., Plotnikov, E. Y., Sukhikh, G. T., et al. (2021) · Cells · doi:10.3390/cells10061273 · Cited by 39

Metabolic syndrome alters expression of insulin signaling-related genes in swine mesenchymal stem cells

Conley, S. M., Zhu, X.-Y., Eirin, A., Tang, H. J., Lerman, A., van Wijnen, A. J., & Lerman, L. O. (2017) · Gene · doi:10.1016/j.gene.2017.10.086 · Cited by 37

Stem Cells as Vehicles for Youthful Regeneration of Aged Tissues

Rando, T. A., & Wyss‐Coray, T. (2014) · The Journals of Gerontology Series A · doi:10.1093/gerona/glu043 · Cited by 34

Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence

Li, R., Liu, Y., Xie, J., Huang, X., Zhang, L., Liu, H., & Li, L. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.02.005 · Cited by 36

HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy

Kim, C., Park, J., Song, Y., Kim, S., & Moon, J. (2019) · Aging Cell · doi:10.1111/acel.12909 · Cited by 36

Mobilization‐based transplantation of young‐donor hematopoietic stem cells extends lifespan in mice

Guderyon, M. J., Chen, C., Bhattacharjee, A., Ge, G., Fernandez, R. A., Gelfond, J., Gorena, K. M., Cheng, C. J. A., Li, Y., Nelson, J. F., et al. (2020) · Aging Cell · doi:10.1111/acel.13110 · Cited by 37

Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice

Jackson, H. W., Waterhouse, P. D., Sinha, A., Kislinger, T., Berman, H. K., & Khokha, R. (2015) · Nature Cell Biology · doi:10.1038/ncb3118 · Cited by 34

Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation

Nurković, J., Volarević, V., Lako, M., Armstrong, L., Arsenijević, N., & Stojković, M. (2015) · Rejuvenation Research · doi:10.1089/rej.2015.1676 · Cited by 34

Programmed ageing: decline of stem cell renewal, immunosenescence, and Alzheimer's disease

Lathe, R., & Clair, D. S. (2023) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12959 · Cited by 37

The systemic milieu as a mediator of dietary influence on stem cell function during ageing

Murphy, T., & Thuret, S. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.11.004 · Cited by 34

Why stem/progenitor cells lose their regenerative potential

Picerno, A., Stasi, A., Franzin, R., Curci, C., di Bari, I., Gesualdo, L., & Sallustio, F. (2021) · World Journal of Stem Cells · doi:10.4252/wjsc.v13.i11.1714 · Cited by 35

Mitochondrial Aging in the CNS: Unravelling Implications for Neurological Health and Disease

Steffan, D., Pezzini, C., Esposito, M., & Franco‐Romero, A. (2025) · Biomolecules · doi:10.3390/biom15091252 · Cited by 37

Adult stem cells in neural repair: Current options, limitations and perspectives

Mariano, E. D. (2015) · World Journal of Stem Cells · doi:10.4252/wjsc.v7.i2.477 · Cited by 31

Nicotinamide mononucleotide attenuates glucocorticoid‑induced osteogenic inhibition by regulating the SIRT1/PGC‑1α signaling pathway

Huang, R., & Tao, J. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11116 · Cited by 32

Sirtuins in Hematological Aging and Malignancy

Roth, M., Wang, Z., & Chen, W. (2013) · Critical Reviews™ in Oncogenesis · doi:10.1615/critrevoncog.2013010187 · Cited by 31

Cav-1 deletion impaired hematopoietic stem cell function

Bai, L., Shi, G., Zhang, L., Guan, F., Ma, Y., Li, Q., Cong, Y.-S., & Zhang, L. (2014) · Cell Death and Disease · doi:10.1038/cddis.2014.105 · Cited by 31

scDiffCom: a tool for differential analysis of cell–cell interactions provides a mouse atlas of aging changes in intercellular communication

Lagger, C., Ursu, E., Equey, A., Avelar, R. A., Pisco, A. O., Tăcutu, R., & de Magalhães, J. P. (2023) · Nature Aging · doi:10.1038/s43587-023-00514-x · Cited by 36

NAD + supplementation prevents STING‐induced senescence in CD8 + T cells by improving mitochondrial homeostasis

Ye, B., Pei, Y., Wang, L., Meng, D., Zhang, Y., Zou, S., Li, H., Liu, J., Xie, Z., Tian, C., et al. (2024) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30522 · Cited by 33

Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging

Li, Q., Ma, Y., Zhu, Y., Zhang, T., & Zhou, Y. (2016) · Journal of Periodontology · doi:10.1902/jop.2016.160338 · Cited by 29

Asymmetric inheritance of spindle microtubule-organizing centres preserves replicative lifespan

Manzano‐Lopez, J., Matellán, L. P., Álvarez-Llamas, A., Blanco-Mira, J. C., & Monje-Casas, F. (2019) · Nature Cell Biology · doi:10.1038/s41556-019-0364-8 · Cited by 33

Distinct types of stem cell divisions determine organ regeneration and aging in hair follicles

Matsumura, H., Liu, N., Nanba, D., Ichinose, S., Takada, A., Kurata, S., Morinaga, H., Mohri, Y., Arcangelis, A. D., Ohno, S., et al. (2021) · Nature Aging · doi:10.1038/s43587-021-00033-7 · Cited by 32

Preterm Cord Blood Contains a Higher Proportion of Immature Hematopoietic Progenitors Compared to Term Samples

Podestà, M., Bruschettini, M., Cossu, C., Sabatini, F., Dagnino, M., Romantsik, O., Spaggiari, G. M., Ramenghi, L. A., & Frassoni, F. (2015) · PLoS ONE · doi:10.1371/journal.pone.0138680 · Cited by 30

p53 and its mutants on the slippery road from stemness to carcinogenesis

Molchadsky, A., & Rotter, V. (2017) · Carcinogenesis · doi:10.1093/carcin/bgw092 · Cited by 30

Concise Review: Conceptualizing Paralogous Stem-Cell Niches and Unfolding Bone Marrow Progenitor Cell Identities

Chen, K. G., Johnson, K. R., McKay, R. D. G., & Robey, P. G. (2017) · Stem Cells · doi:10.1002/stem.2711 · Cited by 29

Hematopoietic stem cell regulation by the proteostasis network

Chua, B. A., & Signer, R. A. J. (2020) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000591 · Cited by 30

Recombinant HSP70 and mild heat shock stimulate growth of aged mesenchymal stem cells

Andreeva, N. V., Zatsepina, O. G., Garbuz, D. G., Evgen’ev, M. B., & Belyavsky, A. V. (2016) · Cell Stress and Chaperones · doi:10.1007/s12192-016-0691-7 · Cited by 29

The role of aging in cancer

Havas, A. P., Yin, S., & Adams, P. D. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13302 · Cited by 32

Somatic Cells with a Heavy Mitochondrial DNA Mutational Load Render Induced Pluripotent Stem Cells with Distinct Differentiation Defects

Wahlestedt, M., Ameur, A., Moraghebi, R., Norddahl, G. L., Sten, G., Woods, N., & Bryder, D. (2014) · Stem Cells · doi:10.1002/stem.1630 · Cited by 29

Senescence Effects of Angelica sinensis Polysaccharides on Human Acute Myelogenous Leukemia Stem and Progenitor Cells

Liu, J., Xu, C., Cai, S., Zhou, Y., Li, J., Jiang, R., & Wang, Y. (2013) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2013.14.11.6549 · Cited by 27

The intrinsic proteostasis network of stem cells

Llamas, E., Alirzayeva, H., Loureiro, R., & Vílchez, D. (2020) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2020.08.005 · Cited by 24

Mitochondrial Dynamics in Brain Cells During Normal and Pathological Aging

Sukhorukov, V. S., Baranich, T. I., Egorova, A. V., Akateva, A. V., Okulova, K. M., Ryabova, M. S., Skvortsova, K. A., Dmitriev, O. V., Mudzhiri, N. M., Воронков, Д. Н., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312855 · Cited by 27

Energy Metabolism and Metabolic Sensors in Stem Cells: The Metabostem Crossroads of Aging and Cancer

Menéndez, J. A., & Joven, J. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-07320-0_10 · Cited by 27

Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells

Tousian, H., Razavi, B. M., & Hosseinzadeh, H. (2019) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-019-00305-z · Cited by 26

Injury in aged animals robustly activates quiescent olfactory neural stem cells

Brann, J. H., Ellis, D. P., Ku, B. S., Spinazzi, E. F., & Firestein, S. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00367 · Cited by 26

Chemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia

Tang, C. S., Li, M., Chen, Y., Sun, H., Liu, S.-L., Zheng, W., Zhang, M., Li, H., Fu, W. E., Zhang, W., et al. (2018) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-018-0859-3 · Cited by 27

Opposing Action of Hedgehog and Insulin Signaling Balances Proliferation and Autophagy to Determine Follicle Stem Cell Lifespan

Singh, T., Lee, E. H., Hartman, T. R., Ruiz-Whalen, D. M., & O’Reilly, A. M. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.08.008 · Cited by 26

Caloric restriction and aging stem cells: The stick and the carrot?

Mazzoccoli, G., Tevy, M. F., Borghesan, M., Vergini, M. R. D., & Vinciguerra, M. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2013.10.014 · Cited by 28

Drug-induced premature senescence model in human dental follicle stem cells

Zhai, Y., Wei, R., Liu, J., Wang, H., Cai, W., Zhao, M., Hu, Y., Wang, S., Yang, T., Liu, X., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.14085 · Cited by 26

Cohesin controls intestinal stem cell identity by maintaining association of Escargot with target promoters

Khaminets, A., Ronnen-Oron, T., Baldauf, M., Meier, E., & Jasper, H. (2020) · eLife · doi:10.7554/elife.48160 · Cited by 22

Regulation of stem/progenitor cell maintenance by BMP5 in prostate homeostasis and cancer initiation

Tremblay, M. R., Viala, S., Shafer, M. E. R., Graham-Paquin, A.-L., Liu, C., & Bouchard, M. (2020) · eLife · doi:10.7554/elife.54542 · Cited by 23

The tumor suppression theory of aging

Wolf, A. M. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111583 · Cited by 27

Isolating Intestinal Stem Cells from Adult Drosophila Midguts by FACS to Study Stem Cell Behavior During Aging

Tauc, H. M., Tasdogan, A., & Pandur, P. (2014) · Journal of Visualized Experiments · doi:10.3791/52223 · Cited by 24

Redox Signaling in Cardiac Renewal

Kimura, W., Muralidhar, S. A., Canseco, D. C., Puente, B. N., Zhang, C. C., Xiao, F., Abderrahman, Y., & Sadek, H. A. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.6029 · Cited by 24

The cell cycle regulator protein P16 and the cellular senescence of dental follicle cells

Morsczeck, C. O., Hullmann, M. M., Reck, A., & Reichert, T. E. (2017) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-017-3134-6 · Cited by 24

3-D Cell Culture Systems in Bone Marrow Tissue and Organoid Engineering, and BM Phantoms as In Vitro Models of Hematological Cancer Therapeutics—A Review

Janagama, D. G., & Hui, S. K. (2020) · Materials · doi:10.3390/ma13245609 · Cited by 22

A state-of-the-art review on the MicroRNAs roles in hematopoietic stem cell aging and longevity

Ortiz, G. G. R., Mohammadi, Y., Nazari, A., Ataeinaeini, M., Kazemi, P., Yasamineh, S., Al-Naqeeb, B. Z. T., Zaidan, H. K., & Gholizadeh, O. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01117-0 · Cited by 25

Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease

Wang, X., Dong, C., Sun, L., Zhu, L., Sun, C., Ma, R., Ning, K., Lu, B., Zhang, J., & Xu, J. (2016) · Scientific Reports · doi:10.1038/srep37443 · Cited by 23

Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells

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New mechanisms driving muscle stem cell regenerative decline with aging

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