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Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases

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Vegeto, Elisabetta, Benedusi, Valeria, Maggi, Adriana·2008·Frontiers in Neuroendocrinology

DOI 10.1016/j.yfrne.2008.04.001

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“Finally, using mice carrying a deletion in the gene coding for NADPH oxidase, one major source of intracellular ROS, or in Mac-1 it has been possible to clearly demonstrate that the production of ROS by LPSactivated microglia is directly toxic to neurons as well as the secretion of proinflammatory molecules, which fos…”
Sex steroids, APOE genotype and the innate immune system
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Estrogens, Neuroinflammation, and Neurodegeneration
Villa, A., Vegeto, E., Poletti, A., & Maggi, A. (2016) · Endocrine Reviews · doi:10.1210/er.2016-1007 · Cited by 423
Self-citation
Estradiol or genistein prevent Alzheimer's disease-associated inflammation correlating with an increase PPARγ expression in cultured astrocytes
Valles, S. L., Dolz-Gaiton, P., Gambini, J., Borras, C., LLoret, A., Pallardo, F. V., & Viña, J. (2010) · Brain Research · doi:10.1016/j.brainres.2009.11.044 · Cited by 186
Hormone Therapy in Menopause: Concepts, Controversies, and Approach to Treatment
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Endocrine consequences of opioid therapy
Aloisi, A. M., Aurilio, C., Bachiocco, V., Biasi, G., Fiorenzani, P., Pace, M. C., Paci, V., Pari, G., Passavanti, G., Ravaioli, L., et al. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.05.013 · Cited by 107
Rapid Signaling of Estrogen to WAVE1 and Moesin Controls Neuronal Spine Formation via the Actin Cytoskeleton
Sanchez, A. M., Flamini, M. I., Fu, X.-D., Mannella, P., Giretti, M. S., Goglia, L., Genazzani, A. R., & Simoncini, T. (2009) · Molecular Endocrinology · doi:10.1210/me.2008-0408 · Cited by 86

See all 355

Authors: Vegeto, E., Benedusi, V., & Maggi, A.
Venue: Frontiers in Neuroendocrinology
Publisher: Elsevier BV
Published: 2008-10
Volume: 29
Issue: 4
Pages: 507-519
ISSN: 0091-3022 (ISSN-L)
DOI: 10.1016/j.yfrne.2008.04.001
OpenAlex: W2063165012
Cited by: 355
References: 46
FWCI: 8.80
Type: journal article
Language: en
Open access: green

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Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases

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