Natural designer solvents for greening analytical chemistry

Novel solvent properties of choline chloride/urea mixturesElectronic supplementary information (ESI) available: spectroscopic data. See http://www.rsc.org/suppdata/cc/b2/b210714g/

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Deep eutectic solvents formed between choline chloride and carboxylic acids: Versatile alternatives to ionic liquids

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Natural deep eutectic solvents as new potential media for green technology

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Natural Deep Eutectic Solvents – Solvents for the 21st Century

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Low-transition-temperature mixtures (LTTMs): A new generation of designer solvents

Francisco, M., van den Bruinhorst, A., & Kroon, M. C. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201207548 · Cited by 1,378 · see citing works

Are Natural Deep Eutectic Solvents the Missing Link in Understanding Cellular Metabolism and Physiology?

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Tailoring properties of natural deep eutectic solvents with water to facilitate their applications

Dai, Y., Witkamp, G.-J., Verpoorte, R., & Choi, Y. H. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.03.123 · Cited by 1,367 · see citing works

Deep Eutectic Solvents: Physicochemical Properties and Gas Separation Applications

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Solubility of Metal Oxides in Deep Eutectic Solvents Based on Choline Chloride

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Natural Deep Eutectic Solvents as a New Extraction Media for Phenolic Metabolites in Carthamus tinctorius L.

Dai, Y., Witkamp, G., Verpoorte, R., & Choi, Y. H. (2013) · Analytical Chemistry · doi:10.1021/ac400432p · Cited by 682 · see citing works

Are deep eutectic solvents benign or toxic?

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Natural deep eutectic solvent mediated pretreatment of rice straw: bioanalytical characterization of lignin extract and enzymatic hydrolysis of pretreated biomass residue

Kumar, A. K., Parikh, B. S., & Pravakar, M. (2016) · Environmental Science and Pollution Research · doi:10.1007/s11356-015-4780-4 · Cited by 571 · see citing works

Freeze-Drying of Aqueous Solutions of Deep Eutectic Solvents: A Suitable Approach to Deep Eutectic Suspensions of Self-Assembled Structures

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Electrodeposition of zinc–tin alloys from deep eutectic solvents based on choline chloride

Abbott, A. P., Capper, G., McKenzie, K. J., & Ryder, K. S. (2006) · Journal of Electroanalytical Chemistry · doi:10.1016/j.jelechem.2006.04.024 · Cited by 473 · see citing works

Enhanced extraction of bioactive natural products using tailor-made deep eutectic solvents: Application to flavonoid extraction from Flos sophorae

Nam, M. W., Zhao, J., Lee, M. S., Jeong, J. H., & Lee, J. (2015) · Green Chemistry · doi:10.1039/c4gc01556h · Cited by 467 · see citing works

Green solvents for green technologies

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Ionic Liquid Analogues Formed from Hydrated Metal Salts

Abbott, A. P., Capper, G., Davies, D. L., & Rasheed, R. K. (2004) · Chemistry - A European Journal · doi:10.1002/chem.200400127 · Cited by 453 · see citing works

Natural deep eutectic solvents providing enhanced stability of natural colorants from safflower (Carthamus tinctorius)

Dai, Y., Verpoorte, R., & Choi, Y. H. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2014.02.155 · Cited by 416 · see citing works

Selective Extraction of Metals from Mixed Oxide Matrixes Using Choline-Based Ionic Liquids

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The role of green extraction techniques in Green Analytical Chemistry

Armenta, S., Garrigues, S., & de la Guardia, M. (2015) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2014.12.011 · Cited by 329 · see citing works

Electrochemistry in Deep Eutectic Solvents

Nkuku, C. A., & LeSuer, R. J. (2007) · The Journal of Physical Chemistry B · doi:10.1021/jp075794j · Cited by 309 · see citing works

Application of natural deep eutectic solvents for extraction and determination of phenolics in Cajanus cajan leaves by ultra performance liquid chromatography

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Perspectives on the replacement of harmful organic solvents in analytical methodologies: a framework toward the implementation of a generation of eco-friendly alternatives

Pena-Pereira, F., Kloskowski, A., & Namieśnik, J. (2015) · Green Chemistry · doi:10.1039/c5gc00611b · Cited by 257 · see citing works

Fast and green extraction and separation of main bioactive flavonoids from Radix Scutellariae

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Halogenation reactions in biodegradable solvent: Efficient bromination of substituted 1-aminoanthra-9,10-quinone in deep eutectic solvent (choline chloride : urea)

Phadtare, S. B., & Shankarling, G. S. (2010) · Green Chemistry · doi:10.1039/b923589b · Cited by 197 · see citing works

Deep eutectic liquid organic salt as a new solvent for liquid-phase microextraction and its application in ligandless extraction and preconcentraion of lead and cadmium in edible oils

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Organic reactions in low melting mixtures based on carbohydrates and l-carnitine—a comparison

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Environmentally benign and energy efficient methodology for condensation: an interesting facet to the classical Perkin reaction

Pawar, P. M., Jarag, K. J., & Shankarling, G. S. (2011) · Green Chemistry · doi:10.1039/c0gc00712a · Cited by 144 · see citing works

Novel zwitterionic deep eutectic solvents from trimethylglycine and carboxylic acids: characterization of their properties and their toxicity

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Electrodeposition onto magnesium in air and water stable ionic liquids: From corrosion to successful plating

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The use of ionic liquids based on choline chloride for metal deposition: A green alternative?

Haerens, K., Matthijs, E., Chmielarz, A., & der Bruggen, B. V. (2009) · Journal of Environmental Management · doi:10.1016/j.jenvman.2009.04.013 · Cited by 134 · see citing works

Coupling Cloud Point Extraction to Instrumental Detection Systems for Metal Analysis

Silva, M. F., Cerutti, E. S., & Martinez, L. D. (2006) · Microchimica Acta · doi:10.1007/s00604-006-0511-3 · Cited by 128 · see citing works

Differential capacity of a deep eutectic solvent based on choline chloride and glycerol on solid electrodes

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Separation Performance of BioRenewable Deep Eutectic Solvents

Verevkin, S. P., Sazonova, A. Y., Frolkova, A. K., Zaitsau, D. H., Prikhodko, I. V., & Held, C. (2015) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.5b00357 · Cited by 120 · see citing works

Low-melting mixtures based on choline ionic liquids

Rengstl, D., Fischer, V., & Kunz, W. (2014) · Physical Chemistry Chemical Physics · doi:10.1039/c4cp02860k · Cited by 95 · see citing works

Greener derivatization in analytical chemistry

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Synthesis of aurones under neutral conditions using a deep eutectic solvent

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A green deep eutectic solvent-based ultrasound-assisted method to extract astaxanthin from shrimp byproducts

Zhang, H., Tang, B., & Row, K. H. (2014) · Analytical Letters · doi:10.1080/00032719.2013.855783 · Cited by 64 · see citing works

Synthesis of cadmium and zinc semiconductor compounds from an ionic liquid containing choline chloride and urea

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Extraction of saponins from sisal (Agave sisalana) and juá (Ziziphus joazeiro) with cholinium-based ionic liquids and deep eutectic solvents

Ribeiro, B. D., Coelho, M. A. Z., & Marrucho, I. M. (2013) · European Food Research and Technology · doi:10.1007/s00217-013-2068-9 · Cited by 59 · see citing works

The Electrochemical Behavior and Determination of Quercetin in Choline Chloride/Urea Deep Eutectic Solvent Electrolyte Based on Abrasively Immobilized Multi-Wall Carbon Nanotubes Modified Electrode

Zheng, Y. Q., Ye, L., Yan, L., & Gao, Y. (2014) · International Journal of Electrochemical Science · doi:10.1016/s1452-3981(23)07712-x · Cited by 44 · see citing works

Enhanced performance of supercritical fluid foaming of natural‐based polymers by deep eutectic solvents

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Spectrofluorimetric and micelle-enhanced spectrofluorimetric methods for determination of Felodipine and Nimodipine in pharmaceutical preparations and human plasma

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Natural eutectic salts catalyzed one-pot synthesis of 5-arylidene-2-imino-4-thiazolidinones

Mobinikhaledi, A., & Amiri, A. K. (2012) · Research on Chemical Intermediates · doi:10.1007/s11164-012-0707-6 · Cited by 27 · see citing works

Electrochemical oxidation behavior of hydroxypivalaldehyde in the ionic liquids

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Analytical Chemistry Today and Tomorrow

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Insights into the Nature of Eutectic and Deep Eutectic Mixtures

Martins, M. A. R., Pinho, S. P., & Coutinho, J. A. P. (2018) · Journal of Solution Chemistry · doi:10.1007/s10953-018-0793-1 · Cited by 1,188 · see citing works

Deep eutectic solvents for the production and application of new materials

Tomé, L. I. N., Baião, V., da Silva, W., & Brett, C. (2018) · Applied Materials Today · doi:10.1016/j.apmt.2017.11.005 · Cited by 605 · see citing works

Review of Alternative Solvents for Green Extraction of Food and Natural Products: Panorama, Principles, Applications and Prospects

Chemat, F., Vian, M. A., Ravi, H. K., Khadhraoui, B., Hilali, S., Périno, S., & Fabiano‐Tixier, A. (2019) · Molecules · doi:10.3390/molecules24163007 · Cited by 647 · see citing works

Application of deep eutectic solvents in analytical chemistry. A review

Shishov, A., Bulatov, A., Locatelli, M., Carradori, S., & Andruch, V. (2017) · Microchemical Journal · doi:10.1016/j.microc.2017.07.015 · Cited by 561 · see citing works

Natural deep eutectic solvents for lignocellulosic biomass pretreatment: Recent developments, challenges and novel opportunities

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Green solvents from ionic liquids and deep eutectic solvents to natural deep eutectic solvents

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Metrics for green analytical chemistry

Tobiszewski, M. (2016) · Analytical Methods · doi:10.1039/c6ay00478d · Cited by 426 · see citing works

Deep eutectic solvents: An overview on their interactions with water and biochemical compounds

Achkar, T. E., Fourmentin, S., & Greige‐Gerges, H. (2019) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2019.111028 · Cited by 339 · see citing works

Structure–function relationships of deep eutectic solvents for lignin extraction and chemical transformation

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Potential use of deep eutectic solvents to facilitate lignocellulosic biomass utilization and conversion

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Sustainable synthesis of natural deep eutectic solvents (NADES) by different methods

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Sustainable green solvents and techniques for lipid extraction from microalgae: A review

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Natural deep eutectic solvents-mediated extractions: the way forward for sustainable analytical developments

Fernández, M. D. L. Á., Boiteux, J., Espino, M., Gomez, F. J. V., & Silva, M. F. (2018) · Analytica Chimica Acta · doi:10.1016/j.aca.2018.07.059 · Cited by 307 · see citing works

Deep Eutectic Solvents for Pretreatment, Extraction, and Catalysis of Biomass and Food Waste

Kalhor, P., & Ghandi, K. (2019) · Molecules · doi:10.3390/molecules24224012 · Cited by 305 · see citing works

Deep eutectic solvents. The new generation of green solvents in analytical chemistry

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Database of deep eutectic solvents and their physical properties: A review

Omar, K. A., & Sadeghi, R. (2023) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2023.121899 · Cited by 286 · see citing works

Review of ultrasound combinations with hybrid and innovative techniques for extraction and processing of food and natural products

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Novel approaches mediated by tailor-made green solvents for the extraction of phenolic compounds from agro-food industrial by-products

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Natural Deep Eutectic Solvents (NADES) as a Tool for Bioavailability Improvement: Pharmacokinetics of Rutin Dissolved in Proline/Glycine after Oral Administration in Rats: Possible Application in Nutraceuticals

Faggian, M., Sut, S., Perissutti, B., Baldan, V., Grabnar, I., & Dall’Acqua, S. (2016) · Molecules · doi:10.3390/molecules21111531 · Cited by 237 · see citing works

Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material

Ivanović, M., Razboršek, M. I., & Kolar, M. (2020) · Plants · doi:10.3390/plants9111428 · Cited by 236 · see citing works

Modern Developmental Aspects in the Field of Economical Harvesting and Biodiesel Production from Microalgae Biomass

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Deep eutectic solvent and inorganic salt pretreatment of lignocellulosic biomass for improving xylose recovery

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Optimization and modeling of microwave-assisted extraction of curcumin and antioxidant compounds from turmeric by using natural deep eutectic solvents

Doldolova, K., Bener, M., Lalikoğlu, M., Aşçı, Y. S., Arat, R., & Apak, R. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.129337 · Cited by 209 · see citing works

Effect of Water on a Hydrophobic Deep Eutectic Solvent

Kivelä, H., Salomäki, M., Vainikka, P. A., Mäkilä, E. M., Poletti, F., Ruggeri, S., Terzi, F., & Lukkari, J. (2022) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.1c08170 · Cited by 204 · see citing works

Novel extraction of polyphenols from sour cherry pomace using natural deep eutectic solvents – Ultrafast microwave-assisted NADES preparation and extraction

Popović, B. M., Mićić, N., Potkonjak, A., Blagojević, B., Pavlović, K., Milanov, D. S., & Jurić, T. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.130562 · Cited by 204 · see citing works

Choline-based deep eutectic solvents for CO2 separation: Review and thermodynamic analysis

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NMR study of choline chloride-based deep eutectic solvents

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Sustainable extraction bioactive compounds procedures in medicinal plants based on the principles of green analytical chemistry: A review

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A Greener Approach to Prepare Natural Deep Eutectic Solvents

Gómez, F. J. V., Espino, M., Fernández, M. A., & Silva, M. F. (2018) · ChemistrySelect · doi:10.1002/slct.201800713 · Cited by 183 · see citing works

Choline chloride-lactic acid deep eutectic solvent for delignification and nanocellulose production of moso bamboo

Liu, Q., Yuan, T., Fu, Q.-J., Bai, Y., Peng, F., & Yao, C. (2019) · Cellulose · doi:10.1007/s10570-019-02726-0 · Cited by 181 · see citing works

Understanding the Formation of Deep Eutectic Solvents: Betaine as a Universal Hydrogen Bond Acceptor

Abranches, D. O., Silva, L. P., Martins, M. A. R., Pinho, S. P., & Coutinho, J. A. P. (2020) · ChemSusChem · doi:10.1002/cssc.202001331 · Cited by 184 · see citing works

Deep eutectic solvents and applications in electrochemical sensing

Brett, C. M. A. (2018) · Current Opinion in Electrochemistry · doi:10.1016/j.coelec.2018.05.016 · Cited by 176 · see citing works

Hexafluoroisopropanol-based hydrophobic deep eutectic solvents for dispersive liquid-liquid microextraction of pyrethroids in tea beverages and fruit juices

Deng, W., Yu, L., Li, X., Chen, J., Wang, X., Deng, Z., & Xiao, Y. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2018.09.048 · Cited by 168 · see citing works

Green and efficient extraction of four bioactive flavonoids from Pollen Typhae by ultrasound-assisted deep eutectic solvents extraction

Meng, Z., Zhao, J., Duan, H., Guan, Y., & Zhao, L. (2018) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2018.08.048 · Cited by 167 · see citing works

Hydrophobic deep eutectic solvents for the extraction of organic and inorganic analytes from aqueous environments

Lee, J., Jung, D., & Park, K.-B. (2019) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2019.07.008 · Cited by 167 · see citing works

Towards Substitution of Hexane as Extraction Solvent of Food Products and Ingredients with No Regrets

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Deep eutectic solvents in liquid-phase microextraction: Contribution to green chemistry

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Evaluation of fatty acid/alcohol-based hydrophobic deep eutectic solvents as media for extracting antibiotics from environmental water

Tang, W., Dai, Y., & Row, K. H. (2018) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-018-1346-6 · Cited by 148 · see citing works

Physicochemical Properties, Cytotoxicity, and Antioxidative Activity of Natural Deep Eutectic Solvents Containing Organic Acid

Mitar, A., Panić, M., Radošević, K., Redovniković, I. R., Kučan, K. Z., Sander, A., Halambek, J., & Kardum, J. P. (2019) · Chemical and Biochemical Engineering Quarterly · doi:10.15255/cabeq.2018.1454 · Cited by 151 · see citing works

Deep eutectic solvents as new media for green extraction of food proteins: Opportunity and challenges

Zhou, Y., Wu, W., Zhang, N., Soladoye, O. P., Zhang, Y., & Fu, Y. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111842 · Cited by 150 · see citing works

Biobased natural deep eutectic system as versatile solvents: Structure, interaction and advanced applications

Usmani, Z., Sharma, M., Tripathi, M., Lukk, T., Karpichev, Y., Gathergood, N., Singh, B. N., Thakur, V. K., Tabatabaei, M., & Gupta, V. K. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.163002 · Cited by 145 · see citing works

Deep eutectic solvents: designer fluids for chemical processes

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Natural deep eutectic systems as alternative nontoxic cryoprotective agents

Castro, V. I. B., Craveiro, R., Silva, J. M., Reis, R. L., Paiva, A., & C. Duarte, A. R. (2018) · Cryobiology · doi:10.1016/j.cryobiol.2018.06.010 · Cited by 136 · see citing works

The NADES glyceline as a potential Green Solvent: A comprehensive study of its thermophysical properties and effect of water inclusion

Lapeña, D., Lomba, L., Artal, M., Lafuente, C., & Giner, B. (2019) · The Journal of Chemical Thermodynamics · doi:10.1016/j.jct.2018.07.031 · Cited by 129 · see citing works

The evaluation of phenolic content, in vitro antioxidant and antibacterial activity of Mentha piperita extracts obtained by natural deep eutectic solvents

Jurić, T., Mićić, N., Potkonjak, A., Milanov, D. S., Dodić, J., Trivunović, Z., & Popović, B. M. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.130226 · Cited by 129 · see citing works

Physical properties of seven deep eutectic solvents based on l-proline or betaine

Sánchez, P. B., González, B., Salgado, J., Parajó, J. J., & Domínguez, Á. (2018) · The Journal of Chemical Thermodynamics · doi:10.1016/j.jct.2018.12.017 · Cited by 123 · see citing works

Toxicity test profile for deep eutectic solvents: A detailed review and future prospects

Sharma, A., & Lee, B. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2023.141097 · Cited by 125 · see citing works

Natural Deep Eutectic Solvents (NADES) to Enhance Berberine Absorption: An In Vivo Pharmacokinetic Study

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Valorization of Tomato Waste as a Source of Carotenoids

Trombino, S., Cassano, R., Procopio, D., Gioia, M. L. D., & Barone, E. (2021) · Molecules · doi:10.3390/molecules26165062 · Cited by 118 · see citing works

Greener organic solvents in analytical chemistry

Tobiszewski, M., & Namieśnik, J. (2017) · Current Opinion in Green and Sustainable Chemistry · doi:10.1016/j.cogsc.2017.03.002 · Cited by 114 · see citing works

A grand avenue to integrate deep eutectic solvents into biomass processing

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Physicochemical and thermal characteristics of choline chloride-based deep eutectic solvents

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Unveil the Anticancer Potential of Limomene Based Therapeutic Deep Eutectic Solvents

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Choline Chloride-Based DES as Solvents/Catalysts/Chemical Donors in Pharmaceutical Synthesis

Amoroso, R., Hollmann, F., & Maccallini, C. (2021) · Molecules · doi:10.3390/molecules26206286 · Cited by 114 · see citing works

Deep eutectic solvents: Recent advances in fabrication approaches and pharmaceutical applications

Liu, Y., Wu, Y., Liu, J., Wang, W., Yang, Q., & Yang, G. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121811 · Cited by 111 · see citing works

Ecofriendly Mechanochemical Extraction of Bioactive Compounds from Plants with Deep Eutectic Solvents

Wang, M., Wang, J., Zhou, Y., Zhang, M., Xia, Q., Bi, W., & Chen, D. D. Y. (2017) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.7b01378 · Cited by 107 · see citing works

What is next? the greener future of solid liquid extraction of biobased compounds: Novel techniques and solvents overpower traditional ones

Didion, Y. P., Tjalsma, T. G., Su, Z., Malankowska, M., & Pinelo, M. (2023) · Separation and Purification Technology · doi:10.1016/j.seppur.2023.124147 · Cited by 107 · see citing works

An overview of advances in dispersive liquid–liquid microextraction for the extraction of pesticides and emerging contaminants from environmental samples

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Research Progress on the Preparation and Action Mechanism of Natural Deep Eutectic Solvents and Their Application in Food

Wu, K., Ren, J., Wang, Q., Nuerjiang, M., Xia, X., & Bian, C. (2022) · Foods · doi:10.3390/foods11213528 · Cited by 106 · see citing works

Magnetic deep eutectic solvents in microextraction techniques

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Enhanced Conversion of Xylan into Furfural using Acidic Deep Eutectic Solvents with Dual Solvent and Catalyst Behavior

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A Theoretical Study on Terpene‐Based Natural Deep Eutectic Solvent: Relationship between Viscosity and Hydrogen‐Bonding Interactions

Fan, C., Liu, Y., Sebbah, T., & Cao, X. (2021) · Global Challenges · doi:10.1002/gch2.202000103 · Cited by 97 · see citing works

Innovative Approaches for Recovery of Phytoconstituents from Medicinal/Aromatic Plants and Biotechnological Production

Fierăscu, R. C., Fierăscu, I., Orțan, A., Georgiev, M. I., & Sieniawska, E. (2020) · Molecules · doi:10.3390/molecules25020309 · Cited by 99 · see citing works

Sustainable approach for lycopene extraction from tomato processing by-product using hydrophobic eutectic solvents

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Hydrophobic deep eutectic solvents as attractive media for low-concentration hydrophobic VOC capture

Chen, C.-C., Huang, Y.-H., HUNG, S. ‐., Chen, C.-Y., Lin, C., & Yang, H. (2021) · Chemical Engineering Journal · doi:10.1016/j.cej.2021.130420 · Cited by 95 · see citing works

Natural deep eutectic solvents as new green solvents to extract anthraquinones from Rheum palmatum L.

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Enhanced electrochemical detection of quercetin by Natural Deep Eutectic Solvents

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Extraction of Natural Fragrance Ingredients: History Overview and Future Trends

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Choline chloride–based deep eutectic solvents (Ch-DESs) as promising green solvents for phenolic compounds extraction from bioresources: state-of-the-art, prospects, and challenges

Lu, W., & Liu, S. (2020) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-020-00753-7 · Cited by 95 · see citing works

Ultrasound-Assisted Extraction of Anthocyanins Using Natural Deep Eutectic Solvents and Their Incorporation in Edible Films

Velásquez, P., Bustos, D., Montenegro, G., & Giordano, A. (2021) · Molecules · doi:10.3390/molecules26040984 · Cited by 91 · see citing works

Selected Aspects Related to Medicinal and Aromatic Plants as Alternative Sources of Bioactive Compounds

Fierăscu, R. C., Fierăscu, I., Baroi, A. M., & Orțan, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041521 · Cited by 88 · see citing works

An overview about the extraction of heavy metals and other critical pollutants from contaminated water via hydrophobic deep eutectic solvents

Wazeer, I., Hizaddin, H. F., Hashim, M. A., & Hadj-Kali, M. K. (2022) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2022.108574 · Cited by 87 · see citing works

The application of green solvent in a biorefinery using lignocellulosic biomass as a feedstock

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Extracts of medicinal plants with natural deep eutectic solvents: enhanced antimicrobial activity and low genotoxicity

Grozdanova, T., Trusheva, B., Alipieva, K. I., Popova, M., Dimitrova, L. L., Najdenski, H. M., Zaharieva, M. M., Ilieva, Y. E., Vasileva, B., Miloshev, G. A., et al. (2020) · BMC Chemistry · doi:10.1186/s13065-020-00726-x · Cited by 82 · see citing works

Structural analysis of natural deep eutectic solvents. Theoretical and experimental study

Pisano, P. L., Espino, M., Fernández, M. D. L. Á., Silva, M. F., & Olivieri, A. C. (2018) · Microchemical Journal · doi:10.1016/j.microc.2018.08.016 · Cited by 81 · see citing works

Emergence of deep eutectic solvents (DES): chemistry, preparation, properties, and applications in biorefineries and critical materials

Mani, K. A., Kumar, L., BARRIOS, N. A., Agate, S., Mittal, A., Yarbrough, J. M., Jameel, H., Lucia, L. A., & Pal, L. (2025) · Progress in Materials Science · doi:10.1016/j.pmatsci.2025.101586 · Cited by 81 · see citing works

Application of green solvents as sorbent modifiers in sorptive-based extraction techniques for extraction of environmental pollutants

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Deep eutectic solvent–based headspace single-drop microextraction for the quantification of terpenes in spices

Triaux, Z., Petitjean, H., Marchioni, E., Boltoeva, M., & Marcic, C. (2020) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-019-02317-9 · Cited by 77 · see citing works

Deep eutectic solvents as absorbents for VOC and VOC mixtures in static and dynamic processes

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Magnetic ionic liquids as non-conventional extraction solvents for the determination of polycyclic aromatic hydrocarbons

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Green approaches for the extraction of antioxidants from eucalyptus leaves

Gullón, B., Muñiz‐Mouro, A., Lu-Chau, T. A., Moreira, M. T., Lema, J. M., & Eibes, G. (2019) · Industrial Crops and Products · doi:10.1016/j.indcrop.2019.111473 · Cited by 73 · see citing works

Application of a computational model of natural deep eutectic solvents utilizing the COSMO-RS approach for screening of solvents with high solubility of rutin

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A Review of the Use of Eutectic Solvents, Terpenes and Terpenoids in Liquid–liquid Extraction Processes

Rodríguez-Llorente, D., Cañada-Barcala, A., Álvarez-Torrellas, S., Águeda, V. I., Garcı́a, J., & Larriba, M. (2020) · Processes · doi:10.3390/pr8101220 · Cited by 74 · see citing works

Shedding Light on Lipase Stability in Natural Deep Eutectic Solvents

Elgharbawy, A. A. M. (2018) · Chemical and Biochemical Engineering Quarterly · doi:10.15255/cabeq.2018.1335 · Cited by 70 · see citing works

Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis

Funari, C. S., Sutton, A. T., Carneiro, R. L., Fraige, K., Cavalheiro, A. J., Bolzani, V. D. S., Hilder, E. F., & Arrua, R. D. (2019) · Food Research International · doi:10.1016/j.foodres.2019.108559 · Cited by 70 · see citing works

Antimicrobial potential of natural deep eutectic solvents

Al‐Akayleh, F., Khalid, R. M., Hawash, D., Al-Kaissi, E. N., Al-Adham, I. S. I., Al‐Muhtaseb, N., Jaber, N., Al-Remawi, M. M., & Collier, P. J. (2022) · Letters in Applied Microbiology · doi:10.1111/lam.13699 · Cited by 69 · see citing works

Synthesis of natural deep eutectic solvents using a mixture design for extraction of animal and plant samples prior to ICP-MS analysis

Santana, A. P. R., Andrade, D. F., Guimarães, T. G. S., Amaral, C. D. B., Oliveira, A., & Gonzalez, M. H. (2020) · Talanta · doi:10.1016/j.talanta.2020.120956 · Cited by 69 · see citing works

A Green Extraction Process for Polyphenols from Elderberry (Sambucus nigra) Flowers Using Deep Eutectic Solvent and Ultrasound-Assisted Pretreatment

Kaltsa, O., Lakka, A., Grigorakis, S., Karageorgou, I., Batra, G., Bozinou, E., Lalas, S. I., & Makris, D. P. (2020) · Molecules · doi:10.3390/molecules25040921 · Cited by 70 · see citing works

Towards eco-friendly crop protection: natural deep eutectic solvents and defensive secondary metabolites

Mouden, S., Klinkhamer, P. G. L., Choi, Y. H., & Leiss, K. A. (2017) · Phytochemistry Reviews · doi:10.1007/s11101-017-9502-8 · Cited by 67 · see citing works

All-fatty acid hydrophobic deep eutectic solvents towards a simple and efficient microextraction method of toxic industrial dyes

Arcon, D. P., & Franco, F. C. (2020) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2020.114220 · Cited by 61 · see citing works

Natural deep eutectic solvents as the major mobile phase components in high-performance liquid chromatography—searching for alternatives to organic solvents

Sutton, A. T., Fraige, K., Leme, G. M., Bolzani, V. D. S., Hilder, E. F., Cavalheiro, A. J., Arrua, R. D., & Funari, C. S. (2018) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-018-1027-5 · Cited by 66 · see citing works

Elaboration and Characterization of Natural Deep Eutectic Solvents (NADESs): Application in the Extraction of Phenolic Compounds from pitaya

Pires, I. V., SAKURAI, Y. C. N., Ferreira, N. R., Moreira, S. G. C., Rodrigues, A. M. D. C., & da Silva, L. H. M. (2022) · Molecules · doi:10.3390/molecules27238310 · Cited by 69 · see citing works

Green analytical chemistry metrics: Towards a sustainable phenolics extraction from medicinal plants

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Development of a deep eutectic solvent-based matrix solid phase dispersion methodology for the determination of aflatoxins in crops

Wu, X., Zhang, X., Yang, Y., Liu, Y., & Chen, X. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2019.04.030 · Cited by 61 · see citing works

Advances of responsive deep eutectic solvents and application in extraction and separation of bioactive compounds

Zhang, M., Zhang, Z., Gul, Z., Tian, M., Wang, J., Zheng, K., Zhao, C., & Li, C. (2023) · Journal of Separation Science · doi:10.1002/jssc.202300098 · Cited by 61 · see citing works

Synthesis and characterization of green menthol-based low transition temperature mixture with tunable thermophysical properties as hydrophobic low viscosity solvent

Mat Hussin, S. A., Varanusupakul, P., Shahabuddin, S., Yih Hui, B., & Mohamad, S. (2020) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2020.113015 · Cited by 60 · see citing works

Natural deep eutectic solvents for sample preparation prior to elemental analysis by plasma-based techniques

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Natural Deep Eutectic Solvents in Extraction Process

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Investigation of deep eutectic solvents as additives to β ‐CD for enantiomeric separations of Zopiclone, Salbutamol, and Amlodipine by CE

Yi, M., Wu, X., Huang, Y., & Liu, Z. (2019) · Electrophoresis · doi:10.1002/elps.201900067 · Cited by 59 · see citing works

Functional materials in chiral capillary electrophoresis

Zhang, Q., Xue, S., Li, A., & Ren, S. (2021) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2021.214108 · Cited by 58 · see citing works

Natural Deep Eutectic Solvents – Solvents for the 21st Century

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Natural Deep Eutectic Solvents (NADES): Manufacture, Characteristics, and Their Significance as Designer Solvents

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Research on the Design and Application of Natural Deep Eutectic Solvents

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Natural deep eutectic solvents as new potential media for green technology

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Green solvents from ionic liquids and deep eutectic solvents to natural deep eutectic solvents

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