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Nitric oxide: physiology, pathophysiology, and pharmacology.
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In the citing paper
“However, nitrate is the dominating final oxidation product in plasma with concentrations (micromolar) normally at least 2 orders of magnitude higher than nitrite (nanomolar).35”
From Nitrate-Nitrite-Nitric Oxide Pathway: Implications for Anesthesiology and Intensive Care (2010) · cites this paper as [35]
In the citing paper
“A large number of cytokines and hormones have been shown to induce NOX2 expression, including angiotensin II (658, 714, 802), thrombin (725), and TNF-α (275, 964).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [658]
In the citing paper
“Nitric oxide (NO; nitrogen monoxide) and related nitrogen oxides are now known to be critical endogenous regulators of cell and tissue function (1, 2).”
From What Part of NO Don't You Understand? Some Answers to the Cardinal Questions in Nitric Oxide Biology (2010) · cites this paper as [1]
In the citing paper
“However, studies suggest that nitrate and nitrite may act as a substrate for eNOS-mediated NO generation, even when oxygen levels are limited.”
From The effects of dietary nitrate on blood pressure and endothelial function: a review of human intervention studies (2013) · cites this paper as [98]
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A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis
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Metadata
- Authors
- Moncada, S., Palmer, R. M., & Higgs, E. A.
- Affiliations
- Wellcome Trust (GB)
- Venue
- Pharmacological Reviews
- Publisher
- Elsevier BV
- Published
- 1991-06
- Volume
- 43
- Issue
- 2
- Pages
- 109-142
- ISSN
- 0031-6997 (ISSN-L)
- OpenAlex
- W1929009802
- Cited by
- 15,525
- References
- 0
- Citations by year
- 2026: 60 · 2025: 87 · 2024: 63 · 2023: 121 · 2022: 122 · 2021: 132 · 2020: 169 · 2019: 187 · 2018: 220 · 2017: 250 · 2016: 273 · 2015: 299 · 2014: 394 · 2013: 379 · 2012: 463
- FWCI
- 354.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacological Reviews (publishedVersion)
- PubMed (publishedVersion)
- PubMed
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Eicosanoids and Hypertension Pharmacology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Hemoglobin structure and function
- Keywords
- nitric oxide, nitric oxide synthase, soluble guanylate cyclase, cGMP signaling
- MeSH terms
- Animals, Blood Platelets, Blood Vessels, Nervous System, Nitric Oxide, Rabbits
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