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Association of Aortic Atherosclerosis with Cerebral β-Amyloidosis and Learning Deficits in a Mouse Model of Alzheimer's Disease
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A relationship is reported between aortic atherosclerosis and brain Aβ deposits and learning deficits in transgenic Tg2576 mice fed an atherogenic diet.
“Moreover, a relationship is reported between aortic atherosclerosis and brain Aβ deposits and learning deficits in transgenic Tg2576 mice fed an atherogenic diet [41].”
From ApoB100/LDLR-/- Hypercholesterolaemic Mice as a Model for Mild Cognitive Impairment and Neuronal Damage (2011) · cites this paper as [41]
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Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition
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“27 The mechanisms by which atherosclerosis and (cid:2) -amyloidosis are connected have not been fully understood.”
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Metadata
- Authors
- Li, L., Cao, D., Garber, D. W., Kim, H., & Fukuchi, K.-I.
- Venue
- The American Journal of Pathology
- Publisher
- Elsevier BV
- Published
- 2003-12
- Volume
- 163
- Issue
- 6
- Pages
- 2155-2164
- ISSN
- 0002-9440
- Cited by
- 105
- References
- 3
- Language
- en
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