Engineering cyanobacteria for photosynthetic production of 3-hydroxybutyrate directly from CO2

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Livak, K. J., & Schmittgen, T. D. (2001) · Methods · doi:10.1006/meth.2001.1262 · Cited by 180,860 · see citing works

Biodiesel from microalgae

Chisti, Y. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.02.001 · Cited by 9,524 · see citing works

Generic Assignments, Strain Histories and Properties of Pure Cultures of Cyanobacteria

Rippka, R., Stanier, R. Y., Deruelles, J., Herdman, M., & Waterbury, J. B. (1979) · Microbiology · doi:10.1099/00221287-111-1-1 · Cited by 7,606 · see citing works

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. Strain PCC6803. II. Sequence Determination of the Entire Genome and Assignment of Potential Protein-coding Regions (Supplement)

Kaneko, T., Sato, S., Kotani, H., Tanaka, A., Asamizu, E., Nakamura, Y., Miyajima, N., Hirosawa, M., Sugiura, M., Sasamoto, S., et al. (1996) · DNA Research · doi:10.1093/dnares/3.3.185 · Cited by 2,434 · see citing works

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. Strain PCC6803. II. Sequence Determination of the Entire Genome and Assignment of Potential Protein-coding Regions

Kaneko, T., Sato, S., Kotani, H., Tanaka, A., Asamizu, E., Nakamura, Y., Miyajima, N., Hirosawa, M., Sugiura, M., Sasamoto, S., et al. (1996) · DNA Research · doi:10.1093/dnares/3.3.109 · Cited by 2,132 · see citing works

Metabolic Engineering of Poly(3-Hydroxyalkanoates): From DNA to Plastic

Madison, L. L., & Huisman, G. W. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.1.21-53.1999 · Cited by 1,598 · see citing works

Codon usage tabulated from international DNA sequence databases: status for the year 2000

Nakamura, Y. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.1.292 · Cited by 1,259 · see citing works

Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde

Atsumi, S., Higashide, W., & Liao, J. C. (2009) · Nature Biotechnology · doi:10.1038/nbt.1586 · Cited by 870 · see citing works

Genome sequence of the bioplastic-producing “Knallgas” bacterium Ralstonia eutropha H16

Pohlmann, A., Fricke, W. F., Reinecke, F., Kusian, B., Liesegang, H., Cramm, R., Eitinger, T., Ewering, C., Pötter, M., Schwartz, E., et al. (2006) · Nature Biotechnology · doi:10.1038/nbt1244 · Cited by 662 · see citing works

Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism

Lindberg, P., Park, S., & Melis, A. (2010) · Metabolic Engineering · doi:10.1016/j.ymben.2009.10.001 · Cited by 596 · see citing works

Polymer synthesis by microorganisms: technology and economics

Byrom, D. (1987) · Trends in biotechnology · doi:10.1016/0167-7799(87)90100-4 · Cited by 548 · see citing works

Fatty acid production in genetically modified cyanobacteria

Liu, X., Sheng, J., & Curtiss III, R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103014108 · Cited by 532 · see citing works

Engineering cyanobacteria to generate high-value products

Ducat, D. C., Way, J. C., & Silver, P. A. (2011) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.12.003 · Cited by 507 · see citing works

Biological hydrogen production: prospects and challenges

Lee, H., Vermaas, W. F. J., & Rittmann, B. E. (2010) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.01.007 · Cited by 442 · see citing works

Metabolic engineering of cyanobacteria for 1-butanol production from carbon dioxide

Lan, E. I., & Liao, J. C. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.04.004 · Cited by 382 · see citing works

ATP drives direct photosynthetic production of 1-butanol in cyanobacteria

Lan, E. I., & Liao, J. C. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200074109 · Cited by 366 · see citing works

Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli

Inui, M., Suda, M., Kimura, S., Yasuda, K., Suzuki, H., Toda, H., Yamamoto, S., Okino, S., Suzuki, N., & Yukawa, H. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-007-1257-5 · Cited by 354 · see citing works

Mapping photoautotrophic metabolism with isotopically nonstationary 13C flux analysis

Young, J. D., Shastri, A. A., Stephanopoulos, G. N., & Morgan, J. A. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.08.002 · Cited by 347 · see citing works

Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers

Jung, Y. K., Kim, T. Y., Park, S. J., & Lee, S. Y. (2009) · Biotechnology and Bioengineering · doi:10.1002/bit.22548 · Cited by 294 · see citing works

Engineering Cyanobacteria To Synthesize and Export Hydrophilic Products

Niederholtmeyer, H., Wolfstädter, B. T., Savage, D. F., Silver, P. A., & Way, J. C. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00202-10 · Cited by 243 · see citing works

Synthetic Biology in Cyanobacteria

Heidorn, T., Camsund, D., Huang, H.-H., Lindberg, P., Oliveira, P., Stensjö, K., & Lindblad, P. C. (2011) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-385075-1.00024-x · Cited by 235 · see citing works

Genetic tools for cyanobacteria

Koksharova, O. A. (2002) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-001-0864-9 · Cited by 228 · see citing works

Biosynthesis and characterization of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Alcaligenes eutrophus

Doi, Y., Segawa, A., & Kunioka, M. (1990) · International Journal of Biological Macromolecules · doi:10.1016/0141-8130(90)90061-e · Cited by 223 · see citing works

Application of synthetic biology in cyanobacteria and algae

Wang, B., Wang, J., Zhang, W., & Meldrum, D. R. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00344 · Cited by 211 · see citing works

Production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from unrelated carbon sources by metabolically engineered Escherichia coli

Li, Z., Shi, Z., Jian, J., Guo, Y., Wu, Q., & Chen, G. (2010) · Metabolic Engineering · doi:10.1016/j.ymben.2010.03.003 · Cited by 172 · see citing works

Microbial production and applications of chiral hydroxyalkanoates

Chen, G., & Wu, Q. (2005) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-005-1917-2 · Cited by 150 · see citing works

Designing and creating a modularized synthetic pathway in cyanobacterium Synechocystis enables production of acetone from carbon dioxide

Zhou, J., Zhang, H., Zhang, Y., Li, Y., & Ma, Y. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.03.005 · Cited by 142 · see citing works

Production of poly-(3-hydroxybutyrate-co-3-hydroxyvalerate) in a recombinant Escherichia coli strain

Slater, S. C., Gallaher, T., & Dennis, D. E. (1992) · Applied and Environmental Microbiology · doi:10.1128/aem.58.4.1089-1094.1992 · Cited by 142 · see citing works

Enhanced poly-?-hydroxybutyrate accumulation in a unicellular cyanobacterium, Synechocystis sp. PCC 6803

Panda, B., & Mallick, N. (2006) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2006.02048.x · Cited by 135 · see citing works

Synechocystis sp. PCC6803 possesses a two-component polyhydroxyalkanoic acid synthase similar to that of anoxygenic purple sulfur bacteria

Hein, S., Tran, H., & Steinbüchel, A. (1998) · Archives of Microbiology · doi:10.1007/s002030050629 · Cited by 134 · see citing works

A new dawn for industrial photosynthesis

Robertson, D. E., Jacobson, S. A., Morgan, F., Berry, D., Church, G. M., & Afeyan, N. B. (2011) · Photosynthesis Research · doi:10.1007/s11120-011-9631-7 · Cited by 126 · see citing works

Metabolic Engineering of Escherichia coli for Enhanced Production of ( R )- and ( S )-3-Hydroxybutyrate

Tseng, H.-C., Martin, C. H., Nielsen, D. R., & Prather, K. L. J. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.02667-08 · Cited by 121 · see citing works

Requirement of the Nitrogen Starvation-Induced Protein Sll0783 for Polyhydroxybutyrate Accumulation in Synechocystis sp. Strain PCC 6803

Schlebusch, M., & Forchhammer, K. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00484-10 · Cited by 121 · see citing works

Biotechnological production of (R)-3-hydroxybutyric acid monomer

TOKIWA, Y., & Ugwu, C. U. (2007) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2007.03.015 · Cited by 115 · see citing works

Accumulation of poly-β-hydroxybutyrate in cyanobacterium Synechocystis sp. PCC6803

Wu, G., Wu, Q., & Shen, Z. Y. (2001) · Bioresource Technology · doi:10.1016/s0960-8524(00)00099-7 · Cited by 115 · see citing works

Metabolic Engineering of a Novel Propionate-Independent Pathway for the Production of Poly(3-Hydroxybutyrate- co -3-Hydroxyvalerate) in Recombinant Salmonella enterica Serovar Typhimurium

Aldor, I. S., Kim, S.-W., Prather, K. L. J., & Keasling, J. D. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.8.3848-3854.2002 · Cited by 115 · see citing works

Enatiomerically pure hydroxycarboxylic acids: current approaches and future perspectives

Ren, Q., Ruth, K., Thöny-Meyer, L., & Zinn, M. (2010) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-010-2530-6 · Cited by 113 · see citing works

Photosynthetic accumulation of poly-(hydroxybutyrate) by cyanobacteria—the metabolism and potential for CO2 recycling

Asada, Y., Miyake, M., Miyake, J., Kurane, R., & Tokiwa, Y. (1999) · International Journal of Biological Macromolecules · doi:10.1016/s0141-8130(99)00013-6 · Cited by 105 · see citing works

Production in Escherichia coli of Poly(3-Hydroxybutyrate- co -3-Hydroxyvalerate) with Differing Monomer Compositions from Unrelated Carbon Sources

Chen, Q., Wang, Q., Wei, G., Liang, Q., & Qi, Q. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.00091-11 · Cited by 103 · see citing works

Nickel-inducible lysis system in Synechocystis sp. PCC 6803

Liu, X., & Curtiss, R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911953106 · Cited by 97 · see citing works

Identification and Analysis of the Polyhydroxyalkanoate-Specific β-Ketothiolase and Acetoacetyl Coenzyme A Reductase Genes in the Cyanobacterium Synechocystis sp. Strain PCC6803

Taroncher‐Oldenburg, G., Nishina, K. A., & Stephanopoulos, G. N. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.10.4440-4448.2000 · Cited by 89 · see citing works

A conjugative plasmid vector for promoter analysis in several cyanobacteria of the genera Synechococcus and Synechocystis

Marraccini, P., Bulteau, S., Cassier‐Chauvat, C., Mermet-Bouvier, P., & Chauvat, F. (1993) · Plant Molecular Biology · doi:10.1007/bf00021546 · Cited by 87 · see citing works

RT-qPCR based quantitative analysis of gene expression in single bacterial cells

Gao, W., Zhang, W., & Meldrum, D. R. (2011) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2011.03.008 · Cited by 86 · see citing works

Global Transcriptional Response of the Alkali-Tolerant Cyanobacterium Synechocystis sp. Strain PCC 6803 to a pH 10 Environment

Summerfield, T. C., & Sherman, L. A. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00883-08 · Cited by 83 · see citing works

Microbial production of R-3-hydroxybutyric acid by recombinant E. coli harboring genes of phbA, phbB, and tesB

Liu, Q., Ouyang, S.-P., Chung, A., Wu, Q., & Chen, G. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-007-1063-0 · Cited by 79 · see citing works

Metabolic Engineering of Escherichia coli for Production of Enantiomerically Pure ( R )-(−)-Hydroxycarboxylic Acids

Lee, S. Y., & Lee, Y. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.6.3421-3426.2003 · Cited by 77 · see citing works

Enhanced production of d-(−)-3-hydroxybutyric acid by recombinantEscherichia coli

Gao, H.-J., Wu, Q., & Chen, G. (2002) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2002.tb11286.x · Cited by 75 · see citing works

Poly-(R)-3-hydroxybutyrate (PHB) biosynthesis: mechanistic studies on the biological Claisen condensation catalyzed by β-ketoacyl thiolase

Masamune, S., Walsh, C. T., Sinskey, A. J., & Peoples, O. P. (1989) · Pure and Applied Chemistry · doi:10.1351/pac198961030303 · Cited by 72 · see citing works

Improved accumulation of poly-3- hydroxybutyrate by a recombinant cyanobacterium

Takahashi, H., Miyake, M., Tokiwa, Y., & Asada, Y. (1998) · Biotechnology Letters · doi:10.1023/a:1005392827791 · Cited by 62 · see citing works

Thioesterase II of Escherichia coli Plays an Important Role in 3-Hydroxydecanoic Acid Production

Zheng, Z. S., Gong, Q., Liu, T., Deng, Y., Chen, J., & Chen, G. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.7.3807-3813.2004 · Cited by 58 · see citing works

Identification of gene disruptions for increased poly‐3‐hydroxybutyrate accumulation in Synechocystis PCC 6803

Tyo, K. E. J., Jin, Y., Espinoza, F. A., & Stephanopoulos, G. N. (2009) · Biotechnology Progress · doi:10.1002/btpr.228 · Cited by 50 · see citing works

Biosynthesis of enantiopure (S)-3-hydroxybutyric acid in metabolically engineered Escherichia coli

Lee, S., Park, S. J., Lee, S. Y., & Hong, S. H. (2008) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1473-7 · Cited by 45 · see citing works

A Novel Paradigm of Fatty Acid β-Oxidation Exemplified by the Thioesterase-Dependent Partial Degradation of Conjugated Linoleic Acid That Fully Supports Growth of Escherichia coli

Nie, L., Ren, Y., Janakiraman, A., Smith, S., & Schulz, H. (2008) · Biochemistry · doi:10.1021/bi801074e · Cited by 27 · see citing works

Involvement of the AtoSCDAEB regulon in the high molecular weight poly-(R)-3-hydroxybutyrate biosynthesis in phaCAB+ Escherichia coli

Theodorou, E. C., Theodorou, M., & Kyriakidis, D. A. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.03.010 · Cited by 15 · see citing works

State of the art and perspectives in catalytic processes for CO2 conversion into chemicals and fuels: The distinctive contribution of chemical catalysis and biotechnology

Aresta, M., Dibenedetto, A., & Quaranta, E. (2016) · Journal of Catalysis · doi:10.1016/j.jcat.2016.04.003 · Cited by 346 · see citing works

Atmospheric CO2 mitigation technologies: carbon capture utilization and storage

Nocito, F., & Dibenedetto, A. (2019) · Current Opinion in Green and Sustainable Chemistry · doi:10.1016/j.cogsc.2019.10.002 · Cited by 339 · see citing works

Chasing bacterial chassis for metabolic engineering: a perspective review from classical to non‐traditional microorganisms

Calero, P., & Nikel, P. I. (2018) · Microbial Biotechnology · doi:10.1111/1751-7915.13292 · Cited by 324 · see citing works

Synthetic biology of cyanobacteria: unique challenges and opportunities

Berla, B. M., Saha, R., Immethun, C. M., Maranas, C. D., Moon, T. S., & Pakrasi, H. B. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00246 · Cited by 305 · see citing works

Metabolic engineering of cyanobacteria for the synthesis of commodity products

Angermayr, S. A., Gorchs Rovira, A., & Hellingwerf, K. J. (2015) · Trends in Biotechnology · doi:10.1016/j.tibtech.2015.03.009 · Cited by 273 · see citing works

Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability

Intasian, P., Prakinee, K., Phintha, A., Trisrivirat, D., Weeranoppanant, N., Wongnate, T., & Chaiyen, P. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00121 · Cited by 264 · see citing works

Lignocellulosic biomass as renewable feedstock for biodegradable and recyclable plastics production: A sustainable approach

Raj, T., Chandrasekhar, K., Kumar, A. N., & Kim, S. (2022) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2022.112130 · Cited by 248 · see citing works

Cyanobacteria: Promising biocatalysts for sustainable chemical production

Knoot, C. J., Ungerer, J., Wangikar, P. P., & Pakrasi, H. B. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.r117.815886 · Cited by 225 · see citing works

Engineering cyanobacteria for direct biofuel production from CO2

Savakis, P., & Hellingwerf, K. J. (2014) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2014.09.007 · Cited by 209 · see citing works

Cyanobacteria: Photoautotrophic Microbial Factories for the Sustainable Synthesis of Industrial Products

Lau, N., Matsui, M., & Abdullah, A. A. (2015) · BioMed Research International · doi:10.1155/2015/754934 · Cited by 196 · see citing works

Development of Synechocystis sp. PCC 6803 as a Phototrophic Cell Factory

Yu, Y., You, L., Liu, D., Hollinshead, W. D., Tang, Y., & Zhang, F. (2013) · Marine Drugs · doi:10.3390/md11082894 · Cited by 154 · see citing works

A synthetic, light-driven consortium of cyanobacteria and heterotrophic bacteria enables stable polyhydroxybutyrate production

Weiss, T. L., Young, E. J., & Ducat, D. C. (2017) · Metabolic Engineering · doi:10.1016/j.ymben.2017.10.009 · Cited by 152 · see citing works

Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light

Kusakabe, T., Tatsuke, T., Tsuruno, K., Hirokawa, Y., Atsumi, S., Liao, J. C., & Hanai, T. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2013.09.007 · Cited by 149 · see citing works

Enhancement of poly-3-hydroxybutyrate production in Synechocystis sp. PCC 6803 by overexpression of its native biosynthetic genes

Khetkorn, W., Incharoensakdi, A., Lindblad, P. C., & Jantaro, S. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.05.014 · Cited by 148 · see citing works

Oxygen-tolerant coenzyme A-acylating aldehyde dehydrogenase facilitates efficient photosynthetic n-butanol biosynthesis in cyanobacteria

Lan, E. I., Ro, S. Y., & Liao, J. C. (2013) · Energy & Environmental Science · doi:10.1039/c3ee41405a · Cited by 146 · see citing works

Biotechnological exploitation of microalgae

Gangl, D., Zedler, J. A. Z., Rajakumar, P. D., Ramos‐Martinez, E. M., Riseley, A. S., Włodarczyk, A., Purton, S., Sakuragi, Y., Howe, C. J., Jensen, P. E., et al. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv426 · Cited by 145 · see citing works

Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics

Obruča, S., Dvořák, P., Sedláček, P., Koller, M., Sedlář, K., Pernicová, I., & Šafránek, D. (2022) · Biotechnology Advances · doi:10.1016/j.biotechadv.2022.107906 · Cited by 135 · see citing works

Biosynthesis of platform chemical 3-hydroxypropionic acid (3-HP) directly from CO2 in cyanobacterium Synechocystis sp. PCC 6803

Wang, Y., Sun, T., Gao, X., Shi, M., Wu, L., Chen, L., & Zhang, W. (2015) · Metabolic Engineering · doi:10.1016/j.ymben.2015.10.008 · Cited by 139 · see citing works

Biomedical applications of microbially engineered polyhydroxyalkanoates: an insight into recent advances, bottlenecks, and solutions

Singh, A. K., Srivastava, J. K., Chandel, A. K., Sharma, L., Mallick, N., & Singh, S. P. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-09604-y · Cited by 136 · see citing works

Progress and challenges in producing polyhydroxyalkanoate biopolymers from cyanobacteria

Singh, A. K., Sharma, L., Mallick, N., & Mala, J. (2016) · Journal of Applied Phycology · doi:10.1007/s10811-016-1006-1 · Cited by 135 · see citing works

Metabolic design for cyanobacterial chemical synthesis

Oliver, J. W. K., & Atsumi, S. (2014) · Photosynthesis Research · doi:10.1007/s11120-014-9997-4 · Cited by 134 · see citing works

Exploring the photosynthetic production capacity of sucrose by cyanobacteria

Du, W., Liang, F., Duan, Y., Tan, X., & Lü, X. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2013.05.001 · Cited by 133 · see citing works

Growing green electricity: Progress and strategies for use of Photosystem I for sustainable photovoltaic energy conversion

Nguyen, K., & Bruce, B. D. (2014) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2013.12.013 · Cited by 132 · see citing works

Photoautotrophic production of D-lactic acid in an engineered cyanobacterium

Varman, A. M., Yu, Y., You, L., & Tang, Y. (2013) · Microbial Cell Factories · doi:10.1186/1475-2859-12-117 · Cited by 130 · see citing works

Increased Bioplastic Production with an RNA Polymerase Sigma Factor SigE during Nitrogen Starvation in Synechocystis sp. PCC 6803

Osanai, T., Numata, K., Oikawa, A., Kuwahara, A., Iijima, H., Doi, Y., Tanaka, K., Saito, K., & Hirai, M. Y. (2013) · DNA Research · doi:10.1093/dnares/dst028 · Cited by 125 · see citing works

Increased poly-β-hydroxybutyrate production from carbon dioxide in randomly mutated cells of cyanobacterial strain Synechocystis sp. PCC 6714: Mutant generation and characterization

Kamravamanesh, D., Kovács, T., Pflügl, S., Druzhinina, I. S., Kröll, P., Lackner, M. K., & Herwig, C. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.06.057 · Cited by 118 · see citing works

The integration of bio-catalysis and electrocatalysis to produce fuels and chemicals from carbon dioxide

Tan, X., & Nielsen, J. (2022) · Chemical Society Reviews · doi:10.1039/d2cs00309k · Cited by 117 · see citing works

Two-stage (photoautotrophy and heterotrophy) cultivation enables efficient production of bioplastic poly-3-hydroxybutyrate in auto-sedimenting cyanobacterium

Monshupanee, T., Nimdach, P., & Incharoensakdi, A. (2016) · Scientific Reports · doi:10.1038/srep37121 · Cited by 115 · see citing works

Cyanobacteria as a Promising Alternative for Sustainable Environment: Synthesis of Biofuel and Biodegradable Plastics

Agarwal, P., Soni, R., Kaur, P., Madan, A., Mishra, R., Pandey, J., Singh, S., & Singh, G. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.939347 · Cited by 118 · see citing works

Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production

Anfelt, J., Kaczmarzyk, D., Shabestary, K., Renberg, B., Rockberg, J., Nielsen, J., Uhlén, M., & Hudson, E. P. (2015) · Microbial Cell Factories · doi:10.1186/s12934-015-0355-9 · Cited by 113 · see citing works

Metabolic engineering of cyanobacteria for photosynthetic 3-hydroxypropionic acid production from CO2 using Synechococcus elongatus PCC 7942

Lan, E. I., Chuang, D. S., Shen, C. R., Lee, A. M., Ro, S. Y., & Liao, J. C. (2015) · Metabolic Engineering · doi:10.1016/j.ymben.2015.08.002 · Cited by 111 · see citing works

Cyanobacteria as photoautotrophic biofactories of high-value chemicals

Noreña-Caro, D., & Benton, M. G. (2018) · Journal of CO2 Utilization · doi:10.1016/j.jcou.2018.10.008 · Cited by 109 · see citing works

Photo-autotrophic Production of Poly(hydroxyalkanoates) in Cyanobacteria

Drosg, B. (2015) · Chemical and Biochemical Engineering Quarterly · doi:10.15255/cabeq.2014.2254 · Cited by 107 · see citing works

Cyanobacterial chassis engineering for enhancing production of biofuels and chemicals

Gao, X., Sun, T., Pei, G., Chen, L., & Zhang, W. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7374-2 · Cited by 106 · see citing works

A Genetic Toolbox for Modulating the Expression of Heterologous Genes in the Cyanobacterium Synechocystis sp. PCC 6803

Wang, B., Eckert, C. A., Maness, P., & Yu, J. (2017) · ACS Synthetic Biology · doi:10.1021/acssynbio.7b00297 · Cited by 99 · see citing works

Genetic engineering of Synechocystis sp. PCC6803 for poly-β-hydroxybutyrate overproduction

Carpine, R., Du, W., Olivieri, G., Pollio, A., Hellingwerf, K. J., Marzocchella, A., & dos Santos, F. B. (2017) · Algal Research · doi:10.1016/j.algal.2017.05.013 · Cited by 98 · see citing works

Advances in cyanobacterial polyhydroxyalkanoates production

Singh, A. K., & Mallick, N. (2017) · FEMS Microbiology Letters · doi:10.1093/femsle/fnx189 · Cited by 98 · see citing works

Metabolic engineering of cyanobacteria for the photosynthetic production of succinate

Lan, E. I., & Wei, C. T. (2016) · Metabolic Engineering · doi:10.1016/j.ymben.2016.10.014 · Cited by 94 · see citing works

Exploiting Polyhydroxyalkanoates for Biomedical Applications

Kalia, V. C., Patel, S. K. S., & Lee, J.-K. (2023) · Polymers · doi:10.3390/polym15081937 · Cited by 91 · see citing works

Poly(hydroxyalkanoates) for Food Packaging: Application and Attempts towards Implementation

Koller, M. (2014) · Applied food biotechnology · doi:10.22037/afb.v1i1.7127 · Cited by 90 · see citing works

Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

Lai, M. J., & Lan, E. I. (2015) · Metabolites · doi:10.3390/metabo5040636 · Cited by 90 · see citing works

Cyanobacterial biofuels: new insights and strain design strategies revealed by computational modeling

Erdrich, P., Knoop, H., Steuer, R., & Klamt, S. (2014) · Microbial Cell Factories · doi:10.1186/s12934-014-0128-x · Cited by 85 · see citing works

Tailoring cyanobacteria as a new platform for highly efficient synthesis of astaxanthin

Diao, J., Song, X., Zhang, L., Cui, J., Chen, L., & Zhang, W. (2020) · Metabolic Engineering · doi:10.1016/j.ymben.2020.07.003 · Cited by 84 · see citing works

Challenges and Perspectives of Polyhydroxyalkanoate Production From Microalgae/Cyanobacteria and Bacteria as Microbial Factories: An Assessment of Hybrid Biological System

Afreen, R., Tyagi, S., Singh, G. P., & Singh, M. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.624885 · Cited by 86 · see citing works

Ten years of algal biofuel and bioproducts: gains and pains

Chen, H., Li, T., & Wang, Q. (2019) · Planta · doi:10.1007/s00425-018-3066-8 · Cited by 83 · see citing works

Fine-Tuning of Photoautotrophic Protein Production by Combining Promoters and Neutral Sites in the Cyanobacterium Synechocystis sp. Strain PCC 6803

Ng, A. H., Berla, B. M., & Pakrasi, H. B. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.01349-15 · Cited by 83 · see citing works

Cyanobacterial polyhydroxybutyrate for sustainable bioplastic production: Critical review and perspectives

Price, S., Kuzhiumparambil, U., Pernice, M., & Ralph, P. J. (2020) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2020.104007 · Cited by 82 · see citing works

The state of autotrophic ethanol production in Cyanobacteria

Dexter, J., Armshaw, P., Sheahan, C., & Pembroke, J. T. (2015) · Journal of Applied Microbiology · doi:10.1111/jam.12821 · Cited by 81 · see citing works

Isotopically nonstationary 13C flux analysis of cyanobacterial isobutyraldehyde production

Jazmin, L. J., Xu, Y. Q., Cheah, Y. E., Adebiyi, A. O., Johnson, C. H., & Young, J. D. (2017) · Metabolic Engineering · doi:10.1016/j.ymben.2017.05.001 · Cited by 78 · see citing works

Extending the biosynthetic repertoires of cyanobacteria and chloroplasts

Nielsen, A. Z., Mellor, S. B., Vavitsas, K., Włodarczyk, A., Gnanasekaran, T., de Jesus, M. P. R. H., King, B. C., Bakowski, K., & Jensen, P. E. (2016) · The Plant Journal · doi:10.1111/tpj.13173 · Cited by 79 · see citing works

Anaerobic Production of Poly(3-hydroxybutyrate) and Its Precursor 3-Hydroxybutyrate from Synthesis Gas by Autotrophic Clostridia

Flüchter, S., Follonier, S., Schiel‐Bengelsdorf, B., Bengelsdorf, F. R., Zinn, M., & Dürre, P. (2019) · Biomacromolecules · doi:10.1021/acs.biomac.9b00342 · Cited by 78 · see citing works

From cyanochemicals to cyanofactories: a review and perspective

Zhou, J., Zhu, T., Cai, Z., & Li, Y. (2016) · Microbial Cell Factories · doi:10.1186/s12934-015-0405-3 · Cited by 78 · see citing works

Cyanobacterial production of 1,3-propanediol directly from carbon dioxide using a synthetic metabolic pathway

Hirokawa, Y., Maki, Y., Tatsuke, T., & Hanai, T. (2016) · Metabolic Engineering · doi:10.1016/j.ymben.2015.12.008 · Cited by 76 · see citing works

Polyhydroxyalkanoates in tissue repair and regeneration

Guo, W., Yang, K., Qin, X., Luo, R., Wang, H., & Huang, R. (2022) · Engineered Regeneration · doi:10.1016/j.engreg.2022.01.003 · Cited by 76 · see citing works

Algal bioplastics: current market trends and technical aspects

Nanda, N., & Bharadvaja, N. (2022) · Clean Technologies and Environmental Policy · doi:10.1007/s10098-022-02353-7 · Cited by 75 · see citing works

Molar-Based Targeted Metabolic Profiling of Cyanobacterial Strains with Potential for Biological Production

Dempo, Y., Ohta, E., Nakayama, Y., Bamba, T., & Fukusaki, E. (2014) · Metabolites · doi:10.3390/metabo4020499 · Cited by 75 · see citing works

Regulation of β-phellandrene synthase gene expression, recombinant protein accumulation, and monoterpene hydrocarbons production in Synechocystis transformants

Formighieri, C., & Melis, A. (2014) · Planta · doi:10.1007/s00425-014-2080-8 · Cited by 74 · see citing works

The plasticity of cyanobacterial carbon metabolism

Xiong, W., Cano, M., Wang, B., Douchi, D., & Yu, J. (2017) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2017.09.004 · Cited by 73 · see citing works

Sustainable production of polyhydroxybutyrate from autotrophs using CO2 as feedstock: Challenges and opportunities

Sirohi, R., Lee, J. S., Yu, B. S., Roh, H., & Sim, S. J. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.125751 · Cited by 64 · see citing works

Carbon roadmap from syngas to polyhydroxyalkanoates in R hodospirillum rubrum

Revelles, O., Tarazona, N. A., García, J. L., & Prieto, M. A. (2015) · Environmental Microbiology · doi:10.1111/1462-2920.13087 · Cited by 62 · see citing works

Recent Advances and Future Perspectives of PHB Production by Cyanobacteria

Costa, J. A. V., Moreira, J. B., Lucas, B. F., Braga, V. D. S., Cassuriaga, A. P. A., & de Morais, M. G. (2018) · Industrial Biotechnology · doi:10.1089/ind.2018.0017 · Cited by 62 · see citing works

Cyanobacteria as Photosynthetic Biocatalysts: A Systems Biology Perspective

Gudmundsson, S., & Nogales, J. (2014) · Molecular BioSystems · doi:10.1039/c4mb00335g · Cited by 61 · see citing works

Genetic engineering and metabolite profiling for overproduction of polyhydroxybutyrate in cyanobacteria

Hondo, S., Takahashi, M., Osanai, T., Matsuda, M., Hasunuma, T., Tazuke, A., Nakahira, Y., Chohnan, S., Hasegawa, M., & Asayama, M. (2015) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2015.03.004 · Cited by 61 · see citing works

Cyanobacteria: A metabolic power house for harvesting solar energy to produce bio-electricity and biofuels

Sarma, M. K., Kaushik, S., & Goswami, P. (2016) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2016.03.043 · Cited by 60 · see citing works

Cyanobacterial Polyhydroxyalkanoate Production: Status Quo and Quo Vadis?

Koller, M. (2015) · Current Biotechnology · doi:10.2174/2211550104666150917010849 · Cited by 60 · see citing works

Enhancing the light-driven production of d-lactate by engineering cyanobacterium using a combinational strategy

Li, C., Tao, F., Ni, J., Wang, Y., Yao, F., & Xu, P. (2015) · Scientific Reports · doi:10.1038/srep09777 · Cited by 59 · see citing works

Cyanobacterial chemical production

Case, A. E., & Atsumi, S. (2016) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2016.05.023 · Cited by 58 · see citing works

Photoautotrophic Polyhydroxybutyrate Granule Formation Is Regulated by Cyanobacterial Phasin PhaP in Synechocystis sp. Strain PCC 6803

Hauf, W., Watzer, B., Roos, N., Klotz, A., & Forchhammer, K. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.00604-15 · Cited by 58 · see citing works

MoS2 Nanosheets–Cyanobacteria Interaction: Reprogrammed Carbon and Nitrogen Metabolism

Chen, S., Shi, N., Huang, M., Tan, X., Yan, X., Wang, A., Huang, Y., Ji, R., Zhou, D., Zhu, Y., et al. (2021) · ACS Nano · doi:10.1021/acsnano.1c05656 · Cited by 57 · see citing works

Upcycling the anaerobic digestion streams in a bioeconomy approach: a review

Tsapekos, P., Khoshnevisan, B., Alvarado-Morales, M., Zhu, X., Pan, J., Tian, H., & Angelidaki, I. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111635 · Cited by 58 · see citing works

Current Strategies on Algae-Based Biopolymer Production and Scale-Up

Mal, N., Satpati, G., Raghunathan, S., & Davoodbasha, M. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2021.133178 · Cited by 55 · see citing works

Synthetic biology approaches for the production of plant metabolites in unicellular organisms

Moses, T., Mehrshahi, P., Smith, A. G., & Goossens, A. (2017) · Journal of Experimental Botany · doi:10.1093/jxb/erx119 · Cited by 55 · see citing works

Redirecting photosynthetic electron flux in the cyanobacterium Synechocystis sp. PCC 6803 by the deletion of flavodiiron protein Flv3

Thiel, K., Patrikainen, P., Nagy, C. I., Fitzpatrick, D., Pope, N., Aro, E., & Kallio, P. (2019) · Microbial Cell Factories · doi:10.1186/s12934-019-1238-2 · Cited by 55 · see citing works

Oxygen‐responsive genetic circuits constructed in Synechocystis sp. PCC 6803

Immethun, C. M., Ng, K. M., DeLorenzo, D. M., Waldron‐Feinstein, B., Lee, Y.-C. J., & Moon, T. S. (2015) · Biotechnology and Bioengineering · doi:10.1002/bit.25722 · Cited by 54 · see citing works

Optimization of isopropanol production by engineered cyanobacteria with a synthetic metabolic pathway

Hirokawa, Y., Suzuki, I., & Hanai, T. (2014) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2014.10.005 · Cited by 53 · see citing works

An overview on biofuel and biochemical production by photosynthetic microorganisms with understanding of the metabolism and by metabolic engineering together with efficient cultivation and downstream processing

Sarkar, D., & Shimizu, K. (2015) · Bioresources and Bioprocessing · doi:10.1186/s40643-015-0045-9 · Cited by 55 · see citing works

Enhancement of acetyl-CoA flux for photosynthetic chemical production by pyruvate dehydrogenase complex overexpression in Synechococcus elongatus PCC 7942

Hirokawa, Y., Kubo, T., Soma, Y., Saruta, F., & Hanai, T. (2019) · Metabolic Engineering · doi:10.1016/j.ymben.2019.07.012 · Cited by 53 · see citing works

Photomixotrophic chemical production in cyanobacteria

Matson, M. M., & Atsumi, S. (2017) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2017.11.008 · Cited by 52 · see citing works

A balanced ATP driving force module for enhancing photosynthetic biosynthesis of 3-hydroxybutyrate from CO2

Ku, J. T., & Lan, E. I. (2018) · Metabolic Engineering · doi:10.1016/j.ymben.2018.02.004 · Cited by 52 · see citing works

Genetic, Genomics, and Responses to Stresses in Cyanobacteria: Biotechnological Implications

Cassier‐Chauvat, C., Blanc-Garin, V., & Chauvat, F. (2021) · Genes · doi:10.3390/genes12040500 · Cited by 47 · see citing works

Unlocking the photobiological conversion of CO 2 to ( R )-3-hydroxybutyrate in cyanobacteria

Wang, B., Xiong, W., Yu, J., Maness, P., & Meldrum, D. R. (2018) · Green Chemistry · doi:10.1039/c8gc01208c · Cited by 49 · see citing works

Many ways towards ‘solar fuel’: quantitative analysis of the most promising strategies and the main challenges during scale-up

Lips, D., Schuurmans, J. M., dos Santos, F. B., & Hellingwerf, K. J. (2017) · Energy & Environmental Science · doi:10.1039/c7ee02212c · Cited by 47 · see citing works

Polyhydroxybutyrate Production by Spirulina sp. LEB 18 Grown under Different Nutrient Concentrations

Vanessa, C. C., Cleber, K. D. S., Ana, L. T., Jorge, A. V. C., & Michele, G. D. M. (2015) · African Journal of Microbiology Research · doi:10.5897/ajmr2015.7530 · Cited by 45 · see citing works

Metabolic engineering for isopropanol production by an engineered cyanobacterium, Synechococcus elongatus PCC 7942, under photosynthetic conditions

Hirokawa, Y., Dempo, Y., Fukusaki, E., & Hanai, T. (2016) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2016.07.005 · Cited by 45 · see citing works

Metabolic engineering of Synechococcus elongatus PCC 7942 for improvement of 1,3-propanediol and glycerol production based on in silico simulation of metabolic flux distribution

Hirokawa, Y., Matsuo, S., Hamada, H., Matsuda, F., & Hanai, T. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0824-4 · Cited by 45 · see citing works

Recent trends of biotechnological production of polyhydroxyalkanoates from C1 carbon sources

Ray, S., Jin, J.-O., Choi, I.-H., & Kim, M. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.907500 · Cited by 44 · see citing works

Citrate synthase from Synechocystis is a distinct class of bacterial citrate synthase

Ito, S., Koyama, N., & Osanai, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-42659-z · Cited by 44 · see citing works

Increased carbohydrate production from carbon dioxide in randomly mutated cells of cyanobacterial strain Synechocystis sp. PCC 6714: Bioprocess understanding and evaluation of productivities

Kamravamanesh, D., Slouka, C., Limbeck, A., Lackner, M. K., & Herwig, C. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.11.025 · Cited by 40 · see citing works

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

Liang, B., Sun, G., Zhang, X., Nie, Q., Zhao, Y., & Yang, J. (2022) · Biotechnology and Bioengineering · doi:10.1002/bit.28170 · Cited by 40 · see citing works

Photosynthetic green hydrogen: Advances, challenges, opportunities, and prospects

Borges, P. T., Sales, M. B., Guimarães, C. E. C., Serpa, J. D. F., de Lima, R. K. C., Lopes, A. A. S., Rios, M. A. D. S., Desai, A. S., Lima, A. M. D. S., Lora, E. E. S., et al. (2023) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2023.09.075 · Cited by 42 · see citing works

Emerging Trends of Nanotechnology and Genetic Engineering in Cyanobacteria to Optimize Production for Future Applications

Rajakumar, G., Gayathiri, E., Sankar, S., Venkidasamy, B., Prakash, P., Rekha, K., Savaner, V., Abirami, P., Thirumalaivasan, N., & Thiruvengadam, M. (2022) · Life · doi:10.3390/life12122013 · Cited by 38 · see citing works

Prerequisite for highly efficient isoprenoid production by cyanobacteria discovered through the over-expression of 1-deoxy-d-xylulose 5-phosphate synthase and carbon allocation analysis

Kudoh, K., Kawano, Y., Hotta, S., Sekine, M., Watanabe, T., & Ihara, M. (2014) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2013.12.018 · Cited by 38 · see citing works

Molecular genetic improvements of cyanobacteria to enhance the industrial potential of the microbe: A review

Johnson, T. J., Gibbons, J., Gu, L., Zhou, R., & Gibbons, W. R. (2016) · Biotechnology Progress · doi:10.1002/btpr.2358 · Cited by 38 · see citing works

Improvement of 1,3-propanediol production using an engineered cyanobacterium, Synechococcus elongatus by optimization of the gene expression level of a synthetic metabolic pathway and production conditions

Hirokawa, Y., Maki, Y., & Hanai, T. (2016) · Metabolic Engineering · doi:10.1016/j.ymben.2016.12.001 · Cited by 37 · see citing works

Production of optically pure d-lactate from CO2 by blocking the PHB and acetate pathways and expressing d-lactate dehydrogenase in cyanobacterium Synechocystis sp. PCC 6803

Zhou, J., Zhang, H., Meng, H., Zhang, Y., & Li, Y. (2014) · Process Biochemistry · doi:10.1016/j.procbio.2014.09.007 · Cited by 34 · see citing works

Acetyl-CoA-derived biofuel and biochemical production in cyanobacteria: a mini review

Choi, Y., Lee, J. W., Kim, J. W., & Park, J. M. (2020) · Journal of Applied Phycology · doi:10.1007/s10811-020-02128-x · Cited by 33 · see citing works

Premethylation of Foreign DNA Improves Integrative Transformation Efficiency in Synechocystis sp. Strain PCC 6803

Wang, B., Yu, J., Zhang, W., & Meldrum, D. R. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.02575-15 · Cited by 32 · see citing works

Construction of a novel d-lactate producing pathway from dihydroxyacetone phosphate of the Calvin cycle in cyanobacterium, Synechococcus elongatus PCC 7942

Hirokawa, Y., Goto, R., Umetani, Y., & Hanai, T. (2017) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2017.02.016 · Cited by 32 · see citing works

Engineering a Central Carbon Metabolism Pathway to Increase the Intracellular Acetyl-CoA Pool in Synechocystis sp. PCC 6803 Grown under Photomixotrophic Conditions

Song, X., Diao, J., Yao, J., Cui, J., Sun, T., Chen, L., & Zhang, W. (2021) · ACS Synthetic Biology · doi:10.1021/acssynbio.0c00629 · Cited by 30 · see citing works

An orphan two-component response regulator Slr1588 involves salt tolerance by directly regulating synthesis of compatible solutes in photosynthetic Synechocystis sp. PCC 6803

Chen, L., Wu, L., Zhu, Y., Song, Z., Wang, J., & Zhang, W. (2014) · Molecular BioSystems · doi:10.1039/c4mb00095a · Cited by 29 · see citing works

Metabolic engineering strategies of Pseudomonas putida KT2440 for biocatalysis under conditions with restricted oxygen supply

Nikel, P. I., & de Lorenzo, V. (2012) · New Biotechnology · doi:10.1016/j.nbt.2012.08.077

Engineering Cyanobacteria to Convert Carbon Dioxide to Building Blocks for Renewable Plastics

(2014) · Arizona State University Library Digital Repository (Arizona State University)

Optimizing photoautotrophic production of soluble 3-hydroxybutyrate in Synechocystis sp. PCC 6803 through combinatorial translational tuningPreprint

Kakko, L., Muth‐Pawlak, D., Patrikainen, P., Aro, E., & Kallio, P. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.09.698553

Biosynthesis of platform chemical 3-hydroxypropionic acid (3-HP) directly from CO2 in cyanobacterium Synechocystis sp. PCC 6803

Wang, Y., Sun, T., Gao, X., Shi, M., Wu, L., Chen, L., & Zhang, W. (2015) · Metabolic Engineering · doi:10.1016/j.ymben.2015.10.008 · Cited by 139 · see citing works

Metabolic engineering of cyanobacteria for photosynthetic 3-hydroxypropionic acid production from CO2 using Synechococcus elongatus PCC 7942

Lan, E. I., Chuang, D. S., Shen, C. R., Lee, A. M., Ro, S. Y., & Liao, J. C. (2015) · Metabolic Engineering · doi:10.1016/j.ymben.2015.08.002 · Cited by 111 · see citing works