Ecdysone receptors and their biological actions

The nuclear receptor superfamily: the second decade

Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90199-x · Cited by 6,964

Comprehensive insect physiology, biochemistry and pharmacology

(1985) · Journal of Insect Physiology · doi:10.1016/0022-1910(85)90117-9 · Cited by 4,819

Molecular basis of agonism and antagonism in the oestrogen receptor

Brzozowski, A. M., Pike, A. C. W., Dauter, Z., Hubbard, R. E., Bonn, T., Engström, O., Öhman, L., Greene, G. L., Gustafsson, J.-Å., & Carlquist, M. (1997) · Nature · doi:10.1038/39645 · Cited by 3,355

The RXR heterodimers and orphan receptors

Mangelsdorf, D. J., & Evans, R. M. (1995) · Cell · doi:10.1016/0092-8674(95)90200-7 · Cited by 3,165

The development of Drosophila melanogaster

Ingham, P. W. (1994) · Trends in Genetics · doi:10.1016/0168-9525(90)90017-z · Cited by 3,150

DEVELOPMENT IN DROSOPHILA MELANOGASTER

Li, J.-C. (1927) · Genetics · doi:10.1093/genetics/12.2.198 · Cited by 2,878

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Hörlein, A., Näär, A. M., Heinzel, T., Torchia, J., Gloss, B. R., Kurokawa, R., Ryan, A. K., Kamei, Y., Söderström, M., Glass, C. K., et al. (1995) · Nature · doi:10.1038/377397a0 · Cited by 2,072

Steroid hormone receptors: Many Actors in search of a plot

Beato, M., Herrlich, P. A., & Schütz, G. (1995) · Cell · doi:10.1016/0092-8674(95)90201-5 · Cited by 1,816

Encyclopedia of Reproduction

(2018) · Elsevier eBooks · doi:10.1016/c2015-1-06718-7 · Cited by 1,525

YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO AEDES AEGYPTI. L

Roth, T. F., & Porter, K. R. (1964) · The Journal of Cell Biology · doi:10.1083/jcb.20.2.313 · Cited by 1,320

Regulation of Transcription by a Protein Methyltransferase

Chen, D., Ma, H., Hong, H., Koh, S. S., Huang, S., Schurter, B. T., Aswad, D. W., & Stallcup, M. R. (1999) · Science · doi:10.1126/science.284.5423.2174 · Cited by 1,214

A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

Heinzel, T., Lavinsky, R. M., Mullen, T.-M., Söderström, M., Laherty, C. D., Torchia, J., Yang, W., Brard, G., Ngo, S. D., Davie, J., et al. (1997) · Nature · doi:10.1038/387043a0 · Cited by 1,210

A unified nomenclature system for the nuclear receptor superfamily

(1999) · Cell · doi:10.1016/s0092-8674(00)80726-6 · Cited by 1,208

Structure of the ligand‐binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

Pike, A. C. W., Brzozowski, A. M., Hubbard, R. E., Bonn, T., Thorsell, A., Engström, O., Ljunggren, J., Gustafsson, J., & Carlquist, M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.17.4608 · Cited by 990

A canonical structure for the ligand-binding domain of nuclear receptors

Wurtz, J., Bourguet, W., Renaud, J., Vivat, V., Chambon, P., Moras, D., & Gronemeyer, H. (1996) · Nature Structural Biology · doi:10.1038/nsb0196-87 · Cited by 986

The drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily

Koelle, M. R., Talbot, W. S., Segraves, W. A., Bender, M. T., Cherbas, P. T., & Hogness, D. S. (1991) · Cell · doi:10.1016/0092-8674(91)90572-g · Cited by 966

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes

Yao, T., FORMAN, B. M., Jiang, Z., Cherbas, L., Chen, J.-D., McKeown, M., Cherbas, P. T., & Evans, R. M. (1993) · Nature · doi:10.1038/366476a0 · Cited by 947

Structure and specificity of nuclear receptor–coactivator interactionsPreprint

Darimont, B. D., Wagner, R. L., Apriletti, J. W., Stallcup, M. R., Kushner, P. J., Baxter, J. D., Fletterick, R. J., & Yamamoto, K. R. (1998) · Genes & Development · doi:10.1101/gad.12.21.3343 · Cited by 921

New insecticides with ecdysteroidal and juvenile hormone activity

Dhadialla, T. S., Carlson, G. R., & Le, D. P. (1998) · Annual Review of Entomology · doi:10.1146/annurev.ento.43.1.545 · Cited by 912

Coactivator and corepressor complexes in nuclear receptor function

Xu, L., Glass, C. K., & Rosenfeld, M. G. (1999) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(99)80021-5 · Cited by 909

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

No, D. B., Yao, T., & Evans, R. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.8.3346 · Cited by 847

Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation

Yao, T., Segraves, W. A., Oro, A. E., McKeown, M., & Evans, R. M. (1992) · Cell · doi:10.1016/0092-8674(92)90266-f · Cited by 720

ATP-dependent remodeling and acetylation as regulators of chromatin fluidityPreprint

Kingston, R. E., & Narlikar, G. J. (1999) · Genes & Development · doi:10.1101/gad.13.18.2339 · Cited by 702

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes.

Lavinsky, R. M., Jepsen, K., Heinzel, T., Torchia, J., Mullen, T.-M., Schiff, R., Del-Rio, A. L., Ricote, M., Ngo, S., Gemsch, J., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.2920 · Cited by 660

Temporal control of puffing activity in polytene chromosomes

Ashburner, M., Chihara, C., Meltzer, P., & Richards, G. (1974) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1974.038.01.070 · Cited by 641

Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

Korzus, E., Torchia, J., Rose, D. W., Xu, L., Kurokawa, R., McInerney, E. M., Mullen, T.-M., Glass, C. K., & Rosenfeld, M. G. (1998) · Science · doi:10.1126/science.279.5351.703 · Cited by 632

Cellular and Molecular Actions of Juvenile Hormone I. General Considerations and Premetamorphic Actions

Riddiford, L. M. (1994) · Advances in insect physiology · doi:10.1016/s0065-2806(08)60084-3 · Cited by 610

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activationPreprint

McInerney, E. M., Rose, D. W., Flynn, S. E., Westin, S. K., Mullen, T.-M., Krones, A., Inostroza, J. A., Torchia, J., Nolte, R. T., Assa‐Munt, N., et al. (1998) · Genes & Development · doi:10.1101/gad.12.21.3357 · Cited by 610

Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms

Talbot, W. S., Swyryd, E. A., & Hogness, D. S. (1993) · Cell · doi:10.1016/0092-8674(93)90359-x · Cited by 583

A histone deacetylase corepressor complex regulates the Notch signal transduction pathwayPreprint

Kao, H., Ordentlich, P., Koyano‐Nakagawa, N., Tang, Z., Downes, M., Kintner, C. R., Evans, R. M., & Kadesch, T. R. (1998) · Genes & Development · doi:10.1101/gad.12.15.2269 · Cited by 579

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

Kurokawa, R., Söderström, M., Hörlein, A., Halachmi, S., Brown, M. A., Rosenfeld, M. G., & Glass, C. K. (1995) · Nature · doi:10.1038/377451a0 · Cited by 550

Cellular and Molecular Actions of Juvenile Hormone. II. Roles of Juvenile Hormone in Adult Insects

Wyatt, G. R., & Davey, K. G. (1996) · Advances in insect physiology · doi:10.1016/s0065-2806(08)60030-2 · Cited by 522

Metamorphosis : postembryonic reprogramming of gene expression in amphibian and insect cells

Gilbert, L. I., Tata, J. R., & Atkinson, B. G. (1996) · Cited by 507

Flies on steroids — Drosophila metamorphosis and the mechanisms of steroid hormone action

Thummel, C. S. (1996) · Trends in Genetics · doi:10.1016/0168-9525(96)10032-9 · Cited by 488

The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.Preprint

Segraves, W. A., & Hogness, D. S. (1990) · Genes & Development · doi:10.1101/gad.4.2.204 · Cited by 485

Microarray Analysis of Drosophila Development During Metamorphosis

White, K. P., Rifkin, S. A., Hurban, P., & Hogness, D. S. (1999) · Science · doi:10.1126/science.286.5447.2179 · Cited by 464

The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers.

DiBello, P. R., Withers, D. A., Bayer, C. A., Fristrom, J. W., & Guild, G. M. (1991) · Genetics · doi:10.1093/genetics/129.2.385 · Cited by 447

Induktion von puff-veränderungen in den speicheldrüsenchromosomen von Chironomus tentans durch Ecdyson

Clever, U., & Karlson, P. (1960) · Experimental Cell Research · doi:10.1016/0014-4827(60)90141-5 · Cited by 439

Control of Oocyte Maturation in Sexually MatureDrosophilaFemales

Soller, M., Bownes, M., & Kubli, E. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9210 · Cited by 428

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

Burtis, K. C., Thummel, C. S., Jones, C. W., Karim, F. D., & Hogness, D. S. (1990) · Cell · doi:10.1016/0092-8674(90)90217-3 · Cited by 409

Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor

Oro, A. E., McKeown, M., & Evans, R. M. (1990) · Nature · doi:10.1038/347298a0 · Cited by 406

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.Preprint

Kurokawa, R., Yu, V. C. K., Näär, A. M., Kyakumoto, S., Han, Z., Silverman, S., Rosenfeld, M. G., & Glass, C. K. (1993) · Genes & Development · doi:10.1101/gad.7.7b.1423 · Cited by 366

Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators

Westin, S. K., Kurokawa, R., Nolte, R. T., Wisely, G. B., McInerney, E. M., Rose, D. W., Milburn, M. V., Rosenfeld, M. G., & Glass, C. K. (1998) · Nature · doi:10.1038/26040 · Cited by 338

Ecdysteroid titer during larval-pupal-adult development of the tobacco hornworm, Manduca sexta

Bollenbacher, W. E., Smith, S. L., Goodman, W. G., & Gilbert, L. I. (1981) · General and Comparative Endocrinology · doi:10.1016/0016-6480(81)90005-8 · Cited by 325

Hormone Action at the Cellular Level

Riddiford, L. M. (1985) · Elsevier eBooks · doi:10.1016/b978-0-08-030809-8.50008-3 · Cited by 305

Coordination of Drosophila Metamorphosis by Two Ecdysone-Induced Nuclear Receptors

White, K. P., Hurban, P., Watanabe, T., et al. (1997) · Science · doi:10.1126/science.276.5309.114 · Cited by 296

Structure of the Retinoid X Receptor α DNA Binding Domain: a Helix Required for Homodimeric DNA Binding

Lee, M. S., Kliewer, S. A., Provencal, J., Wright, P. E., & Evans, R. M. (1993) · Science · doi:10.1126/science.8388124 · Cited by 292

FTZ-F1, a Steroid Hormone Receptor-like Protein Implicated in the Activation of fushi tarazu

Lavorgna, G., Ueda, H., Clos, J., & Wu, C. (1991) · Science · doi:10.1126/science.1709303 · Cited by 286

Ecdysone receptor expression in the CNS correlates with stage-specific responses to ecdysteroids during Drosophila and Manduca development

Truman, J. W., Talbot, W. S., Fahrbach, S. E., & Hogness, D. S. (1994) · Development · doi:10.1242/dev.120.1.219 · Cited by 283

Recent Advances in Arthropod Endocrinology

Nation, J. L., Coast, G. M., & Webster, S. G. (1999) · Florida Entomologist · doi:10.2307/3495847 · Cited by 281

Drosophila Ecdysone Receptor Mutations Reveal Functional Differences among Receptor Isoforms

Bender, M., Imam, F. B., Talbot, W. S., Ganetzky, B., & Hogness, D. S. (1997) · Cell · doi:10.1016/s0092-8674(00)80466-3 · Cited by 280

Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila

Buszczak, M., Freeman, M. R., Carlson, J. R., Bender, M. T., Cooley, L., & Segraves, W. A. (1999) · Development · doi:10.1242/dev.126.20.4581 · Cited by 276

Neural reorganization during metamorphosis of the corpora pedunculata in Drosophila melanogaster

Technau, G. M., & Heisenberg, M. (1982) · Nature · doi:10.1038/295405a0 · Cited by 270

Molecular Analysis of the Initiation of Insect Metamorphosis: A Comparative Study of Drosophila Ecdysteroid-Regulated Transcription

Andres, A. J., Fletcher, J. C., Karim, F. D., & Thummel, C. S. (1993) · Developmental Biology · doi:10.1006/dbio.1993.1315 · Cited by 268

An ecdysone response element in the Drosophila hsp27 promoter

Riddihough, G., & Pelham, H. R. B. (1987) · The EMBO Journal · doi:10.1002/j.1460-2075.1987.tb02707.x · Cited by 264

Drosophila EcR-B ecdysone receptor isoforms are required for larval molting and for neuron remodeling during metamorphosis

Schubiger, M., Wade, A. A., Carney, G. E., Truman, J. W., & Bender, M. T. (1998) · Development · doi:10.1242/dev.125.11.2053 · Cited by 263

Spatial and temporal patterns of E74 transcription during Drosophila development

Thummel, C. S., Burtis, K. C., & Hogness, D. S. (1990) · Cell · doi:10.1016/0092-8674(90)90218-4 · Cited by 262

Temporal coordination of regulatory gene expression by the steroid hormone ecdysone.

Karim, F. D., & Thummel, C. S. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05501.x · Cited by 257

Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins

Ma, H., Hong, H., Huang, S.-M., Irvine, R. A., Webb, P., Kushner, P. J., Coetzee, G. A., & Stallcup, M. R. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6164 · Cited by 256

Identification of Ecdysis-Triggering Hormone from an Epitracheal Endocrine System

Žitňan, D., Kingan, T. G., Hermesman, J. L., et al. (1996) · Science · doi:10.1126/science.271.5245.88 · Cited by 248

The Drosophila βFTZ-F1 Orphan Nuclear Receptor Provides Competence for Stage-Specific Responses to the Steroid Hormone Ecdysone

Broadus, J., McCabe, J. R., Endrizzi, B. T., et al. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80305-6 · Cited by 245

Activation of mammalian retinoid X receptors by the insect growth regulator methoprene.

Harmon, M. A., Boehm, M. F., Heyman, R. A., & Mangelsdorf, D. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.13.6157 · Cited by 240

Ecdysone metabolism and distribution during the pupal-adult development of Manduca sexta

Warren, J. T., & Gilbert, L. I. (1986) · Insect Biochemistry · doi:10.1016/0020-1790(86)90080-6 · Cited by 234

Hormonal control of rates of metamorphic development in the tobacco hornworm Manduca sexta

Schwartz, L. M., & Truman, J. W. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90257-9 · Cited by 224

Identification of ecdysone response elements by analysis of the Drosophila Eip28/29 gene.Preprint

Cherbas, L., Lee, K., & Cherbas, P. T. (1991) · Genes & Development · doi:10.1101/gad.5.1.120 · Cited by 224

A molecular mechanism for the stage specificity of the Drosophila prepupal genetic response to ecdysone

Woodard, C. T., Baehrecke, E. H., & Thummel, C. S. (1994) · Cell · doi:10.1016/0092-8674(94)90546-0 · Cited by 223

SMRTER, a Drosophila Nuclear Receptor Coregulator, Reveals that EcR-Mediated Repression Is Critical for Development

Tsai, C., Kao, H., Yao, T., McKeown, M., & Evans, R. M. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80365-2 · Cited by 218

Programmed cell death in the Drosophila CNS is ecdysone-regulated and coupled with a specific ecdysone receptor isoform

Robinow, S., Talbot, W. S., Hogness, D. S., & Truman, J. W. (1993) · Development · doi:10.1242/dev.119.4.1251 · Cited by 216

Proteins that bind to Drosophila chorion cis-regulatory elements: a new C2H2 zinc finger protein and a C2C2 steroid receptor-like component.Preprint

Shea, M. J., King, D. L., Conboy, M. J., Mariani, B. D., & Kafatos, F. C. (1990) · Genes & Development · doi:10.1101/gad.4.7.1128 · Cited by 212

Ecdysone-induced change in cellular commitment of the epidermis of the tobacco hornworm, Manduca sexta, at the initiation of metamorphosis

Riddiford, L. M. (1978) · General and Comparative Endocrinology · doi:10.1016/0016-6480(78)90284-8 · Cited by 211

Estradiol repression of tumor necrosis factor-α transcription requires estrogen receptor activation function-2 and is enhanced by coactivators

An, J., Ribeiro, R. C. J., Webb, P., Gustafsson, J.-Α., Kushner, P. J., Baxter, J. D., & Leitman, D. C. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.15161 · Cited by 203

Juvenile Hormone Prevents Ecdysteroid-Induced Expression of Broad Complex RNAs in the Epidermis of the Tobacco Hornworm,Manduca sexta

Zhou, B., Hiruma, K., Shinoda, T., & Riddiford, L. M. (1998) · Developmental Biology · doi:10.1006/dbio.1998.9059 · Cited by 196

Developmental Profiles and Ecdysteroid Regulation of the mRNAs for Two Ecdysone Receptor Isoforms in the Epidermis and Wings of the Tobacco Hornworm,Manduca sexta

Jindra, M., Malone, F., Hiruma, K., & Riddiford, L. M. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0299 · Cited by 189

Effects of juvenile hormone mimics on larval development and metamorphosis of Drosophila melanogaster

Riddiford, L. M., & Ashburner, M. (1991) · General and Comparative Endocrinology · doi:10.1016/0016-6480(91)90181-5 · Cited by 185

Insect silk glands: their types, development and function, and effects of environmental factors and morphogenetic hormones on them

Sehnal, F., & Akai, H. (1990) · International Journal of Insect Morphology and Embryology · doi:10.1016/0020-7322(90)90022-h · Cited by 183

Steroid Induction of a Peptide Hormone Gene Leads to Orchestration of a Defined Behavioral Sequence

Žitňan, D., Ross, L. S., Z̆itn̆anova, I., Hermesman, J. L., Gill, S. S., & Adams, M. E. (1999) · Neuron · doi:10.1016/s0896-6273(00)80805-3 · Cited by 180

Hormonal control of insect epidermal cell commitment in vitro

Riddiford, L. M. (1976) · Nature · doi:10.1038/259115a0 · Cited by 180

The RXR homolog Ultraspiracle is an essential component of the Drosophila ecdysone receptor

Hall, B. L., & Thummel, C. S. (1998) · Development · doi:10.1242/dev.125.23.4709 · Cited by 179

Cloning of an ecdysone receptor homolog from Manduca sexta and the developmental profile of its mRNA in Wings

Fujiwara, H., Jindra, M., Newitt, R. A., Palli, S. R., Hiruma, K., & Riddiford, L. M. (1995) · Insect Biochemistry and Molecular Biology · doi:10.1016/0965-1748(95)00023-o · Cited by 178

A steroid/thyroid hormone receptor superfamily member inDrosophila melanogasterthat shares extensive sequence similarity with a mammalian homologue

Henrich, V. C., Siiter, T. J., Lubahn, D. B., Maclntyre, A., & Gilbert, L. I. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.14.4143 · Cited by 176

Two signalling pathways specify localised expression of the Broad-Complex in Drosophila eggshell patterning and morphogenesis

Deng, W., & Bownes, M. (1997) · Development · doi:10.1242/dev.124.22.4639 · Cited by 174

Ecdysteroid Regulation and DNA Binding Properties of Drosophila Nuclear Hormone Receptor Superfamily Members

Horner, M. A., Chen, T., & Thummel, C. S. (1995) · Developmental Biology · doi:10.1006/dbio.1995.1097 · Cited by 171

Coordination of larval and prepupal gene expression by the DHR3 orphan receptor during Drosophila metamorphosis

Lam, G., Jiang, C., & Thummel, C. S. (1997) · Development · doi:10.1242/dev.124.9.1757 · Cited by 168

The Drosophila E93 Gene from the 93F Early Puff Displays Stage- and Tissue-Specific Regulation by 20-Hydroxyecdysone

Baehrecke, E. H., & Thummel, C. S. (1995) · Developmental Biology · doi:10.1006/dbio.1995.1262 · Cited by 167

Potential role for a FTZ-F1 steroid receptor superfamily member in the control of Drosophila metamorphosis.

Lavorgna, G., Karim, F. D., Thummel, C. S., & Wu, C. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.7.3004 · Cited by 166

DHR3: a Drosophila steroid receptor homolog.

Koelle, M. R., Segraves, W. A., & Hogness, D. S. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.13.6167 · Cited by 163

Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase

Wong, J., Patterton, D., Imhof, A., Guschin, D. Y., Shi, Y., & Wolffe, A. P. (1998) · The EMBO Journal · doi:10.1093/emboj/17.2.520 · Cited by 162

Actinomycin and Puromycin: Effects on Sequential Gene Activation by Ecdysone

Clever, U. (1964) · Science · doi:10.1126/science.146.3645.794 · Cited by 159

Steroid regulation of neuronal death in the moth nervous system

Truman, J., & Schwartz, L. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-01-00274.1984 · Cited by 156

Drosophila hormone receptor 38: a second partner for Drosophila USP suggests an unexpected role for nuclear receptors of the nerve growth factor-induced protein B type.

Sutherland, J. D., Kozlova, T., Tzertzinis, G., & Kafatos, F. C. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.17.7966 · Cited by 156

Iodine Metabolism and Thyroid-Related Functions in Organisms Lacking Thyroid Follicles: Are Thyroid Hormones also Vitamins?

Eales, J. G. (1997) · Experimental Biology and Medicine · doi:10.3181/00379727-214-44098 · Cited by 156

Retinoic acid X receptor in the diploblast, Tripedalia cystophora

Kostrouch, Z., Kostrouchová, M., Love, W. K., Jannini, E. A., Piatigorsky, J., & Rall, J. E. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.23.13442 · Cited by 153

Ecdysteroid control of cell proliferation during optic lobe neurogenesis in the moth Manduca sexta

Champlin, D. T., & Truman, J. W. (1998) · Development · doi:10.1242/dev.125.2.269 · Cited by 153

Methyl Farnesoate: Crustacean Juvenile Hormone in Search of Functions

Homola, E. M., & Chang, E. S. (1997) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s0305-0491(96)00337-9 · Cited by 150

The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis

Oro, A. E., McKeown, M., & Evans, R. M. (1992) · Development · doi:10.1242/dev.115.2.449 · Cited by 149

The mosquito ultraspiracle homologue, a partner of ecdysteroid receptor heterodimer: cloning and characterization of isoforms expressed during vitellogenesis

Kapitskaya, M. Z., Wang, S.-F., Cress, D. E., Dhadialla, T. S., & Raikhel, A. S. (1996) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(96)03847-6 · Cited by 145

Cloning of crustacean ecdysteroid receptor and retinoid-X receptor gene homologs and elevation of retinoid-X receptor mRNA by retinoic acid

Chung, A. C.-K., Durica, D. S., Clifton, S. W., Roe, B. A., & Hopkins, P. M. (1998) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(98)00056-2 · Cited by 144

Peptide Hormones, Steroid Hormones, and Puffs: Mechanisms and Models in Insect Development

Henrich, V. C., Rybczynski, R., & Gilbert, L. I. (1998) · Vitamins and hormones · doi:10.1016/s0083-6729(08)60934-6 · Cited by 142

Bombyx EcR (BmEcR) and Bombyx USP (BmCF1) combine to form a functional ecdysone receptor

Swevers, L., Cherbas, L., Cherbas, P. T., & Iatrou, K. (1996) · Insect Biochemistry and Molecular Biology · doi:10.1016/0965-1748(95)00097-6 · Cited by 139

Identification and mRNA developmental profiles of two ultraspiracle isoforms in the epidermis and wings of Manduca sexta

Jindra, M., Huang, J., Malone, F., Asahina, M., & Riddiford, L. M. (1997) · Insect Molecular Biology · doi:10.1046/j.1365-2583.1997.00153.x · Cited by 139

An extensive ecdysteroid CoMFA

Dinan, L. N., Hormann, R. E., & Fujimoto, T. T. (1999) · Journal of Computer-Aided Molecular Design · doi:10.1023/a:1008052320014 · Cited by 137

Endocrine Cascade in Insect Metamorphosis

Gilbert, L. I., Rybczynski, R., & Tobe, S. S. (1996) · Elsevier eBooks · doi:10.1016/b978-012283245-1/50004-x · Cited by 135

Puffs and PCR: the in vivo dynamics of early gene expression during ecdysone responses in Drosophila

Huet, F., Ruiz, C., & Richards, G. (1993) · Development · doi:10.1242/dev.118.2.613 · Cited by 135

Sequential gene activation by ecdysone in Drosophila melanogaster: the hierarchical equivalence of early and early late genes

Huet, F., Ruiz, C., & Richards, G. (1995) · Development · doi:10.1242/dev.121.4.1195 · Cited by 134

The RXR ortholog USP suppresses early metamorphic processes in Drosophila in the absence of ecdysteroids

Schubiger, M., & Truman, J. W. (2000) · Development · doi:10.1242/dev.127.6.1151 · Cited by 129

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster,

Ashburner, M., & Richards, G. (1976) · Developmental Biology · doi:10.1016/0012-1606(76)90302-x · Cited by 127

Mosquito ecdysteroid receptor: Analysis of the cDNA and expression during vitellogenesis

Cho, W.-L., Kapitskaya, M. Z., & Raikhel, A. S. (1995) · Insect Biochemistry and Molecular Biology · doi:10.1016/0965-1748(94)00045-j · Cited by 126

Ecdysteroids govern two phases of eye development during metamorphosis of the moth, Manduca sexta

Champlin, D. T., & Truman, J. W. (1998) · Development · doi:10.1242/dev.125.11.2009 · Cited by 125

Remodeling of the insect nervous system

Levine, R. B., Morton, D. B., & Restifo, L. L. (1995) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(95)80083-2 · Cited by 119

The dare gene: steroid hormone production, olfactory behavior, and neural degeneration in Drosophila

Freeman, M. R., Dobritsa, A., Gaines, P., Segraves, W. A., & Carlson, J. R. (1999) · Development · doi:10.1242/dev.126.20.4591 · Cited by 119

Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor-regulated gene expression.

Szapary, D., Huang, Y., & Simons, S. (1999) · Molecular Endocrinology · doi:10.1210/mend.13.12.0384 · Cited by 118

Isolation, regulation, and DNA-binding properties of three Drosophila nuclear hormone receptor superfamily members.

Fisk, G. J., & Thummel, C. S. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.23.10604 · Cited by 118

Molecular analysis of the mode of action of RH-5992, a lepidopteran-specific, non-steroidal ecdysteroid agonist

Retnakaran, A., Hiruma, K., Palli, S. R., & Riddiford, L. M. (1995) · Insect Biochemistry and Molecular Biology · doi:10.1016/0965-1748(94)00037-i · Cited by 114

The Drosophila 78C early late puff contains E78, an ecdysone-inducible gene that encodes a novel member of the nuclear hormone receptor superfamily

Stone, B. L., & Thummel, C. S. (1993) · Cell · doi:10.1016/0092-8674(93)80072-m · Cited by 113

Tissue‐Specific and Stage‐Specific Expression of Two Silkworm Ecdysone Receptor Isoforms

Kamimura, M., Tomita, S., Kiuchi, M., et al. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.t01-1-00786.x · Cited by 110

Expression and Function of the ultraspiracle (usp) Gene during Development of Drosophila melanogaster

Henrich, V. C., Szekely, A. A., Kim, S. J., Brown, N. E., Antoniewski, C., Hayden, M. A., Lepesant, J., & Gilbert, L. I. (1994) · Developmental Biology · doi:10.1006/dbio.1994.1232 · Cited by 109

Structural features critical to the activity of an ecdysone receptor binding site

Antoniewski, C., Laval, M., & Lepesant, J. (1993) · Insect Biochemistry and Molecular Biology · doi:10.1016/0965-1748(93)90088-a · Cited by 109

Activation of a Delayed-Early Gene Encoding MHR3 by the Ecdysone Receptor Heterodimer EcR-B1–USP-1 but Not by EcR-B1–USP-2

Lan, Q., Hiruma, K., Hu, X., Jindra, M., & Riddiford, L. M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.7.4897 · Cited by 107

Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor

Dinan, L. N., Whiting, P., Girault, J., Lafont, R., DHADIALLA, S. T., CRESS, E. D., Mugat, B., Antoniewski, C., & Lepesant, J. (1997) · Biochemical Journal · doi:10.1042/bj3270643 · Cited by 106

Intermittent Expression of BmFTZ-F1, a Member of the Nuclear Hormone Receptor Superfamily during Development of the Silkworm Bombyx mori

Sun, G.-C., Hirose, S., & Ueda, H. (1994) · Developmental Biology · doi:10.1006/dbio.1994.1099 · Cited by 106

The ecdysone receptor and ultraspiracle regulate the timing and progression of ovarian morphogenesis during Drosophila metamorphosis

Hodin, J., & Riddiford, L. M. (1998) · Development Genes and Evolution · doi:10.1007/s004270050186 · Cited by 105

DEVELOPMENTAL GENETICS OF THE 2C-D REGION OF THE DROSOPHILA X CHROMOSOME

Perrimon, N., Engstrom, L., & Mahowald, A. P. (1985) · Genetics · doi:10.1093/genetics/111.1.23 · Cited by 105

Hormonal regulation of epidermal metamorphosis in vitro: Control of expression of a larval-specific cuticle gene

Hiruma, K., Hardie, J., & Riddiford, L. M. (1991) · Developmental Biology · doi:10.1016/0012-1606(91)90429-7 · Cited by 104

Direct Repeats Bind the EcR/USP Receptor and Mediate Ecdysteroid Responses in Drosophila melanogaster

Antoniewski, C., Mugat, B., Delbac, F., & Lepesant, J. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.6.2977 · Cited by 104

Mechanistic Principles in NR Box-Dependent Interaction between Nuclear Hormone Receptors and the Coactivator TIF2

Leers, J., Treuter, E., & Gustafsson, J.-Α. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.10.6001 · Cited by 104

Nuclear Receptor Coactivators

Westin, S. K., Rosenfeld, M. G., & Glass, C. K. (1999) · Advances in pharmacology · doi:10.1016/s1054-3589(08)60110-6 · Cited by 103

Molecular Model Systems in the Lepidoptera

(1995) · Cambridge University Press eBooks · doi:10.1017/cbo9780511529931 · Cited by 103

The Function of the Broad-Complex During Drosophila melanogaster Oogenesis

Tzolovsky, G., Deng, W., Schlitt, T., & Bownes, M. (1999) · Genetics · doi:10.1093/genetics/153.3.1371 · Cited by 103

JUVENILE HORMONE AND THE ADULT DEVELOPMENT OFDROSOPHILA

Postlethwait, J. H. (1974) · Biological Bulletin · doi:10.2307/1540573 · Cited by 102

Juvenile hormone modulates 20-hydroxyecdysone-inducible ecdysone receptor and ultraspiracle gene expression in the tobacco hornworm, Manduca sexta

Hiruma, K., Shinoda, T., Malone, F., et al. (1999) · Development Genes and Evolution · doi:10.1007/s004270050223 · Cited by 99

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster,

Richards, G. (1976) · Developmental Biology · doi:10.1016/0012-1606(76)90303-1 · Cited by 98

High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor

Suhr, S. T., Gil, E. B., Senut, M., & Gage, F. H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.14.7999 · Cited by 98

Seven-up Inhibits Ultraspiracle-Based Signaling Pathways In Vitro and In Vivo

Zelhof, A. C., Yao, T., Chen, J. D., Evans, R. M., & McKeown, M. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.12.6736 · Cited by 98

Molecular Aspects of Juvenile Hormone Action in Insect Metamorphosis

Riddiford, L. M. (1996) · Elsevier eBooks · doi:10.1016/b978-012283245-1/50008-7 · Cited by 98

Iodine induction of metamorphosis in Aurelia

Spangenberg, D. B. (1967) · Journal of Experimental Zoology · doi:10.1002/jez.1401650312 · Cited by 96

E75 expression in mosquito ovary and fat body suggests reiterative use of ecdysone-regulated hierarchies in development and reproduction

Pierceall, W. E., Li, C., Biran, A., et al. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(99)00022-2 · Cited by 92

Genes That Induce Apoptosis: Transcriptional Regulation in Identified, Doomed Neurons of theDrosophilaCNS

Robinow, S., Draizen, T. A., & Truman, J. W. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8696 · Cited by 89

Regulation of the Transcription Factor E75 by 20-Hydroxyecdysone and Juvenile Hormone in the Epidermis of the Tobacco Hornworm,Manduca sexta,during Larval Molting and Metamorphosis

Zhou, B., Hiruma, K., Jindra, M., et al. (1998) · Developmental Biology · doi:10.1006/dbio.1997.8798 · Cited by 89

P-Element Insertion Alleles of Essential Genes on the Third Chromosome of Drosophila melanogaster: Mutations Affecting Embryonic PNS Development

Salzberg, A., Prokopenko, S. N., He, Y., Tsai, P., Pál, M., Maróy, P., Glover, D. M., Deák, P., & Bellen, H. J. (1997) · Genetics · doi:10.1093/genetics/147.4.1723 · Cited by 88

Ecdysone pathway is required for furrow progression in the developing Drosophila eye

Brennan, C. A., Ashburner, M., & Moses, K. (1998) · Development · doi:10.1242/dev.125.14.2653 · Cited by 88

Regulation of the EDG84A Gene by FTZ-F1 during Metamorphosis in Drosophila melanogaster

Murata, T., Kageyama, Y., Hirose, S., & Ueda, H. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.11.6509 · Cited by 86

The pupal cuticle of Drosophila: biphasic synthesis of pupal cuticle proteins in vivo and in vitro in response to 20-hydroxyecdysone.

Doctor, J. S., Fristrom, D., & Fristrom, J. W. (1985) · The Journal of Cell Biology · doi:10.1083/jcb.101.1.189 · Cited by 85

BmCF1, a Bombyx mori RXR-type Receptor Related to the Drosophila ultraspiracle

Tzertzinis, G., Małecki, A., & Kafatos, F. C. (1994) · Journal of Molecular Biology · doi:10.1006/jmbi.1994.1306 · Cited by 84

The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster

Bownes, M. (1994) · BioEssays · doi:10.1002/bies.950161009 · Cited by 84

Cloning and developmental expression of the ecdysone receptor gene from the spruce budworm, choristoneura fumiferana

Kothapalli, R., Palli, S. R., Ladd, T. R., Sohi, S. S., Cress, D. E., Dhadialla, T. S., Tzertzinis, G., & Retnakaran, A. (1995) · Developmental Genetics · doi:10.1002/dvg.1020170405 · Cited by 83

DNA Binding and Transactivation Characteristics of the Mosquito Ecdysone Receptor-Ultraspiracle Complex

Wang, S.-F., Miura, K., Miksicek, R. J., Segraves, W. A., & Raikhel, A. S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.42.27531 · Cited by 81

Molecular Biology of Steroid and Nuclear Hormone Receptors

(1998) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4612-1764-0 · Cited by 79

Characterization of the Dopa Decarboxylase Gene of Manduca sexta and Its Suppression by 20-Hydroxyecdysone

Hiruma, K., Carter, M. S., & Riddiford, L. M. (1995) · Developmental Biology · doi:10.1006/dbio.1995.1137 · Cited by 78

p300 stimulates transcription instigated by ligand‐bound thyroid hormone receptor at a step subsequent to chromatin disruption

Li, Q., Imhof, A., Collingwood, T. N., Urnov, F. D., & Wolffe, A. P. (1999) · The EMBO Journal · doi:10.1093/emboj/18.20.5634 · Cited by 78

High level transactivation by the ecdysone receptor complex at the core recognition motif

Vögtli, M., Elke, C., Imhof, M. O., & Lezzi, M. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.10.2407 · Cited by 76

The Ecdysone Response Enhancer of the Fbp1 Gene of Drosophila melanogaster Is a Direct Target for the EcR/USP Nuclear Receptor

Antoniewski, C., Laval, M., Dahan, A., & Lepesant, J. A. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.7.4465 · Cited by 75

Action of Different Ecdysteroids on the Regulation of mRNAs for the Ecdysone Receptor, MHR3, Dopa Decarboxylase, and a Larval Cuticle Protein in the Larval Epidermis of the Tobacco Hornworm,Manduca sexta

Hiruma, K., Böcking, D., Lafont, R., & Riddiford, L. M. (1997) · General and Comparative Endocrinology · doi:10.1006/gcen.1997.6901 · Cited by 74

Building Transcriptional Regulatory Complexes: Signals and SurfacesPreprint

Yamamoto, K. R., Darimont, B. D., WAGNER, R. L., & Iñiguez-Lluhı́, J. A. (1998) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1998.63.587 · Cited by 73

Tissue-specific ecdysone responses: regulation of the Drosophila genes Eip28/29 and Eip40 during larval development

Andres, A. J., & Cherbas, P. T. (1992) · Development · doi:10.1242/dev.116.4.865 · Cited by 73

Tissue-Specific Patterns and Steady-State Concentrations of Ecdysteroid Receptor and Retinoid-X-Receptor mRNA during the Molt Cycle of the Fiddler Crab,Uca pugilator

Chung, A. C.-K., Durica, D. S., & Hopkins, P. M. (1998) · General and Comparative Endocrinology · doi:10.1006/gcen.1997.7046 · Cited by 72

Ecdysteroid receptor and ultraspiracle from Chironomus tentans (Insecta) are phosphoproteins and are regulated differently by molting hormone

Rauch, P. J. G., Grebe, M., Elke, C., Spindler, K., & Spindler‐Barth, M. (1998) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(98)00026-5 · Cited by 71

Alterations in ultraspiracle (USP) content and phosphorylation state accompany feedback regulation of ecdysone synthesis in the insect prothoracic gland

Song, Q., & Gilbert, L. I. (1998) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(98)00075-7 · Cited by 71

Structure of the gene, an ecdysone-inducible gene from Drosophila

Cherbas, L., Schulz, R. A., Koehler, M., Savakis, C., & Cherbas, P. T. (1986) · Journal of Molecular Biology · doi:10.1016/0022-2836(86)90492-4 · Cited by 70

Formation of scale spacing patterns in a moth wing

Nardi, J. B., & Magee-Adams, S. M. (1986) · Developmental Biology · doi:10.1016/0012-1606(86)90131-4 · Cited by 70

The fork head product directly specifies the tissue‐specific hormone responsiveness of the Drosophila Sgs‐4 gene.

Lehmann, M., & Korge, G. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00863.x · Cited by 70

The sequence of Locusta RXR, homologous to Drosophila Ultraspiracle, and its evolutionary implications

Hayward, D. C., Bastiani, M. J., Trueman, J. W. H., Truman, J. W., Riddiford, L. M., & Ball, E. E. (1999) · Development Genes and Evolution · doi:10.1007/s004270050290 · Cited by 70

Steroid and nuclear receptors Villefranche‐sur‐Mer, France, May 25–27, 1999

Croce, L. D., Okret, S., Kersten, S., Gustafsson, J., Parker, M. G., Wahli, W., & Beato, M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.22.6201 · Cited by 70

Embryonic ecdysteroids of Drosophila melanogaster

Maróy, P., Kaufmann, G., & Dübendorfer, A. (1988) · Journal of Insect Physiology · doi:10.1016/0022-1910(88)90071-6 · Cited by 69

Isolation of a functional ecdysteroid receptor homologue from the ixodid tick Amblyomma americanum (L.)

Guo, X., Harmon, M. A., Laudet, V., Mangelsdorf, D. J., & Palmer, M. J. (1997) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(97)00075-1 · Cited by 69

Cloning of Two Putative Ecdysteroid Receptor Isoforms from Tenebrio Molitor and their Developmental Expression in the Epidermis during Metamorphosis

Mouillet, J., Delbecque, J., Quennedey, B., & Delachambre, J. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00856.x · Cited by 68

Analysis of CpG islands of trophoblast giant cells by restriction landmark genomic scanning

Ohgane, J., Aikawa, J.-I., Ogura, A., Hattori, N., Ogawa, T., & Shiota, K. (1998) · Developmental Genetics · doi:10.1002/(sici)1520-6408(1998)22:2 · Cited by 67

The DHR78 Nuclear Receptor Is Required for Ecdysteroid Signaling during the Onset of Drosophila Metamorphosis

Fisk, G. J., & Thummel, C. S. (1998) · Cell · doi:10.1016/s0092-8674(00)81184-8 · Cited by 65

Isolation of two functional retinoid X receptor subtypes from the Ixodid tick, Amblyomma americanum (L.)

Guo, X., Xu, Q. S., Harmon, M. A., Jin, X., Laudet, V., Mangelsdorf, D. J., & Palmer, M. J. (1998) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(98)00073-2 · Cited by 65

Histone Acetyltransferase Complexes Can Mediate Transcriptional Activation by the Major Glucocorticoid Receptor Activation Domain

Wallberg, A. E., Neely, K. E., Gustafsson, J.-Α., Workman, J. L., Wright, A. P. H., & Grant, P. A. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.5952 · Cited by 64

Molecular cloning of an ecdysone receptor (B1 Isoform) homologue from the silkworm, Bombyx mori, and its mRNA expression during wing disc development

Kamimura, M., Tomita, S., & Fujiwara, H. (1996) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/0305-0491(95)02032-2 · Cited by 63

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster,

Richards, G. (1976) · Developmental Biology · doi:10.1016/0012-1606(76)90304-3 · Cited by 63

Molecular Model Systems in the Lepidoptera

Nardi, J. B. (1995) · Science · doi:10.1126/science.269.5231.1743 · Cited by 61

Period Protein Is Necessary for Circadian Control of Egg Hatching Behavior in the Silkmoth Antheraea pernyi

Šauman, I., Tsai, T., Roca, A. L., et al. (1996) · Neuron · doi:10.1016/s0896-6273(00)80221-4 · Cited by 60

Functional characterization of two Ultraspiracle forms (CtUSP-1 and CtUSP-2) from Chironomus tentans

Vogtli, M. E. (1999) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(99)00068-5 · Cited by 57

Expression of ecdysteroid-regulated genes is reduced specifically in the wing discs of the wing-deficient mutant (fl) of Bombyx mori

Matsuoka, T., & Fujiwara, H. (2000) · Development Genes and Evolution · doi:10.1007/s004270050018 · Cited by 57

Steroid and Neuronal Regulation of Ecdysone Receptor Expression during Metamorphosis of Muscle in the Moth,Manduca sexta

Hegstrom, C. D., Riddiford, L. M., & Truman, J. W. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-05-01786.1998 · Cited by 56

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster

Richards, G. (1978) · Developmental Biology · doi:10.1016/0012-1606(78)90271-3 · Cited by 55

Molecular Characterization of the 71E Late Puff in Reveals a Family of Novel Genes

Wright, L. G., Chen, T., Thummel, C. S., et al. (1996) · Journal of Molecular Biology · doi:10.1006/jmbi.1996.0032 · Cited by 55

The Drosophila Eip78C Gene Is Not Vital But Has a Role in Regulating Chromosome Puffs

Russell, S. R. H., Heimbeck, G., Goddard, C. M., Carpenter, A. T. C., & Ashburner, M. (1996) · Genetics · doi:10.1093/genetics/144.1.159 · Cited by 55

Cell Culture Approaches to Understanding the Actions of Steroid Hormones on the Insect Nervous System

Levine, R. B., & Weeks, J. C. (2007) · Developmental Neuroscience · doi:10.1159/000111397 · Cited by 54

The Ecdysone Regulatory Cascades in Drosophila

Richards, G. (1997) · Advances in developmental biology · doi:10.1016/s1566-3116(08)60036-5 · Cited by 53

Cloning and characterization of LcEcR: A functional ecdysone receptor from the sheep blowfly Lucilia cuprina

Hannan, G. N., & Hill, R. J. (1997) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(97)00019-2 · Cited by 53

A role for Ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation

Zelhof, A. C., Ghbeish, N., Tsai, C., Evans, R. M., & McKeown, M. (1997) · Development · doi:10.1242/dev.124.13.2499 · Cited by 52

Ecdysteroids: a new generic term

Goodwin, T. W., Horn, D. H. S., Karlson, P., Koolman, J., Nakanishi, K., Robbins, W. E., SIDDALL, J. B., & TAKEMOTO, T. (1978) · Nature · doi:10.1038/272122a0 · Cited by 52

Studies on two ecdysone receptor isoforms of the spruce budworm, Choristoneura fumiferana

Perera, S. C., Ladd, T. R., Dhadialla, T. S., Krell, P. J., Sohi, S. S., Retnakaran, A., & Palli, S. R. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(99)00058-1 · Cited by 52

Ecdysone-Regulated Chromosome Puffing in Drosophila melanogaster

Russell, S. R. H., & Ashburner, M. (1996) · Elsevier eBooks · doi:10.1016/b978-012283245-1/50005-1 · Cited by 51

Transcriptional regulation: SWItching circuitry

Wade, P. A., & Wolffe, A. P. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80134-1 · Cited by 50

The moulting hormone ecdysone is able to recognize target elements composed of direct repeats

D’Avino, P. P., Crispi, S., Cherbas, L., Cherbas, P. T., & Furia, M. (1995) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(95)03584-t · Cited by 50

Effects of all‐trans retinoic acid on regenerating limbs of the fiddler crab,Uca pugilator

Hopkins, P. M., & Durica, D. S. (1995) · Journal of Experimental Zoology · doi:10.1002/jez.1402720607 · Cited by 49

Autoradiographic identification of ecdysteroid‐binding cells in the nervous system of the moth Manduca sexta

Fahrbach, S. E., & Truman, J. W. (1989) · Journal of Neurobiology · doi:10.1002/neu.480200803 · Cited by 49

The Drosophila Fork Head Factor Directly Controls Larval Salivary Gland-Specific Expression of the Glue Protein Gene Sgs3

Mach, V., Ohno, K., Kokubo, H., & Suzuki, Y. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.12.2387 · Cited by 49

Steroid regulation of excitability in identified insect neurosecretory cells

Hewes, R. S., & Truman, J. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01812.1994 · Cited by 47

Two new regulatory elements controlling the Drosophila Sgs-3 gene are potential ecdysone receptor and fork head binding sites

Lehmann, M., Wattler, F., & Korge, G. (1997) · Mechanisms of Development · doi:10.1016/s0925-4773(96)00644-2 · Cited by 46

An Immunophilin is a Component of the Insect Ecdysone Receptor (EcR) Complex

Song, Q., Alnemri, E. S., Litwack, G., & Gilbert, L. I. (1997) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(97)00080-5 · Cited by 45

Creation of ecdysone receptor chimeras in plants for controlled regulation of gene expression

Martinez, A., Sparks, C., Drayton, P., Thompson, J., Greenland, A., & Jepson, I. (1999) · Molecular and General Genetics MGG · doi:10.1007/s004380050999 · Cited by 45

Expression of ecdysteroid-regulated transcripts in the silk gland of the wax moth, Galleria mellonella

Jindra, M., & Riddiford, L. M. (1996) · Development Genes and Evolution · doi:10.1007/s004270050057 · Cited by 45

Cuticle formation in the embryo of Drosophila melanogaster

Hillman, R., & Lesnik, L. H. (1970) · Journal of Morphology · doi:10.1002/jmor.1051310403 · Cited by 44

Characterization ofEcRandRXRGene Homologs and Receptor Expression During the Molt Cycle in the Crab,Uca pugilator

Durica, D. S., Chung, A. C.-K., & Hopkins, P. M. (1999) · American Zoologist · doi:10.1093/icb/39.4.758 · Cited by 44

Cloning and characterization of an ecdysone receptor cDNA from Locusta migratoria

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