The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Vertebrate evolution by interspecific hybridisation – are we polyploid?
Abstract
For the growing fraction of human genes with identified functions there are often homologues known from invertebrates such as Drosophila. A survey of well established gene families from aldolases to zinc finger transcription factors reveals that usually a single invertebrate gene corresponds to up to four equally related vertebrate genes on different chromosomes. This pattern was before widely noticed for the Hox gene clusters but appears to be more general. Genome quadruplication by two rounds of hybridisation is discussed as a simple biological mechanism that could have provided the necessary raw material for the success of vertebrate evolution.
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Citations
Cites
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Cited by
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Self-citation
Metadata
- Authors
- Spring, J.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1997-01-02
- Volume
- 400
- Issue
- 1
- Pages
- 2-8
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2158476734
- Cited by
- 297
- References
- 3
- FWCI
- 34.89
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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