Skeletal muscle autophagy: a new metabolic regulator

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Kim, J., Kundu, M., Viollet, B., & Guan, K.-L. (2011) · Nature Cell Biology · doi:10.1038/ncb2152 · Cited by 7,227 · see citing works

Autophagy in the Pathogenesis of Disease

Levine, B., & Kroemer, G. (2008) · Cell · doi:10.1016/j.cell.2007.12.018 · Cited by 7,069 · see citing works

Autophagy fights disease through cellular self-digestion

Mizushima, N., Levine, B., Cuervo, A. M., & Klionsky, D. J. (2008) · Nature · doi:10.1038/nature06639 · Cited by 6,452 · see citing works

Autophagy regulates lipid metabolism

Singh, R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M., Tanaka, K., Cuervo, A. M., & Czaja, M. J. (2009) · Nature · doi:10.1038/nature07976 · Cited by 3,975 · see citing works

Fiber Types in Mammalian Skeletal Muscles

Schiaffino, S., & Reggiani, C. (2011) · Physiological Reviews · doi:10.1152/physrev.00031.2010 · Cited by 3,022 · see citing works

The Beclin 1 network regulates autophagy and apoptosis

Kang, R., Zeh, H. J., Lotze, M. T., & Tang, D. (2011) · Cell Death & Differentiation · doi:10.1038/cdd.2010.191 · Cited by 2,485 · see citing works

In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

Mizushima, N., Yamamoto, A., Matsui, M., Yoshimori, T., & Ohsumi, Y. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-09-0704 · Cited by 2,323 · see citing works

mTOR regulation of autophagy

Jung, C. H., Ro, S.-H., Cao, J., Otto, N. M., & Kim, D.-H. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.01.017 · Cited by 2,090 · see citing works

Autophagy and Metabolism

Rabinowitz, J. D., & White, E. (2010) · Science · doi:10.1126/science.1193497 · Cited by 1,982 · see citing works

FoxO3 Controls Autophagy in Skeletal Muscle In Vivo

Mammucari, C., Milan, G., Romanello, V., Masiero, E., Rudolf, R., Del Piccolo, P., Burden, S. J., Di Lisi, R., Sandri, C., Zhao, J., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.11.001 · Cited by 1,953 · see citing works

The pathways of mitophagy for quality control and clearance of mitochondria

Ashrafi, G., & Schwarz, T. L. (2013) · Cell Death & Differentiation · doi:10.1038/cdd.2012.81 · Cited by 1,900 · see citing works

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H ⁺ -ATPase

Zoncu, R., Bar-Peled, L., Efeyan, A., Wang, S., Sancak, Y., & Sabatini, D. M. (2011) · Science · doi:10.1126/science.1207056 · Cited by 1,673 · see citing works

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells.

Zhao, J., Brault, J. J., Schild, A., Cao, P., Sandri, M., Schiaffino, S., Lecker, S. H., & Goldberg, A. L. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.11.004 · Cited by 1,489 · see citing works

Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

Guertin, D. A., Stevens, D. M., Thoreen, C. C., Burds, A. A., Kalaany, N. Y., Moffat, J., Brown, M., Fitzgerald, K. J., & Sabatini, D. M. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.10.007 · Cited by 1,409 · see citing works

Autophagy is required to maintain muscle mass.

Masiero, E., Agatea, L., Mammucari, C., Blaauw, B., Loro, E., Komatsu, M., Metzger, D., Reggiani, C., Schiaffino, S., & Sandri, M. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.10.008 · Cited by 1,282 · see citing works

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

He, C., Bassik, M. C., Moresi, V., Sun, K., Wei, Y., Zou, Z., An, Z., Loh, J., Fisher, J., Sun, Q., et al. (2012) · Nature · doi:10.1038/nature10758 · Cited by 1,136 · see citing works

Regulation of Muscle Fiber Type and Running Endurance by PPARδ

Wang, Y.-X., Zhang, C.-L., Yu, R. T., Cho, H. K., Nelson, M. C., Bayuga-Ocampo, C. R., Ham, J., Kang, H., & Evans, R. M. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020294 · Cited by 1,089 · see citing works

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

Lei, K., & Davis, R. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0438011100 · Cited by 1,068 · see citing works

The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor

Greer, E. L., Oskoui, P. R., Banko, M. R., Maniar, J. M., Gygi, M. P., Gygi, S. P., & Brunet, A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705325200 · Cited by 820 · see citing works

The Atg8 and Atg12 ubiquitin‐like conjugation systems in macroautophagy

Geng, J., & Klionsky, D. J. (2008) · EMBO Reports · doi:10.1038/embor.2008.163 · Cited by 781 · see citing works

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

Kim, K. H., Jeong, Y. T., Oh, H., Kim, S. H., Cho, J. M., Kim, Y.-N., Kim, S. S., Kim, D. H., Hur, K. Y., Kim, H. K., et al. (2013) · Nature Medicine · doi:10.1038/nm.3014 · Cited by 774 · see citing works

Autophagy regulates adipose mass and differentiation in mice

Singh, R., Xiang, Y., Wang, Y., Baikati, K., Cuervo, A. M., Luu, Y. K., Tang, Y., Pessin, J. E., Schwartz, G. J., & Czaja, M. J. (2009) · Journal of Clinical Investigation · doi:10.1172/jci39228 · Cited by 748 · see citing works

Effects of Aging on Muscle Fibre Type and Size

Deschenes, M. R. (2004) · Sports Medicine · doi:10.2165/00007256-200434120-00002 · Cited by 671 · see citing works

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

Bentzinger, C. F., Romanino, K., Cloëtta, D., Lin, S., Mascarenhas, J. B., Oliveri, F., Xia, J., Casanova, E., Costa, C. F., Brink, M., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.10.002 · Cited by 640 · see citing works

Adipose-specific deletion of <i>autophagy-related gene 7</i> ( <i>atg7</i> ) in mice reveals a role in adipogenesis

Zhang, Y., Goldman, S., Baerga, R., Zhao, Y., Komatsu, M., & Jin, S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906048106 · Cited by 634 · see citing works

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals.

Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., LeBrasseur, N. K., Yan, Z., & Spiegelman, B. M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704817200 · Cited by 611 · see citing works

Mitochondrial fission and remodelling contributes to muscle atrophy

Romanello, V., Guadagnin, E., Gomes, L., Roder, I., Sandri, C., Petersen, Y., Milan, G., Masiero, E., Del Piccolo, P., Foretz, M., et al. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.60 · Cited by 596 · see citing works

Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration

Grumati, P., Coletto, L., Sabatelli, P., Cescon, M., Angelin, A., Bertaggia, E., Blaauw, B., Urciuolo, A., Tiepolo, T., Merlini, L., et al. (2010) · Nature Medicine · doi:10.1038/nm.2247 · Cited by 540 · see citing works

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

Vieira, O. V., Botelho, R. J., Rameh, L. E., Brachmann, S. M., Matsuo, T., Davidson, H. W., Schreiber, A. D., Backer, J., Cantley, L. C., & Grinstein, S. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200107069 · Cited by 530 · see citing works

A block of autophagy in lysosomal storage disorders

Settembre, C., Fraldi, A., Jahreiss, L., Spampanato, C., Venturi, C. B., Medina, D. L., de Pablo, R., Tacchetti, C., Rubinsztein, D. C., & Ballabio, A. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm289 · Cited by 500 · see citing works

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Woldt, E., Sebti, Y., Solt, L. A., Duhem, C., Lancel, S., Eeckhoute, J., Hesselink, M. K. C., Paquet, C., Delhaye, S., Shin, Y., et al. (2013) · Nature Medicine · doi:10.1038/nm.3213 · Cited by 454 · see citing works

Autophagy in skeletal muscle

Sandri, M. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.01.056 · Cited by 451 · see citing works

Altered lipid content inhibits autophagic vesicular fusion

Koga, H., Kaushik, S., & Cuervo, A. M. (2010) · The FASEB Journal · doi:10.1096/fj.09-144519 · Cited by 429 · see citing works

Mechanisms for fiber-type specificity of skeletal muscle atrophy

Wang, Y., & Pessin, J. E. (2013) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328360272d · Cited by 415 · see citing works

Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

Wohlgemuth, S. E., Seo, A. Y., Marzetti, E., Lees, H. A., & Leeuwenburgh, C. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2009.11.002 · Cited by 397 · see citing works

Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance

Kaushik, S., Rodriguez-Navarro, J. A., Arias, E., Kiffin, R., Sahu, S., Schwartz, G. J., Cuervo, A. M., & Singh, R. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.06.008 · Cited by 382 · see citing works

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

Risson, V., Mazelin, L., Roceri, M., Sanchez, H., Moncollin, V., Corneloup, C., Richard-Bulteau, H., Vignaud, A., Baas, D., Defour, A., et al. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200903131 · Cited by 381 · see citing works

Bcl-2:Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch.

Marquez, R. T., & Xu, L. (2012) · PubMed · Cited by 364 · see citing works

The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy

Foletta, V. C., White, L. J., Larsen, A., Léger, B., & Russell, A. P. (2011) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-010-0919-9 · Cited by 357 · see citing works

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

Sanchez, A. M. J., Csibi, A., Raibon, A., Cornille, K., Gay, S., Bernardi, H., & Candau, R. B. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23399 · Cited by 329 · see citing works

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

Castets, P., Lin, S., Rion, N., Di Fulvio, S., Romanino, K., Guridi, M., Frank, S., Tintignac, L. A., Sinnreich, M., & Rüegg, M. A. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.03.015 · Cited by 302 · see citing works

Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle

Mammucari, C., Schiaffino, S., & Sandri, M. (2008) · Autophagy · doi:10.4161/auto.5905 · Cited by 295 · see citing works

Control of autophagy initiation by phosphoinositide 3‐phosphatase jumpy

Vergne, I., Roberts, E., Elmaoued, R. A., Tosch, V., Delgado, M. A., Proikas‐Cezanne, T., Laporte, J., & Deretic, V. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.159 · Cited by 270 · see citing works

AMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm

Pauly, M., Daussin, F., Burelle, Y., Li, T., Godin, R., Fauconnier, J., Koechlin-Ramonatxo, C., Hugon, G., Lacampagne, A., Coisy-Quivy, M., et al. (2012) · The American Journal of Pathology · doi:10.1016/j.ajpath.2012.04.004 · Cited by 225 · cited 1× · see citing works

Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles

Masiero, E., & Sandri, M. (2010) · Autophagy · doi:10.4161/auto.6.2.11137 · Cited by 220 · see citing works

Bcl-2 Phosphorylation by p38 MAPK

Chiara, G. D., Marcocci, M. E., Torcia, M. G., Lucibello, M., Rosini, P., Bonini, P., Higashimoto, Y., Damonte, G., Armirotti, A., Amodei, S., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511052200 · Cited by 199 · see citing works

Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission

Sandonà, D., Desaphy, J., Camerino, G. M., Bianchini, E., Ciciliot, S., Danieli‐Betto, D., Dobrowolny, G., Furlan, S., Germinario, E., Goto, K., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033232 · Cited by 191 · see citing works

Altered Skeletal Muscle Phenotypes in Calcineurin Aα and Aβ Gene-Targeted Mice

Parsons, S. A., Wilkins, B. J., Bueno, O. F., & Molkentin, J. D. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.12.4331-4343.2003 · Cited by 155 · see citing works

Autophagy in health and disease. 3. Involvement of autophagy in muscle atrophy

Sandri, M. (2010) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00531.2009 · Cited by 152 · see citing works

Lysosomal myopathies: An excessive build-up in autophagosomes is too much to handle

Malicdan, M. C. V., Noguchi, S., Nonaka, I., Säftig, P., & Nishino, I. (2008) · Neuromuscular Disorders · doi:10.1016/j.nmd.2008.04.010 · Cited by 151 · see citing works

Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice

Moresi, V., Carrer, M., Grueter, C. E., Rifki, O. F., Shelton, J. M., Richardson, J. A., Bassel‐Duby, R., & Olson, E. N. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121159109 · Cited by 143 · see citing works

PGC-1α regulates a HIF2α-dependent switch in skeletal muscle fiber types

Rasbach, K. A., Gupta, R. K., Ruas, J. L., Wu, J., Naseri, E., Estall, J. L., & Spiegelman, B. M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016089107 · Cited by 142 · see citing works

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Nemazanyy, I., Blaauw, B., Paolini, C., Caillaud, C., Protasi, F., Mueller, A., Proikas‐Cezanne, T., Russell, R. C., Guan, K., Nishino, I., et al. (2013) · EMBO Molecular Medicine · doi:10.1002/emmm.201202057 · Cited by 126 · see citing works

Reactive oxygen species and redox-regulation of skeletal muscle adaptations to exercise

Jackson, M. J. (2005) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2005.1773 · Cited by 125 · see citing works

Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle

Chang, N. C., Nguyen, M., Bourdon, J., Risse, P., Martin, J. G., Danialou, G., Rizzuto, R., Petrof, B. J., & Shore, G. C. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds048 · Cited by 113 · see citing works

The role of autophagy in the pathogenesis of glycogen storage disease type II (GSDII)

Nascimbeni, A. C., Fanin, M., Masiero, E., Angelini, C. I., & Sandri, M. (2012) · Cell Death and Differentiation · doi:10.1038/cdd.2012.52 · Cited by 106 · see citing works

Juvenile spinal muscular atrophy: A new hexosaminidase deficiency phenotype

Johnson, W. G., Wigger, H. J., Karp, H. R., Glaubiger, L. M., & Rowland, L. P. (1982) · Annals of Neurology · doi:10.1002/ana.410110103 · Cited by 105 · see citing works

Myogenin regulates denervation-dependent muscle atrophy in mouse soleus muscle

Macpherson, P. C. D., Wang, X., & Goldman, D. J. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23136 · Cited by 104 · see citing works

Mouse skeletal muscle fiber-type-specific macroautophagy and muscle wasting are regulated by a Fyn/STAT3/Vps34 signaling pathway

Yamada, E., Bastie, C. C., Koga, H., Wang, Y., Cuervo, A. M., & Pessin, J. E. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.03.014 · Cited by 103 · see citing works

Autophagic response to strenuous exercise in mouse skeletal muscle fibers

Salminen, A., & Vihko, V. (1984) · Virchows Archiv B Cell Pathology Including Molecular Pathology · doi:10.1007/bf02889856 · Cited by 100 · see citing works

Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice

Fetalvero, K. M., Yu, Y., Goetschkes, M., Liang, G., Valdez, R. A., Gould, T., Triantafellow, E., Bergling, S., Loureiro, J., Eash, J., et al. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01075-12 · Cited by 96 · see citing works

Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy

Mitsuhashi, S., Hatakeyama, H., Karahashi, M., Koumura, T., Nonaka, I., Hayashi, Y. K., Noguchi, S., Sher, R. B., Nakagawa, Y., Manfredi, G., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr305 · Cited by 95 · see citing works

Fyn-Dependent Regulation of Energy Expenditure and Body Weight Is Mediated by Tyrosine Phosphorylation of LKB1

Yamada, E., Pessin, J. E., Kurland, I. J., Schwartz, G. J., & Bastie, C. C. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2009.12.010 · Cited by 94 · see citing works

Zebrafish MTMR14 is required for excitation–contraction coupling, developmental motor function and the regulation of autophagy

Dowling, J. J., Low, S. E., Busta, A. S., & Feldman, E. L. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq153 · Cited by 87 · see citing works

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin‐proteasome pathways

Al‐Qusairi, L., Prokic, I., Amoasii, L., Kretz, C., Messaddeq, N., Mandel, J., & Laporte, J. (2013) · The FASEB Journal · doi:10.1096/fj.12-220947 · Cited by 76 · see citing works

Autophagy in Lysosomal Myopathies

Malicdan, M., & Nishino, I. (2012) · Brain Pathology · doi:10.1111/j.1750-3639.2011.00543.x · Cited by 74 · see citing works

Fiber Type Conversion by PGC-1α Activates Lysosomal and Autophagosomal Biogenesis in Both Unaffected and Pompe Skeletal Muscle

Takikita, S., Schreiner, C., Baum, R., Xie, T., Ralston, E., Plotz, P. H., & Raben, N. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015239 · Cited by 60 · see citing works

Runx1 Is a Co-activator with FOXO3 to Mediate Transforming Growth Factor β (TGFβ)-induced Bim Transcription in Hepatic Cells

Wildey, G. M., & Howe, P. H. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.027201 · Cited by 54 · see citing works

The metabolic modulator trimetazidine triggers autophagy and counteracts stress‐induced atrophy in skeletal muscle myotubes

Ferraro, E., Giammarioli, A. M., Caldarola, S., Lista, P., Feraco, A., Tinari, A., Salvatore, A. M., Malorni, W., Berghella, L., & Rosano, G. M. C. (2013) · FEBS Journal · doi:10.1111/febs.12484 · Cited by 47 · see citing works

Trimetazidine potentiates the effects of exercise training in patients with ischemic cardiomyopathy referred for cardiac rehabilitation

Belardinelli, R., Lacalaprice, F., Faccenda, E., & Volpe, L. (2008) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e328304feec · Cited by 36 · see citing works

Juvenile spinal muscular atrophy--a new hexosaminidase deficiency phenotype.

Johnson, W. G., Wigger, H. J., Karp, H., Glaubiger, L. M., & Rowland, L. P. (1981) · PubMed · Cited by 15 · see citing works

Muscle involvement in cholesterol ester storage disease

Navarro, C., Fernández, J. M., Domı́nguez, C., Aznar, A. O., Sancho, S., & García, J. (1992) · Neurology · doi:10.1212/wnl.42.5.1120 · Cited by 4 · see citing works

A Narrative Review of Cancer-Related Fatigue (CRF) and Its Possible Pathogenesis

Yang, S., Chu, S., Gao, Y., Ai, Q., Liu, Y., Li, X., & Chen, N. (2019) · Cells · doi:10.3390/cells8070738 · Cited by 237 · see citing works

Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination

Liu, C.-C., Lin, Y., Chen, Y.-H., Chen, C., Pang, L.-Y., Chen, H.-A., Wu, P., Lin, M.-Y., Jiang, S., Tsai, T., et al. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.11.001 · Cited by 224 · see citing works

Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations

Chen, Q., Kirk, K., Shurubor, Y. I., Zhao, D., Arreguin, A. J., Shahi, I., Valsecchi, F., Primiano, G., Calder, E. L., Carelli, V., et al. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.03.002 · Cited by 210 · see citing works

Degeneration of Neuromuscular Junction in Age and Dystrophy

Rudolf, R., Khan, M. M., Labeit, S., & Deschenes, M. R. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00099 · Cited by 186 · see citing works

The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulation

Bilodeau, P., Coyne, E. S., & Wing, S. S. (2016) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00125.2016 · Cited by 180 · see citing works

Energy metabolism in cachexia

Rohm, M., Zeigerer, A., Machado, J., & Herzig, S. (2019) · EMBO Reports · doi:10.15252/embr.201847258 · Cited by 164 · see citing works

Molecular mechanism of sarcopenia and cachexia: recent research advances

Sakuma, K., Aoi, W., & Yamaguchi, A. (2017) · Pflügers Archiv: European Journal of Physiology · doi:10.1007/s00424-016-1933-3 · Cited by 144 · see citing works

Platelet-Rich Plasma Activates Proinflammatory Signaling Pathways and Induces Oxidative Stress in Tendon Fibroblasts

Hudgens, J. L., Sugg, K. B., Grekin, J. A., Gumucio, J. P., Bedi, A., & Mendias, C. L. (2016) · The American Journal of Sports Medicine · doi:10.1177/0363546516637176 · Cited by 141 · see citing works

Skeletal muscle-specific <i>Prmt1</i> deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis

Choi, S., Jeong, H.-J., Kim, H., Choi, D., Cho, S.-C., Seong, J. K., Koo, S.-H., & Kang, J.-S. (2019) · Autophagy · doi:10.1080/15548627.2019.1569931 · Cited by 132 · see citing works

Current understanding of sarcopenia: possible candidates modulating muscle mass

Sakuma, K., Aoi, W., & Yamaguchi, A. (2014) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-014-1527-x · Cited by 128 · see citing works

Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine

Wang, X., Hua, P., He, C., & Chen, M. (2022) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.03.020 · Cited by 129 · see citing works

The Role of Autophagy in Skeletal Muscle Diseases

Xia, Q., Huang, X., Huang, J., Zheng, Y., March, M., Li, J., & Wei, Y. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.638983 · Cited by 130 · see citing works

Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle

de Castro, G. S., Simoes, E., Lima, J. D. C. C., Ortiz‐Silva, M., Festuccia, W. T., Tokeshi, F., de Alcântara, P. S. M., Otoch, J. P., Coletti, D., & Seelaender, M. C. L. (2019) · Cancers · doi:10.3390/cancers11091264 · Cited by 119 · see citing works

The Effects of Calorie Restriction on Autophagy: Role on Aging Intervention

Chung, K. W., & Chung, H. Y. (2019) · Nutrients · doi:10.3390/nu11122923 · Cited by 121 · see citing works

The Essential Autophagy Gene ATG7 Modulates Organ Fibrosis via Regulation of Endothelial-to-Mesenchymal Transition

Singh, K. K., Lovren, F., Pan, Y., Quan, A., Ramadan, A., Matkar, P. N., Ehsan, M., Sandhu, P., Mantella, L. E., Gupta, N., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.604603 · Cited by 118 · see citing works

Copper (II) and/or arsenite-induced oxidative stress cascades apoptosis and autophagy in the skeletal muscles of chicken

Wang, Y., Zhao, H., Shao, Y., Liu, J., Li, J., Luo, L., & Xing, M. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.05.013 · Cited by 111 · see citing works

Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains

Di Rienzo, M., Antonioli, M., Fusco, C., Liu, Y., Mari, M., Orhon, I., Refolo, G., Germani, F., Corazzari, M., Romagnoli, A., et al. (2019) · Science Advances · doi:10.1126/sciadv.aau8857 · Cited by 107 · see citing works

Out of Control: The Role of the Ubiquitin Proteasome System in Skeletal Muscle during Inflammation

Haberecht-Müller, S., Krüger, E., & Fielitz, J. (2021) · Biomolecules · doi:10.3390/biom11091327 · Cited by 108 · see citing works

Regulation of Beclin 1 Protein Phosphorylation and Autophagy by Protein Phosphatase 2A (PP2A) and Death-associated Protein Kinase 3 (DAPK3)

Fujiwara, N., Usui, T., Ohama, T., & Sato, K. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.704908 · Cited by 99 · see citing works

Understanding of sarcopenia: from definition to therapeutic strategies

Kim, J. W., Kim, R., Choi, H., Lee, S., & Bae, G. (2021) · Archives of Pharmacal Research · doi:10.1007/s12272-021-01349-z · Cited by 101 · see citing works

Mitochondria: Inadvertent targets in chemotherapy-induced skeletal muscle toxicity and wasting?

Sorensen, J. C., Cheregi, B. D., Timpani, C. A., Nurgali, K., Hayes, A., & Rybalka, E. (2016) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-016-3045-3 · Cited by 95 · see citing works

Lysosomal Two-pore Channel Subtype 2 (TPC2) Regulates Skeletal Muscle Autophagic Signaling

Lin, P., Duann, P., Komazaki, S., Park, K. H., Li, H., Sun, M., Sermersheim, M., Gumpper, K., Parrington, J., Galione, A., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.608471 · Cited by 84 · see citing works

Role of AMPK in regulation of LC3 lipidation as a marker of autophagy in skeletal muscle

Fritzen, A. M., Frøsig, C., Jeppesen, J. F., Jensen, T. E., Lundsgaard, A., Serup, A. K., Schjerling, P., Proud, C. G., Richter, E. A., & Kiens, B. (2016) · Cellular Signalling · doi:10.1016/j.cellsig.2016.03.005 · Cited by 82 · see citing works

Disuse-associated loss of the protease Lonp1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength

Xu, Z., Fu, T., Guo, Q., Zhou, D., Sun, W., Zhou, Z., Chen, X., Zhang, J., Liu, L., Xiao, L., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28557-5 · Cited by 82 · see citing works

Daily heat stress treatment rescues denervation‐activated mitochondrial clearance and atrophy in skeletal muscle

Tamura, Y., Kitaoka, Y., Matsunaga, Y., Hoshino, D., & Hatta, H. (2015) · The Journal of Physiology · doi:10.1113/jp270093 · Cited by 81 · see citing works

Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes

Li, H., Liu, S., Yuan, H., Niu, Y., & Fu, L. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.03.023 · Cited by 77 · see citing works

Distribution of Dietary Protein Intake in Daily Meals Influences Skeletal Muscle Hypertrophy Via the Circadian Clock

Aoyama, S., Kim, H., Hirooka, R., Tanaka, M., Shimoda, T., Chijiki, H., Kojima, S., Sasaki, K., Takahashi, K., Makino, S., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2021.109336 · Cited by 73 · see citing works

β-Hydroxy-β-Methylbutyrate (HMB) Normalizes Dexamethasone-Induced Autophagy-Lysosomal Pathway in Skeletal Muscle

Girón, M. D., Vílchez, J. D., Shreeram, S., Salto, R., Manzano, M., Cabrera, E., Campos, N., Edens, N. K., Rueda, R., & López-Pedrosa, J. M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0117520 · Cited by 69 · see citing works

The Intriguing Regulators of Muscle Mass in Sarcopenia and Muscular Dystrophy

Sakuma, K., Aoi, W., & Yamaguchi, A. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00230 · Cited by 69 · see citing works

Skeletal Muscle Homeostasis in Duchenne Muscular Dystrophy: Modulating Autophagy as a Promising Therapeutic Strategy

Palma, C. D., Perrotta, C., Pellegrino, P., Clementi, E., & Cervia, D. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00188 · Cited by 66 · see citing works

Communication Between Autophagy and Insulin Action: At the Crux of Insulin Action-Insulin Resistance?

Frendo‐Cumbo, S., Tokarz, V. L., Bilan, P. J., Brumell, J. H., & Klip, A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.708431 · Cited by 63 · see citing works

Platinum-induced muscle wasting in cancer chemotherapy: Mechanisms and potential targets for therapeutic intervention

Moreira‐Pais, A., Ferreira, R. M., & da Costa, R. M. G. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.07.010 · Cited by 63 · see citing works

Dysregulated mitochondrial Ca2+ and ROS signaling in skeletal muscle of ALS mouse model

Zhou, J., Li, A., Li, X., & Yi, J. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.01.024 · Cited by 58 · see citing works

Crosstalk between autophagy and insulin resistance: evidence from different tissues

Sadeghi, A., Niknam, M., Momeni‐Moghaddam, M. A., Shabani, M., Aria, H., Bastin, A., Teimouri, M., Meshkani, R., & Akbari, H. (2023) · European journal of medical research · doi:10.1186/s40001-023-01424-9 · Cited by 65 · see citing works

Recent advances in pharmacological, hormonal, and nutritional intervention for sarcopenia

Sakuma, K., & Yamaguchi, A. (2017) · Pflügers Archiv: European Journal of Physiology · doi:10.1007/s00424-017-2077-9 · Cited by 34 · see citing works

Suppressed autophagy flux in skeletal muscle of an amyotrophic lateral sclerosis mouse model during disease progression

Xiao, Y., Ma, C., Yi, J., Wu, S., Guo, L., Xu, X., Lin, P., Sun, J., & Zhou, J. (2015) · Physiological Reports · doi:10.14814/phy2.12271 · Cited by 56 · see citing works

The role of TGF-β signaling in muscle atrophy, sarcopenia and cancer cachexia

Lan, X., Deng, C., Wang, Q., Zhao, L., Jiao, B., & Xiang, Y. (2024) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2024.114513 · Cited by 56 · see citing works

Autophagy in Alcohol-Induced Multiorgan Injury: Mechanisms and Potential Therapeutic Targets

Li, Y., Wang, S., Ni, H., Huang, H., & Ding, W. (2014) · BioMed Research International · doi:10.1155/2014/498491 · Cited by 54 · see citing works

Resistance Exercise, Aging, Disuse, and Muscle Protein Metabolism

McKendry, J., Stokes, T., Mcleod, J. C., & Phillips, S. M. (2021) · Comprehensive physiology · doi:10.1002/cphy.c200029 · Cited by 71 · see citing works

IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice

Valladares-Ide, D., Utreras‐Mendoza, Y., Campos, C., Morales, C., Díaz‐Vegas, A., Contreras‐Ferrat, A. E., Westermeier, F., Jaimovich, E., Marchi, S., Pinton, P., et al. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.08.042 · Cited by 51 · see citing works

The Role of Lonp1 on Mitochondrial Functions during Cardiovascular and Muscular Diseases

Zanini, G., Selleri, V., Malerba, M., Solodka, K., Sinigaglia, G., Nasi, M., Mattioli, A. V., & Pinti, M. (2023) · Antioxidants · doi:10.3390/antiox12030598 · Cited by 49 · see citing works

Regulation of the Tumor-Suppressor BECLIN 1 by Distinct Ubiquitination Cascades

Boutouja, F., Brinkmeier, R., Mastalski, T., Magraoui, F. E., & Platta, H. W. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18122541 · Cited by 49 · see citing works

The Importance of mTOR Trafficking for Human Skeletal Muscle Translational Control

Hodson, N. W., & Philp, A. (2018) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000173 · Cited by 50 · see citing works

Muscle dysfunction caused by loss ofMagel2in a mouse model of Prader-Willi and Schaaf-Yang syndromes

Kamaludin, A. A., Smolarchuk, C., Bischof, J. M., Eggert, R., Greer, J. J., Ren, J. T., Lee, J. J., Yokota, T., Berry, F. B., & Wevrick, R. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw225 · Cited by 45 · see citing works

Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy

Zhiyin, L., Jinliang, C., Qiunan, C., Yunfei, Y., & Xiao, Q. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111590 · Cited by 46 · see citing works

Muscle LIM protein/CSRP3: a mechanosensor with a role in autophagy

Rashid, M. M., Runci, A., Polletta, L., Carnevale, I., Morgante, E., Foglio, E., Arcangeli, T., Sansone, L., Russo, M. A., & Tafani, M. (2015) · Cell Death Discovery · doi:10.1038/cddiscovery.2015.14 · Cited by 44 · see citing works

Insulin‐Like Growth Factor I Regulation and Its Actions in Skeletal Muscle

Vassilakos, G., & Barton, E. R. (2018) · Comprehensive physiology · doi:10.1002/cphy.c180010 · Cited by 47 · see citing works

ALS-associated mutation SOD1G93A leads to abnormal mitochondrial dynamics in osteocytes

Wang, H., Yi, J., Li, X., Xiao, Y., Dhakal, K. R., & Zhou, J. (2017) · Bone · doi:10.1016/j.bone.2017.10.010 · Cited by 43 · see citing works

The muscle to bone axis (and viceversa): An encrypted language affecting tissues and organs and yet to be codified?

Bosco, F., Musolino, V., Gliozzi, M., Nucera, S., Carresi, C., Zito, M. C., Scarano, F., Scicchitano, M., Reale, F., Ruga, S., et al. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105427 · Cited by 45 · see citing works

Absence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation

Karam, C. N., Yi, J., Xiao, Y., Dhakal, K. R., Zhang, L., Li, X., Manno, C. D., Xu, J., Li, K., Cheng, H., et al. (2017) · Skeletal Muscle · doi:10.1186/s13395-017-0123-0 · Cited by 42 · see citing works

Cancer-Induced Reprogramming of Host Glucose Metabolism: “Vicious Cycle” Supporting Cancer Progression

Schwartsburd, P. M. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.00218 · Cited by 42 · see citing works

Effects of steroid treatment on growth, nutrient partitioning, and expression of genes related to growth and nutrient metabolism in adult triploid rainbow trout (Oncorhynchus mykiss)

Cleveland, B. M., & Weber, G. M. (2016) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2016.01.001 · Cited by 40 · see citing works

The emergence of protein arginine methyltransferases in skeletal muscle and metabolic disease

vanLieshout, T. L., & Ljubicic, V. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00251.2019 · Cited by 40 · see citing works

Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle

Sato, Y., Ohtsubo, H., Nihei, N., Kaneko, T., Sato, Y., Adachi, S.-I., Kondo, S., Nakamura, M., Mizunoya, W., Iida, H., et al. (2017) · The FASEB Journal · doi:10.1096/fj.201700493r · Cited by 38 · see citing works

Physiological and Pathological Mitochondrial Clearance Is Related to Pectoralis Major Muscle Pathogenesis in Broilers With Wooden Breast Syndrome

Hosotani, M., Kawasaki, T., Hasegawa, Y., Wakasa, Y., Hoshino, M., Takahashi, N., Ueda, H. H., Takaya, T., Iwasaki, T., & Watanabe, T. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00579 · Cited by 39 · see citing works

The Current Landscape of Pharmacotherapies for Sarcopenia

Bahat, G., & Özkök, S. (2024) · Drugs & Aging · doi:10.1007/s40266-023-01093-7 · Cited by 39 · see citing works

Regulation of protein degradation pathways by amino acids and insulin in skeletal muscle of neonatal pigs

Suryawan, A., & Davis, T. A. (2014) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/2049-1891-5-8 · Cited by 38 · see citing works

The Autophagy Regulatory Molecule CSRP3 Interacts with LC3 and Protects Against Muscular Dystrophy

Cui, C., Han, S., Tang, S., He, H., Shen, X., Zhao, J., Chen, Y., Wei, Y., Wang, Y., Zhu, Q. C., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030749 · Cited by 37 · see citing works

How autophagy can restore proteostasis defects in multiple diseases?

Joshi, V., Upadhyay, A., Prajapati, V. K., & Mishra, A. (2020) · Medicinal Research Reviews · doi:10.1002/med.21662 · Cited by 38 · see citing works

Pharmacological inhibition of myostatin protects against skeletal muscle atrophy and weakness after anterior cruciate ligament tear

Wolfe, C. N., Gumucio, J. P., Grekin, J. A., Khouri, R. K., Russell, A. J., Bedi, A., & Mendias, C. L. (2017) · Journal of Orthopaedic Research® · doi:10.1002/jor.23537 · Cited by 36 · see citing works

Mechanical Signaling in the Pathophysiology of Critical Illness Myopathy

Corpeño, R., & Larsson, L. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00023 · Cited by 36 · see citing works

Endothelial Senescence and Chronic Fatigue Syndrome, a COVID-19 Based Hypothesis

Sfera, A., Osorio, C., del Campo, C. M. Z. M., Pereida, S., Maurer, S., Maldonado, J. C., & Kozlakidis, Z. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.673217 · Cited by 30 · see citing works

Exercise Reduces the Resumption of Tumor Growth and Proteolytic Pathways in the Skeletal Muscle of Mice Following Chemotherapy

de Lima, E. A., Teixeira, A. A. D. S., Biondo, L. A., Diniz, T. A., Silveira, L. S., Coletti, D., Busquets, S., & Neto, J. C. R. (2020) · Cancers · doi:10.3390/cancers12113466 · Cited by 31 · see citing works

Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle

Rivera, J. C. A., Ábrigo, J., Tacchi, F., Simón, F., Brandan, E., Santos, R. A. S., Bäder, M., Chiong, M., & Cabello‐Verrugio, C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249344 · Cited by 31 · see citing works

The impact of postexercise essential amino acid ingestion on the ubiquitin proteasome and autophagosomal-lysosomal systems in skeletal muscle of older men

Dickinson, J. M., Reidy, P. T., Gundermann, D. M., Borack, M. S., Walker, D. K., D’Lugos, A. C., Volpi, E., & Rasmussen, B. B. (2016) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00632.2016 · Cited by 30 · see citing works

Fasting Drives Nrf2-Related Antioxidant Response in Skeletal Muscle

Lettieri‐Barbato, D., Minopoli, G., Caggiano, R., Izzo, R., Santillo, M., Aquilano, K., & Faraonio, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207780 · Cited by 28 · see citing works

Phosphate stimulates myotube atrophy through autophagy activation: evidence of hyperphosphatemia contributing to skeletal muscle wasting in chronic kidney disease

Zhang, Y., Yang, M. G., Bao, J., Gu, L., Yu, H., & Yuan, W. (2018) · BMC Nephrology · doi:10.1186/s12882-018-0836-2 · Cited by 30 · see citing works

Filamin C regulates skeletal muscle atrophy by stabilizing dishevelled-2 to inhibit autophagy and mitophagy

Han, S., Cui, C., Zhao, X., Zhang, Y., Zhang, Y. L., Zhao, J., Shen, X., He, H., Wang, J., Ma, M., et al. (2021) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2021.11.022 · Cited by 29 · see citing works

Widespread modulation of gene expression by copy number variation in skeletal muscle

Geistlinger, L., da Silva, V. H., César, A. S. M., Tizioto, P. C., Waldron, L., Zimmer, R., Regitano, L. C. D. A., & Coutinho, L. L. (2018) · Scientific Reports · doi:10.1038/s41598-018-19782-4 · Cited by 29 · see citing works

Perturbation of PI3K/Akt signaling affected autophagy modulation in dystrophin-deficient myoblasts

Yazid, M. D., & Chen, H.-C. (2021) · Cell Communication and Signaling · doi:10.1186/s12964-021-00785-0 · Cited by 27 · see citing works

Resistance Exercise, Aging, Disuse, and Muscle Protein Metabolism

McKendry, J., Stokes, T., Mcleod, J. C., & Phillips, S. M. (2021) · Comprehensive physiology · doi:10.1002/j.2040-4603.2021.tb00179.x · Cited by 28 · see citing works

A Collagen Hydrolysate Containing Tripeptides Ameliorates Sarcopenia in Middle-Aged Mice

Kim, J. E., Kwon, E., & Han, Y. (2022) · Molecules · doi:10.3390/molecules27092718 · Cited by 26 · see citing works

An integrative correlation of myopathology, phenotype and genotype in late onset Pompe disease

Kulessa, M., Weyer-Menkhoff, I., Viergutz, L., Kornblum, C., Claeys, K. G., Schneider, I., Plöckinger, U., Young, P., Boentert, M., Vielhaber, S., et al. (2019) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12580 · Cited by 25 · see citing works

Effects of crowding on the three main proteolytic mechanisms of skeletal muscle in rainbow trout (Oncorhynchus mykiss)

Valenzuela, C., Ponce, C., Zuloaga, R., González, P., Avendaño-Herrera, R. E., Valdés, J. A., & Molina, A. (2020) · BMC Veterinary Research · doi:10.1186/s12917-020-02518-w · Cited by 25 · see citing works

Fighting obesity: When muscle meets fat

Yang, X., Bi, P., & Kuang, S. (2014) · Adipocyte · doi:10.4161/21623945.2014.964075 · Cited by 25 · see citing works

Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells

Park, S., Choi, Y., Jung, N., Kim, J., Oh, S., Yu, Y., Ahn, J., Jo, I., Choi, B., & Jung, S. (2017) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2017.2898 · Cited by 25 · see citing works

New Molecular Targets and Lifestyle Interventions to Delay Aging Sarcopenia

Sanchis-Gomar, F., Pareja-Galeano, H., Mayero, S., Perez-Quilis, C., & Lucia, A. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00156 · Cited by 24 · see citing works

Unacylated ghrelin restores insulin and autophagic signaling in skeletal muscle of diabetic mice

Tam, B. T., Pei, X. M., Yung, B. Y., Yip, S. P., Chan, L., Wong, S. C. C., & Siu, P. M. (2015) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-015-1721-5 · Cited by 24 · see citing works

Age, gender and side-stratified grip strength norms and related socio-demographic factors for 20–80 years Iranian healthy population: Comparison with consolidated and international norms

Rostamzadeh, S., Saremi, M., & Bradtmiller, B. (2020) · International Journal of Industrial Ergonomics · doi:10.1016/j.ergon.2020.103003 · Cited by 22 · see citing works

Longitudinal assessment of metal concentrations and copper isotope ratios in the G93A SOD1 mouse model of amyotrophic lateral sclerosis

Enge, T. G., Ecroyd, H. W., Jolley, D. F., Yerbury, J. J., & Dosseto, A. (2016) · Metallomics · doi:10.1039/c6mt00270f · Cited by 21 · see citing works

Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle

Tamura, Y., Matsunaga, Y., Kitaoka, Y., & Hatta, H. (2016) · The Journals of Gerontology Series A · doi:10.1093/gerona/glw063 · Cited by 21 · see citing works

Acute Heat Exposure Alters Autophagy Signaling in C2C12 Myotubes

Summers, C. M., & Valentine, R. J. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2019.01521 · Cited by 19 · see citing works

Dysregulated Autophagy and Mitophagy in a Mouse Model of Duchenne Muscular Dystrophy Remain Unchanged Following Heme Oxygenase-1 Knockout

Mucha, O., Kaziród, K., Podkalicka, P., Rusin, K., Dulak, J., & Łoboda, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010470 · Cited by 20 · see citing works

Lactate-induced autophagy activation: unraveling the therapeutic impact of high-intensity interval training on insulin resistance in type 2 diabetic rats

Pirani, H., Soltany, A., Rezaei, M. H., Fard, A. K., Nikooie, R., Khoramipoor, K., Chamari, K., & Khoramipour, K. (2024) · Scientific Reports · doi:10.1038/s41598-023-50589-0 · Cited by 20 · see citing works

Advance in topical biomaterials and mechanisms for the intervention of pressure injury

Pan, Y., Yang, D., Zhou, M., Liu, Y., Pan, J., Wu, Y., Huang, L., & Li, H. (2023) · iScience · doi:10.1016/j.isci.2023.106956 · Cited by 19 · see citing works

Poor Bone Quality in Patients With Amyotrophic Lateral Sclerosis

Caplliure‐Llopis, J., Escrivá, D., Benlloch, M., Ortí, J. E. D. L. R., Estrela, J. M., & Barrios, C. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.599216 · Cited by 18 · see citing works

The melanocortin receptor type 3 agonist d -Trp(8)-γMSH decreases inflammation and muscle wasting in arthritic rats

Gómez-SanMiguel, A. B., Martı́n, A. I., Nieto‐Bona, M. P., Fernández‐Galaz, C., Villanúa, M. Á., & López‐Calderón, A. (2015) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12036 · Cited by 18 · see citing works

Differences in the expression of genes involved in skeletal muscle proteolysis between broiler and layer chicks during food deprivation

Saneyasu, T., Kimura, S., Inui, M., Yoshimoto, Y., Honda, K., & Kamisoyama, H. (2015) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2015.04.007 · Cited by 18 · see citing works

Protein homeostasis in LGMDR9 (LGMD2I) – The role of ubiquitin–proteasome and autophagy–lysosomal system

Franekova, V., Storjord, H. I., Leivseth, G., & Nilssen, Ø. (2020) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12684 · Cited by 17 · see citing works

How Do Skeletal Muscles Die? An Overview

Carmeli, E., Aizenbud, D., & Rom, O. (2015) · Advances in experimental medicine and biology · doi:10.1007/5584_2015_140 · Cited by 17 · see citing works

Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice

Miyake, M., Kuroda, M., Kiyonari, H., Takehana, K., Hisanaga, S., Morimoto, M., Zhang, J., Oyadomari, M., Sakaue, H., & Oyadomari, S. (2017) · PLoS ONE · doi:10.1371/journal.pone.0179955 · Cited by 16 · see citing works

Cancer-associated muscle weakness - From triggers to molecular mechanisms

Shorter, E., Engman, V., & Lanner, J. T. (2024) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2024.101260 · Cited by 16 · see citing works

Activation of macroautophagy and chaperone-mediated autophagy in human skeletal muscle by high-intensity exercise in normoxia and hypoxia and after recovery with or without post-exercise ischemia

Martinez‐Canton, M., Galván-Álvarez, V., Gallego-Selles, Á., Gelabert‐Rebato, M., García-Gonzalez, E., González, J. J., Martín-Rincón, M., & Calbet, J. A. L. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.07.012 · Cited by 16 · see citing works

Plectin regulates Wnt signaling mediated-skeletal muscle development by interacting with Dishevelled-2 and antagonizing autophagy

Yin, H., Han, S., Cui, C., Wang, Y., Li, D., & Zhu, Q. (2021) · Gene · doi:10.1016/j.gene.2021.145562 · Cited by 16 · see citing works

O-GlcNAcylation: The Underestimated Emerging Regulators of Skeletal Muscle Physiology

Liu, Y., Hu, Y., Fan, W.-X., Quan, X., Xu, B., & Li, S. (2022) · Cells · doi:10.3390/cells11111789 · Cited by 15 · see citing works

A muscle-centric view of time-restricted feeding for older adults

Lees, M., Hodson, N., & Moore, D. (2021) · Current opinion in clinical nutrition and metabolic care · doi:10.1097/mco.0000000000000789 · Cited by 16 · see citing works

Sarcopenia; functional concerns, molecular mechanisms involved, and seafood as a nutritional intervention – review article

Jayawardena, T. U., Kim, S., & Jeon, Y. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1969889 · Cited by 15 · see citing works

Muscle-Bone Crosstalk in Amyotrophic Lateral Sclerosis

Zhou, J., Yi, J., & Bonewald, L. F. (2015) · Current Osteoporosis Reports · doi:10.1007/s11914-015-0281-0 · Cited by 14 · see citing works

Temporal analysis of skeletal muscle remodeling post hindlimb ischemia reveals intricate autophagy regulation

Scalabrin, M., Engman, V., MacCannell, A. D. V., Critchlow, A. J., Roberts, L. D., Yuldasheva, N. Y., & Bowen, T. S. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00174.2022 · Cited by 12 · see citing works

Kinetic modeling of leucine-mediated signaling and protein metabolism in human skeletal muscle

McColl, T. J., & Clarke, D. C. (2023) · iScience · doi:10.1016/j.isci.2023.108634 · Cited by 11 · see citing works

Self-Eating for Muscle Fitness: Autophagy in the Control of Energy Metabolism

Sebastián, D., & Antonio Zorzano, A. (2020) · Developmental Cell · doi:10.1016/j.devcel.2020.06.030 · Cited by 42 · see citing works

Fine-Tuning Autophagy in Skeletal Muscle: From Homeostasis to Muscle Wasting Disorders

Gou, Q., Ong, S. C., Lee, W. X., Krishnan, P. D. G., & Tang, H.-W. (2026) · Aging and Disease · doi:10.14336/ad.2026.0170 · Cited by 1 · see citing works

Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease

Vainshtein, A., Grumati, P., Sandri, M., & Bonaldo, P. (2014) · Journal of Molecular Medicine · doi:10.1007/s00109-013-1096-z · Cited by 88 · see citing works

The Role of Autophagy in Skeletal Muscle Diseases

Xia, Q., Huang, X., Huang, J., Zheng, Y., March, M., Li, J., & Wei, Y. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.638983 · Cited by 130 · see citing works

Autophagy in Skeletal Muscle Homeostasis and in Muscular Dystrophies

Grumati, P., & Bonaldo, P. (2012) · Cells · doi:10.3390/cells1030325 · Cited by 87 · see citing works