Sleep Disorders in dogs: A Pathophysiological and Clinical Review

Mondino, Alejandra; Delucchi, Luis; Moeser, Adam; Cerdá-González, Sofía; Vanini, Giancarlo

doi:10.1016/j.tcam.2021.100516

Cited by 24Sleep and Wakefulness ResearchSleep and related disordersVeterinary Medicine and Surgery

Sleep Disorders in dogs: A Pathophysiological and Clinical Review

Mondino, Alejandra, Delucchi, Luis, Moeser, Adam, Cerdá-González, Sofía, Vanini, Giancarlo·2021·Topics in Companion Animal Medicine

DOI 10.1016/j.tcam.2021.100516

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Abstract

Sleep is a fundamental process in mammals, including domestic dogs. Disturbances in sleep affect physiological functions like cognitive and physical performance, immune response, pain sensation and increase the risk of diseases. In dogs, sleep can be affected by several conditions, with narcolepsy, REM sleep behavior disorder and sleep breathing disorders being the most frequent causes. Furthermore, sleep disturbances can be a symptom of other primary diseases where they can contribute to the worsening of clinical signs. This review describes reciprocally interacting sleep and wakefulness promoting systems and how their dysfunction can explain the pathophysiological mechanisms of sleep disorders. Additionally, this work discusses the clinical characteristics, diagnostic tools and available treatments for these disorders while highlighting areas in where further studies are needed so as to improve their treatment and prevention.

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Is episodic-like memory <i>like</i> episodic memory?
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Authors: Mondino, A., Delucchi, L., Moeser, A., Cerdá-González, S., & Vanini, G.
Affiliations: Universidad de la República de Uruguay (UY)
University of Michigan (US)
Corresponding author: Mondino, Alejandra
ORCID: Mondino, Alejandra
Delucchi, Luis
Moeser, Adam
Cerdá-González, Sofía
Vanini, Giancarlo
Venue: Topics in Companion Animal Medicine
Publisher: Elsevier BV
Published: 2021-06
Volume: 43
Pages: 100516
ISSN: 0882-0511 (ISSN-L)
1938-9736
DOI: 10.1016/j.tcam.2021.100516
OpenAlex: W3126315186
Cited by: 24
References: 171
Citations by year: 2026: 3 · 2025: 9 · 2024: 4 · 2023: 6 · 2022: 1 · 2021: 1
FWCI: 0.44
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Topics in companion animal medicine (publishedVersion)
PubMed (publishedVersion)
Funders: University of California, Los Angeles
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Health Sciences › Veterinary › Small Animals › Veterinary Medicine and Surgery
Keywords: dogs, narcolepsy, REM sleep behavior disorder, sleep apnea, sleep-wake regulation, pathophysiology, clinical signs, diagnosis, treatment, immune response, pain sensation
MeSH terms: Animals, Dog Diseases, Dogs, Narcolepsy, Sleep, Sleep Wake Disorders, Wakefulness, REM Sleep Behavior Disorder

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Sleep Disorders in dogs: A Pathophysiological and Clinical Review

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