Cited by 15,525Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension PharmacologyHemoglobin structure and function

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Nitric oxide: physiology, pathophysiology, and pharmacology.

Moncada, S, Palmer, R M, Higgs, E A·1991·Pharmacological Reviews

DOI 10.1016/s0031-6997(25)06663-3

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Self-citation
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Weiss, G., Goossen, B., Doppler, W., Fuchs, D., Pantopoulos, K., Werner‐Felmayer, G., Wachter, H., & Hentze, M. W. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06039.x · Cited by 389
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Self-citation
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Wu, K. K., & Thiagarajan, P. (1996) · Annual Review of Medicine · doi:10.1146/annurev.med.47.1.315 · Cited by 384
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Ujiié, H., Tachi, H., Hiramatsu, O., Hazel, A. L., Matsumoto, T., Ogasawara, Y., Nakajima, H., Hori, T., Takakura, K., & Kajiya, F. (1999) · Neurosurgery · doi:10.1097/00006123-199907000-00028 · Cited by 381
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Iverson, N. M., Barone, P. W., Shandell, M. A., Trudel, L. J., Şen, S., Şen, F., Ivanov, V., Atolia, E., Farias, E., McNicholas, T. P., et al. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2013.222 · Cited by 381
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Hall, C. N., & Garthwaite, J. (2009) · Nitric Oxide · doi:10.1016/j.niox.2009.07.002 · Cited by 378
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Self-citation
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Shah, A. M., Spurgeon, H. A., Sollott, S. J., Talo, A., & Lakatta, E. G. (1994) · Circulation Research · doi:10.1161/01.res.74.5.970 · Cited by 377
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Allison, A. C., Cacabelos, R., Lombardi, V. R. M., Álvarez, X. A., & Vigo, C. (2001) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(01)00192-0 · Cited by 376
Thiol-based redox switches in eukaryotic proteins
Brandes, N., Schmitt, S., & Jakob, U. (2009) · Antioxidants & Redox Signaling · doi:10.1089/ars.2008.2285 · Cited by 373
Cellular mechanisms regulating human melanogenesis
Park, H., Kosmadaki, M., Yaar, M., & Gilchrest, B. A. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-8703-8 · Cited by 394
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Lundberg, J. O., Carlström, M., & Weitzberg, E. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.06.007 · Cited by 374
Physical training reduces peripheral markers of inflammation in patients with chronic heart failure
Adamopoulos, S. N. (2001) · European Heart Journal · doi:10.1053/euhj.2000.2285 · Cited by 373
Protein Nitration in Cardiovascular Diseases
Turko, I. V., & Murad, F. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.4.619 · Cited by 378
Role of NO in Flow-Induced Remodeling of the Rabbit Common Carotid Artery
Tronc, F., Wassef, M., Esposito, B., Henrion, D., Glagov, S., & Tedgui, A. (1996) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.16.10.1256 · Cited by 372
EPR characterization of molecular targets for NO in mammalian cells and organelles
Henry, Y. A., Lepoivre, M., Drapier, J., Ducrocq, C., Boucher, J., & Guissani, A. (1993) · The FASEB Journal · doi:10.1096/fasebj.7.12.8397130 · Cited by 367
Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells
Taylor-Robinson, A. W., Liew, F. Y., Severn, A., Xu, D., McSorley, S. J., Garside, P., Padron, J., & PHILLIPS, R. S. (1994) · European Journal of Immunology · doi:10.1002/eji.1830240430 · Cited by 370
Diabetes mellitus, hypertension, and cardiovascular disease: Which role for oxidative stress?
Giugliano, D., Ceriello, A., & Paolisso, G. (1995) · Metabolism · doi:10.1016/0026-0495(95)90167-1 · Cited by 369
Polyphenols, intracellular signalling and inflammation.
Santangelo, C., Varı́, R., Scazzocchio, B., Benedetto, R. D., Filesi, C., & Masella, R. (2007) · PubMed · Cited by 368
Neurobiology and consequences of social isolation stress in animal model—A comprehensive review
Mumtaz, F., Khan, M. I., Zubair, M., & Dehpour, A. R. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.05.086 · Cited by 369
NITRERGIC TRANSMISSION: NITRIC OXIDE AS A MEDIATOR OF NON‐ADRENERGIC, NON‐CHOLINERGIC NEURO‐EFFECTOR TRANSMISSION
Rand, M. J. (1992) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.1992.tb00433.x · Cited by 364
Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans. Assessment by bicoronary sodium nitroprusside infusion.
Paulus, W. J., Vantrimpont, P. J. M. J., & Shah, A. M. (1994) · Circulation · doi:10.1161/01.cir.89.5.2070 · Cited by 367
The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine
Cortese-Krott, M. M., Koning, A. M., Kuhnle, G., Nagy, P., Bianco, C. L., Pasch, A., Wink, D. A., Fukuto, J. M., Jackson, A. A., van Goor, H., et al. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7083 · Cited by 371
Transient nitric oxide synthase neurons in embryonic cerebral cortical plate, sensory ganglia, and olfactory epithelium
Bredt, D. S., & Snyder, S. H. (1994) · Neuron · doi:10.1016/0896-6273(94)90348-4 · Cited by 368
Kinetics of Nitrosation of Thiols by Nitric Oxide in the Presence of Oxygen
Kharitonov, V. G., Sundquist, A. R., & Sharma, V. S. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.47.28158 · Cited by 365
Clinical management of low ovarian response to stimulation for IVF: a systematic review
Tarlatzis, B. C. (2003) · Human Reproduction Update · doi:10.1093/humupd/dmg007 · Cited by 364
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Zweier, J. L., Samouilov, A., & Kuppusamy, P. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(99)00018-3 · Cited by 363
Paradoxical fate and biological action of peroxynitrite on human platelets.
Moro, M. Á., Darley-Usmar, V. M., Goodwin, D. A., Read, N. G., Zamora-Pino, R., Feelisch, M., Radomski, M. W., & Moncada, S. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.14.6702 · Cited by 363
Self-citation
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Nakagawa, T., & Yokozawa, T. (2002) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(02)00169-2 · Cited by 362
The Endothelial Nitric-oxide Synthase-Caveolin Regulatory Cycle
Féron, O., Saldaña, F., Michel, J. B., & Michel, T. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.6.3125 · Cited by 361
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Authors: Moncada, S., Palmer, R. M., & Higgs, E. A.
Affiliations: Wellcome Trust (GB)
ORCID: Moncada, S
Palmer, R M
Venue: Pharmacological Reviews
Publisher: Elsevier BV
Published: 1991-06
Volume: 43
Issue: 2
Pages: 109-142
ISSN: 0031-6997 (ISSN-L)
DOI: 10.1016/s0031-6997(25)06663-3
OpenAlex: W1929009802
Cited by: 15,525
References: 0
Citations by year: 2026: 60 · 2025: 87 · 2024: 63 · 2023: 121 · 2022: 122 · 2021: 132 · 2020: 169 · 2019: 187 · 2018: 220 · 2017: 250 · 2016: 273 · 2015: 299 · 2014: 394 · 2013: 379 · 2012: 463
FWCI: 354.59
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Pharmacological Reviews (publishedVersion)
PubMed (publishedVersion)
PubMed
Topics: Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Eicosanoids and Hypertension Pharmacology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Hemoglobin structure and function
Keywords: nitric oxide, nitric oxide synthase, soluble guanylate cyclase, cGMP signaling
MeSH terms: Animals, Blood Platelets, Blood Vessels, Nervous System, Nitric Oxide, Rabbits

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