The Biology of Aging
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Muscle mass decreases with age, and strength and power decrease as well; after age 30, the rate of muscle mass decline is approximately 3-8% per decade, and it is even more rapid after age 60.
“Muscle mass decreases with age, and strength and power decrease as well. After age 30, the rate of mass muscle decline is ~3–8% per decade, and it is even more rapid after age 60. 49 , 50”
From Exercise for sarcopenia in older people: A systematic review and network meta‐analysis (2023) · cites this paper as [49]
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Self-citation11 The Etiology and Reversibility of Muscle Dysfunction in the Aged
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Lack of Exercise Is a Major Cause of Chronic Diseases
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Exercise Promotes Healthy Aging of Skeletal Muscle
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Exercise for sarcopenia in older people: A systematic review and network meta‐analysis
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Calorie Restriction and Aging in Humans
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Lifetime sedentary living accelerates some aspects of secondary aging
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Power Versus Sarcopenia: Associations with Functionality and Physical Performance Measures
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- Authors
- Holloszy, J. O.
- Affiliations
- Washington University in St. Louis (US)
- Corresponding author
- Holloszy, John O.
- Venue
- Mayo Clinic Proceedings
- Publisher
- Elsevier BV
- Published
- 2000-01
- Volume
- 75
- Issue
- 1
- Pages
- S3-S9
- ISSN
- 0025-6196 (ISSN-L)
- OpenAlex
- W4322697353
- Cited by
- 136
- References
- 16
- Citations by year
- 2026: 9 · 2025: 21 · 2024: 15 · 2023: 15 · 2022: 15 · 2021: 8 · 2020: 7 · 2019: 6 · 2018: 7 · 2016: 6 · 2015: 4 · 2014: 3 · 2013: 1 · 2012: 4
- FWCI
- 0.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mayo Clinic Proceedings (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Keywords
- aging, longevity, secondary aging, disease development, successful aging, functional capacity, survival curves, diet, physical activity, hormone replacement therapy
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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