Endosomal and non-endosomal functions of ESCRT proteins
Abstract
The three endosomal sorting complexes required for transport (ESCRTs) are integral to the degradation of endocytosed membrane proteins and multivesicular body (MVB) biogenesis. Here, we review evidence that ESCRTs have evolved as a specialized machinery for the degradative sorting of ubiquitinated membrane proteins and we highlight recent studies that have shed light on the mechanisms by which these complexes mediate protein sorting, MVB biogenesis, tumour suppression and viral budding. We also discuss evidence that some ESCRT subunits have evolved additional functions that are unrelated to membrane trafficking.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
ILV formation requires two distinct processes: organization of the endosome membrane into tetraspanin-enriched microdomains (TEMs) and ESCRT complexes.
“Work in yeast [28-31] and other tissue culture models [32-34] suggests that ILV formation requires two distinct processes. The first involves the organization of the endosome membrane into specialized units highly enriched for a class of membrane proteins called tetraspanins [35].”
From Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies (2013) · cites this paper as [34]
Cites
Regulated portals of entry into the cell
Conner, S. D., & Schmid, S. L. (2003) · Nature · doi:10.1038/nature01451 · Cited by 3,816 · see citing works
Maxfield, F. R., & McGraw, T. E. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1315 · Cited by 1,716 · see citing works
Receptor downregulation and multivesicular-body sorting
Katzmann, D. J., Odorizzi, G., & Emr, S. D. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm973 · Cited by 1,201 · see citing works
The vacuolar (H+)-ATPases — nature's most versatile proton pumps
Nishi, T., & Forgac, M. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm729 · Cited by 1,197 · see citing works
Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins
Hicke, L., & Dunn, R. (2003) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.19.110701.154617 · Cited by 1,106 · see citing works
Babst, M., Katzmann, D. J., Estepa, E. J., Meerloo, T., & Emr, S. D. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00220-4 · Cited by 875 · see citing works
Hicke, L., Schubert, H., & Hill, C. P. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1701 · Cited by 795 · see citing works
The biogenesis of multivesicular endosomes
Gruenberg, J. E., & Stenmark, H. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1360 · Cited by 723 · see citing works
Self-citationHrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Raiborg, C., Bache, K. G., Gillooly, D. J., Madshus, I. H., Stang, E., & Stenmark, H. (2002) · Nature Cell Biology · doi:10.1038/ncb791 · Cited by 717 · see citing works
Self-citationRole of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
Matsuo, H., Chevallier, J., Mayran, N., Le Blanc, I., Ferguson, C., Fauré, J., Blanc, N. S., Matile, S., Dubochet, J., Sadoul, R., et al. (2004) · Science · doi:10.1126/science.1092425 · Cited by 705 · see citing works
Babst, M., Katzmann, D. J., Snyder, W. B., Wendland, B., & Emr, S. D. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00219-8 · Cited by 662 · see citing works
Morita, E., & Sundquist, W. I. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.102350 · Cited by 574 · see citing works
Demirov, D., & Freed, E. (2004) · Virus Research · doi:10.1016/j.virusres.2004.08.007 · Cited by 547 · see citing works
Not just a sink: endosomes in control of signal transduction
Miączyńska, M., Pelkmans, L., & Zerial, M. (2004) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2004.06.005 · Cited by 537 · see citing works
Protein sorting into multivesicular endosomes
Raiborg, C., Rusten, T. E., & Stenmark, H. (2003) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(03)00080-2 · Cited by 500 · see citing works
Self-citationHrs regulates multivesicular body formation via ESCRT recruitment to endosomes
Bache, K. G., Brech, A., Mehlum, A., & Stenmark, H. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302131 · Cited by 470 · see citing works
Self-citationVps27 recruits ESCRT machinery to endosomes during MVB sorting
Katzmann, D. J., Stefan, C. J., Babst, M., & Emr, S. D. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302136 · Cited by 455 · see citing works
Distinct monoubiquitin signals in receptor endocytosis
Haglund, K. (2003) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2003.09.005 · Cited by 444 · see citing works
Hrs Regulates Endosome Membrane Invagination and Tyrosine Kinase Receptor Signaling in Drosophila
Lloyd, T. E., Atkinson, R., Wu, M. N., Zhou, Y., Pennetta, G., & Bellen, H. J. (2002) · Cell · doi:10.1016/s0092-8674(02)00611-6 · Cited by 423 · see citing works
Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis
Shih, S. C., Katzmann, D. J., Schnell, J. D., Sutanto, M. A., Emr, S. D., & Hicke, L. (2002) · Nature Cell Biology · doi:10.1038/ncb790 · Cited by 418 · see citing works
Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
Marmor, M. D., & Yarden, Y. (2004) · Oncogene · doi:10.1038/sj.onc.1207390 · Cited by 382 · see citing works
Babst, M. (2005) · Traffic · doi:10.1111/j.1600-0854.2004.00246.x · Cited by 376 · see citing works
AMSH is an endosome-associated ubiquitin isopeptidase
McCullough, J., Clague, M. J., & Urbé, S. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200401141 · Cited by 369 · see citing works
Vaccari, T., & Bilder, D. H. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.09.019 · Cited by 365 · see citing works
Li, L.-M., & Cohen, S. N. (1996) · Cell · doi:10.1016/s0092-8674(00)81111-3 · Cited by 354 · see citing works
The Vps27p–Hse1p complex binds ubiquitin and mediates endosomal protein sorting
Bilodeau, P. S., Urbanowski, J. L., Winistorfer, S. C., & Piper, R. C. (2002) · Nature Cell Biology · doi:10.1038/ncb815 · Cited by 346 · see citing works
Determinants of caregiving experiences and mental health of partners of cancer patients
Nijboer, C., Triemstra, M., Tempelaar, R., Sanderman, R., & van den Bos, G. A. M. (1999) · Cancer · doi:10.1002/(sici)1097-0142(19990815)86:4 · Cited by 334 · see citing works
STAM and Hrs Are Subunits of a Multivalent Ubiquitin-binding Complex on Early Endosomes
Bache, K. G., Raiborg, C., Mehlum, A., & Stenmark, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210843200 · Cited by 324 · see citing works
Self-citationTumor Suppressor Properties of the ESCRT-II Complex Component Vps25 in Drosophila
Thompson, B. J., Mathieu, J., Sung, H.-H., Loeser, E., Rørth, P., & Cohen, S. M. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.09.020 · Cited by 322 · see citing works
TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation
Lu, Q., Hope, L. W., Brasch, M. A., Reinhard, C., & Cohen, S. N. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0932599100 · Cited by 319 · see citing works
Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae
Bowers, K., & Stevens, T. H. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2005.04.004 · Cited by 310 · see citing works
Amerik, A. Y., Nowak, J. A., Swaminathan, S., & Hochstrasser, M. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.10.3365 · Cited by 298 · see citing works
Moberg, K. H., Schelble, S., Burdick, S. K., & Hariharan, I. K. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.09.018 · Cited by 296 · see citing works
Brett, C. L., Tukaye, D. N., Mukherjee, S., & Rao, R. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-11-0999 · Cited by 294 · see citing works
Ubiquitin is part of the retrovirus budding machinery
Patnaik, A., Chau, V., & Wills, J. W. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.24.13069 · Cited by 292 · see citing works
Licata, J. M., Simpson-Holley, M., Wright, N., Han, Z.-Y., Paragas, J., & Harty, R. N. (2003) · Journal of Virology · doi:10.1128/jvi.77.3.1812-1819.2003 · Cited by 289 · see citing works
The Doa4 Deubiquitinating Enzyme Is Required for Ubiquitin Homeostasis in Yeast
Swaminathan, S., Amerik, A. Y., & Hochstrasser, M. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.8.2583 · Cited by 284 · see citing works
HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein
Pornillos, O., Higginson, D. S., Stray, K. M., Fisher, R. D., Garrus, J. E., Payne, M., He, G.-P., Wang, H. E., Morham, S. G., & Sundquist, W. I. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302138 · Cited by 258 · see citing works
ATPase-defective Mammalian VPS4 Localizes to Aberrant Endosomes and Impairs Cholesterol Trafficking
Bishop, N. E., & Woodman, P. G. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.1.227 · Cited by 250 · see citing works
Ubiquitin interactions of NZF zinc fingers
Alam, S. L., Sun, J., Payne, M., Welch, B. D., Blake, B. K., Davis, D. R., Meyer, H. H., Emr, S. D., & Sundquist, W. I. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600114 · Cited by 248 · see citing works
Teo, H., Gill, D. J., Sun, J., Perisic, O., Veprintsev, D. B., Vallis, Y., Emr, S. D., & Williams, R. L. (2006) · Cell · doi:10.1016/j.cell.2006.01.047 · Cited by 242 · see citing works
ESCRT-II, an Endosome-Associated Complex Required for Protein Sorting
Teo, H., Perišić, O., González, B., & Williams, R. L. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.09.003 · Cited by 238 · see citing works
Ubiquitin Recognition by the Human TSG101 Protein
Sundquist, W. I., Schubert, H., Kelly, B. N., Hill, G. C., Holton, J. M., & Hill, C. P. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00129-7 · Cited by 235 · see citing works
Interactions of GGA3 with the ubiquitin sorting machinery
Puertollano, R., & Bonifacino, J. S. (2004) · Nature Cell Biology · doi:10.1038/ncb1106 · Cited by 231 · see citing works
Structural and mechanistic studies of VPS4 proteins
Scott, A., Chung, H.-Y., Gonciarz-Swiatek, M., Hill, G. C., Whitby, F. G., Gaspar, J., Holton, J. M., Viswanathan, R., Ghaffarian, S., Hill, C. P., et al. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600818 · Cited by 218 · see citing works
Defective downregulation of receptor tyrosine kinases in cancer
Bache, K. G., Slagsvold, T., & Stenmark, H. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600292 · Cited by 213 · see citing works
Self-citationBro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae
Odorizzi, G., Katzmann, D. J., Babst, M., Audhya, A., & Emr, S. D. (2003) · Journal of Cell Science · doi:10.1242/jcs.00395 · Cited by 213 · see citing works
McCullough, J., Row, P. E., Lorenzo, Ó., Doherty, M. K., Beynon, R. J., Clague, M. J., & Urbé, S. (2006) · Current Biology · doi:10.1016/j.cub.2005.11.073 · Cited by 206 · see citing works
Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes
Luhtala, N., & Odorizzi, G. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200403139 · Cited by 201 · see citing works
Bilodeau, P. S., Winistorfer, S. C., Kearney, W. R., Robertson, A. D., & Piper, R. C. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200305007 · Cited by 193 · see citing works
Exploring the ESCRTing machinery in eukaryotes
Ibl, V., & Hauser, M. (2006) · Trends in Plant Science · doi:10.1016/j.tplants.2006.01.008 · Cited by 191 · see citing works
Bowers, K., Piper, S. C., Edeling, M. A., Gray, S. R., Owen, D. J., Lehner, P. J., & Luzio, J. P. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508632200 · Cited by 187 · see citing works
Eap45 in Mammalian ESCRT-II Binds Ubiquitin via a Phosphoinositide-interacting GLUE Domain
Slagsvold, T., Aasland, R., Hirano, S., Bache, K. G., Raiborg, C., Trambaiolo, D. M., Soichi Wakatsuki, A., & Stenmark, H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501510200 · Cited by 186 · see citing works
Self-citationStructure and ESCRT-III protein interactions of the MIT domain of human VPS4A
Scott, A., Gaspar, J., Stuchell‐Brereton, M. D., Alam, S. L., Skalicky, J. J., & Sundquist, W. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502165102 · Cited by 183 · see citing works
Structure of the ESCRT-II endosomal trafficking complex
Hierro, A., Sun, J., Rusnak, A. S., Kim, J., Prag, G., Emr, S. D., & Hurley, J. H. (2004) · Nature · doi:10.1038/nature02914 · Cited by 182 · see citing works
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Hirano, S., Kawasaki, M., Ura, H., Kato, R., Raiborg, C., Stenmark, H., & Soichi Wakatsuki, A. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1051 · Cited by 178 · see citing works
Self-citationThe Human Endosomal Sorting Complex Required for Transport (ESCRT-I) and Its Role in HIV-1 Budding
Stuchell‐Brereton, M. D., Garrus, J. E., Müller, B., Stray, K. M., Ghaffarian, S., McKinnon, R. S., Kräusslich, H., Morham, S. G., & Sundquist, W. I. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405226200 · Cited by 174 · see citing works
Bache, K. G., Stuffers, S., Malerød, L., Slagsvold, T., Raiborg, C., Lechardeur, D., Wälchli, S., Lukács, G. L., Brech, A., & Stenmark, H. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-10-0915 · Cited by 166 · see citing works
Self-citationWhitley, P. R., Reaves, B. J., Hashimoto, M., Riley, A. M., Potter, B. V. L., & Holman, G. D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306864200 · Cited by 160 · see citing works
A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control
Li, L., Liao, J., Ruland, J., Mak, T. W., & Cohen, S. N. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1619 · Cited by 159 · see citing works
Bache, K. G., Slagsvold, T., Cabezas, A., Rosendal, K. R., Raiborg, C., & Stenmark, H. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-03-0250 · Cited by 159 · see citing works
Self-citationDupré‐Crochet, S., & Haguenauer‐Tsapis, R. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.14.4482-4494.2001 · Cited by 156 · see citing works
Wirblich, C., Bhattacharya, B., & Roy, P. (2006) · Journal of Virology · doi:10.1128/jvi.80.1.460-473.2006 · Cited by 150 · see citing works
CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins
Howard, T. L., Stauffer, D. R., Degnin, C., & Hollenberg, S. M. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.13.2395 · Cited by 150 · see citing works
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus buddingPreprint
Amit, I., Yakir, L., Katz, M., Zwang, Y., Marmor, M. D., Citri, A., Shtiegman, K., Alroy, I., Tuvia, S., Reiss, Y., et al. (2004) · Genes & Development · doi:10.1101/gad.294904 · Cited by 148 · see citing works
p53 Accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101
Ruland, J., Sirard, C., Elia, A., MacPherson, D. P., Wakeham, A. C., Li, L., de la Pompa, J. L., Cohen, S. N., & Mak, T. W. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1859 · Cited by 145 · see citing works
Tsg101 Is Essential for Cell Growth, Proliferation, and Cell Survival of Embryonic and Adult Tissues
Wagner, K., Krempler, A., Qi, Y., Park, K.-R., Henry, M. D., Triplett, A. A., Riedlinger, G., Rucker, E. B., & Hennighausen, L. G. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.23.1.150-162.2003 · Cited by 132 · see citing works
Alix/AIP1 Antagonizes Epidermal Growth Factor Receptor Downregulation by the Cbl-SETA/CIN85 Complex
Schmidt, M. H. H., Hoeller, D., Yu, J., Furnari, F. B., Cavenee, W. K., Đikić, I., & Bögler, O. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.20.8981-8993.2004 · Cited by 121 · see citing works
Structural and Functional Organization of the ESCRT-I Trafficking Complex
Kostelansky, M. S., Sun, J., Lee, S., Kim, J., Ghirlando, R., Hierro, A., Emr, S. D., & Hurley, J. H. (2006) · Cell · doi:10.1016/j.cell.2006.01.049 · Cited by 115 · see citing works
Alix regulates cortical actin and the spatial distribution of endosomes
Cabezas, A., Bache, K. G., Brech, A., & Stenmark, H. (2005) · Journal of Cell Science · doi:10.1242/jcs.02382 · Cited by 113 · see citing works
Self-citationCHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression
Stauffer, D. R., Howard, T. L., Nyun, T., & Hollenberg, S. M. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.13.2383 · Cited by 112 · see citing works
Xie, W., Li, L., & Cohen, S. N. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.4.1595 · Cited by 105 · see citing works
Schmidt, M. H. H., Chen, B., Randazzo, L., & Bögler, O. (2003) · Journal of Cell Science · doi:10.1242/jcs.00522 · Cited by 104 · see citing works
Burgdorf, S., Leister, P., & Scheidtmann, K. H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313703200 · Cited by 97 · see citing works
Eastman, S. W., Martin‐Serrano, J., Chung, W., Zang, T. M., & Bieniasz, P. D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410384200 · Cited by 89 · see citing works
Mahul‐Mellier, A., Hemming, F. J., Blot, B., Fraboulet, S., & Sadoul, R. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3069-05.2006 · Cited by 86 · see citing works
Krempler, A., Henry, M., Triplett, A. A., & Wagner, K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207662200 · Cited by 86 · see citing works
Xu, Z., Liang, L., Wang, H., Li, T., & Zhao, M. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.10.109 · Cited by 82 · see citing works
Interactions of TOM1L1 with the Multivesicular Body Sorting Machinery
Puertollano, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m412481200 · Cited by 80 · see citing works
Feng, G. H., Lih, C., & Cohen, S. N. (2000) · PubMed · Cited by 64 · see citing works
Do Alix and ALG‐2 really control endosomes for better or for worse?
Sadoul, R. (2005) · Biology of the Cell · doi:10.1042/bc20050007 · Cited by 60 · see citing works
Equine Infectious Anemia Virus and the Ubiquitin-Proteasome System
Ott, D. E., Coren, L. V., Sowder, R. C., Adams, J., Nagashima, K., & Schubert, U. (2002) · Journal of Virology · doi:10.1128/jvi.76.6.3038-3044.2002 · Cited by 60 · see citing works
Carstens, M. J., Krempler, A., Triplett, A. A., van Lohuizen, M., & Wagner, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400408200 · Cited by 58 · see citing works
Reduction of TSG101 protein has a negative impact on tumor cell growth
Zhu, G., Gilchrist, R., Borley, N., Chng, H. W., Morgan, M. R., Marshall, J. F., Camplejohn, R. S., Muir, G., & Hart, I. R. (2004) · International Journal of Cancer · doi:10.1002/ijc.20014 · Cited by 56 · see citing works
Cloning and Characterization of ELL-associated Proteins EAP45 and EAP20
Kamura, T., Burian, D. M., Khalili, H., Schmidt, S. L., Sato, S., Liu, W.-J., Conrad, M. N., Conaway, R. C., Conaway, J. W., & Shilatifard, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010142200 · Cited by 53 · see citing works
Oh, H.-S., Mammucari, C., Nenci, A., Cabodi, S., Cohen, S. N., & Dotto, G. P. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082123999 · Cited by 52 · see citing works
Sevrioukov, E. A., Moghrabi, N., Kuhn, M., & Krämer, H. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-11-1013 · Cited by 51 · see citing works
Identification and Purification of the Holo-ELL Complex
Shilatifard, A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.18.11212 · Cited by 37 · see citing works
The Vif protein of human immunodeficiency virus type 1 is posttranslationally modified by ubiquitin
Dussart, S., Courcoul, M., Bessou, G., Douaisi, M. P., Duverger, Y., Vigne, R., & Decroly, É. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.01.023 · Cited by 32 · see citing works
Johnson, M. C., Spidel, J. L., Ako-adjei, D., Wills, J. W., & Vogt, V. M. (2005) · Journal of Virology · doi:10.1128/jvi.79.6.3775-3786.2005 · Cited by 24 · see citing works
Receptor tyrosine kinase and G‐protein coupled receptor signaling and sorting within endosomes
Grimes, M. L., & Miettinen, H. M. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01603.x · Cited by 23 · see citing works
Flagged first, then by citations
1 of the 92 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Lysosomes: fusion and function
Luzio, J. P., Pryor, P. R., & Bright, N. A. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2217 · Cited by 1,737 · see citing works
Pathways and mechanisms of endocytic recycling
Grant, B. D., & Donaldson, J. G. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2755 · Cited by 1,468 · see citing works
Akers, J. C., Gonda, D., Kim, R., Carter, B. S., & Chen, C. C. (2013) · Journal of Neuro-Oncology · doi:10.1007/s11060-013-1084-8 · Cited by 1,423 · see citing works
“Work in yeast [28–31] and other tissue culture models [32–34] suggests that ILV formation requires two distinct processes.”
Biogenesis and Function of Multivesicular Bodies
Piper, R. C., & Katzmann, D. J. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123319 · Cited by 771 · see citing works
Endocytosis and intracellular trafficking of ErbBs
Sorkin, A. D., & Goh, L. K. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.07.029 · Cited by 756 · see citing works
The emerging shape of the ESCRT machinery
Williams, R. L., & Urbé, S. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2162 · Cited by 747 · see citing works
Kraft, C., Deplazes, A., Sohrmann, M., & Peter, M. (2008) · Nature Cell Biology · doi:10.1038/ncb1723 · Cited by 733 · see citing works
Multivesicular Endosome Biogenesis in the Absence of ESCRTs
Stuffers, S., Wegner, C. S., Stenmark, H., & Brech, A. (2009) · Traffic · doi:10.1111/j.1600-0854.2009.00920.x · Cited by 731 · see citing works
Self-citationMembrane scission by the ESCRT-III complex
Wollert, T., Wunder, C., Lippincott‐Schwartz, J., & Hurley, J. H. (2009) · Nature · doi:10.1038/nature07836 · Cited by 634 · see citing works
Filimonenko, M., Stuffers, S., Raiborg, C., Yamamoto, A., Malerød, L., Fisher, E. M. C., Isaacs, A., Brech, A., Stenmark, H., & Simonsen, A. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200702115 · Cited by 626 · see citing works
Self-citationRegulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications
Hanyaloglu, A. C., & von Zastrow, M. (2007) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.48.113006.094830 · Cited by 610 · see citing works
Krämer‐Albers, E., Bretz, N. P., Tenzer, S., Winterstein, C., Möbius, W., Berger, H., Nave, K., Schild, H., & Trotter, J. (2007) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200700522 · Cited by 548 · see citing works
ESCRT complexes and the biogenesis of multivesicular bodies
Hurley, J. H. (2008) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.12.002 · Cited by 482 · see citing works
The dependence of viral RNA replication on co-opted host factors
Nagy, P. D., & Pogany, J. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2692 · Cited by 447 · see citing works
Plasma membrane deformation by circular arrays of ESCRT-III protein filaments
Hanson, P. I., Roth, R., Lin, Y., & Heuser, J. E. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200707031 · Cited by 427 · see citing works
Mycobacterium tuberculosis and the environment within the phagosome
Rohde, K. H., Yates, R. M., Purdy, G. E., & Russell, D. G. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2007.00547.x · Cited by 361 · see citing works
Teis, D., Saksena, S., & Emr, S. D. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.08.013 · Cited by 338 · see citing works
Hereditary spastic paraplegias: membrane traffic and the motor pathway
Blackstone, C. D., O’Kane, C. J., & Reid, E. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2946 · Cited by 311 · see citing works
Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4
Obita, T., Saksena, S., Ghazi-Tabatabai, S., Gill, D. J., Perišić, O., Emr, S. D., & Williams, R. L. (2007) · Nature · doi:10.1038/nature06171 · Cited by 311 · see citing works
ESCRTing proteins in the endocytic pathway
SAKSENA, S., Sun, J., Chu, T., & Emr, S. D. (2007) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2007.09.010 · Cited by 292 · see citing works
Traer, C. J., Rutherford, A. C., Palmer, K. J., Wassmer, T., Oakley, J. D., Attar, N., Carlton, J. G., Kremerskothen, J., Stephens, D. J., & Cullen, P. J. (2007) · Nature Cell Biology · doi:10.1038/ncb1656 · Cited by 260 · see citing works
Midbody Targeting of the ESCRT Machinery by a Noncanonical Coiled Coil in CEP55
Lee, H. H., Elia, N., Ghirlando, R., Lippincott‐Schwartz, J., & Hurley, J. H. (2008) · Science · doi:10.1126/science.1162042 · Cited by 260 · see citing works
Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion
Connell, J. W., Lindon, C., Luzio, J. P., & Reid, E. (2008) · Traffic · doi:10.1111/j.1600-0854.2008.00847.x · Cited by 243 · see citing works
Extracellular Vesicles as Signaling Mediators and Disease Biomarkers across Biological Barriers
Simeone, P., Bologna, G., Lanuti, P., Pierdomenico, L., Guagnano, M. T., Pieragostino, D., Boccio, P. D., Vergara, D., Marchisio, M., Miscia, S., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072514 · Cited by 213 · see citing works
Dynamic control of signaling by modular adaptor proteins
Pawson, T. J. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.02.013 · Cited by 205 · see citing works
Miranda, M., & Sorkin, A. D. (2007) · Molecular Interventions · doi:10.1124/mi.7.3.7 · Cited by 205 · see citing works
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutantsPreprint
Samuelson, A. V., Carr, C. E., & Ruvkun, G. (2007) · Genes & Development · doi:10.1101/gad.1588907 · Cited by 203 · see citing works
Intra-endosomal membrane traffic
van der Goot, F. G., & Grüenberg, J. (2006) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.08.003 · Cited by 196 · see citing works
Bhandari, D., Trejo, J., Benovic, J., & Marchese, A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705085200 · Cited by 196 · see citing works
More than one door – Budding of enveloped viruses through cellular membranes
Welsch, S., Müller, B., & Kräusslich, H. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.03.060 · Cited by 196 · see citing works
Sbrissa, D., Ikonomov, O. C., Fu, Z., Ijuin, T., Gruenberg, J. E., Takenawa, T., & Shisheva, A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611678200 · Cited by 193 · see citing works
A Unique Role for the Host ESCRT Proteins in Replication of Tomato bushy stunt virus
Barajas, D., Jiang, Y., & Nagy, P. D. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000705 · Cited by 189 · see citing works
Lambert, C., Döring, T., & Prange, R. (2007) · Journal of Virology · doi:10.1128/jvi.00479-07 · Cited by 183 · see citing works
PIKfyve: Partners, significance, debates and paradoxes
Shisheva, A. (2008) · Cell Biology International · doi:10.1016/j.cellbi.2008.01.006 · Cited by 177 · see citing works
Understanding Cytokinesis Failure
Normand, G., & King, R. W. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-6199-0_3 · Cited by 171 · see citing works
Molecular Architecture and Functional Model of the Complete Yeast ESCRT-I Heterotetramer
Kostelansky, M. S., Schluter, C., Tam, Y. Y. C., Lee, S., Ghirlando, R., Beach, B., Conibear, E., & Hurley, J. H. (2007) · Cell · doi:10.1016/j.cell.2007.03.016 · Cited by 172 · see citing works
Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes
Piper, R. C., & Luzio, J. P. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.07.002 · Cited by 161 · see citing works
Herpes Simplex Virus Type 1 Cytoplasmic Envelopment Requires Functional Vps4
Crump, C. M., Yates, C., & Minson, T. (2007) · Journal of Virology · doi:10.1128/jvi.00222-07 · Cited by 159 · see citing works
Structural basis for viral late-domain binding to Alix
Lee, S., Joshi, A., Nagashima, K., Freed, E. O., & Hurley, J. H. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1203 · Cited by 158 · see citing works
In Vitro Budding of Intralumenal Vesicles into Late Endosomes Is Regulated by Alix and Tsg101
Falguières, T., Luyet, P., Bissig, C., Scott, C. C., Velluz, M., & Gruenberg, J. E. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-03-0239 · Cited by 155 · see citing works
Morphogenesis of hepatitis B virus and its subviral envelope particles
Patient, R., Hourioux, C., & Roingeard, P. (2009) · Cellular Microbiology · doi:10.1111/j.1462-5822.2009.01363.x · Cited by 153 · see citing works
Structural insight into the ESCRT‐I/‐II link and its role in MVB trafficking
Gill, D. J., Teo, H., Sun, J., Perišić, O., Veprintsev, D. B., Emr, S. D., & Williams, R. L. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601501 · Cited by 150 · see citing works
Futter, C. E., & White, I. J. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00590.x · Cited by 150 · see citing works
Glozman, R., Okiyoneda, T., Mulvihill, C. M., Rini, J. M., Barrière, H., & Lukács, G. L. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200808124 · Cited by 149 · see citing works
Structure and Disassembly of Filaments Formed by the ESCRT-III Subunit Vps24
Ghazi-Tabatabai, S., Saksena, S., Short, J. M., Pobbati, A. V., Veprintsev, D. B., Crowther, R. A., Emr, S. D., Egelman, E. H., & Williams, R. L. (2008) · Structure · doi:10.1016/j.str.2008.06.010 · Cited by 144 · see citing works
Kim, B. Y., Olzmann, J. A., Barsh, G. S., Chin, L., & Li, L. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-09-0787 · Cited by 137 · see citing works
The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein
Hasegawa, T., Konno, M., Baba, T., Sugeno, N., Kikuchi, A., Kobayashi, M., Miura, E., Tanaka, N., Tamai, K., Furukawa, K., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0029460 · Cited by 136 · see citing works
Yu, F., Lou, L., Tian, M., Li, Q., Ding, Y., Cao, X., Wu, Y., Belda‐Palazón, B., Rodrı́guez, P. L., Yang, S., et al. (2016) · Molecular Plant · doi:10.1016/j.molp.2016.11.002 · Cited by 131 · see citing works
The regulation of the endosomal compartment by p53 the tumor suppressor gene
Yu, X., Riley, T., & Levine, A. J. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.06949.x · Cited by 130 · see citing works
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Raiborg, C., Malerød, L., Pedersen, N. M., & Stenmark, H. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.10.014 · Cited by 126 · see citing works
Self-citationCalistri, A., Sette, P., Salata, C., Cancellotti, E., Forghieri, C., Comin, A., Göttlinger, H. G., Campadelli‐Fiume, G., Palù, G., & Parolin, C. (2007) · Journal of Virology · doi:10.1128/jvi.01364-07 · Cited by 124 · see citing works
Novel Ist1-Did2 Complex Functions at a Late Step in Multivesicular Body Sorting
Rue, S. M., Mattei, S., Saksena, S., & Emr, S. D. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-07-0694 · Cited by 124 · see citing works
The ESCRT pathway and HIV-1 budding
Usami, Y., Popov, S. V., Popova, E. N., Inoue, M., Weissenhorn, W., & Göttlinger, H. G. (2009) · Biochemical Society Transactions · doi:10.1042/bst0370181 · Cited by 122 · see citing works
Barajas, D., de Castro, I. F., Pogany, J., Risco, C., & Nagy, P. D. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004087 · Cited by 120 · see citing works
Malerød, L., Stuffers, S., Brech, A., & Stenmark, H. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00630.x · Cited by 120 · see citing works
Self-citationSynergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal
Hori, K., Sen, A., Kirchhausen, T. L., & Artavanis‐Tsakonas, S. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201104146 · Cited by 116 · see citing works
Ramaseshadri, P., Segers, G. C., Flannagan, R. S., Wiggins, E., Clinton, W. P., Ilagan, O. M., McNulty, B. C., Clark, T. L., & Bolognesi, R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054270 · Cited by 115 · see citing works
Coulter, M. E., Dorobantu, C. M., Lodewijk, G. A., Delalande, F., Cianférani, S., Ganesh, V. S., Smith, R. S., Lim, E. T., Xu, C. S., Pang, S., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.06.100 · Cited by 106 · see citing works
RILP is required for the proper morphology and function of late endosomes
Progida, C., Malerød, L., Stuffers, S., Brech, A., Bucci, C., & Stenmark, H. (2007) · Journal of Cell Science · doi:10.1242/jcs.017301 · Cited by 111 · see citing works
Self-citationUsami, Y., Popov, S. V., Popova, E. N., & Göttlinger, H. G. (2008) · Journal of Virology · doi:10.1128/jvi.02675-07 · Cited by 110 · see citing works
Integrated Structural Model and Membrane Targeting Mechanism of the Human ESCRT-II Complex
Im, Y. J., & Hurley, J. H. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.04.004 · Cited by 105 · see citing works
The Clathrin Adaptor Complex AP-1 Binds HIV-1 and MLV Gag and Facilitates Their Budding
Camus, G., Segura-Morales, C., Molle, D., López‐Vergès, S., Begon‐Pescia, C., Cazevieille, C., Schu, P. V., Bertrand, É., Berlioz‐Torrent, C., & Basyuk, E. I. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-12-1147 · Cited by 103 · see citing works
Amiodarone Alters Late Endosomes and Inhibits SARS Coronavirus Infection at a Post-Endosomal Level
Stadler, K., Ha, H. R., Ciminale, V., Spirlı̀, C., Saletti, G., Schiavon, M., Bruttomesso, D., Bigler, L., Folláth, F., Pettenazzo, A., et al. (2008) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2007-0217oc · Cited by 99 · see citing works
Through the back door: Unconventional protein secretion
Cohen, M. J., Chirico, W. J., & Lipke, P. N. (2020) · The Cell Surface · doi:10.1016/j.tcsw.2020.100045 · Cited by 97 · see citing works
Moorman, N. J., Sharon-Friling, R., Shenk, T., & Cristea, I. M. (2010) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m900485-mcp200 · Cited by 97 · see citing works
Hrs and SNX3 Functions in Sorting and Membrane Invagination within Multivesicular Bodies
Pons, V., Luyet, P., Morel, É., Abrami, L., van der Goot, F. G., Parton, R. G., & Gruenberg, J. E. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060214 · Cited by 97 · see citing works
Mutation of SIMPLE in Charcot–Marie–Tooth 1C alters production of exosomes
Zhu, H., Guariglia, S. R., Yu, R. Y.-L., Li, W., Brancho, D., Peinado, H., Lyden, D. C., Salzer, J. L., Bennett, C. L., & Chow, C.-W. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e12-07-0544 · Cited by 97 · see citing works
Breaking up is hard to do – membrane traffic in cytokinesis
Prekeris, R., & Gould, G. W. (2008) · Journal of Cell Science · doi:10.1242/jcs.018770 · Cited by 94 · see citing works
Nagy, P. D., & Pogany, J. (2010) · Advances in virus research · doi:10.1016/s0065-3527(10)76004-8 · Cited by 91 · see citing works
A concentric circle model of multivesicular body cargo sorting
Nickerson, D. P., Russell, M. R. G., & Odorizzi, G. (2007) · EMBO Reports · doi:10.1038/sj.embor.7401004 · Cited by 91 · see citing works
Barajas, D., & Nagy, P. D. (2009) · Virology · doi:10.1016/j.virol.2009.11.010 · Cited by 89 · see citing works
Host factors mediating HIV-1 replication
Friedrich, B. M., Dziuba, N., Li, G., Endsley, M. A., Murray, J. L., & Ferguson, M. R. (2011) · Virus Research · doi:10.1016/j.virusres.2011.08.001 · Cited by 86 · see citing works
Endosomal clathrin drives actin accumulation at the immunological synapse
Calabia-Linares, C., Robles‐Valero, J., de la Fuente, H., Pérez‐Martínez, M., Martin-Cofreces, N. B., Alfonso-Pérez, M., Gutiérrez‐Vázquez, C., Mittelbrunn, M., Ibiza, S., Urbano-Olmos, F. R., et al. (2011) · Journal of Cell Science · doi:10.1242/jcs.078832 · Cited by 84 · see citing works
Haarer, B. K., Viggiano, S. C., Hibbs, M. A., Troyanskaya, O. G., & Amberg, D. C. (2006) · Genes & Development · doi:10.1101/gad.1477507 · Cited by 83 · see citing works
Endocytosis: A Positive or a Negative Influence on Wnt Signalling?
Gagliardi, M. E., Piddini, E., & Vincent, J. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00662.x · Cited by 81 · see citing works
Shibata, H., SUZUKI, H., Yoshida, H., & Maki, M. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.12.101 · Cited by 80 · see citing works
Fission of Tubular Endosomes Triggers Endosomal Acidification and Movement
Mesaki, K., Tanabe, K., Obayashi, M., Oe, N., & Takei, K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019764 · Cited by 78 · see citing works
Membrane Buckling Induced by Curved Filaments
Lenz, M., Crow, D. J. G., & Joanny, J. (2009) · Physical Review Letters · doi:10.1103/physrevlett.103.038101 · Cited by 77 · see citing works
Charcot–Marie–Tooth disease and intracellular traffic
Bucci, C., Bakke, O., & Progida, C. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.03.003 · Cited by 76 · see citing works
Endocytic Trafficking of Sphingomyelin Depends on Its Acyl Chain Length
Koivusalo, M., Jansen, M., Somerharju, P. J., & Ikonen, E. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-04-0330 · Cited by 76 · see citing works
The Vps27/Hse1 Complex Is a GAT Domain-Based Scaffold for Ubiquitin-Dependent Sorting
Prag, G., Watson, H. A., Kim, Y. C., Beach, B. M., Ghirlando, R., Hummer, G., Bonifacino, J. S., & Hurley, J. H. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.04.013 · Cited by 75 · see citing works
Liaison alcaline: Pals entice non-endosomal ESCRTs to the plasma membrane for pH signaling
Peñalva, M. A., Lucena‐Agell, D., & Arst, H. N. (2014) · Current Opinion in Microbiology · doi:10.1016/j.mib.2014.09.005 · Cited by 74 · see citing works
CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines
Belly, A., Bodon, G., Blot, B., Bouron, A., Sadoul, R., & Goldberg, Y. (2010) · Journal of Cell Science · doi:10.1242/jcs.068817 · Cited by 73 · see citing works
Endocytic routes to Notch activation
Baron, M. (2012) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2012.01.008 · Cited by 72 · see citing works
Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies
Eden, E. R., White, I. J., & Futter, C. E. (2009) · Biochemical Society Transactions · doi:10.1042/bst0370173 · Cited by 71 · see citing works
Tu, C., Ortega-Cava, C. F., Winograd, P., Stanton, M. J., Reddi, A. L., Dodge, I. L., Arya, R., Dimri, M., Clubb, R. J., Naramura, M., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1009471107 · Cited by 71 · see citing works
Galindo, A., Hervás-Aguilar, A., Rodríguez-Galán, O., Vincent, O., Arst, H., Tilburn, J., & Peñalva, M. (2007) · Traffic : the International Journal of Intracellular Transport · doi:10.1111/j.1600-0854.2007.00620.x · Cited by 79 · see citing works
Marschalek, R. (2015) · Annals of Laboratory Medicine · doi:10.3343/alm.2016.36.2.85 · Cited by 71 · see citing works
Irie, T., Shimazu, Y., Yoshida, T., & Sakaguchi, T. (2006) · Journal of Virology · doi:10.1128/jvi.02218-06 · Cited by 71 · see citing works
Hybrid Structural Model of the Complete Human ESCRT-0 Complex
Ren, X., Kloer, D. P., Kim, Y. C., Ghirlando, R., Saidi, L. F., Hummer, G., & Hurley, J. H. (2009) · Structure · doi:10.1016/j.str.2009.01.012 · Cited by 66 · see citing works
Welsch, S., Habermann, A., Jäger, S., Müller, B., Krijnse‐Locker, J., & Kräusslich, H. (2006) · Traffic · doi:10.1111/j.1600-0854.2006.00489.x · Cited by 65 · see citing works
ESCRT-III polymers in membrane neck constriction
Guizetti, J., & Gerlich, D. W. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.11.007 · Cited by 64 · see citing works
Kovalev, N., de Castro, I. F., Pogany, J., Barajas, D., Pathak, K. B., Risco, C., & Nagy, P. D. (2016) · Journal of Virology · doi:10.1128/jvi.02775-15 · Cited by 64 · see citing works
The ESCRT‐I Subunit TSG101 Controls Endosome‐to‐Cytosol Release of Viral RNA
Luyet, P., Falguières, T., Pons, V., Pattnaik, A. K., & Gruenberg, J. E. (2008) · Traffic · doi:10.1111/j.1600-0854.2008.00820.x · Cited by 63 · see citing works
Ubiquitinylation of Igβ Dictates the Endocytic Fate of the B Cell Antigen Receptor
Zhang, M., Veselits, M., O’Neill, S. K., Hou, P., Reddi, A. L., Berlin, I., Ikeda, M., Nash, P., Longnecker, R., Band, H., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.7.4435 · Cited by 62 · see citing works
Rodríguez‐Galán, O., Galindo, A., Hervás‐Aguilar, A., Arst, H. N., & Peñalva, M. A. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m808645200 · Cited by 62 · see citing works
Lutz, D., Wolters‐Eisfeld, G., Joshi, G., Djogo, N., Jakovčevski, I., Schachner, M., & KLEENE, R. B. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.346759 · Cited by 61 · see citing works
Vesicle formation by self-assembly of membrane-bound matrix proteins into a fluidlike budding domain
Shnyrova, A. V., Ayllón, J., Mikhalyov, I. I., Villar, E., Zimmerberg, J. J., & Frolov, V. A. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200705062 · Cited by 61 · see citing works
Ahmed, I., Akram, Z., Iqbal, H. M. N., & Munn, A. L. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.01.015 · Cited by 61 · see citing works
Roxrud, I., Stenmark, H., & Malerød, L. (2010) · Biology of the Cell · doi:10.1042/bc20090161 · Cited by 61 · see citing works
Self-citation
- Authors
- Slagsvold, T., Pattni, K., Malerød, L., & Stenmark, H.
- Affiliations
- University of Oslo (NO)
- Corresponding author
- Stenmark, Harald
- Venue
- Trends in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2006-06
- Volume
- 16
- Issue
- 6
- Pages
- 317-326
- ISSN
- 0962-8924 (ISSN-L)
- OpenAlex
- W2020212191
- Cited by
- 238
- References
- 92
- Citations by year
- 2026: 6 · 2025: 2 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 5 · 2020: 4 · 2019: 8 · 2018: 6 · 2017: 6 · 2016: 3 · 2015: 4 · 2014: 9 · 2013: 5 · 2012: 18
- FWCI
- 3.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ubiquitin and proteasome pathways
- Health Sciences › Medicine › Epidemiology › Autophagy in Disease and Therapy
- Keywords
- ESCRT proteins, multivesicular body biogenesis, ubiquitin-mediated proteolysis, membrane protein sorting, tumor suppression, viral budding
- MeSH terms
- Tsg101 Protein, Animals, DNA-Binding Proteins, Humans, Models, Biological, Protein Processing, Post-Translational, Endosomes, Transcription Factors, Virus Physiological Phenomena, Evolution, Molecular, Protein Transport, Transport Vesicles, Tumor Suppressor Proteins, Ubiquitin, Vesicular Transport Proteins, Multiprotein Complexes, Endosomal Sorting Complexes Required for Transport
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review