Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

Otto, F., Thornell, A., Crompton, T., Denzel, A., Gilmour, K. C., Rosewell, I. R., Stamp, G., Beddington, R. S. P., Mundlos, S., Olsen, B. R., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80259-7 · Cited by 2,813

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

Luo, G., Ducy, P. F., McKee, M. D., Pinero, G. J., Loyer, E. M., Behringer, R. R., & Karsenty, G. (1997) · Nature · doi:10.1038/386078a0 · Cited by 2,118

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.Preprint

Hogan, B. L. M. (1996) · Genes & Development · doi:10.1101/gad.10.13.1580 · Cited by 1,964

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.Preprint

Kingsley, D. M. (1994) · Genes & Development · doi:10.1101/gad.8.2.133 · Cited by 1,920

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G., & Downing, J. R. (1996) · Cell · doi:10.1016/s0092-8674(00)80986-1 · Cited by 1,856

The Atlas of Mouse Development

Kaufman, M. H. (1992) · Medical Entomology and Zoology · Cited by 1,750

Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia

Mundlos, S., Otto, F., Mundlos, C., Mulliken, J. B., Aylsworth, A. S., Albright, S. G., Lindhout, D., Cole, W. G., Henn, W., Knoll, J. H. M., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80260-3 · Cited by 1,502

Adipogenesis and Obesity: Rounding Out the Big Picture

Spiegelman, B. M., & Flier, J. S. (1996) · Cell · doi:10.1016/s0092-8674(00)81359-8 · Cited by 1,262

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.Preprint

Karaplis, A. C., Luz, A., Glowacki, J., Bronson, R. T., Tybulewicz, V. L. J., Kronenberg, H. M., & Mulligan, R. C. (1994) · Genes & Development · doi:10.1101/gad.8.3.277 · Cited by 1,151

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

Piccolo, S., Sasai, Y., Lu, B., & Robertis, E. M. D. (1996) · Cell · doi:10.1016/s0092-8674(00)80132-4 · Cited by 1,127

Osteoblast role in osteoarthritis pathogenesis

Maruotti, N., Corrado, A., & Cantatore, F. P. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.25969 · Cited by 144

Molecular switching of osteoblastogenesis versus adipogenesis: implications for targeted therapies

Takada, I., Kouzmenko, A., & Kato, S. (2009) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728220902915310 · Cited by 147

RUNX3 Inactivation by Point Mutations and Aberrant DNA Methylation in Bladder Tumors

Kim, W., Kim, E., Jeong, P., Quan, C., Kim, J., Li, Q.-L., Yang, J.-O., Ito, Y., & Bae, S. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1647 · Cited by 143

Both AP-1 and Cbfa1-like factors are required for the induction of interstitial collagenase by parathyroid hormone

Porte, D., Tuckermann, J. P., Becker, M., Baumann, B., Teurich, S., Higgins, T., Owen, M. J., Schorpp‐Kistner, M., & Angel, P. E. (1999) · Oncogene · doi:10.1038/sj.onc.1202333 · Cited by 143

Transforming Growth Factor β2 Inhibits Adipocyte Differentiation Induced by Skeletal Unloading in Rat Bone Marrow Stroma

Ahdjoudj, S., Lasmoles, F., Holy, X., Zérath, E., & Marie, P. J. (2002) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2002.17.4.668 · Cited by 144

Impaired Bone Formation in Transgenic Mice Resulting from Altered Integrin Function in Osteoblasts

Zimmerman, D., Jin, F., Leboy, P., Hardy, S., & Damsky, C. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9633 · Cited by 141

Bone Morphogenetic Protein‐2 Decreases MicroRNA‐30b and MicroRNA‐30c to Promote Vascular Smooth Muscle Cell Calcification

Balderman, J., Lee, H.-Y., Mahoney, C. E., Handy, D. E., White, K., Annis, S., Lebeche, D., Hajjar, R. J., Loscalzo, J., & Leopold, J. A. (2012) · Journal of the American Heart Association · doi:10.1161/jaha.112.003905 · Cited by 142

Ets transcription factors and targets in osteogenesis

Raouf, A., & Seth, A. K. (2000) · Oncogene · doi:10.1038/sj.onc.1204037 · Cited by 143

Patched1 Haploinsufficiency Increases Adult Bone Mass and Modulates Gli3 Repressor Activity

Ohba, S., Kawaguchi, H., Kugimiya, F., Ogasawara, T., Kawamura, N., Saito, T., Ikeda, T., Fujii, K., Miyajima, T., Kuramochi, A., et al. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.03.007 · Cited by 143

Bone marrow and bone: a functional unit

Compston, J. (2002) · Journal of Endocrinology · doi:10.1677/joe.0.1730387 · Cited by 143

Extracellular Matrix-Associated Bone Morphogenetic Proteins Are Essential for Differentiation of Murine Osteoblastic Cellsin Vitro1

Suzawa, M., Takeuchi, Y., Fukumoto, S., Kato, S., Ueno, N., Miyazono, K., Matsumoto, T., & Fujita, T. (1999) · Endocrinology · doi:10.1210/endo.140.5.6704 · Cited by 142

A Feasibility of Useful Cell-Based Therapy by Bone Regeneration with Deciduous Tooth Stem Cells, Dental Pulp Stem Cells, or Bone-Marrow-Derived Mesenchymal Stem Cells for Clinical Study Using Tissue Engineering Technology

Yamada, Y., Nakamura, S., Ito, K., Sugito, T., Yoshimi, R., Nagasaka, T., & Ueda, M. (2010) · Tissue Engineering Part A · doi:10.1089/ten.tea.2009.0732 · Cited by 142

Inflammation in bone physiology and pathology

Adamopoulos, I. E. (2017) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000449 · Cited by 145

Regulation of Runx2 by post-translational modifications in osteoblast differentiation

Gomathi, K., Akshaya, N., Srinaath, N., Moorthi, A., & Selvamurugan, N. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.117389 · Cited by 144

Accelerated Turnover of Metaphyseal Trabecular Bone in Mice Overexpressing Cathepsin K

Kiviranta, R., Morko, J. P., Uusitalo‐Järvinen, H., Aro, H. T., VUORIO, E. I., & Rantakokko, J. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.8.1444 · Cited by 142

Smad-Runx Interactions During Chondrocyte Maturation

Leboy, P. S., Grasso-Knight, G., D’Angelo, M., Volk, S. W., Lian, J. B., Drissi, H., Stein, G. S., & ADAMS, S. L. (2001) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-200100001-00003 · Cited by 142

The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons

Marmigère, F., Montelius, A., Wegner, M., Groner, Y., Reichardt, L. F., & Ernfors, P. (2006) · Nature Neuroscience · doi:10.1038/nn1631 · Cited by 141

Signaling Pathways Involved in Osteogenesis and Their Application for Bone Regenerative Medicine

Hayrapetyan, A., Jansen, J. A., & van den Beucken, J. J. J. P. (2014) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2014.0119 · Cited by 146

cAMP/PKA Regulates Osteogenesis, Adipogenesis and Ratio of RANKL/OPG mRNA Expression in Mesenchymal Stem Cells by Suppressing Leptin

Yang, D.-C., Tsay, H.-J., Lin, S.-Y., Chiou, S., Li, M.-J., Chang, T.-J., & Hung, S. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001540 · Cited by 141

Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation

Phillips‐Cremins, J. E., Gersbach, C. A., Wojtowicz, A. M., & Garcı́a, A. J. (2006) · Journal of Cell Science · doi:10.1242/jcs.02758 · Cited by 141

Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor

Xiao, Z., Thomas, R. F., Hinson, T. K., & Quarles, L. D. (1998) · Gene · doi:10.1016/s0378-1119(98)00227-3 · Cited by 141

Effects of a miR-31, Runx2 , and Satb2 Regulatory Loop on the Osteogenic Differentiation of Bone Mesenchymal Stem Cells

Deng, Y., Wu, S., Zhou, H., Bi, X., Wang, Y., Hu, Y., Gu, P., & Fan, X. (2013) · Stem Cells and Development · doi:10.1089/scd.2012.0686 · Cited by 141

Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration

Benoit, D. S. W., Nuttelman, C. R., Collins, S. D., & Anseth, K. S. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.06.031 · Cited by 140

Mitogen-activated Protein Kinase (MAPK)-regulated Interactions between Osterix and Runx2 Are Critical for the Transcriptional Osteogenic Program

Artigas, N., Martín, C. U., Rodríguez-Carballo, E., Rosa, J. L., & Ventura, F. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.576793 · Cited by 140

miR-181a promotes osteoblastic differentiation through repression of TGF-β signaling molecules

Bhushan, R., Grünhagen, J., Becker, J., Robinson, P. N., Ott, C., & Knaus, P. I. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.12.008 · Cited by 140

The Osteoblast Transcription Factor Runx2 Is Expressed in Mammary Epithelial Cells and Mediates osteopontin Expression

Inman, C. K., & Shore, P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308001200 · Cited by 140

Multiple Cbfa/AML Sites in the Rat Osteocalcin Promoter Are Required for Basal and Vitamin D-Responsive Transcription and Contribute to Chromatin Organization

Javed, A., Gutiérrez, S., Montecino, M. A., van Wijnen, A. J., Stein, J. L., Stein, G. S., & Lian, J. B. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.11.7491 · Cited by 140

Cranial Suture Biology

Lenton, K. A., Nacamuli, R. P., Wan, D. C., Helms, J. A., & Longaker, M. T. (2005) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(05)66009-7 · Cited by 140

Genetic and Transcriptional Control of Bone Formation

Javed, A., Chen, H., & Ghori-Javed, F. Y. (2010) · Oral and Maxillofacial Surgery Clinics of North America · doi:10.1016/j.coms.2010.05.001 · Cited by 143

A role for cadherins in cellular signaling and differentiation

Knudsen, K. A., Frankowski, C., Johnson, K. R., & Wheelock, M. J. (1998) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(1998)72:30/31+ · Cited by 88

Effects of Cyclic Mechanical Stretching on the mRNA Expression of Tendon/Ligament-Related and Osteoblast-Specific Genes in Human Mesenchymal Stem Cells

Chen, Y., Huang, C.-H., Lee, I., Lee, Y.-T., Chen, M., & Young, T. (2008) · Connective Tissue Research · doi:10.1080/03008200701818561 · Cited by 137

Inhibition of Osteoblast-specific Transcription Factor Cbfa1 by the cAMP Pathway in Osteoblastic Cells

Tintut, Y., Parhami, F., Le, V., Karsenty, G., & Demer, L. L. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.41.28875 · Cited by 137

The Leukemic Protein Core Binding Factor β (CBFβ)–Smooth-Muscle Myosin Heavy Chain Sequesters CBFα2 into Cytoskeletal Filaments and Aggregates

Adya, N., Stacy, T., Speck, N. A., & Liu, P. P. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.12.7432 · Cited by 136

HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma

Standal, T., Abildgaard, N., Fagerli, U.-M., Stordal, B., Hjertner, Ø., Borset, M., & Sundan, A. (2007) · Blood · doi:10.1182/blood-2006-07-034884 · Cited by 167

Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways

Sethi, S., Radio, N. M., Kotlarczyk, M. P., Chen, C.-T., Wei, Y., Jockers, R., & Witt‐Enderby, P. A. (2010) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2010.00784.x · Cited by 136

Runx2: of bone and stretch

Ziros, P. G., Basdra, E. K., & Papavassiliou, A. G. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2007.05.024 · Cited by 136

Telomerase Accelerates Osteogenesis of Bone Marrow Stromal Stem Cells by Upregulation of CBFA1, Osterix, and Osteocalcin

Gronthos, S., Chen, S., Wang, C., Robey, P. G., & Shi, S. (2003) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2003.18.4.716 · Cited by 134

Differentiation of preosteoblasts is affected by implant surface microtopographies

Schneider, G. B., Zaharias, R. S., Seabold, D., Keller, J. C., & Stanford, C. M. (2004) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30016 · Cited by 136

Revisiting the Advances in Isolation, Characterization and Secretome of Adipose-Derived Stromal/Stem Cells

Dubey, N. K., Mishra, V. K., Dubey, R., Deng, Y.-H., Tsai, F.-C., & Deng, W. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19082200 · Cited by 141

Osterix enhances proliferation and osteogenic potential of bone marrow stromal cells

Tu, Q., Valverde, P., & Chen, J. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.01.092 · Cited by 135

Hierarchy revealed in the specification of three skeletal fates by Sox9 and Runx2

Eames, B. F., Sharpe, P. T., & Helms, J. A. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.07.006 · Cited by 135

Stem Cell Niche: Microenvironment and Beyond

Zhang, J., & Li, L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r700043200 · Cited by 130

Epigallocatechin-3-gallate Inhibits Osteoclastogenesis by Down-Regulating c-Fos Expression and Suppressing the Nuclear Factor-κB Signal

Lee, J.-H., Hexiu, J., Shim, H., Kim, H., Ha, H., & Lee, Z. H. (2009) · Molecular Pharmacology · doi:10.1124/mol.109.057877 · Cited by 135

Bone-Specific Transcription Factor Runx2 Interacts with the 1α,25-Dihydroxyvitamin D3 Receptor To Up-Regulate Rat Osteocalcin Gene Expression in Osteoblastic Cells

Paredes, R., Arriagada, G., Cruzat, F., Villagra, A., Olate, J., Zaidi, K., van Wijnen, A. J., Lian, J. B., Stein, G. S., Stein, J. L., et al. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.20.8847-8861.2004 · Cited by 135

Submicron Scale‐Structured Hydrophilic Titanium Surfaces Promote Early Osteogenic Gene Response for Cell Adhesion and Cell Differentiation

Klein, M. O., Bijelic, A., Ziebart, T., Koch, F., Kämmerer, P. W., Wieland, M., Konerding, M. A., & Al‐Nawas, B. (2011) · Clinical Implant Dentistry and Related Research · doi:10.1111/j.1708-8208.2011.00339.x · Cited by 134

Wnt signaling inhibits cementoblast differentiation and promotes proliferation

Nemoto, E., 越川, 洋., Kanaya, S., Tsuchiya, M., Tamura, M., Somerman, M. J., & Shimauchi, H. (2009) · Bone · doi:10.1016/j.bone.2008.12.029 · Cited by 136

Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development

Han, J., Ishii, M., Bringas, P., Maas, R. L., Maxson, R. E., & Chai, Y. (2007) · Mechanisms of Development · doi:10.1016/j.mod.2007.06.006 · Cited by 134

Molecular Anatomy of an Intracranial Aneurysm

Peters, D. G., Kassam, A. B., Feingold, E., Heidrich-O’Hare, E., Yonas, H., Ferrell, R. E., & Brufsky, A. (2001) · Stroke · doi:10.1161/01.str.32.4.1036 · Cited by 134

Ablation of the Sam68 RNA Binding Protein Protects Mice from Age-Related Bone Loss

Richard, S., Torabi, N., Franco, G. V., Tremblay, G. A., Chen, T., Vogel, G., Morel, M., Cléroux, P., Forget-Richard, A., Komarova, S., et al. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0010074 · Cited by 133

Polymorphisms in the osteopontin promoter affect its transcriptional activity.

Giacopelli, F., Marciano, R., Pistorio, A., Catarsi, P., Canini, S., Karsenty, G., & Ravazzolo, R. (2004) · Physiological Genomics · doi:10.1152/physiolgenomics.00138.2004 · Cited by 140

Molecular Bases of the Regulation of Bone Remodeling by the Canonical Wnt Signaling Pathway

Glass, D. A., & Karsenty, G. (2006) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(05)73002-7 · Cited by 138

Control of histone modifications

Davie, J., & Spencer, V. A. (1999) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(1999)75:32+ · Cited by 146

Molecular biology of bone remodelling.

Rucci, N. (2008) · PubMed Central · Cited by 133

Efficient Adipocyte and Osteoblast Differentiation from Mouse Induced Pluripotent Stem Cells by Adenoviral Transduction

Tashiro, K., Inamura, M., Kawabata, K., Sakurai, F., Yamanishi, K., Hayakawa, T., & Mizuguchi, H. (2009) · Stem Cells · doi:10.1002/stem.108 · Cited by 132

The role of miR-31-modified adipose tissue-derived stem cells in repairing rat critical-sized calvarial defects

Deng, Y., Zhou, H., Zou, D., Xie, Q., Bi, X., Gu, P., & Fan, X. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.05.042 · Cited by 132

Reduced Sox9 Function Promotes Heart Valve Calcification Phenotypes In Vivo

Peacock, J. D., Levay, A. K., Gillaspie, D. B., Tao, G., & Lincoln, J. (2010) · Circulation Research · doi:10.1161/circresaha.109.213702 · Cited by 136

MECHANISMS IN ENDOCRINOLOGY: Micro-RNAs: targets for enhancing osteoblast differentiation and bone formation

Taipaleenmäki, H., Hokland, L. B., Chen, L., Kauppinen, S., & Kassem, M. S. (2011) · European Journal of Endocrinology · doi:10.1530/eje-11-0646 · Cited by 132

Tumor necrosis factor-α inhibits pre-osteoblast differentiation through its type-1 receptor

Abbas, S., Zhang, Y.-H., Clohisy, J. C. F., & Abu‐Amer, Y. (2003) · Cytokine · doi:10.1016/s1043-4666(03)00106-6 · Cited by 132

Uno, nessuno e centomila: Searching for the Identity of Mesodermal Progenitors

Bianco, P., & Cossu, G. (1999) · Experimental Cell Research · doi:10.1006/excr.1999.4592 · Cited by 132

Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype

Gersbach, C. A., Byers, B. A., Pavlath, G. K., & Garcı́a, A. J. (2004) · Experimental Cell Research · doi:10.1016/j.yexcr.2004.07.031 · Cited by 132

Activation of extracellular signal-regulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells.

Rubin, J., Murphy, T. C., Fan, X., Goldschmidt, M., & Taylor, W. R. (2002) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2002.17.8.1452 · Cited by 131

The RUNX2 Cistrome in Osteoblasts

Meyer, M. B., Benkusky, N. A., & Pike, J. W. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.552216 · Cited by 131

Prostate cancer cells induce osteoblast differentiation through a Cbfa1-dependent pathway.

Yang, J., Fizazi, K. S., Peleg, S., Sikes, C. R., Raymond, A. K., Jamal, N., Hu, M. C. ‐., Olivé, M., Martinez, L. A., Wood, C. G., et al. (2001) · PubMed · Cited by 131

Potential Role of Cbfa1, an Essential Transcriptional Factor for Osteoblast Differentiation, in Osteoclastogenesis: Regulation of mRNA Expression ofOsteoclast Differentiation Factor(ODF)

Gao, Y., Shinki, T., Yuasa, T., Kataoka-Enomoto, H., Komori, T., Suda, T., & Yamaguchi, A. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9643 · Cited by 130

Potent inhibitory action of red wine polyphenols on human breast cancer cells

Damianaki, A., Bakogeorgou, E., Kampa, M., Notas, G., Hatzoglou, A., Panagiotou, S., Gemetzi, C., Kouroumalis, E., Martin, P., & Castanas, E. (2000) · Journal of Cellular Biochemistry · doi:10.1002/1097-4644(20000901)78:3 · Cited by 314

Core-binding factor α1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5

Nishimura, R., Hata, K., Harris, S. E., Ikeda, F., & Yoneda, T. (2002) · Bone · doi:10.1016/s8756-3282(02)00826-8 · Cited by 131

Transcriptional Regulation of the Transforming Growth Factor-β-inducible Mouse Germ Line Ig α Constant Region Gene by Functional Cooperation of Smad, CREB, and AML Family Members

Zhang, Y. E., & Derynck, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001526200 · Cited by 130

The Osteoblast to Osteocyte Transition: Epigenetic Changes and Response to the Vitamin D3Hormone

St. John, H. C., Bishop, K. A., Meyer, M. B., Benkusky, N. A., Leng, N., Kendziorski, C., Bonewald, L. F., & Pike, J. W. (2014) · Molecular Endocrinology · doi:10.1210/me.2014-1091 · Cited by 127

Synergistic enhancement of human bone marrow stromal cell proliferation and osteogenic differentiation on BMP-2-derived and RGD peptide concentration gradients

Moore, N. M., Lin, N. J., Gallant, N. D., & Becker, M. L. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.01.019 · Cited by 138

Direct conversion of human fibroblasts into functional osteoblasts by defined factors

Yamamoto, K., Kishida, T., Sato, Y., Nishioka, K., Ejima, A., Fujiwara, H., Kubo, T., Yamamoto, T., Kanamura, N., & Mazda, O. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1420713112 · Cited by 134

Tensile Strain as a Regulator of Mesenchymal Stem Cell Osteogenesis

Kearney, E. M., Farrell, E., Prendergast, P. J., & Campbell, V. A. (2010) · Annals of Biomedical Engineering · doi:10.1007/s10439-010-9979-4 · Cited by 130

The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells

Chen, N. X., Duan, D., O’Neill, K. D., Wolisi, G. O., Koczman, J. J., LaClair, R. E., & Moe, S. M. (2006) · Kidney International · doi:10.1038/sj.ki.5001663 · Cited by 130

Microrough titanium surface affects biologic response in MG63 osteoblast‐like cells

Kim, M., Kim, C., Lim, Y., & Heo, S. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.31040 · Cited by 130

Chip-Based Comparison of the Osteogenesis of Human Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stem Cells under Mechanical Stimulation

Park, S., Sim, W. Y., Min, B., Yang, S. S., Khademhosseini, A., & Kaplan, D. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046689 · Cited by 130

Mechanical Signals as Regulators of Stem Cell Fate

Estes, B. T., Gimble, J. M., & Guilak, F. (2004) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(04)60004-4 · Cited by 130

Flavonoids of Herba Epimedii regulate osteogenesis of human mesenchymal stem cells through BMP and Wnt/β-catenin signaling pathway

Zhang, J., Guo, L., Chan, C.-Y., Meng, C.-L., Lin, M. C. M., Chen, Y., He, M., Leung, P., & Kung, H. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.08.012 · Cited by 130

Osteocrin, a Novel Bone-specific Secreted Protein That Modulates the Osteoblast Phenotype

Thomas, G. P., Moffatt, P., Salois, P., Gaumond, M.-H., Gingras, R., Godin, É., Miao, D., Goltzman, D., & Lanctôt, C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307310200 · Cited by 130

Berberine Promotes Osteoblast Differentiation by Runx2 Activation With p38 MAPK

Lee, H. W., Suh, J. H., Kim, H.-N., Kim, A., Park, S. Y., Shin, C. S., Choi, J., & Kim, J. B. (2008) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.080325 · Cited by 130

The Role of NELL-1, a Growth Factor Associated with Craniosynostosis, in Promoting Bone Regeneration

Zhang, X., Zara, J. N., Siu, R. K., Ting, K., & Soo, C. B. (2010) · Journal of Dental Research · doi:10.1177/0022034510376401 · Cited by 130

Mechanical strain induces osteogenic differentiation: Cbfa1 and Ets-1 expression in stretched rat mesenchymal stem cells

Qi, M., Hu, J., Zou, S., Chen, H.-Q., Zhou, H.-X., & Han, L. (2008) · International Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.ijom.2007.12.008 · Cited by 130

Cardiovascular calcification in patients with end-stage renal disease: A century-old phenomenon

Qunibi, W. Y., Nolan, C. A., & Ayus, J. C. (2002) · Kidney International · doi:10.1046/j.1523-1755.62.s82.15.x · Cited by 130

Vascular calcification and renal osteodystrophy relationship in chronic kidney disease

Moe, S. M. (2006) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2006.01665.x · Cited by 130

Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat

Lazarenko, O. P., Rzońca, S., Suva, L. J., & Lecka‐Czernik, B. (2005) · Bone · doi:10.1016/j.bone.2005.07.008 · Cited by 130

Osteoclast differentiation and gene regulation

Zhao, Q. (2006) · Frontiers in bioscience · doi:10.2741/2252 · Cited by 129

Childhood obesity, bone development, and cardiometabolic risk factors

Pollock, N. K. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.03.016 · Cited by 129

Myeloma cells suppress osteoblasts through sclerostin secretion

Colucci, S. C., Brunetti, G., Oranger, A., Mori, G., Sardone, F., Specchia, G., Rinaldi, E., Curci, P., Liso, V., Passeri, G., et al. (2011) · Blood Cancer Journal · doi:10.1038/bcj.2011.22 · Cited by 130

Targeting tumor–stromal interactions in bone metastasis

Esposito, M., & Kang, Y. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.10.006 · Cited by 129

Smad3 Interacts with JunB and Cbfa1/Runx2 for Transforming Growth Factor-β1-stimulated Collagenase-3 Expression in Human Breast Cancer Cells

Selvamurugan, N., Kwok, S., & Partridge, N. C. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312870200 · Cited by 133

Trans-activation of the Mouse Cartilage-Derived Retinoic Acid-Sensitive Protein Gene by Sox9

Xie, W., Zhang, X., Sakano, S., Lefèbvre, V., & Sandell, L. J. (1999) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1999.14.5.757 · Cited by 129

Wnt signaling activation during bone regeneration and the role of Dishevelled in chondrocyte proliferation and differentiation

Zhong, N., Gersch, R. P., & Hadjiargyrou, M. (2006) · Bone · doi:10.1016/j.bone.2005.12.008 · Cited by 129

Genetic control of cell differentiation in the skeleton

Ducy, P. F., & Karsenty, G. (1998) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(98)80037-9 · Cited by 129

On the role of subtype selective adenosine receptor agonists during proliferation and osteogenic differentiation of human primary bone marrow stromal cells

Costa, M. A., Barbosa, A. D., Neto, E., Sá‐Sousa, A., Freitas, R., Neves, J. M., Magalhães-Cardoso, M. T., Ferreirinha, F., & Correia‐de‐Sá, P. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22458 · Cited by 131

Dose‐ and time‐dependent effect of bioactive gel‐glass ionic‐dissolution products on human fetal osteoblast‐specific gene expression

Christodoulou, I., Buttery, L. D. K., Saravanapavan, P., Tai, G., Hench, L. L., & Polak, J. M. (2005) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.30249 · Cited by 128

The life cycle of chondrocytes in the developing skeleton

Shum, L., & Nuckolls, G. H. (2002) · Arthritis Research · doi:10.1186/ar396 · Cited by 128

Molecular mechanism of vitamin D receptor action

Issa, L. L., Leong, G. M., & Eisman, J. A. (1998) · Inflammation Research · doi:10.1007/s000110050360 · Cited by 129

Murine and Chicken Chondrocytes Regulate Osteoclastogenesis by Producing RANKL in Response to BMP2

Usui, M., Xing, L., Drissi, H., Zuscik, M. J., O’Keefe, R. J., Chen, D., & Boyce, B. F. (2007) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.071025 · Cited by 129

Chondrogenic differentiation of mesenchymal progenitor cells encapsulated in ultrahigh‐viscosity alginate

Steinert, A. F., Weber, M., Dimmler, A. W., Julius, C., Schütze, N., Nöth, U. A., Cramer, H., Eulert, J., Zimmermann, U., & Hendrich, C. (2003) · Journal of Orthopaedic Research® · doi:10.1016/s0736-0266(03)00100-1 · Cited by 128

A Genomic Approach to Identify Novel Progesterone Receptor Regulated Pathways in the Uterus during Implantation

Cheon, Y., Li, Q., Xu, X., DeMayo, F. J., Bagchi, I. C., & Bagchi, M. K. (2002) · Molecular Endocrinology · doi:10.1210/me.2002-0270 · Cited by 129

The many facets of the matricelluar protein periostin during cardiac development, remodeling, and pathophysiology

Norris, R. A., Moreno‐Rodriguez, R. A., Hoffman, S., & Markwald, R. R. (2009) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-009-0063-5 · Cited by 127

Influence of the TGF-β Superfamily on Osteoclasts/Osteoblasts Balance in Physiological and Pathological Bone Conditions

Jann, J., Gascon, S., Roux, S., & Faucheux, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207597 · Cited by 133

Transcriptional regulation of osteoblast differentiation during development

Karsenty, G. (1998) · Frontiers in bioscience · doi:10.2741/a326 · Cited by 39

Expression of sonic hedgehog downstream genes is modified in rat embryos exposed in utero to a distal inhibitor of cholesterol biosynthesis

Gofflot, F., Gaoua, W., Bourguignon, L., Roux, C., & Picard, J. J. (2001) · Developmental Dynamics · doi:10.1002/1097-0177(2000)9999:9999 · Cited by 27

Characterization of Osf1, an Osteoblast-specific Transcription Factor Binding to a Critical cis-acting Element in the MouseOsteocalcin Promoters

Schinke, T., & Karsenty, G. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.30182 · Cited by 73

Mesenchymal Stem Cells and Osteoblast Differentiation

Aubin, J. E., & Triffitt, J. T. (2002) · Elsevier eBooks · doi:10.1016/b978-012098652-1.50106-2 · Cited by 163

The Developmental Control of Osteoblast-Specific Gene Expression: Role of Specific Transcription Factors and the Extracellular Matrix Environment

Franceschi, R. T. (1999) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411990100010201 · Cited by 274