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Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.
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“glutamine has been confirmed to be a major nutrient source for oxidative metabolism in some cancer cell lines10–12”
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
A Flexible System of Enzymatic Analysis
Lowry, O. H., & Passonneau, J. V. (1972) · Elsevier eBooks · doi:10.1016/b978-0-12-457950-7.x5001-3 · Cited by 4,050
Nutrition Needs of Mammalian Cells in Tissue Culture
Eagle, H. (1955) · Science · doi:10.1126/science.122.3168.501 · Cited by 1,619
Patterson, M. S., & Greene, R. C. (1965) · Analytical Chemistry · doi:10.1021/ac60226a017 · Cited by 1,459
Uptake and Metabolism of Plasma Glutamine by the Small Intestine
Windmueller, H. G., & Spaeth, A. E. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)42329-6 · Cited by 791
The Path of Carbon in Photosynthesis. V. Paper Chromatography and Radioautography of the Products1
Benson, A. A., Bassham, J. A., Calvin, M., Goodale, T. C., Haas, V. A., & Stepka, W. (1950) · Journal of the American Chemical Society · doi:10.1021/ja01160a080 · Cited by 479
The Use of Glucose-C14 for the Evaluation of the Pathways of Glucose Metabolism
Katz, J. J., & Wood, H. G. (1960) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64593-4 · Cited by 405
Alp, P. R., Newsholme, E. A., & Zammit, V. A. (1976) · Biochemical Journal · doi:10.1042/bj1540689 · Cited by 404
Uber den Stoffwechsel der Karzinomezellen
Warburg, O. (1924) · Medical Entomology and Zoology · Cited by 401
A new method for the determination of inulin in plasma and urine
Heyrovský, A. (1956) · Clinica Chimica Acta · doi:10.1016/0009-8981(56)90020-1 · Cited by 377
Research works printed but not linked: 8
- Paul, 1965, 1, 239
- Cristofalo, 1970, 2, 95
- Graff, 1965, J. Natl. Cancer Inst., 34, 511
- Noll, 1966, Biochem. Z., 346, 41
- Paul, 1956, Biochem. J., 63, 16p
- Munyon, 1941, J. Gen. Physiol., 25, 689
- Krebs, 1943, Adv. Enzymol., 3, 191
- Warburg, 1924, Biochem. Z., 152, 309
Cited by
Sorted by citations
Items 301–400 of 1,001
Bioenergetics of lung tumors: Alteration of mitochondrial biogenesis and respiratory capacity
Bellancé, N., Bénard, G., Furt, F., Bégueret, H., Smolková, K., Passerieux, E., Delage, J. P., Baste, J., Moreau, P., & Rossignol, R. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2009.08.012 · Cited by 85
Metabolism of glutamine in lymphocytes
Brand, K., Fekl, W. L., Hintzenstern, J. V., Langer, K., Luppa, P. B., & Schoerner, C. (1989) · Metabolism · doi:10.1016/0026-0495(89)90136-4 · Cited by 84
Ozturk, S. S., & Palsson, B. Ø. (1991) · Biotechnology Progress · doi:10.1021/bp00012a001 · Cited by 84
Glutamine‐limited batch hybridoma growth and antibody production: Experiment and model
Dalili, M., Sayles, G. D., & Ollis, D. F. (1990) · Biotechnology and Bioengineering · doi:10.1002/bit.260360110 · Cited by 83
Quantitative in vivo nuclear magnetic resonance studies of hybridoma metabolism
Sharfstein, S. T., Tucker, S. N., Mancuso, A., Blanch, H. W., & Clark, D. S. (1994) · Biotechnology and Bioengineering · doi:10.1002/bit.260431109 · Cited by 83
José, C., Hébert-Chatelain, É., Bellancé, N., Larendra, A., Melser, S., Nouette‐Gaulain, K., & Rossignol, R. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2010.12.002 · Cited by 86
Glutamine and glucose metabolism in rat splenocytes and mesenteric lymph node lymphocytes
Wu, G., Field, C. J., & Marliss, E. B. (1991) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1991.260.1.e141 · Cited by 82
The Warburg effect: molecular aspects and therapeutic possibilities
Ngo, H. G., Tortorella, S. M., Ververis, K., & Karagiannis, T. C. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3764-7 · Cited by 81
Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts
Morán, M., Rivera, H., Sánchez‐Aragó, M., Blázquez, A., Merinero, B., Ugalde, C., Arenas, J., Cuezva, J. M., & Martín, M. A. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.02.001 · Cited by 81
Cultivation of hybridoma cells in continuous cultures: Kinetics of growth and product formation
Ray, N. G., Karkare, S. B., & Runstadler, P. W. (1989) · Biotechnology and Bioengineering · doi:10.1002/bit.260330610 · Cited by 81
Filomeni, G., Desideri, E., Cardaci, S., Graziani, I., Piccirillo, S., Rotilio, G., & Ciriolo, M. R. (2010) · Autophagy · doi:10.4161/auto.6.2.10971 · Cited by 79
Bustos, G., Cruz, P., Lovy, A., & Cárdenas, C. (2017) · Frontiers in Oncology · doi:10.3389/fonc.2017.00199 · Cited by 80
Brand, K., Leibold, W., Luppa, P., Schoerner, C., & Schulz, A. (1986) · Immunobiology · doi:10.1016/s0171-2985(86)80086-9 · Cited by 80
Amo, T., Sato, S., Saiki, S., Wolf, A. M., Toyomizu, M., Gautier, C., Shen, J., Ohta, S., & Hattori, N. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.08.027 · Cited by 83
Lampidis, T. J., Kurtoğlu, M., Maher, J. C., Liu, H., Krishan, A., Sheft, V., Szymański, S., Fokt, I., Rudnicki, W. R., Ginalski, K., et al. (2006) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-006-0207-8 · Cited by 79
Chan, B. S., Endo, S., KANAI, N., & Schuster, V. L. (2002) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00151.2001 · Cited by 79
Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism
Cacace, A., Sboarina, M., Vazeille, T., & Sonveaux, P. (2017) · Oncogene · doi:10.1038/onc.2016.364 · Cited by 76
Glutamine in neoplastic cells: Focus on the expression and roles of glutaminases
Szeliga, M., & Obara-Michlewska, M. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.01.008 · Cited by 76
Eyer, K., Oeggerli, A., & Heinzle, E. (1995) · Biotechnology and Bioengineering · doi:10.1002/bit.260450108 · Cited by 78
M Board, Colquhoun, A., & Newsholme, E. A. (1995) · PubMed · Cited by 78
End products of glucose and glutamine metabolism by cultured cell lines
Lanks, K. W., & Li, P. (1988) · Journal of Cellular Physiology · doi:10.1002/jcp.1041350122 · Cited by 78
Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer
Miyo, M., Konno, M., Nishida, N., Sueda, T., Noguchi, K., Matsui, H., Colvin, H. S., Kawamoto, K., Koseki, J., Haraguchi, N., et al. (2016) · Scientific Reports · doi:10.1038/srep38415 · Cited by 77
A flow‐cytometric analysis of hybridoma growth and monoclonal antibody production
Dalili, M., & Ollis, D. F. (1990) · Biotechnology and Bioengineering · doi:10.1002/bit.260360109 · Cited by 77
Operation of a TCA cycle subnetwork in the mammalian nucleus
Kafkia, E., Andrés‐Pons, A., Ganter, K., Seiler, M., Smith, T. S., Andrejeva, A., Jouhten, P., Pereira, F. M., Franco, C., Kuroshchenkova, A., et al. (2022) · Science Advances · doi:10.1126/sciadv.abq5206 · Cited by 76
Glutamine supplementation in cancer patients receiving chemotherapy: A double-blind randomized study
Bozzetti, F., Biganzoli, L., Gavazzi, C., Cappuzzo, F., Carnaghi, C., Buzzoni, R., Bartolomeo, M. D., & Baietta, E. (1997) · Nutrition · doi:10.1016/s0899-9007(97)83038-9 · Cited by 76
Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR
Portais, J., Voisin, P. J., Merle, M., & Canioni, P. (1996) · Biochimie · doi:10.1016/0300-9084(96)89500-9 · Cited by 76
Hardy, C. M., & Mobbs, K. J. (1999) · Molecular Reproduction and Development · doi:10.1002/(sici)1098-2795(199902)52:2 · Cited by 37
Relationship between hybridoma growth and monoclonal antibody production
Hayter, P. M., Kirkby, N. F., & Spier, R. E. (1992) · Enzyme and Microbial Technology · doi:10.1016/0141-0229(92)90137-d · Cited by 74
SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine–Glycine–One-Carbon Pathways in Cancer
Sniegowski, T., Korać, K., Bhutia, Y. D., & Ganapathy, V. (2021) · Pharmaceuticals · doi:10.3390/ph14030216 · Cited by 73
Inhibition of glutaminolysis in combination with other therapies to improve cancer treatment
Shen, Y., Chen, C., Huang, Y., Evans, E. E., Cheng, C., Chuang, Y.-J., Zhang, C., & Le, A. (2021) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2021.01.006 · Cited by 75
Activation of the TOR Signalling Pathway by Glutamine Regulates Insect Fecundity
Zhai, Y., Sun, Z., Zhang, J., Kang, K., Chen, J., & Zhang, W. (2015) · Scientific Reports · doi:10.1038/srep10694 · Cited by 77
Hayter, P. M., Curling, E. M. A., Gould, M. L., Baines, A. J., Jenkins, N., Salmon, I., Strange, P. G., & Bull, A. T. (1993) · Biotechnology and Bioengineering · doi:10.1002/bit.260420909 · Cited by 73
Glutamine Reduces Heat Shock–Induced Cell Death in Rat Intestinal Epithelial Cells
Chow, A., & Zhang, R. (1998) · Journal of Nutrition · doi:10.1093/jn/128.8.1296 · Cited by 73
Glutamine metabolism in the rat
Lund, P. (1980) · FEBS Letters · doi:10.1016/0014-5793(80)80573-4 · Cited by 73
Tumor Metabolism of Malignant Gliomas
Ru, P., Williams, T. M., Chakravarti, A., & Guo, D. (2013) · Cancers · doi:10.3390/cancers5041469 · Cited by 73
Prasad, A., Khatua, A., Mohanta, Y. K., Saravanan, M., Meena, R., & Ghosh, I. (2022) · Nanoscale · doi:10.1039/d2nr02150a · Cited by 72
The Dipeptide Alanyl‐Glutamine Prevents Intestinal Mucosal Atrophy in Parenterally Fed Rats
Tamada, H., Nezu, R., Imamura, I., Matsuo, Y., Takagi, Y., Kamata, S., & Okada, A. (1992) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607192016002110 · Cited by 72
G protein-coupled receptors and the regulation of autophagy
Wauson, E., Dbouk, H. A., Ghosh, A. B., & Cobb, M. H. (2014) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2014.03.006 · Cited by 71
Lin, T.-C., Chen, Y., Kensicki, E., Li, A. Y. J., Kong, M., Li, Y., Mohney, R. P., Shen, H., Stiles, B. L., Mizushima, N., et al. (2012) · Autophagy · doi:10.4161/auto.21228 · Cited by 71
Fahien, L. A., Kmiotek, E., MacDonald, M. J., Fibich, B., & Mandic, M. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)38026-8 · Cited by 71
MALAISSE-LAGAE, F., Sener, A., García-Morales, P., Valverde, I., & Malaisse, W. J. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34845-2 · Cited by 71
Shen, N., Korm, S., Karantanos, T., Li, D., Zhang, X., Ritou, E., Xu, H., Lam, A., English, J., Zong, W., et al. (2021) · Communications Biology · doi:10.1038/s42003-021-02805-8 · Cited by 72
MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca 2+ and Mn 2+
Kamer, K. J., Sancak, Y., Fomina, Y. Y., Meisel, J. D., Chaudhuri, D., Grabarek, Z., & Mootha, V. K. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1807811115 · Cited by 69
Ishaque, A., & Al‐Rubeai, M. (2002) · APOPTOSIS · doi:10.1023/a:1015343616059 · Cited by 70
Altamirano, C., Cairó, J. J., & Gòdia, F. (2001) · Biotechnology and Bioengineering · doi:10.1002/bit.10096 · Cited by 70
Hiller, G. W., Aeschlimann, A., Clark, D. S., & Blanch, H. W. (1991) · Biotechnology and Bioengineering · doi:10.1002/bit.260380707 · Cited by 70
Cancer depends on fatty acids for ATP production: A possible link between cancer and obesity
Lee, H., Woo, S. M., Jang, H., Kang, M., & Kim, S. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.07.005 · Cited by 71
Charni, S., de Bettignies, G., Rathore, M. G., Aguiló, J. I., van den Elsen, P. J., Haouzi, D., Hipskind, R. A., Enrı́quez, J. A., Sánchez‐Beato, M., Pardo, J., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001250 · Cited by 69
Carbon Source Metabolism and Its Regulation in Cancer Cells
Yin, C., Qie, S., & Sang, N. (2012) · Critical Reviews in Eukaryotic Gene Expression · doi:10.1615/critreveukargeneexpr.v22.i1.20 · Cited by 67
Rahman, A. M. A., Ryczko, M. C., Pawling, J., & Dennis, J. W. (2013) · ACS Chemical Biology · doi:10.1021/cb4004173 · Cited by 75
Oxygen Tolerance and Coupling of Mitochondrial Electron Transport
Campian, J. L., Qian, M., Gao, X., & Eaton, J. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406685200 · Cited by 69
Nahapetian, A. T., Thomas, J. N., & Thilly, W. G. (1986) · Journal of Cell Science · doi:10.1242/jcs.81.1.65 · Cited by 69
Application of Immunohistochemistry in the Pathological Diagnosis of Liver Tumors
Takahashi, Y., Dungubat, E., Kusano, H., GANBAT, D., Tomita, Y., Odgerel, S., & Fukusato, T. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115780 · Cited by 68
The metabolic cooperation between cells in solid cancer tumors
Icard, P., Kafara, P., Steyaert, J., Schwartz, L. H., & Lincet, H. (2014) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2014.06.002 · Cited by 74
Control of the NADPH supply for oxidative stress handling in cancer cells
Moreno‐Sánchez, R., Gallardo‐Pérez, J. C., Rodríguez‐Enríquez, S., Saavedra, E., & Marín‐Hernández, Á. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.07.018 · Cited by 68
Houghton, M. J., Kerimi, A., Tumova, S., Boyle, J. P., & Williamson, G. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.037 · Cited by 68
Glutamine limited fed-batch culture reduces the overflow metabolism of amino acids in myeloma cells
Ljunggren, J., & Häggström, L. (1992) · Cytotechnology · doi:10.1007/bf02540029 · Cited by 68
Biochemical aspects of conceptus–endometrial interactions
Bazer, F. W., & Roberts, R. M. (1983) · Journal of Experimental Zoology · doi:10.1002/jez.1402280220 · Cited by 68
The stability of L-glutamine in total parenteral nutrition solutions
Khan, K., Hardy, G., McElroy, B., & Elia, M. (1991) · Clinical Nutrition · doi:10.1016/0261-5614(91)90038-e · Cited by 68
Quantification of ATP‐producing and consuming processes of Ehrlich ascites tumour cells
Müller, M. R., Siems, W., Buttgereit, F., Dumdey, R., & Rapoport, S. M. (1986) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1986.tb10496.x · Cited by 68
Control of cell metabolism by the epidermal growth factor receptor
Orofiamma, L. A., Vural, D., & Antonescu, C. N. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2022.119359 · Cited by 73
Large‐scale production of red blood cells from stem cells: What are the technical challenges ahead?
Rousseau, G. F., Giarratana, M., & Douay, L. (2013) · Biotechnology Journal · doi:10.1002/biot.201200368 · Cited by 67
High yields from microcarrier cultures by medium perfusion
Butler, M., Imamura, T., Thomas, J., & Thilly, W. G. (1983) · Journal of Cell Science · doi:10.1242/jcs.61.1.351 · Cited by 67
Hybridoma growth limitations: The roles of energy metabolism and ammonia production
Newland, M., Greenfield, P. F., & Reid, S. (1990) · Cytotechnology · doi:10.1007/bf00365485 · Cited by 67
Rodríguez‐Enríquez, S., Hernández‐Esquivel, L., Marín‐Hernández, Á., Hafidi, M. E., Gallardo‐Pérez, J. C., Hernández‐Reséndiz, I., Rodríguez‐Zavala, J. S., Pacheco-Velázquez, S. C., & Moreno‐Sánchez, R. (2015) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2015.06.010 · Cited by 66
A novel biotinylated degradable polymer for cell-interactive applications
Cannizzaro, S. M., Padera, R. F., Langer, R., Rogers, R. A., Black, F. E., Davies, M. C., Tendler, S. J. B., & Shakesheff, K. M. (1998) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(19980605)58:5 · Cited by 119
Energy metabolism in cultured human fibroblasts during aging in vitro
Goldstein, S., Ballantyne, S. R., Robson, A. L., & Moerman, E. J. (1982) · Journal of Cellular Physiology · doi:10.1002/jcp.1041120316 · Cited by 66
Miller, W. M., Wilke, C. R., & Blanch, H. W. (1988) · Bioprocess and Biosystems Engineering · doi:10.1007/bf00373473 · Cited by 65
Bienen, E. J., Hammadi, E., & Hill, G. C. (1981) · Experimental Parasitology · doi:10.1016/0014-4894(81)90128-4 · Cited by 65
Pachnis, P., Wu, Z., Faubert, B., Tasdogan, A., Gu, W., Shelton, S. D., Solmonson, A., Rao, A. D., Kaushik, A., Rogers, T. J., et al. (2022) · Science Advances · doi:10.1126/sciadv.abn9550 · Cited by 65
Comparative metabolic analysis of lactate for CHO cells in glucose and galactose
Wilkens, C. A., Altamirano, C., & Gerdtzen, Z. P. (2011) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-010-0409-0 · Cited by 64
Hébert-Chatelain, É., José, C., Cortés, N. G., Dupuy, J., Rocher, C., Dachary-Prigent, J., & Letellier, T. (2012) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2012.01.014 · Cited by 63
Glutaminolysis and glycolysis interactions in proliferant cells
Medina, M. Á., Ignacio, N., & Castro, D. (1990) · International Journal of Biochemistry · doi:10.1016/0020-711x(90)90001-j · Cited by 64
The role of mitochondrial electron transport in tumorigenesis and metastasis
Tan, A. S., Baty, J. W., & Berridge, M. V. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.10.016 · Cited by 65
Mitochondrial Metabolism in Major Neurological Diseases
Zhou, Z., Austin, G. L., Young, L. E. A., Johnson, L. A., & Sun, R. C. (2018) · Cells · doi:10.3390/cells7120229 · Cited by 67
Metabolic changes in cancer cells upon suppression of MYC
Ansó, E., Mullen, A. R., Felsher, D. W., Matés, J. M., DeBerardinis, R. J., & Chandel, N. S. (2013) · Cancer & Metabolism · doi:10.1186/2049-3002-1-7 · Cited by 64
Study of early stage non-small-cell lung cancer using Orbitrap-based global serum metabolomics
Klupczyńska, A., Dereziński, P., Garrett, T. J., Rubio, V. Y., Dyszkiewicz, W., Kasprzyk, M., & Kokot, Z. J. (2017) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-017-2347-0 · Cited by 63
Protective effect of glutamine on endothelial cell ATP in oxidant injury
Hinshaw, D. B., & Burger, J. M. (1990) · Journal of Surgical Research · doi:10.1016/0022-4804(90)90123-j · Cited by 63
Profile of energy metabolism in a murine hybridoma: Glucose and glutamine utilization
Petch, D., & Butler, M. (1994) · Journal of Cellular Physiology · doi:10.1002/jcp.1041610110 · Cited by 63
Engström, W., & Zetterberg, A. (1984) · Journal of Cellular Physiology · doi:10.1002/jcp.1041200218 · Cited by 63
Hassell, T., & Butler, M. (1990) · Journal of Cell Science · doi:10.1242/jcs.96.3.501 · Cited by 63
Tenora, L., Alt, J., Dash, R. P., Gadiano, A. J., Novotná, K., Veeravalli, V., Lam, J., Kirkpatrick, Q. R., Lemberg, K. M., Majer, P., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b02009 · Cited by 62
Insulin signaling requires glucose to promote lipid anabolism in adipocytes
Krycer, J. R., Quek, L., Francis, D., Zadoorian, A., Weiss, F. C., Cooke, K. C., Nelson, M. E., Díaz‐Vegas, A., Humphrey, S. J., Scalzo, R. A., et al. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.014907 · Cited by 64
Assay of the Multiple Energy-Producing Pathways of Mammalian Cells
Bochner, B. R., Siri, M., Huang, R. H., Noble, S., Lei, X.-H., Clemons, P. A., & Wagner, B. K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018147 · Cited by 60
Influence of Progressive Tumor Growth on Glutamine Metabolism in Skeletal Muscle and Kidney
Chen, M. K., Espat, N. J., Bland, K. I., Copeland, E. M., & Souba, W. W. (1993) · Annals of Surgery · doi:10.1097/00000658-199306000-00007 · Cited by 62
Transient kinetics of hybridoma growth and monoclonal antibody production in serum‐limited cultures
Dalili, M., & Ollis, D. F. (1989) · Biotechnology and Bioengineering · doi:10.1002/bit.260330807 · Cited by 62
Kinetics of recombinant immunoglobulin production by mammalian cells in continuous culture
Robinson, D. K., & Memmert, K. (1991) · Biotechnology and Bioengineering · doi:10.1002/bit.260380903 · Cited by 62
Glucose metabolic phenotype of pancreatic cancer
Chan, A. K. C., Bruce, J. I. E., & Siriwardena, A. K. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i12.3471 · Cited by 62
Developement of serum-free media in CHO-DG44 cells using a central composite statistical design
Parampalli, A., Eskridge, K. M., Smith, L. A., Meagher, M. M., Mowry, M. C., & Subramanian, A. (2007) · Cytotechnology · doi:10.1007/s10616-007-9074-3 · Cited by 61
FIUME, L., Manerba, M., Vettraino, M., & Stefano, G. D. (2010) · Pharmacology · doi:10.1159/000317519 · Cited by 60
Sidorenko, Y., Wahl, A., Dauner, M., Genzel, Y., & Reichl, U. (2008) · Biotechnology Progress · doi:10.1021/bp0702673 · Cited by 62
Metabolic control of signalling pathways and metabolic auto‐regulation
Lorendeau, D., Christen, S., Rinaldi, G., & Fendt, S. (2015) · Biology of the Cell · doi:10.1111/boc.201500015 · Cited by 60
Cell Sourcing and Culture Conditions for Fibrin-Based Valve Constructs
Williams, C., Johnson, S. L., Robinson, P. S., & Tranquillo, R. T. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.1489 · Cited by 60
A 1H/15N n.m.r. study of nitrogen metabolism in cultured mammalian cells
Street, J. C., Delort, A. M., Braddock, P., & Brindle, K. M. (1993) · Biochemical Journal · doi:10.1042/bj2910485 · Cited by 60
From cancer metabolism to new biomarkers and drug targets
Chiaradonna, F., Moresco, R. M., Airoldi, C., Gaglio, D., Palorini, R., Nicotra, F., Messa, C., & Alberghina, L. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.07.006 · Cited by 61
Botman, D., Tigchelaar, W., & Noorden, C. J. F. V. (2014) · Journal of Histochemistry & Cytochemistry · doi:10.1369/0022155414549071 · Cited by 58
Khan, A. U. H., Rathore, M. G., Allende-Vega, N., Vo, D.-N., Belkhala, S., Orecchioni, S., Talarico, G., Bertolini, F., Cartron, G., Lecellier, C.-H., et al. (2016) · EBioMedicine · doi:10.1016/j.ebiom.2015.11.045 · Cited by 59
c-Myc inactivation by mutant max alters growth and morphology of NCI-H-630 colon cancer cells
Borrè, A., Cultraro, C. M., & Segal, S. (1996) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199610)169:1 · Cited by 10
Lee, S., Zhang, C., & Liu, X. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.606798 · Cited by 58
Follmar, K. E., DeCroos, F. C., Prichard, H. L., Wang, H. T., Erdmann, D., & Olbrich, K. C. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.3525 · Cited by 58
Metadata
- Authors
- Reitzer, L. J., Wice, B. M., & Kennell, D.
- Affiliations
- Washington University in St. Louis (US)
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1979-04
- Volume
- 254
- Issue
- 8
- Pages
- 2669-2676
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1483212110
- Cited by
- 1,240
- References
- 39
- Citations by year
- 2026: 14 · 2025: 19 · 2024: 30 · 2023: 40 · 2022: 24 · 2021: 45 · 2020: 31 · 2019: 28 · 2018: 42 · 2017: 42 · 2016: 38 · 2015: 38 · 2014: 48 · 2013: 36 · 2012: 46
- FWCI
- 12.54
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biological Chemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- American Cancer Society
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Hypoxia, and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Amino Acid Enzymes and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- glutamine, glucose, energy metabolism, HeLa cells, cultured cells, energy sources
- MeSH terms
- Adenosine Diphosphate, Adenosine Triphosphate, Citric Acid Cycle, Fructose, Galactose, Glucose, Glutamine, HeLa Cells, Humans, Kinetics, Lactates, Pentoses
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