Patterns of sedentary time and cardiometabolic risk among Canadian adults
Abstract
Objective The aim of this study is to examine the associations of total sedentary time and patterns of sedentary time with cardiometabolic biomarkers in a large representative sample of Canadian adults. Methods The study is based on 4935 adults aged 20-79years, from the 2007/09 and 2009/11 Canadian Health Measures Survey. Total sedentary time, patterns of sedentary time (≥20minute prolonged sedentary bouts, number of sedentary breaks), and moderate- to vigorous-intensity physical activity (MVPA) were accelerometer-derived. Waist circumference, systolic and diastolic blood pressure, high-density lipoprotein (HDL) cholesterol, and C-reactive protein were measured. Triglycerides, low-density lipoprotein (LDL) cholesterol, insulin, and glucose were also measured in a fasting sub-sample (n=2551). Results Total sedentary time and time in ≥20minute prolonged sedentary bouts were associated with higher insulin and lower diastolic blood pressure levels (P<0.05). On average, each additional 10 breaks/day was associated with 0.83 (95%CI: 1.35, 0.31) cm lower waist circumference, 0.32 (0.62, 0.02) mmHg lower systolic blood pressure, 0.01 (0.00, 0.02) mmol/l higher HDL-cholesterol, 3.72 (1.34, 6.13) % lower triglycerides, 0.57 (0.23, 0.92) % lower glucose, and 4.19 (1.80, 6.63) % lower insulin. Conclusion These findings in a large representative sample of Canadian adults indicate that breaking up sedentary time may be particularly important for cardiometabolic health.
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Each additional set of ten sedentary breaks in a day was associated with lower blood glucose by 0.57%, lower insulin by 4.19%, higher HDL cholesterol by 0.01 mmol/L, and lower waist circumference by 0.83 cm.
“Every additional set of ten sedentary breaks in a day was associated with improvements in blood glucose (0.57% lower), insulin (4.19% lower), high density lipoprotein (HDL) cholesterol (0.01 mmol/L higher), and waist circumference (0.83 cm lower).”
From The Impact of Physical Activity in Patients With Type 2 Diabetes (2025) · cites this paper as [86]
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- Authors
- Carson, V., Wong, S. L., Winkler, E., Healy, G. N., Colley, R. C., & Tremblay, M. S.
- Affiliations
- University of Alberta (CA)
- Statistics Canada (CA)
- Baker Heart and Diabetes Institute (AU)
- University of Ottawa (CA)
- Corresponding author
- Carson, Valerie
- Venue
- Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2014-08
- Volume
- 65
- Pages
- 23-27
- ISSN
- 0091-7435 (ISSN-L)
- OpenAlex
- W2067375782
- Cited by
- 172
- References
- 31
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 6 · 2023: 16 · 2022: 8 · 2021: 14 · 2020: 24 · 2019: 14 · 2018: 15 · 2017: 27 · 2016: 13 · 2015: 22 · 2014: 2
- FWCI
- 14.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- eSpace (Curtin University) (submittedVersion)
- Funders
- National Health and Medical Research Council (NHMRC) (APP1000986)
- Heart Foundation (PH 12B 7054)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- sedentary behavior, prolonged sedentary bouts, sedentary breaks, cardiometabolic risk, cardiometabolic biomarkers, insulin, blood pressure, waist circumference, HDL cholesterol, triglycerides, C-reactive protein, moderate-to-vigorous physical activity, adults
- MeSH terms
- Adult, Aged, Canada, Cardiovascular Diseases, Cross-Sectional Studies, Environmental Monitoring, Female, Health Surveys, Humans, Insulin Resistance, Male, Metabolic Diseases, Middle Aged, Motor Activity, Time Factors, Biomarkers, Risk Assessment, Young Adult, Sedentary Behavior, Accelerometry
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