The effects of objectively measured sedentary behavior on all-cause mortality in a national sample of adults with diabetes
Abstract
Background Diabetes is a highly prevalent chronic disease that has been increasing globally and is the seventh leading cause of death in the United States. Sedentary behavior is associated with increased risk of diabetes and is unfavorably related to all-cause mortality, but there are limited studies examining the sedentary-mortality relationship among those with diabetes, which was the purpose of this study.Methods Using data from the 2003-2006 NHANES, 712 adult participants with evidence of diabetes had complete data on the study variables. A multivariable Cox proportional hazard model was used to examine the association between objectively measured sedentary behavior and all-cause mortality among this diabetic sample.Results Results showed that for every 60min/day increase in sedentary behavior, independent of moderate-to-vigorous physical activity (MVPA) and other covariates, adults with diabetes had a 13% increased risk of all-cause mortality (HRadjusted=1.13; 95% CI=1.03-1.24; P=0.01). However, after adjusting for total physical activity (light and MVPA), sedentary behavior was no longer associated with mortality risk (HRadjusted=1.04; 95% CI=0.92-1.16; P=0.46).Conclusion Among those with diabetes, sedentary behavior may not have increased mortality risk independent of total physical activity behavior.
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Both physical inactivity and sedentary behavior are independently associated with increased mortality from any cause and cardiovascular disease in people with type 2 diabetes.
“and also in people with type 2 diabetes (3,4)”
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- Authors
- Loprinzi, P. D., & Sng, E.
- Affiliations
- University of Mississippi (US)
- Corresponding author
- Loprinzi, Paul D.
- ORCID
- Loprinzi, Paul D.
- Venue
- Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2016-05
- Volume
- 86
- Pages
- 55-57
- ISSN
- 0091-7435 (ISSN-L)
- OpenAlex
- W2254086521
- Cited by
- 21
- References
- 21
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 7 · 2022: 2 · 2021: 3 · 2020: 1 · 2018: 2 · 2017: 4
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- sedentary behavior, diabetes mellitus, all-cause mortality, moderate-to-vigorous physical activity, light physical activity, NHANES, mortality risk
- MeSH terms
- Diabetes Mellitus, Female, Humans, Male, Middle Aged, Nutrition Surveys, Risk Factors, United States, Exercise, Proportional Hazards Models, Sedentary Behavior, Accelerometry
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