Psychophysiological and subjective indicators of aversive pavlovian conditioning in generalized social phobia
Abstract
Aversive conditioning has been proposed as an important etiologic mechanism in social phobia; however, empirical evidence is scarce and has not relied on a detailed analysis of the acquisition and extinction of the conditioned emotional response. Fourteen men sustaining generalized social phobia and 19 healthy control subjects participated in differential aversive conditioning with two neutral faces as conditioned stimuli and an aversive odor as unconditioned stimulus. Subjective and peripheral physiological responses were obtained. Both groups were successfully conditioned as reflected by differential subjective (valence, arousal, subjective unconditioned stimulus expectancy) and peripheral physiological responses (skin conductance, startle response). There was no evidence for an enhanced conditionability in the social phobics; however, they showed an enhanced unconditioned stimulus expectancy, especially for the nonreinforced conditioned stimuli during acquisition, and a delayed extinction of the conditioned skin conductance response as well as a certain dissociation between subjective and physiological responses.The enhanced unconditioned stimulus expectancy during acquisition and the overall elevated subjective arousal suggest that, under threat, subjects with generalized social phobia may be more prone to associate neutral social cues and an aversive outcome. Furthermore, delayed extinction of the conditioned response seems to contribute to the etiology and maintenance of generalized social phobia.
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GSAD patients exhibit attentional biases for threatening social information and exaggerated affective responses to aversive social cues.
“For example, laboratory studies have shown that GSAD patients exhibit attentional biases for threatening social information (Foa et al, 2000;Mogg et al, 2004), and exaggerated affective responses to aversive social cues (Hermann et al, 2002;Roelofs et al, 2009).”
From Oxytocin modulation of amygdala functional connectivity to fearful faces in generalized social anxiety disorder (2015) · cites this paper as Hermann et al, 2002
Cites
Fears, phobias, and preparedness: toward an evolved module of fear and fear learning
Öhman, A., & Mineka, S. (2001) · Psychological Review · doi:10.1037/0033-295x.108.3.483 · Cited by 3,147 · cited 1× · see citing works
“Due to their evolutionary importance for species survival, certain stimuli, such as snakes or angry faces, appear to be predisposed to superior conditioning as reflected primarily by a heightened resistance to extinction (Öhman and Mineka 2001).”
BackgroundEmotion, attention, and the startle reflex
Lang, P. J., Bradley, M. M., & Cuthbert, B. N. (1990) · Psychological Review · doi:10.1037/0033-295x.97.3.377 · Cited by 2,205 · see citing works
Guidelines for Human Electromyographic Research
Fridlund, A. J., & Cacioppo, J. T. (1986) · Psychophysiology · doi:10.1111/j.1469-8986.1986.tb00676.x · Cited by 1,737 · see citing works
Publication Recommendations for Electrodermal Measurements
Fowles, D. C., Christie, M. J., Edelberg, R., Grings, W. W., Lykken, D. T., & Venables, P. H. (1981) · Psychophysiology · doi:10.1111/j.1469-8986.1981.tb03024.x · Cited by 1,700 · see citing works
Theoretical Issues in Behavior Therapy
Reiss, S., & Bootzin, R. R. (1985) · Medical Entomology and Zoology · Cited by 1,461 · see citing works
The face in the crowd revisited: A threat advantage with schematic stimuli.
Öhman, A., Lundqvist, D., & Esteves, F. (2001) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.80.3.381 · Cited by 1,366 · see citing works
Modulating emotional responses: effects of a neocortical network on the limbic system
Hariri, A. R., Bookheimer, S. Y., & Mazziotta, J. C. (2000) · NeuroReport · doi:10.1097/00001756-200001170-00009 · Cited by 1,277 · see citing works
Brain systems mediating aversive conditioning: an event-related fMRI study
Büchel, C., Morris, J., Dolan, R. J., & Friston, K. J. (1998) · Neuron · doi:10.1016/s0896-6273(00)80476-6 · Cited by 951 · see citing works
ÖHman, A. (1986) · Psychophysiology · doi:10.1111/j.1469-8986.1986.tb00608.x · Cited by 738 · see citing works
De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder.
Orr, S. P., Metzger, L. J., Lasko, N. B., Macklin, M. L., Peri, T., & Pitman, R. K. (2000) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.109.2.290 · Cited by 653 · see citing works
Impaired auditory recognition of fear and anger following bilateral amygdala lesions
Scott, S. K., Young, A. W., Calder, A. J., Hellawell, D. J., Aggleton, J. P., & Johnsons, M. (1997) · Nature · doi:10.1038/385254a0 · Cited by 523 · see citing works
Electrodermal Activity in Psychological Research
(1973) · Elsevier eBooks · doi:10.1016/b978-0-12-565950-5.x5001-7 · Cited by 514 · see citing works
Phobias: A Handbook of Theory, Research and Treatment
Davey, G. C. L., & Leahy, R. L. (2000) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.14.1.115 · Cited by 463 · see citing works
fMRI reveals amygdala activation to human faces in social phobics
Birbaumer, N., Grodd, W., Diedrich, O., Klose, U., Erb, M., Lotze, M., Schneider, F., Weiss, U., & Flor, H. (1998) · NeuroReport · doi:10.1097/00001756-199804200-00048 · Cited by 390 · see citing works
Self-citationThe effect of worry on cardiovascular response to phobic imagery
Borkovec, T. D., & Hu, S. (1990) · Behaviour Research and Therapy · doi:10.1016/0005-7967(90)90056-o · Cited by 386 · see citing works
Grillon, C., & Morgan, C. A. (1999) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.108.1.134 · Cited by 331 · see citing works
Prokasy, W. F., & Kumpfer, K. L. (1973) · Elsevier eBooks · doi:10.1016/b978-0-12-565950-5.50008-9 · Cited by 305 · see citing works
Affective learning: Awareness and aversion
HAMM, A. O., & VAITL, D. (1996) · Psychophysiology · doi:10.1111/j.1469-8986.1996.tb02366.x · Cited by 282 · see citing works
DAVIS, M., Walker, D. L., & LEE, Y. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb48289.x · Cited by 280 · see citing works
Grillon, C., Morgan, C. A., Davis, M., & Southwick, S. M. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00034-1 · Cited by 263 · see citing works
Fear-potentiated startle in posttraumatic stress disorder
Morgan, C. A., Grillon, C., Southwick, S. M., Davis, M., & Charney, D. S. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00321-s · Cited by 242 · see citing works
Social phobia: An analysis of possible developmental factors.
Stemberger, R. M. T., Turner, S. M., Beidel, D. C., & Calhoun, K. S. (1995) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.104.3.526 · Cited by 237 · see citing works
(1992) · Choice Reviews Online · doi:10.5860/choice.30-0280 · Cited by 222 · see citing works
Schneider, F. W., Weiss, U., Kessler, C., Müller-Gärtner, H.-W., Posse, S., Salloum, J. B., Grodd, W., Himmelmann, F. M., Gäebel, W., & Birbaumer, N. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00269-8 · Cited by 220 · see citing works
Self-citationHow do I appear to others? Social anxiety and processing of the observable self
Mansell, W., & Clark, D. M. (1999) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(98)00148-x · Cited by 219 · see citing works
DIPS Diagnostisches Interview bei psychischen Störungen
Margraf, J., Schneider, S., & Ehlers, A. (1991) · Springer eBooks · doi:10.1007/978-3-662-06603-4 · Cited by 201 · see citing works
Emotional learning, hedonic change, and the startle probe.
Hamm, A. O., Greenwald, M. K., Bradley, M. M., & Lang, P. J. (1993) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.102.3.453 · Cited by 195 · see citing works
Preparedness and phobia: Effects of stimulus content on human visceral conditioning.
Cook, E. W., Hodes, R. L., & Lang, P. (1986) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.95.3.195 · Cited by 192 · see citing works
Fear-relevant selective associations and covariation bias.
Tomarken, A. J., Mineka, S., & Cook, M. C. (1989) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.98.4.381 · Cited by 187 · see citing works
Facial expressions as conditioned stimuli for electrodermal responses: A case of "preparedness"?
Öhman, A., & Dimberg, U. (1978) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.36.11.1251 · Cited by 185 · see citing works
Social phobia: An analysis of possible developmental factors.
Stemberger, R. M. T., Turner, S. M., Beidel, D. C., et al. (1995) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.104.3.526 · Cited by 185 · see citing works
Facial expressions as conditioned stimuli for electrodermal responses: A case of "preparedness"?
�hman, A., & Dimberg, U. (1978) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.36.11.1251 · Cited by 183 · see citing works
Standardized mood induction with happy and sad facial expressions
Schneider, F. W., Gur, R. C., Gur, R. E., & Muenz, L. R. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90044-2 · Cited by 181 · see citing works
Fear-relevant selective associations and covariation bias.
Tomarken, A. J., Mineka, S., & Cook, M. C. (1989) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.98.4.381 · Cited by 180 · see citing works
Psychophysiological differences between subgroups of social phobia
Hofmann, S. G., Newman, M. G., Ehlers, A., & Roth, W. T. (1995) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.104.1.224 · Cited by 169 · see citing works
Psychophysiological differences between subgroups of social phobia.
Hofmann, S. G., Newman, M. G., Ehlers, A., & Roth, W. T. (1995) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.104.1.224 · Cited by 169 · see citing works
Preparedness and phobia: Effects of stimulus content on human visceral conditioning.
Cook, E. W., Hodes, R. L., & Lang, P. J. (1986) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.95.3.195 · Cited by 167 · see citing works
Emotional learning, hedonic change, and the startle probe.
Hamm, A. O., Greenwald, M. K., Bradley, M. M., et al. (1993) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.102.3.453 · Cited by 166 · see citing works
Conditioning and ethological models of anxiety disorders: stress-in-dynamic-context anxiety models.
Mineka, S., & Zinbarg, R. E. (1996) · PubMed · Cited by 154 · see citing works
Manual of psychophysiological methods
Rashbass, C. (1967) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(67)90028-1 · Cited by 137 · see citing works
Microexpressive Facial Actions as a Function of Affective Stimuli: Replication and Extension
Cacioppo, J. T., Bush, L. K., & Tassinary, L. G. (1992) · Personality and Social Psychology Bulletin · doi:10.1177/0146167292185001 · Cited by 126 · see citing works
Perspectives on anxiety, panic, and fear
Hope, D. A., & Dienstbier, R. A. (1996) · University of Nebraska Press eBooks · Cited by 124 · see citing works
Kühnel-Pfetzing, A. (2019) · Springer Reference Medizin · doi:10.1007/978-3-642-54672-3_243-1 · Cited by 120 · see citing works
Depressive personality disorder: clinical implications.
Rosenbaum, J. F., Biederman, J., Pollock, R. A., & Hirshfeld, D. R. (1994) · PubMed · Cited by 112 · see citing works
Emotional imagery in simple and social phobia: Fear versus anxiety.
McNeil, D. W., Vrana, S. R., Melamed, B. G., Cuthbert, B. N., & al, E. (1993) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.102.2.212 · Cited by 110 · see citing works
Pitman, R. K., & Orr, S. P. (1986) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.95.3.208 · Cited by 104 · see citing works
Startle reflex modulation during exposure to pleasant and unpleasant odors
Ehrlichman, H., BROWN, S., Zhu, J., & Warrenburg, S. (1995) · Psychophysiology · doi:10.1111/j.1469-8986.1995.tb03306.x · Cited by 97 · see citing works
Todrank, J., Byrnes, D., Wrzesniewski, A., & Rozin, P. N. (1995) · Learning and Motivation · doi:10.1016/0023-9690(95)90001-2 · Cited by 86 · see citing works
Human blink startle during aversive and nonaversive Pavlovian conditioning.
Lipp, O. V., Sheridan, J. S., & Siddle, D. A. T. (1994) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/0097-7403.20.4.380 · Cited by 74 · see citing works
Psychophysiological and subjective reactions of social phobics and normals to facial stimuli
Merckelbach, H. L. G. J., van Hout, W., van den Hout, M., & Mersch, P. P. A. (1989) · Behaviour Research and Therapy · doi:10.1016/0005-7967(89)90048-x · Cited by 58 · see citing works
Lanzetta, J. T., & Orr, S. P. (1986) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.50.1.190 · Cited by 54 · see citing works
Facial expressions as excitatory and inhibitory stimuli for conditioned autonomic responses
Dimberg, U. (1986) · Biological Psychology · doi:10.1016/0301-0511(86)90019-0 · Cited by 46 · see citing works
Flor, H., Birbaumer, N., Roberts, L. E., Feige, B., Lutzenberger, W., Hermann, C., & Kopp, B. (1996) · Experimental Brain Research · doi:10.1007/bf00227648 · Cited by 44 · see citing works
Self-citationLanzetta, J. T., & Orr, S. P. (1986) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.50.1.190 · Cited by 43 · see citing works
Lipp, O. V., Siddle, D. A. T., & Dall, P. J. (1997) · Psychophysiology · doi:10.1111/j.1469-8986.1997.tb02404.x · Cited by 37 · see citing works
Conditioning and ethological models of social phobia.
Mineka, S., & Zinbarg, R. E. (1995) · Cited by 36 · see citing works
Diagnostic utility of autonomic measures for major depressive disorders
Dawson, M. E., Schell, A. M., Braaten, J. R., & Catania, J. J. (1985) · Psychiatry Research · doi:10.1016/0165-1781(85)90063-0 · Cited by 29 · see citing works
Facial reactions to facial expressions in subjects high and low in public speaking fear
Dimberg, U., & Christmanson, L. (1991) · Scandinavian Journal of Psychology · doi:10.1111/j.1467-9450.1991.tb00875.x · Cited by 28 · see citing works
Turner, S. M., Beidel, D. C., & Wolff, P. L. (1994) · Behaviour Research and Therapy · doi:10.1016/0005-7967(94)90012-4 · Cited by 22 · see citing works
Clark, B. M., Siddle, D. A. T., & Bond, N. W. (1992) · Biological Psychology · doi:10.1016/0301-0511(92)90033-q · Cited by 18 · see citing works
Diagnostik der Sozialen Phobie
Stangier, U., & Heidenreich, T. (2009) · Verhaltenstherapie · doi:10.1159/000259016 · Cited by 11 · see citing works
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Classical fear-conditioning in the anxiety disorders: a meta-analysis
Lissek, S., Powers, A. S., McClure, E. B., Phelps, E. A., Woldehawariat, G., Grillon, C., & Pine, D. S. (2005) · Behaviour Research and Therapy · doi:10.1016/j.brat.2004.10.007 · Cited by 1,034 · see citing works
Lonsdorf, T. B., Menz, M. M., Andreatta, M., Fullana, M. A., Golkar, A., Haaker, J., Heitland, I., Hermann, A., Kuhn, M., Kruse, O., et al. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.02.026 · Cited by 837 · see citing works
Duits, P., Cath, D. C., Lissek, S., Hox, J. J., Hamm, A. O., Engelhard, I. M., van den Hout, M. A., & Baas, J. M. P. (2015) · Depression and Anxiety · doi:10.1002/da.22353 · Cited by 726 · see citing works
From Pavlov to PTSD: The extinction of conditioned fear in rodents, humans, and anxiety disorders
VanElzakker, M. B., Kathryn Dahlgren, M., Caroline Davis, F., Dubois, S., & Shin, L. M. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.11.014 · Cited by 482 · see citing works
Mineka, S., & Oehlberg, K. A. (2008) · Acta Psychologica · doi:10.1016/j.actpsy.2007.11.007 · Cited by 406 · see citing works
Neurobiology of fear and specific phobias
Garcia, R. (2017) · Learning & Memory · doi:10.1101/lm.044115.116 · Cited by 239 · see citing works
Dillon, D. G., Rosso, I. M., Pechtel, P., Killgore, W. D. S., Rauch, S. L., & Pizzagalli, D. A. (2014) · Depression and Anxiety · doi:10.1002/da.22202 · Cited by 209 · see citing works
The Body and the Brain: Measuring Skin Conductance Responses to Understand the Emotional Experience
Christopoulos, G. I., Uy, M. A., & Yap, W. (2019) · Organizational Research Methods · doi:10.1177/1094428116681073 · Cited by 204 · see citing works
Fear conditioning in panic disorder: Enhanced resistance to extinction
Michael, T., Blechert, J., Vriends, N., Margraf, J., & Wilhelm, F. H. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.3.612 · Cited by 210 · see citing works
Fearful Imagery in Social Phobia: Generalization, Comorbidity, and Physiological Reactivity
McTeague, L. M., Lang, P. J., Laplante, M.-C., Cuthbert, B. N., Strauss, C. C., & Bradley, M. M. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.023 · Cited by 169 · see citing works
Elevated Fear Conditioning to Socially Relevant Unconditioned Stimuli in Social Anxiety Disorder
Lissek, S., Levenson, J., Biggs, A. L., Johnson, L. L., Ameli, R., Pine, D. S., & Grillon, C. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06091513 · Cited by 158 · see citing works
Punishment has a lasting impact on error‐related brain activity
Riesel, A., Weinberg, A., Endraß, T., Kathmann, N., & Hajcak, G. (2011) · Psychophysiology · doi:10.1111/j.1469-8986.2011.01298.x · Cited by 166 · see citing works
Gorka, S. M., Fitzgerald, D. A., Labuschagne, I., Hosanagar, A., Wood, A. G., Nathan, P. J., & Phan, K. L. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2014.168 · Cited by 131 · see citing works
Social fearfulness in the human brain
Miskovic, V., & Schmidt, L. A. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.08.002 · Cited by 126 · see citing works
Augmentation of Extinction and Inhibitory Learning in Anxiety and Trauma-Related Disorders
Lebois, L. A. M., Seligowski, A. V., Wolff, J. D., Hill, S. B., & Ressler, K. J. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095634 · Cited by 93 · see citing works
Individual differences in learning the affective value of others under minimal conditions.
Bliss-Moreau, E., Barrett, L. F., & Wright, C. I. (2008) · Emotion · doi:10.1037/1528-3542.8.4.479 · Cited by 82 · see citing works
Fear conditioning and stimulus generalization in patients with social anxiety disorder
Ahrens, L. M., Pauli, P., Reif, A., Mühlberger, A., Langs, G., Aalderink, T., & Wieser, M. J. (2016) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2016.10.003 · Cited by 85 · see citing works
Intolerance of uncertainty in eating disorders: an update on the field
Kesby, A., Maguire, S., Brownlow, R., & Grisham, J. R. (2017) · Clinical Psychology Review · doi:10.1016/j.cpr.2017.07.002 · Cited by 83 · see citing works
Barrett, J., & Armony, J. L. (2008) · Psychological Medicine · doi:10.1017/s0033291708003516 · Cited by 84 · see citing works
Conditioned Fear Acquisition and Generalization in Generalized Anxiety Disorder
Tinoco, D., Fullana, M. A., Torrents‐Rodas, D., Bonillo, A., Vervliet, B., Blasco, M. J., Farré, M., & Torrúbia, R. (2014) · Behavior Therapy · doi:10.1016/j.beth.2014.12.004 · Cited by 77 · see citing works
Meulders, A., Meulders, M., Stouten, I., Bie, J. D., & Vlaeyen, J. W. S. (2016) · Journal of Pain · doi:10.1016/j.jpain.2016.10.004 · Cited by 74 · see citing works
Rabinak, C. A., Mori, S., Lyons, M., Milad, M. R., & Phan, K. L. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.09.018 · Cited by 70 · see citing works
Fear conditioning and extinction in anxiety- and depression-prone persons
Dibbets, P., van den Broek, A., & Evers, E. A. T. (2014) · Memory · doi:10.1080/09658211.2014.886704 · Cited by 65 · see citing works
Social anxiety modulates amygdala activation during social conditioning
Pejic, T., Hermann, A., Vaitl, D., & Stark, R. M. (2011) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsr095 · Cited by 61 · see citing works
Rattel, J., Miedl, S., Blechert, J., & Wilhelm, F. (2017) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.12.010 · Cited by 57 · see citing works
From avoidance to approach: The influence of threat-of-shock on reward-based decision making
Bublatzky, F., Alpers, G. W., & Pittig, A. (2017) · Behaviour Research and Therapy · doi:10.1016/j.brat.2017.01.003 · Cited by 59 · see citing works
Siegmund, A., Langnaese, K., & Wotjak, C. T. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.07.007 · Cited by 57 · see citing works
Jens Blechert, A., Lajtman, M., Michael, T., Margraf, J., & Wilhelm, F. H. (2006) · PubMed · doi:10.5451/unibas-ep9417 · Cited by 50 · see citing works
Heterogeneity of the Anxiety-Related Attention Bias: A Review and Working Model for Future Research
Dennis‐Tiwary, T. A., Roy, A. K., Denefrio, S., & Myruski, S. (2019) · Clinical Psychological Science · doi:10.1177/2167702619838474 · Cited by 48 · see citing works
Learning biases underlying individual differences in sensitivity to social rejection.
Olsson, A., Carmona, S., Downey, G., Bolger, N. P., & Ochsner, K. N. (2013) · Emotion · doi:10.1037/a0033150 · Cited by 44 · see citing works
Otto, M. W., Moshier, S. J., Kinner, D. G., Simon, N. M., Pollack, M. H., & Orr, S. P. (2014) · Behavior Therapy · doi:10.1016/j.beth.2013.12.012 · Cited by 46 · see citing works
Ryan, K. M., Zimmer‐Gembeck, M. J., Neumann, D. L., & Waters, A. M. (2018) · Behaviour Research and Therapy · doi:10.1016/j.brat.2018.11.009 · Cited by 44 · see citing works
Single-session attention bias modification and error-related brain activity
Nelson, B. D., Jackson, F. L., Amir, N., & Hajcak, G. (2015) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-015-0365-4 · Cited by 45 · see citing works
Neurobiological aspects of social anxiety disorder.
Furmark, T. (2009) · PubMed · Cited by 43 · see citing works
Fear and safety learning in anxiety- and stress-related disorders: An updated meta-analysis
Kausche, F. M., Carsten, H. P., Sobania, K. M., & Riesel, A. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105983 · Cited by 48 · see citing works
Kiko, S., Stevens, S., Mall, A., Steil, R., Bohus, M., & Hermann, C. (2012) · Behaviour Research and Therapy · doi:10.1016/j.brat.2012.06.001 · Cited by 43 · see citing works
Self-citationEnhanced avoidance behavior in social anxiety: Evidence from a probabilistic learning task
Stevens, S., Peters, A., Abraham, A., & Hermann, C. (2013) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2013.07.007 · Cited by 42 · see citing works
Self-citationSchmidt, L. A., Santesso, D. L., Miskovic, V., Mathewson, K. J., McCabe, R. E., Antony, M. M., & Moscovitch, D. A. (2012) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2012.01.011 · Cited by 41 · see citing works
Reappraisal facilitates extinction in healthy and socially anxious individuals
Jens Blechert, A., Wilhelm, F. H., Williams, H., Braams, B. R., Jou, J., & Gross, J. J. (2014) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2014.10.001 · Cited by 39 · see citing works
Men Scare Me More: Gender Differences in Social Fear Conditioning in Virtual Reality
Reichenberger, J., Pfaller, M. A., Forster, D., Gerczuk, J., Shiban, Y., & Mühlberger, A. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.01617 · Cited by 38 · see citing works
Wake, S. J., Morriss, J., Johnstone, T., van Reekum, C. M., & Dodd, H. F. (2021) · Behaviour Research and Therapy · doi:10.1016/j.brat.2021.103818 · Cited by 33 · see citing works
The influence of state anxiety on the acquisition and extinction of fear
Vriends, N., Michael, T., Jens Blechert, A., Meyer, A. H., Margraf, J., & Wilhelm, F. H. (2010) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2010.09.001 · Cited by 38 · see citing works
The Developmental Psychopathology of Social Anxiety and Phobia in Adolescents
Wong, Q. J. J., & Rapee, R. M. (2015) · Springer eBooks · doi:10.1007/978-3-319-16703-9_2 · Cited by 36 · see citing works
Impaired visuocortical discrimination learning of socially conditioned stimuli in social anxiety
Ahrens, L. M., Mühlberger, A., Pauli, P., & Wieser, M. J. (2014) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsu140 · Cited by 35 · see citing works
Is the chronic fatigue syndrome an exercise phobia? A case control study
Gallagher, A. M., Coldrick, A. R., Hedge, B., Weir, W. R. C., & White, P. D. (2005) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2005.02.002 · Cited by 35 · see citing works
Lieberman, L., Gorka, S. M., Sarapas, C., & Shankman, S. A. (2016) · Cognition and Emotion · doi:10.1080/02699931.2015.1067189 · Cited by 33 · see citing works
Implications of the Research Domain Criteria project for childhood anxiety and its disorders
Lebowitz, E. R., Gee, D. G., Pine, D. S., & Silverman, W. K. (2018) · Clinical Psychology Review · doi:10.1016/j.cpr.2018.01.005 · Cited by 33 · see citing works
Meyer, A. M., & Klein, D. N. (2018) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2018.09.009 · Cited by 33 · see citing works
Measuring the role of conditioning and stimulus generalisation in common fears and worries
Haddad, A. D. M., Xu, M., Raeder, S. M., & Lau, J. Y. F. (2012) · Cognition & Emotion · doi:10.1080/02699931.2012.747428 · Cited by 32 · see citing works
Does pre-exposure inhibit fear context conditioning? A Virtual Reality Study
Tröger, C., Ewald, H., Glotzbach, E., Pauli, P., & Mühlberger, A. (2012) · Journal of neural transmission · doi:10.1007/s00702-011-0757-8 · Cited by 30 · see citing works
The valence of experiences with faces influences generalized preferences
Jones, B. C., DeBruine, L. M., Little, A. C., & Feinberg, D. R. (2007) · Journal of Evolutionary Psychology · doi:10.1556/jep.2007.1001 · Cited by 31 · see citing works
A mechanism-oriented approach to psychopathology: The role of Pavlovian conditioning
Nees, F., Heinrich, A., & Flor, H. (2015) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2015.05.005 · Cited by 31 · see citing works
Self-citationSocial anxiety and cognitive expectancy of aversive outcome in avoidance conditioning
Ly, V., & Karin Roelofs, A. (2009) · Behaviour Research and Therapy · doi:10.1016/j.brat.2009.06.015 · Cited by 30 · see citing works
Heterogeneity in Fear Processing across and within Anxiety, Eating, and Compulsive Disorders
Fyer, A. J., Schneier, F. R., Simpson, H. B., Choo, T. H., Tacopina, S., Kimeldorf, M. B., Steinglass, J. E., Wall, M., & Walsh, B. T. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.03.091 · Cited by 28 · see citing works
A Cognitive Neuroscience Approach to Generalized Anxiety Disorder and Social Phobia
Blair, K. S., & Blair, J. (2012) · Emotion Review · doi:10.1177/1754073911430251 · Cited by 28 · see citing works
Worry and Discrimination of Threat and Safety Cues: An Event-Related Potential Investigation
Grant, D. M., Judah, M. R., White, E. J., & Mills, A. C. (2014) · Behavior Therapy · doi:10.1016/j.beth.2014.09.015 · Cited by 28 · see citing works
The influence of anxiety on electrodermal responses to distractors
Naveteur, J., Stéphanie Buisine, A., & Gruzelier, J. H. (2005) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2004.12.006 · Cited by 26 · see citing works
Estradiol and Women’s Health: Considering the Role of Estradiol as a Marker in Behavioral Medicine
Rieder, J. K., Darabos, K., & Weierich, M. R. (2020) · International Journal of Behavioral Medicine · doi:10.1007/s12529-019-09820-4 · Cited by 24 · see citing works
Rehbein, M., Wessing, I., Zwitserlood, P., Steinberg, C., Eden, A., Dobel, C., & Junghöfer, M. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00155 · Cited by 25 · see citing works
Thinking of attachment figures blocks differential fear conditioning
Toumbelekis, M., Liddell, B. J., & Bryant, R. A. (2018) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsy065 · Cited by 24 · see citing works
Generalization of extinction of a generalization stimulus in fear learning
Wong, A. H. K., & Lovibond, P. F. (2019) · Behaviour Research and Therapy · doi:10.1016/j.brat.2019.103535 · Cited by 24 · see citing works
Tinoco, D., Fullana, M. A., Torrents‐Rodas, D., Bonillo, A., Vervliet, B., Pailhez, G., Farré, M., Andión, Ó., Pérez, V., & Torrúbia, R. (2014) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.1883 · Cited by 23 · see citing works
Low perceived self-efficacy impedes discriminative fear learning
Raeder, F., Karbach, L., Struwe, H., Margraf, J., & Zlomuzica, A. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.01191 · Cited by 22 · see citing works
Pastor, M. C., Rehbein, M. A., Junghöfer, M., Poy, R., pez, R. L., & Moltó, J. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00336 · Cited by 22 · see citing works
Wiggert, N., Wilhelm, F. H., Boger, S., Georgii, C., Klimesch, W., & Blechert, J. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw128 · Cited by 20 · see citing works
Kuehl, L. K., Deuter, C. E., Hellmann‐Regen, J., Kaczmarczyk, M., Otte, C., & Wingenfeld, K. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109751 · Cited by 20 · see citing works
The Influence of State Anxiety on Fear Discrimination and Extinction in Females
Dibbets, P., & Evers, E. A. T. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.00347 · Cited by 19 · see citing works
Associative learning in flying phobia
Vriends, N., Michael, T., Schindler, B., & Margraf, J. (2011) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2011.11.003 · Cited by 16 · see citing works
Threat and safety reversal learning in social anxiety disorder – an fMRI study
Savage, H. S., Davey, C. G., Fullana, M. A., & Harrison, B. J. (2020) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2020.102321 · Cited by 14 · see citing works
Biases in probabilistic category learning in relation to social anxiety
Abraham, A., & Hermann, C. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01218 · Cited by 12 · see citing works
Self-citationHandy, J. D., Avcu, P., Ko, N., Ortiz, A., Doria, M. J., & Servatius, R. J. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.11.014 · Cited by 14 · see citing works
Overgeneralization of fear, but not avoidance, following acute stress
Lemmens, A., Beckers, T., Dibbets, P., Kang, S., & Smeets, T. (2021) · Biological Psychology · doi:10.1016/j.biopsycho.2021.108151 · Cited by 13 · see citing works
Blair, K. S., Otero, M. C., Teng, C. Y., Geraci, M. F., Lewis, E., Hollon, N. G., Blair, J., Monique Ernst, D., Grillon, C., & Pine, D. S. (2016) · Psychological Medicine · doi:10.1017/s0033291716001537 · Cited by 14 · see citing works
Grös, D. F., Hawk, L. W., & Moscovitch, D. A. (2009) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2009.03.001 · Cited by 14 · see citing works
The Impact of State Anxiety on Fear Inhibition
Liao, B., & Craske, M. G. (2013) · Journal of Experimental Psychopathology · doi:10.5127/jep.026612 · Cited by 15 · see citing works
Wake, S. J., Hedger, N., van Reekum, C. M., & Dodd, H. F. (2024) · PeerJ · doi:10.7717/peerj.17262 · Cited by 15 · see citing works
Klein, Z., Abend, R., Shmuel, S., & Shechner, T. (2022) · Biological Psychology · doi:10.1016/j.biopsycho.2022.108314 · Cited by 12 · see citing works
Alterations of Auditory P50 Suppression in Human Fear Conditioning and Extinction
Kurayama, T., Nakazawa, K., Matsuzawa, D., Yoshida, S., Nanbu, M., Suto, C., & Shimizu, E. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.011 · Cited by 12 · see citing works
Yu, K., Tuerlinckx, F., Vanpaemel, W., & Zaman, J. (2023) · Communications Psychology · doi:10.1038/s44271-023-00005-0 · Cited by 10 · see citing works
The Role of Hormonal and Reproductive Status in the Treatment of Anxiety Disorders in Women.
Tang, S., & Graham, B. M. (2020) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-32-9705-0_26 · Cited by 9 · see citing works
Fung, K., & Alden, L. E. (2020) · Journal of Experimental Psychopathology · doi:10.1177/2043808719888309 · Cited by 10 · see citing works
Evans, T. C., Rodriguez, A. M., & Britton, J. C. (2019) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-019-09725-2
Mauchnik, J., Ebner‐Priemer, U., Bohus, M., & Schmahl, C. G. (2010) · Zeitschrift für Psychologie · doi:10.1027/0044-3409/a000015 · Cited by 10 · see citing works
Fear conditioning and fear generalization in children and adolescents with anxiety disorders
Reinhard, J., Mittermeier, A., Brandstetter, L., Mowat, K., Slyschak, A., Reiter, A. M. F., Gamer, M., & Romanos, M. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-023-02304-7 · Cited by 9 · see citing works
Oxytocin and social learning in socially anxious men and women
Flechsenhar, A., Levine, S. M., Müller, L. E., Herpertz, S. C., & Bertsch, K. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.109930 · Cited by 8 · see citing works
The effects of autonomic arousal on speech production in adults who stutter: A preliminary study
Arenas, R. M., & Zebrowski, T. (2013) · Speech Language and Hearing · doi:10.1179/2050572813y.0000000011 · Cited by 8 · see citing works
Meyer, A. M., Hajcak, G., Hayden, E. P., Sheikh, H. I., Singh, S. M., & Klein, D. N. (2017) · Development and Psychopathology · doi:10.1017/s0954579417000517 · Cited by 8 · see citing works
An Evolutionarily Threat-Relevant Odor Strengthens Human Fear Memory
Taylor, J. E., Lau, H. C., Seymour, B., Nakae, A., Sumioka, H., Kawato, M., & Koizumi, A. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00255 · Cited by 8 · see citing works
Mnemonic discrimination and social anxiety: the role of state anxiety
Ponzini, G. T., & Steinman, S. A. (2020) · Cognition & Emotion · doi:10.1080/02699931.2020.1779039 · Cited by 8 · see citing works
Fricke, S., Seinsche, R. J., Neudert, M. K., Schäfer, A., Zehtner, R. I., Stark, R. M., & Hermann, A. (2023) · Psychological Medicine · doi:10.1017/s0033291723002179 · Cited by 6 · see citing works
Psychoanalytic treatment: A neurobiological view.
Cheniaux, E., Zusman, J. A., de Freitas, S., de Carvalho, L. A. V., & Landeira-Fernández, J. (2011) · Psychology & Neuroscience · doi:10.3922/j.psns.2011.3.015 · Cited by 7 · see citing works
Ișıklı, S., Baran, Z., & Aslan, S. (2019) · Journal of Clinical Psychiatry · doi:10.5505/kpd.2019.43660 · Cited by 7 · see citing works
Hunt, C., Fleig, R., Almy, B., & Lissek, S. (2022) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2022.102539 · Cited by 5 · see citing works
Overgeneralization of conditioned fear in patients with social anxiety disorder
Lee, Y. I., Lee, D., Kim, H., Kim, M. J., Jeong, H., Kim, D., Glotzbach-Schoon, E., & Choi, S. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1415135 · Cited by 8 · see citing works
Grützmann, R., Kathmann, N., & Heinzel, S. (2021) · Psychophysiology · doi:10.1111/psyp.13961 · Cited by 7 · see citing works
Becker, M. P. I., Voegler, R., Peterburs, J., Hofmann, D., Bellebaum, C., & Straube, T. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/821512 · Cited by 4 · see citing works
Lernpsychologische Grundlagen der kognitiven Verhaltenstherapie
Michael, T., & Ehlers, A. (2009) · Springer eBooks · doi:10.1007/978-3-540-79541-4_5 · Cited by 3 · see citing works
Is Fear Extinction Impairment Central to Psychopathology?
Bryant, R. A. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_439 · Cited by 2 · see citing works
Extinction of negative conditioned stimulus valence in human fear conditioning
Hyde, J., Farrell, L. J., & Waters, A. M. (2024) · Behaviour Research and Therapy · doi:10.1016/j.brat.2024.104477 · Cited by 2 · see citing works
Sex Differences in Neural Circuits Underlying Fear Processing
Romero, L. R., Acharya, N., Nabás, J. F., Marin‐Blasco, I., & Andero, R. (2024) · Current topics in behavioral neurosciences · doi:10.1007/7854_2024_543 · Cited by 2 · see citing works
- Authors
- Hermann, C., Ziegler, S., Birbaumer, N., & Flor, H.
- Affiliations
- Heidelberg University (DE)
- University of Padua (IT)
- Corresponding author
- Hermann, Christiane
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2002-08
- Volume
- 52
- Issue
- 4
- Pages
- 328-337
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W1972090415
- Cited by
- 120
- References
- 55
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 7 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 8 · 2019: 9 · 2018: 5 · 2017: 8 · 2016: 8 · 2015: 9 · 2014: 10 · 2013: 6 · 2012: 6
- FWCI
- 1.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System (Università degli Studi di Trento) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- generalized social phobia, aversive conditioning, classical conditioning, conditioned emotional response, extinction, skin conductance, startle response, subjective arousal
- MeSH terms
- Adult, Arousal, Association Learning, Avoidance Learning, Conditioning, Classical, Electromyography, Facial Expression, Galvanic Skin Response, Heart Rate, Humans, Male, Pattern Recognition, Visual, Phobic Disorders, Psychophysiology, Smell, Reflex, Startle
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