Cited by 499Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorDecision-Making and Behavioral Economics

The DOI matches its Crossref record; 93 of the 95 references it cites were found in a registry or an index.

Orbitofrontal cortex, decision-making and drug addiction

Open access

Schoenbaum, Geoffrey, Roesch, Matthew R., Stalnaker, Thomas A.·2006·Trends in Neurosciences

DOI 10.1016/j.tins.2005.12.006PMC PMC2430629

Open this paper in CoChat — free account

Abstract

The orbitofrontal cortex, as a part of prefrontal cortex, is implicated in executive function. However, within this broad region, the orbitofrontal cortex is distinguished by its unique pattern of connections with crucial subcortical associative learning nodes, such as basolateral amygdala and nucleus accumbens. By virtue of these connections, the orbitofrontal cortex is uniquely positioned to use associative information to project into the future, and to use the value of perceived or expected outcomes to guide decisions. This review will discuss recent evidence that supports this proposal and will examine evidence that loss of this signal, as the result of drug-induced changes in these brain circuits, might account for the maladaptive decision-making that characterizes drug addiction.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.tins.2005.12.006

Cites

93 of 93 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Untitled work
(1996) · Cited by 3,692
The Organization of Networks within the Orbital and Medial Prefrontal Cortex of Rats, Monkeys and Humans
Ongur, D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.206 · Cited by 2,627
The prefrontal cortex
Fuster, J. M. (1997) · Cited by 2,095
Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making
Bechara, A., Damasio, H., Damasio, A. R., & Lee, G. P. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-13-05473.1999 · Cited by 2,001
Circuitry of Primate Prefrontal Cortex and Regulation of Behavior by Representational Memory
Goldman‐Rakic, P. S. (1987) · Comprehensive Physiology · doi:10.1002/cphy.cp010509 · Cited by 1,960
Preliminary analysis of functions of the temporal lobes in monkeys
KLÜVER, H. (1939) · Archives of Neurology And Psychiatry · doi:10.1001/archneurpsyc.1939.02270240017001 · Cited by 1,696
The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.
Aggleton, J. P. (1992) · Wiley-Liss eBooks · Cited by 1,536
Dissociation in prefrontal cortex of affective and attentional shifts
Dias, R., Robbins, T. W., & Roberts, A. C. (1996) · Nature · doi:10.1038/380069a0 · Cited by 1,527
Relative reward preference in primate orbitofrontal cortex
Tremblay, L., & Schultz, W. (1999) · Nature · doi:10.1038/19525 · Cited by 1,314

Show all 95 references

Sorted by citations

Items 101–200 of 498

Chronic cocaine self-administration in rhesus monkeys: impact on associative learning, cognitive control, and working memory
Porter, J. N., Olsen, A. S., Gurnsey, K., Dugan, B. P., Jedema, H. P., & Bradberry, C. W. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5426-10.2011 · Cited by 97
Neural Basis of Emotional Decision Making in Trait Anxiety
Xu, P., Gu, R., Broster, L. S., Wu, R., Dam, N. T. V., Jiang, Y., Fan, J., & Luo, Y. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.1253-13.2013 · Cited by 96
The 5-HT2A serotonin receptor in executive function: Implications for neuropsychiatric and neurodegenerative diseases
Aznar, S., & Hervig, M. E.-S. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.02.008 · Cited by 99
Methamphetamine use and cognitive function: A systematic review of neuroimaging research
Sabrini, S., Wang, G., Lin, J. C., Kirk, I. J., & Curley, L. E. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.08.041 · Cited by 95
c‐Fos expression associated with reinstatement of cocaine‐seeking behavior by response‐contingent conditioned cues
Kufahl, P. R., Zavala, A. R., Singh, A., Thiel, K. J., Dickey, E. D., Joyce, J. N., & Neisewander, J. L. (2009) · Synapse · doi:10.1002/syn.20666 · Cited by 96
Evidences from Rewarding System, FRN and P300 Effect in Internet-Addiction in Young People
Balconi, M., Venturella, I., & Finocchiaro, R. (2017) · Brain Sciences · doi:10.3390/brainsci7070081 · Cited by 96
Memory and decision making
Redish, A. D., & Mizumori, S. J. Y. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.08.014 · Cited by 102
Decision-making and the frontal lobes
Volz, K. G., Schubotz, R. I., & von Cramon, D. Y. (2006) · Current Opinion in Neurology · doi:10.1097/01.wco.0000236621.83872.71 · Cited by 96
Habitual alcohol seeking: Modeling the transition from casual drinking to addiction
Barker, J. M., & Taylor, J. R. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.08.012 · Cited by 89
Orbitofrontal cortex lesions disrupt risk assessment in a novel serial decision-making task for rats
Pais-Vieira, M., Lima, D., & Galhardo, V. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.11.058 · Cited by 98
Increased Impulsivity during Withdrawal from Cocaine Self-Administration: Role for FosB in the Orbitofrontal Cortex
Winstanley, C. A., Bachtell, R. K., Theobald, D. E. H., Laali, S., Green, T. A., Kumar, A., Chakravarty, S., Self, D. W., & Nestler, E. J. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn094 · Cited by 92
Developmental Trajectories of the Orbitofrontal Cortex and Anhedonia in Middle Childhood and Risk for Substance Use in Adolescence in a Longitudinal Sample of Depressed and Healthy Preschoolers
Luby, J. L., Arpana Agrawal, A., Belden, A. C., Whalen, D. J., Tillman, R., & Barch, D. M. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.17070777 · Cited by 86
The associative basis of cue-elicited drug taking in humans
Hogarth, L., Dickinson, A., & Duka, T. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1735-9 · Cited by 89
Effects of subchronic phencyclidine (PCP) treatment on social behaviors and operant discrimination and reversal learning in C57BL/6J mice
Brigman, J. L. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.002.2009 · Cited by 85
Alterations in Brain Structure and Functional Connectivity in Alcohol Dependent Patients and Possible Association with Impulsivity
Wang, J., Fan, Y., Dong, Y., Ma, M., Ma, Y., Dong, Y., Niu, Y., Jiang, Y., Wang, H., Wang, Z., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0161956 · Cited by 83
Obesity, orbitofrontal structure and function are associated with food choice: a cross-sectional study
Cohen, J. I., Yates, K. F., Duong, M. T., & Convit, A. J. (2011) · BMJ Open · doi:10.1136/bmjopen-2011-000175 · Cited by 83
Efficient reinforcement learning: computational theories, neuroscience and robotics
Kawato, M., & Samejima, K. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.03.004 · Cited by 82
A neurobehavioral approach to addiction: implications for the opioid epidemic and the psychology of addiction
Bechara, A., Berridge, K. C., Bickel, W. K., Morón, J. A., Williams, S. B., & Stein, J. S. (2019) · Psychological Science in the Public Interest · doi:10.1177/1529100619860513 · Cited by 82
Dual neurocircuitry dysfunctions in disruptive behavior disorders: emotional responding and response inhibition
Hwang, S., Nolan, Z. T., White, S. F., Williams, W. C., Sinclair, S., & Blair, J. (2016) · Psychological Medicine · doi:10.1017/s0033291716000118 · Cited by 86
Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction
Olive, M. F. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.01.029 · Cited by 80
Gene expression profiling of post-mortem orbitofrontal cortex in violent suicide victims
Thalmeier, A., Dickmann, M., Giegling, I., Schneider, B., Hartmann, A. M., Maurer, K., Schnabel, A., Kauert, G. F., Möller, H., & Rujescu, D. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707007894 · Cited by 81
Neural Substrates and Circuits of Drug AddictionPreprint
Feltenstein, M. W., See, R. E., & Fuchs, R. A. (2020) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a039628 · Cited by 92
The Hedonic Brain: A Functional Neuroanatomy of Human Pleasure
Kringelbach, M. L. (2009) · Oxford University Press eBooks · doi:10.1093/oso/9780195331028.003.0014 · Cited by 80
Childhood Trauma Affects Stress-Related Interoceptive Accuracy
Schaan, V. K., Schulz, A., Rubel, J. A., Bernstein, M., Domes, G., Schächinger, H., & Vögele, C. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00750 · Cited by 79
Advances in understanding ventromedial prefrontal function
Fellows, L. K. (2007) · Neurology · doi:10.1212/01.wnl.0000257835.46290.57 · Cited by 80
Grounding the cognitive neuroscience of semantics in linguistic theory
Liina Pylkkänen, A., Brennan, J., & Bemis, D. K. (2010) · Language and Cognitive Processes · doi:10.1080/01690965.2010.527490 · Cited by 80
Decreased Prefrontal Lobe Interhemispheric Functional Connectivity in Adolescents with Internet Gaming Disorder: A Primary Study Using Resting-State fMRI
Wang, Y., Yin, Y., Sun, Y., Zhou, Y., Xue, C., Ding, W., Wang, W., Li, W., Xu, J., & Du, Y. (2015) · PLoS ONE · doi:10.1371/journal.pone.0118733 · Cited by 79
The left dorsolateral prefrontal cortex and caudate pathway: New evidence for cue-induced craving of smokers
Yuan, K., Yu, D., Bi, Y., Wang, R., Li, M., Zhang, Y., Dong, M., Zhai, J., Li, Y., Lu, X., et al. (2017) · Human Brain Mapping · doi:10.1002/hbm.23690 · Cited by 76
Functional role for cortical-striatal circuitry in modulating alcohol self-administration
Jaramillo, A. A., Randall, P. A., Stewart, S., Fortino, B., Voorhies, K. V., & Besheer, J. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.11.035 · Cited by 76
Neurobiological findings related to I nternet use disorders
Park, B., Han, D. H., & Roh, S. (2016) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12422 · Cited by 74
Internet addiction: Neuroimaging findings
Yuan, K., Qin, W., Liu, Y., & Tian, J. (2011) · Communicative & Integrative Biology · doi:10.4161/cib.17871 · Cited by 83
Brain responses to drug cues predict craving changes in abstinent heroin users: A preliminary study
Liu, S., Wang, S., Zhang, M., Xu, Y., Shao, Z., Chen, L., Yang, W., Liu, J., & Yuan, K. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118169 · Cited by 69
Reduced Neural Tracking of Prediction Error in Substance-Dependent Individuals
Tanabe, J., Reynolds, J. R., Krmpotich, T. D., Claus, E. D., Thompson, L. L., Du, Y. P., & Banich, M. T. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12091257 · Cited by 71
Medial prefrontal gray matter volume reductions in users of amphetamine-type stimulants revealed by combined tract-based spatial statistics and voxel-based morphometry
Daumann, J., Koester, P., Becker, B., Wagner, D. R., Imperati, D., Gouzoulis‐Mayfrank, E., & Tittgemeyer, M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.08.065 · Cited by 71
Current hypotheses on the mechanisms of alcoholism
Vetreno, R. P., & Crews, F. T. (2014) · Handbook of clinical neurology · doi:10.1016/b978-0-444-62619-6.00027-6 · Cited by 74
Addiction as vulnerabilities in the decision process
Redish, A. D., Jensen, S., & Johnson, A. C. (2008) · Behavioral and Brain Sciences · doi:10.1017/s0140525x08004986 · Cited by 69
Dopamine Development in the Mouse Orbital Prefrontal Cortex Is Protracted and Sensitive to Amphetamine in Adolescence
Hoops, D., Reynolds, L. M., Restrepo-Lozano, J. M., & Flores, C. (2018) · eNeuro · doi:10.1523/eneuro.0372-17.2017 · Cited by 70
Silencing the insular-striatal circuit decreases alcohol self-administration and increases sensitivity to alcohol
Jaramillo, A. A., Voorhies, K. V., Randall, P. A., & Besheer, J. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.04.007 · Cited by 68
The interaction between cognition and emotion
Liu, Y., Fu, Q., & Fu, X. (2009) · Chinese Science Bulletin · doi:10.1007/s11434-009-0632-2 · Cited by 70
A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children
Gerin, M. I., Puetz, V. B., Blair, J., White, S. F., Sethi, A., Hoffmann, F., Palmer, A. L., Viding, E. M., & McCrory, E. J. P. (2017) · Development and Psychopathology · doi:10.1017/s095457941700133x · Cited by 76
Lateral orbitofrontal gray matter abnormalities in subjects with problematic smartphone use
Lee, D., Namkoong, K., Lee, J., Lee, B. O., & Jung, Y.-C. (2019) · Journal of Behavioral Addictions · doi:10.1556/2006.8.2019.50 · Cited by 64
The Cambridge Handbook of Substance and Behavioral Addictions
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591 · Cited by 64
Computational theory-driven studies of reinforcement learning and decision-making in addiction: what have we learned?
Gueguen, M. C. M., Schweitzer, E. M., & Konova, A. B. (2020) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2020.08.007 · Cited by 67
A microdialysis study of the medial prefrontal cortex of adolescent and adult rats
Staiti, A. M., Morgane, P. J., Galler, J. R., Grivetti, J. Y., Bass, D. C., & Mokler, D. J. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.04.005 · Cited by 62
A further evaluation of decision-making under risk and under ambiguity in schizophrenia
Fond, G. B., Bayard, S., Capdevielle, D., Del-Monte, J., Mimoun, N., Macgregor, A., Boulenger, J., Gély-Nargeot, M.-C., & Raffard, S. (2012) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-012-0330-y · Cited by 68
Neural evidence for moral intuition and the temporal dynamics of interactions between emotional processes and moral cognition
Gui, D.-Y., Gan, T., & Liu, C. (2015) · Social Neuroscience · doi:10.1080/17470919.2015.1081401 · Cited by 60
Risk‐preference differentiates orbitofrontal cortex responses to freely chosen reward outcomes
Roitman, J. D., & Roitman, M. F. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07169.x · Cited by 57
Impact of Environmental Enrichment on Perineuronal Nets in the Prefrontal Cortex following Early and Late Abstinence from Sucrose Self-Administration in Rats
Slaker, M. L., Barnes, J., Sorg, B. A., & Grimm, J. W. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168256 · Cited by 57
A State Representation for Reinforcement Learning and Decision-Making in the Orbitofrontal Cortex
Schuck, N. W., Wilson, R., & Niv, Y. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812098-9.00012-7 · Cited by 66
Motivational Processes Underlying Substance Abuse Disorder
Meyer, P., King, C. P., & Ferrario, C. R. (2015) · Current topics in behavioral neurosciences · doi:10.1007/7854_2015_391 · Cited by 59
Substance use disorder and trauma.
Najavits, L. M., Hyman, S. M., Ruglass, L. M., Hien, D. A., & Read, J. P. (2017) · American Psychological Association eBooks · doi:10.1037/0000019-012 · Cited by 55
Neurophysiology of Reward-Guided Behavior: Correlates Related to Predictions, Value, Motivation, Errors, Attention, and Action
Bissonette, G. B., & Roesch, M. R. (2015) · Current topics in behavioral neurosciences · doi:10.1007/7854_2015_382 · Cited by 68
Smoking withdrawal is associated with increases in brain activation during decision making and reward anticipation: a preliminary study
Addicott, M. A., Baranger, D. A. A., Kozink, R. V., Smoski, M. J., Dichter, G. S., & McClernon, F. J. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2404-3 · Cited by 55
Orbitofrontal Cortex and Cognitive‐Motivational Impairments in Psychostimulant Addiction
Olausson, P., Jentsch, J. D., Krueger‐Burg, D., Tronson, N. C., Nairn, A. C., & Taylor, J. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1401.016 · Cited by 56
Molecular and Functional Imaging of Internet Addiction
Zhu, Y., Zhang, H., & Tian, M. (2015) · BioMed Research International · doi:10.1155/2015/378675 · Cited by 60
Association of basal forebrain volumes and cognition in normal aging
Wolf, D. G. F., Grothe, M. J., Fischer, F. U., Heinsen, H., Kilimann, I., Teipel, S. J., & Fellgiebel, A. (2013) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2013.11.002 · Cited by 53
Shared Neural Correlates Underlying Addictive Disorders and Negative Urgency
Um, M., Whitt, Z. T., Revilla, R., Hunton, T., & Cyders, M. A. (2019) · Brain Sciences · doi:10.3390/brainsci9020036 · Cited by 53
Addiction, Adolescence, and Innate Immune Gene Induction
Crews, F. T., & Vetreno, R. P. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00019 · Cited by 52
Common structural correlates of trait impulsiveness and perceptual reasoning in adolescence
Schilling, C., Kühn, S., Romanowski, A., Banaschewski, T., Barbot, A., Barker, G. J., Brühl, R., Büchel, C., Charlet, K., Conrod, P., et al. (2011) · Human Brain Mapping · doi:10.1002/hbm.21446 · Cited by 53
Immune function genes, genetics, and the neurobiology of addiction
Crews, F. T. (2012) · Alcohol research · doi:10.35946/arcr.v34.3.11 · Cited by 52
The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague–Dawley rats of different ages
Warneke, W., Klaus, S., Fink, H., Langley‐Evans, S. C., & Voigt, J. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.11.016 · Cited by 56
Your Resting Brain CAREs about Your Risky Behavior
Cox, C. L., Gotimer, K., Roy, A. K., Castellanos, F. X., Milham, M. P., & Kelly, C. A. M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012296 · Cited by 59
Association between P3 event‐related brain potential amplitude and adolescent problem behavior
Iacono, W. G., & McGue, M. K. (2006) · Psychophysiology · doi:10.1111/j.1469-8986.2006.00422.x · Cited by 57
A Computational Model of Craving and Obsession
Redish, A. D., & Johnson, A. C. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1390.014 · Cited by 50
Social Antecedents to the Development of Interoception: Attachment Related Processes Are Associated With Interoception
Oldroyd, K., Pasupathi, M., & Wainryb, C. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.00712 · Cited by 50
Increased Toll‐like Receptor‐MyD88‐NFκB‐Proinflammatory neuroimmune signaling in the orbitofrontal cortex of humans with alcohol use disorder
Vetreno, R. P., Qin, L., Coleman, L. G., & Crews, F. T. (2021) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14669 · Cited by 50
Caught in the Net: Perineuronal Nets and Addiction
Slaker, M. L., Blacktop, J. M., & Sorg, B. A. (2016) · Neural Plasticity · doi:10.1155/2016/7538208 · Cited by 52
The Correlation between the Frontostriatal Network and Impulsivity in Internet Gaming Disorder
Kim, J.-Y., Chun, J., Park, C.-H., Cho, H., Choi, J., Yang, S., Ahn, K. J., & Kim, D. (2019) · Scientific Reports · doi:10.1038/s41598-018-37702-4 · Cited by 50
Behavioral Economic Considerations of Novel Addictions and Nonaddictive Behavior: Research and Analytic Methods
Reed, D. D., Naudé, G. P., Gelino, B. W., & Amlung, M. T. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.011 · Cited by 48
Listening to Our Clients: The Prevention of Relapse
Levy, M. S. (2008) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2008.10400627 · Cited by 48
Independent effects of HIV infection and cocaine dependence on neurocognitive impairment in a community sample living in the southern United States
Meade, C. S., Towe, S. L., Skalski, L. M., & Robertson, K. R. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.01.034 · Cited by 48
Assessment of in vivo microstructure alterations in gray matter using DKI in internet gaming addiction
Sun, Y., Sun, J., Zhou, Y., Ding, W., Chen, X., Zhuang, Z., Xu, J., & Du, Y. (2014) · Behavioral and Brain Functions · doi:10.1186/1744-9081-10-37 · Cited by 51
The Neural Representation of Goal-Directed Actions and Outcomes in the Ventral Striatum's Olfactory Tubercle
Gadziola, M. A., & Wesson, D. W. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3328-15.2016 · Cited by 52
Long-Term High Frequency Deep Brain Stimulation of the Nucleus Accumbens Drives Time-Dependent Changes in Functional Connectivity in the Rodent Limbic System
Ewing, S. G., & Grace, A. A. (2012) · Brain stimulation · doi:10.1016/j.brs.2012.07.007 · Cited by 47
Topography, power, and current source density of theta oscillations during reward processing as markers for alcohol dependence
Kamarajan, C., Rangaswamy, M., Manz, N., Chorlian, D. B., Pandey, A. K., Roopesh, B. N., & Porjesz, B. (2011) · Human Brain Mapping · doi:10.1002/hbm.21267 · Cited by 49
Semantics vs. world knowledge in prefrontal cortex
Liina Pylkkänen, A., Oliveri, B., & Smart, A. (2009) · Language and Cognitive Processes · doi:10.1080/01690960903120176 · Cited by 48
Dopamine and Corticotropin-Releasing Factor Synergistically Alter Basolateral Amygdala-to-Medial Prefrontal Cortex Synaptic Transmission: Functional Switch after Chronic Cocaine Administration
Orozco-Cabal, L. F., Liu, J., Pollandt, S., Schmidt, K., Shinnick‐Gallagher, P., & Gallagher, J. P. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2666-07.2008 · Cited by 46
The Prevention and Treatment of Gambling Disorders: Some Art, Some Science
Derevensky, J. L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.024 · Cited by 45
Orbitofrontal and caudate volumes in cannabis users: a multi-site mega-analysis comparing dependent versus non-dependent users
Chye, Y., Solowij, N., Suo, C., Batalla, A., Cousijn, J., Goudriaan, A. E., Martín‐Santos, R., Whittle, S., Lorenzetti, V., & Yücel, M. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4606-9 · Cited by 47
Psychopathy and neurodynamic brain functioning: A review of EEG research
Clark, A. P., Bontemps, A. P., Batky, B. D., Watts, E. K., & Salekin, R. T. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.05.025 · Cited by 46
Considering the Overlap and Nonoverlap of Compulsivity, Impulsivity, and Addiction
Blum, A. W., & Grant, J. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.038 · Cited by 44
Neurobiological Foundations of Behavioral Addictions
Vaccaro, A. G., & Potenza, M. N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.016 · Cited by 45
Neurobiology of Substance Addictions
Christie, N. C., & Bechara, A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.015 · Cited by 44
Sensitization of Incentive Salience and the Transition to Addiction
Warlow, S. M., Baumgartner, H. M., Freeland, C. M., Naffziger, E. E., Olney, J. J., Berridge, K. C., & Robinson, M. J. F. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.006 · Cited by 46
Adolescent Drinking and Motivated Decision-Making: A Cotwin-Control Investigation with Monozygotic Twins
Malone, S. M., Luciana, M. M., Wilson, S., Sparks, J. C., Hunt, R. H., Thomas, K. M., & Iacono, W. G. (2014) · Behavior Genetics · doi:10.1007/s10519-014-9651-0 · Cited by 47
Mindfulness-Based Interventions Applied to Addiction Treatments
Kechter, A., & Black, D. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.040 · Cited by 43
Multiple Memory Systems, Addiction, and Health Habits: New Routes for Translational Science
Stacy, A. W., Pike, J. R., & Lee, A. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.017 · Cited by 43
Tanning as an Addiction: The State of the Research and Implications for Intervention
Miller, K. A., & Mays, D. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.037 · Cited by 43
Food versus Eating Addictions
Schulte, E. M., Schiestl, E. T., & Gearhardt, A. N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.035 · Cited by 43
Cortical regions activated by the subjective sense of perceptual coherence of environmental sounds: A proposal for a neuroscience of intuition
Volz, K. G., Rübsamen, R., & von Cramon, D. Y. (2008) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/cabn.8.3.318 · Cited by 44
Systems Level Neuroplasticity in Drug AddictionPreprint
Feltenstein, M. W., & See, R. E. (2013) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a011916 · Cited by 46
Behavioral Economics and Addictive Disorders
Jarmolowicz, D. P., & Schneider, T. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.005 · Cited by 42
Prevention and Treatment of Compulsive Buying Disorder
Galimov, A., & Black, D. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.027 · Cited by 42
Precision Behavioral Management (PBM): A Novel Genetically Guided Therapy to Combat Reward Deficiency Syndrome (RDS) Relevant to the Opiate Crisis
Blum, K., Roy, A. K., Podesta, A., Modestino, E. J., Steinberg, B., Gondré-Lewis, M. C., Baron, D. A., Thanos, P. K., Lott, L., Badgaiyan, S., et al. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.031 · Cited by 42
Prevention and Treatment of “Food Addiction”
Davis, C., & Mason, A. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.023 · Cited by 42
Human Neurobiological Approaches to Hedonically Motivated Behaviors
Burger, K. S., Shearrer, G. E., & Sadler, J. R. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.009 · Cited by 42
Feedback Models for Gambling Control: The Use and Efficacy of Online Responsible Gambling Tools
Griffiths, M. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.034 · Cited by 42
Reinforcement learning detuned in addiction: integrative and translational approaches
Groman, S. M., Thompson, S. L., Lee, D., & Taylor, J. R. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.11.007 · Cited by 40
Neuroanatomical and functional substrates of the short video addiction and its association with brain transcriptomic and cellular architecture
Gao, Y., Hu, Y., Wang, J., Liu, C., Im, H., Jin, W., Zhu, W., Ge, W., Zhao, G., Yao, Q., et al. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121029 · Cited by 43
Effects of exposure to moderate levels of ethanol during prenatal brain development on dendritic length, branching, and spine density in the nucleus accumbens and dorsal striatum of adult rats
Rice, J. P., Suggs, L. E., Lusk, A. V., Parker, M. O., Candelaria‐Cook, F. T., Akers, K. G., Savage, D. D., & Hamilton, D. A. (2012) · Alcohol · doi:10.1016/j.alcohol.2011.11.008 · Cited by 41

Authors: Schoenbaum, G., Roesch, M. R., & Stalnaker, T. A.
Affiliations: University of Maryland, Baltimore (US)
Corresponding author: Schoenbaum, Geoffrey
ORCID: Schoenbaum, Geoffrey
Roesch, Matthew R.
Stalnaker, Thomas A.
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 2006-02
Volume: 29
Issue: 2
Pages: 116-124
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/j.tins.2005.12.006
PMC: PMC2430629
OpenAlex: W2099221443
Cited by: 499
References: 95
Citations by year: 2026: 11 · 2025: 18 · 2024: 18 · 2023: 15 · 2022: 18 · 2021: 21 · 2020: 60 · 2019: 28 · 2018: 19 · 2017: 24 · 2016: 22 · 2015: 16 · 2014: 18 · 2013: 27 · 2012: 21
FWCI: 2.92
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Drug Abuse (R01DA015718)
National Institute on Deafness and Other Communication Disorders (T32 DC 00054, T32DC000054)
National Institute of Neurological Disorders and Stroke (T32 NS07375, T32NS007375)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
Keywords: orbitofrontal cortex, decision-making, drug addiction, prefrontal cortex, executive function, associative learning, basolateral amygdala, nucleus accumbens, outcome value, maladaptive decision-making
MeSH terms: Animals, Decision Making, Humans, Neural Pathways, Orbit, Prefrontal Cortex, Substance-Related Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Orbitofrontal cortex, decision-making and drug addiction

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks