The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

Cai, H., & Harrison, D. G. (2000) · Circulation Research · doi:10.1161/01.res.87.10.840 · Cited by 3,839

NAD(P)H Oxidase: Role in Cardiovascular Biology and Disease

Griendling, K. K., Sorescu, D., & Ushio-Fukai, M. (2000) · Circulation Research · doi:10.1161/01.res.86.5.494 · Cited by 2,886

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

Griendling, K. K., Minieri, C. A., Ollerenshaw, J. D., & Alexander, R. W. (1994) · Circulation Research · doi:10.1161/01.res.74.6.1141 · Cited by 2,735

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Rajagopalan, S., Kurz, S. D., Münzel, T. F., Tarpey, M. M., Freeman, B. Α., Griendling, K. K., & Harrison, D. G. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118623 · Cited by 2,467

Matrix Metalloproteinases in Vascular Remodeling and Atherogenesis

Galis, Z. S., & Khatri, J. J. (2002) · Circulation Research · doi:10.1161/res.90.3.251 · Cited by 1,965

Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly.

Galis, Z. S., & Khatri, J. J. (2002) · PubMed · Cited by 1,787

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Landmesser, U., Dikalov, S., Price, S. R., McCann, L., Fukai, T., Holland, S. M., Mitch, W. E., & Harrison, D. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200314172 · Cited by 1,660

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Landmesser, U., Dikalov, S., Price, S. R., McCann, L. A., Fukai, T., Holland, S. M., Mitch, W. E., & Harrison, D. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci14172 · Cited by 1,652

Angiotensin II Type-1 Receptor Antagonism Attenuates the Inflammatory and Thrombogenic Responses to Hypercholesterolemia in Venules

Petnehazy, T., Stokes, K. Y., Russell, J. M., & Granger, D. N. (2005) · Hypertension · doi:10.1161/01.hyp.0000154085.27868.93 · Cited by 29

Targeting MicroRNA-192-5p, a Downstream Effector of NOXs (NADPH Oxidases), Reverses Endothelial DHFR (Dihydrofolate Reductase) Deficiency to Attenuate Abdominal Aortic Aneurysm Formation

Huang, K., Narumi, T., Zhang, Y., Li, Q., Murugesan, P., Wu, Y., Liu, N. M., & Cai, H. “. (2021) · Hypertension · doi:10.1161/hypertensionaha.120.15070 · Cited by 28

Desbalanço redox: NADPH oxidase como um alvo terapêutico no manejo cardiovascular

Rabelo, L. A., de Souza, V. N., da Fonseca, L. J. S., & Sampaio, W. O. (2010) · Arquivos Brasileiros de Cardiologia · doi:10.1590/s0066-782x2010000500018 · Cited by 28

Insulin-Mediated Oxidative Stress and DNA Damage in LLC-PK1 Pig Kidney Cell Line, Female Rat Primary Kidney Cells, and Male ZDF Rat Kidneys In Vivo

Othman, E. M., Kreissl, M. C., Kaiser, F. R., Arias-Loza, P.-A., & Stopper, H. (2013) · Endocrinology · doi:10.1210/en.2012-1768 · Cited by 28

Quantitative assessment of aortic sclerosis using ultrasonic backscatter

Ngo, D. T. M., Wuttke, R. D., Turner, S. P., Marwick, T. H., & Horowitz, J. D. (2004) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2004.06.012 · Cited by 28

Inhibition of gp91phox contributes towards normobaric hyperoxia afforded neuroprotection in focal cerebral ischemia

Tang, X., Liu, K. J., Ramu, J., Chen, Q., Li, T., & Liu, W. (2010) · Brain Research · doi:10.1016/j.brainres.2010.05.082 · Cited by 27

Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation

Hsieh, D. J., Ng, S., Zeng, R., Padma, V. V., Huang, C., & Kuo, W. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072608 · Cited by 27

NADPH Oxidase Isoforms in COPD Patients and Acute Cigarette Smoke-Exposed Mice: Induction of Oxidative Stress and Lung Inflammation

Wang, X., Murugesan, P., Zhang, P., Xu, S., Peng, L., Wang, C., & Cai, H. “. (2022) · Antioxidants · doi:10.3390/antiox11081539 · Cited by 27

Insulin-Stimulated NADH/NAD+ Redox State Increases NAD(P)H Oxidase Activity in Cultured Rat Vascular Smooth Muscle Cells

Yang, M., & KAHN, A. (2006) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2005.11.017 · Cited by 27

Oxidative stress exaggerates skeletal muscle contraction-evoked reflex sympathoexcitation in rats with hypertension induced by angiotensin II

Koba, S., Watanabe, R., Kano, N., & Watanabe, T. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00423.2012 · Cited by 27

New insights in the pharmacological therapy of arterial hypertension

Cogolludo, A. L., Pérez‐Vizcaíno, F., & Tamargo, J. L. (2005) · Current Opinion in Nephrology & Hypertension · doi:10.1097/01.mnh.0000168334.09454.1c · Cited by 27

Targeting Antioxidant and Antithrombotic Biotherapeutics to Endothelium

Carnemolla, R., Shuvaev, V. V., & Muzykantov, V. R. (2010) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0030-1253455 · Cited by 27

Oxidative Stress and Peroxisome Proliferator–Activated Receptors

Devchand, P. R., Ziouzenkova, O., & Plutzky, J. (2004) · Circulation Research · doi:10.1161/01.res.0000151331.69399.b2 · Cited by 29

Influence of specific endothelin-1 receptor blockers on hemodynamic parameters and antioxidant status of plasma in LPS-induced endotoxemia

Piechota-Polańczyk, A., & Gorąca, A. (2012) · Pharmacological Reports · doi:10.1016/s1734-1140(12)70941-6 · Cited by 26

A critical appraisal of erectile function in animal models of diabetes mellitus

Gür, S., Kadowitz, P. J., & Hellstrom, W. J. G. (2008) · International Journal of Andrology · doi:10.1111/j.1365-2605.2008.00928.x · Cited by 26

Preventive effect of l-carnitine and its derivatives on endothelial dysfunction and platelet aggregation

Mohammadi, M. R., Talasaz, A. H., & Alidoosti, M. (2016) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2016.06.009 · Cited by 26

CX3CL1/CX3CR1 Axis Contributes to Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation and Inflammatory Cytokine Production

Li, C., He, J., Zhong, X., Gan, H., & Xia, Y. (2018) · Inflammation · doi:10.1007/s10753-018-0736-4 · Cited by 26

Pediatric pulmonary hypertension: Roles of endothelin-1 and nitric oxide.

Black, S. M., Kumar, S., Wiseman, D. A., Ravi, K., Wedgwood, S., Ryzhov, V., & Fineman, J. R. (2007) · PubMed · Cited by 26

Superoxide anions modulate the effects of angiotensin-(1–7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex and sympathetic activity in rats

Li, P., Zhang, F., Zhou, Y., Cui, B., & Han, Y. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.07.048 · Cited by 27

Biphasic regulation of H2O2 on angiogenesis implicated NADPH oxidase

Mu, P., Liu, Q., & Zheng, R. (2010) · Cell Biology International · doi:10.1042/cbi20090092 · Cited by 26

Arterial aging: a brief review.

Mirea, O., Donoiu, I., & Pleşea, I. E. (2012) · PubMed · Cited by 26

Epigallocatechin gallate attenuates ET-1-induced contraction in carotid artery from type 2 diabetic OLETF rat at chronic stage of disease

Matsumoto, T., Watanabe, S., Kawamura, R., Taguchi, K., & Kobayashi, T. (2013) · Life Sciences · doi:10.1016/j.lfs.2013.11.016 · Cited by 26

Nox2 Deficiency Prevents Hypertension‐Induced Vascular Dysfunction and Hypertrophy in Cerebral Arterioles

Chan, S., & Baumbach, G. L. (2013) · International Journal of Hypertension · doi:10.1155/2013/793630 · Cited by 25

Influence of Diabetes-Induced Glycation and Oxidative Stress on the Human Rotator Cuff

Yoshikawa, T., Mifune, Y., Inui, A., Nishimoto, H., Yamaura, K., Mukohara, S., Shinohara, I., & Kuroda, R. (2022) · Antioxidants · doi:10.3390/antiox11040743 · Cited by 25

Safflor yellow B suppresses angiotensin II-mediated human umbilical vein cell injury via regulation of Bcl-2/p22phox expression

Wang, C., He, Y., Yang, M., Sun, H., Zhang, S., & Wang, C. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.08.018 · Cited by 25

Protein Tyrosine Phosphatase LMW-PTP Exhibits Distinct Roles Between Vascular Endothelial and Smooth Muscle Cells

Shimizu, H., TOYAMA, O., Shiota, M., Kim‐Mitsuyama, S., & Miyazaki, H. (2005) · Journal of Receptors and Signal Transduction · doi:10.1081/rrs-200047876 · Cited by 24

Human Vascular Smooth Muscle Function and Oxidative Stress Induced by NADPH Oxidase with the Clinical Implications

Takaishi, K., Kinoshita, H., Kawashima, S., & Kawahito, S. (2021) · Cells · doi:10.3390/cells10081947 · Cited by 25

Role of LOX-1 in Ang II-induced oxidative functional damage in renal tubular epithelial cells

Xu (2010) · International Journal of Molecular Medicine · doi:10.3892/ijmm_00000514 · Cited by 24

Nicorandil prevents sirolimus-induced production of reactive oxygen species, endothelial dysfunction, and thrombus formation

Aizawa, K., Takahari, Y., Higashijima, N., Serizawa, K., Yogo, K., Ishizuka, N., Endo, K., Fukuyama, N., Hirano, K., & Ishida, H. (2015) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2014.12.017 · Cited by 24

Hydroxysafflor yellow A suppress oleic acid-induced acute lung injury via protein kinase A

Wang, C., Huang, Q., Wang, C., Zhu, X., Duan, Y., Yuan, S., & Bai, X. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.07.021 · Cited by 24

Angiotensin IV-evoked vasoprotection is conserved in advanced atheroma

Vinh, A., Widdop, R. E., Chai, S. Y., & Gaspari, T. A. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.12.042 · Cited by 24

Mitochondrial Redox Control of Matrix Metalloproteinase Signaling in Resistance Arteries

Touyz, R. M. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000216428.90962.60 · Cited by 24

Macrophage Migration Inhibitory Factor: A Novel Inhibitor of Apoptosis Signal-Regulating Kinase 1–p38–Xanthine Oxidoreductase–Dependent Cigarette Smoke–Induced Apoptosis

Fallica, J., Varela, L., Johnston, L., Kim, B., Serebreni, L., Wang, L., Damarla, M., Kolb, T. M., Hassoun, P. M., & Damico, R. L. (2015) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2014-0403oc · Cited by 22

Involvement of NADPH oxidase in A2A adenosine receptor-mediated increase in coronary flow in isolated mouse hearts

Zhou, Z., Rajamani, U., Labazi, H., Tilley, S. L., Ledent, C. A., Teng, B., & Mustafa, S. J. (2015) · Purinergic Signalling · doi:10.1007/s11302-015-9451-x · Cited by 22

Antioxidants Reverse Age-Related Collateral Growth Impairment

Miller, S. J., Coppinger, B. J., Zhou, X., & Unthank, J. L. (2009) · Journal of Vascular Research · doi:10.1159/000235965 · Cited by 23

Increased ANG II sensitivity following recovery from acute kidney injury: role of oxidant stress in skeletal muscle resistance arteries

Phillips, S. A., Pechman, K. R., Leonard, E. C., Friedrich, J. L., Bian, J.-T., Beal, A. G., & Basile, D. P. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00448.2009 · Cited by 23

Modulation of Dilator Responses of Cerebral Arterioles by Extracellular Superoxide Dismutase

Kitayama, J., Yi, C., Faraci, F. M., & Heistad, D. D. (2006) · Stroke · doi:10.1161/01.str.0000245134.12145.ae · Cited by 23

Abrupt Reoxygenation of Microvascular Endothelial Cells After Hypoxia Activates ERK1/2 and JNK1, Leading to NADPH Oxidase‐Dependent Oxidant Production

YU, G., Peng, T., Feng, Q., & Tyml, K. (2007) · Microcirculation · doi:10.1080/10739680601131218 · Cited by 23

Aminoguanidine inhibits aortic hydrogen peroxide production, VSMC NOX activity and hypercontractility in diabetic mice

Oak, J., Youn, J.-Y., & Cai, H. “. (2009) · Cardiovascular Diabetology · doi:10.1186/1475-2840-8-65 · Cited by 23

NAD(P)H Oxidases in Coronary Artery Disease

Arora, S., Vaishya, R., Dabla, P. K., & Singh, B. M. (2010) · Advances in clinical chemistry · doi:10.1016/s0065-2423(10)50004-0 · Cited by 22

Superoxide Anions in Paraventricular Nucleus Modulate Adipose Afferent Reflex and Sympathetic Activity in Rats

Ding, L., Zhang, L., Gao, R., Chen, D., Wang, J., Gao, X.-Y., Kang, Y., & Zhu, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083771 · Cited by 22

The Monitoring of Protein Markers of Inflammation and Serum Lipid Concentration in Obese Subjects with Metabolic Syndrome

Puhalo-Sladoje, D., Kisić, B., & Miric, D. J. (2017) · Journal of Medical Biochemistry · doi:10.1515/jomb-2017-0009 · Cited by 22

Distinct Role of nox1, nox2, and p47 phox in Unstimulated Versus Angiotensin II-Induced NADPH Oxidase Activity in Human Venous Smooth Muscle Cells

Chose, O., Sansilvestri, P., Badier‐Commander, C., Bernhardt, F., Fabiani, J., Rupin, A., & Verbeuren, T. J. (2008) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e31815d781d · Cited by 23

Evaluation of role of telmisartan in combination with 5-fluorouracil in gastric cancer cachexia

Sukumaran, S., Patel, H. J., & Patel, B. M. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.04.029 · Cited by 22

Redox control of enzymatic functions: The electronics of life's circuitry

Bonini, M. G., Consolaro, M. E. L., Hart, P. C., Mao, M., de Abreu, A. L. P., & Master, А. M. (2014) · IUBMB Life · doi:10.1002/iub.1258 · Cited by 21

Interplay between the kinin B1receptor and inducible nitric oxide synthase in insulin resistance

Haddad, Y., & Couture, R. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13491 · Cited by 21

Exposure to maternal diabetes induces endothelial dysfunction and hypertension in adult male rat offspring

Yu, C., Chen, S., Wang, X., Wu, G., Zhang, Y., Fu, C., Hu, C., Liu, Z., Luo, X., Wang, J., et al. (2020) · Microvascular Research · doi:10.1016/j.mvr.2020.104076 · Cited by 21

Quercetin treatment protects the Achilles tendons of rats from oxidative stress induced by hyperglycemia

Yoshikawa, T., Mifune, Y., Inui, A., Nishimoto, H., Yamaura, K., Mukohara, S., Shinohara, I., & Kuroda, R. (2022) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-022-05513-4 · Cited by 21

Reduction of oxidative stress does not attenuate the development of angiotensin II-dependent hypertension in Ren-2 transgenic rats

Kopkan, L., Husková, Z., Vaňourková, Z., Thumová, M., Škaroupková, P., Malý, J., Kramer, H. J., Dvořák, P., & Červenka, L. (2009) · Vascular Pharmacology · doi:10.1016/j.vph.2009.06.001 · Cited by 21

Combination of Telmisartan with Cisplatin Controls Oral Cancer Cachexia in Rats

Patel, B. M., & Damle, D. (2013) · BioMed Research International · doi:10.1155/2013/642848 · Cited by 21

Genetic interleukin-10 deficiency causes vascular remodeling via the upregulation of Nox1

Dammanahalli, J. K., Wang, X., & Sun, Z. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834b22a0 · Cited by 21

The importance of sphingolipids and reactive oxygen species in cardiovascular development

Poloni, J. D. F., Chapola, H., Feltes, B. C., & Bonatto, D. (2014) · Biology of the Cell · doi:10.1111/boc.201400008 · Cited by 21

The Significance of Endothelial Dysfunction in Long COVID-19 for the Possible Future Pandemic of Chronic Kidney Disease and Cardiovascular Disease

Yanai, H., Adachi, H., Hakoshima, M., Katsuyama, H., & Sako, A. (2024) · Biomolecules · doi:10.3390/biom14080965 · Cited by 20

Cyanidin-3-glucoside suppresses TNF-α-induced cell proliferation through the repression of Nox activator 1 in mouse vascular smooth muscle cells: involvement of the STAT3 signaling

Luo, X., Shi, F., Xiao, Y., Song, F., Zou, T., Wang, M., Xia, M., & Ling, W. (2011) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-011-1144-3 · Cited by 21

Superoxide anion generation and oxidative stress in methylmercury-induced endothelial toxicity in vitro

Ghizoni, H., de Souza, V., Straliotto, M. R., Bem, A. F. D., Farina, M., & Hort, M. A. (2016) · Toxicology in Vitro · doi:10.1016/j.tiv.2016.10.010 · Cited by 20

Malfunction of Vascular Control in Lifestyle-Related Diseases: Oxidative Stress of Angiotensin II-induced Hypertension: Mitogen-Activated Protein Kinases and Blood Pressure Regulation

Kimura, S., Zhang, G., & Abe, Y. (2004) · Journal of Pharmacological Sciences · doi:10.1254/jphs.fmj04006x5 · Cited by 20

NADPH AND NADPH OXIDASE

Fisher, A. B., & Zhang, Q. (2006) · Elsevier eBooks · doi:10.1016/b0-12-370879-6/00252-0 · Cited by 20

Short-Term Consumption of a Dark Chocolate Containing Flavanols is Followed by a Significant Decrease in Normotensive Population

AlFaris, N. A. (2008) · Pakistan Journal of Nutrition · doi:10.3923/pjn.2008.773.781 · Cited by 19

Selective inhibition of NADPH oxidase reverses the over contraction of diabetic rat aorta

Rehman, A. U., Dugic, E., Benham, C. D., Lione, L. A., & Mackenzie, L. S. (2013) · Redox Biology · doi:10.1016/j.redox.2013.12.002 · Cited by 19

Endothelin-1-Induced Impairment of Endothelium-Dependent Relaxation in Aortas Isolated from Controls and Diabetic Rats

Kamata, K., Kanie, N., Matsumoto, T., & Kobayashi, T. (2004) · Journal of Cardiovascular Pharmacology · doi:10.1097/01.fjc.0000166241.49453.e9 · Cited by 19

Exercise to Prevent Accelerated Vascular Aging in People Living With HIV

Jones, R., Robinson, A. T., Beach, L. B., Lindsey, M. L., Kirabo, A., Hinton, A. O., Jr., Erlandson, K. M., & Jenkins, N. D. M. (2024) · Circulation Research · doi:10.1161/circresaha.124.323975 · Cited by 23

Nifedipine Activates PPARγ and Exerts Antioxidative Action Through Cu/ZnSOD Independent of Blood-pressure Lowering in SHRSP

Hashimoto, R., Umemoto, S., Guo, F., Umeji, K., Itoh, S., Kishi, H., Kobayashi, S., & Matsuzaki, M. (2010) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.4556 · Cited by 18

Fetal cardiomyocyte phenotype, ketone body metabolism, and mitochondrial dysfunction in the pathology of atrial fibrillation

Brown, S. M., Larsen, N. K., Thankam, F. G., & Agrawal, D. K. (2020) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-03980-8 · Cited by 17

Viral Vector-Mediated 12/15-Lipoxygenase Overexpression in Vascular Smooth Muscle Cells Enhances Inflammatory Gene Expression and Migration

Dwarakanath, R. S., Sahar, S., Lanting, L. L., Wang, N., Stemerman, M. B., Natarajan, R. D., & Reddy, M. A. (2007) · Journal of Vascular Research · doi:10.1159/000109966 · Cited by 18

3,3′,4′,5,7-Pentamethylquercetin reduces angiotensin II-induced cardiac hypertrophy and apoptosis in rats

Mao, Z., Liang, Y., Du, X., & Sun, Z. (2009) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y09-069 · Cited by 18

KLF2-mediated disruption of PPAR-γ signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow

Morris, C. J., Kameny, R. J., Boehme, J. B., Gong, W., He, Y., Zhu, T., Maltepe, E., Raff, G. W., Fineman, J. R., & Datar, S. A. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00635.2017 · Cited by 18

Role of fenofibrate alone and in combination with telmisartan on renal ischemia/reperfusion injury

Bhalodia, Y. S., Sheth, N. R., Vaghasiya, J. D., & Jivani, N. P. (2010) · Renal Failure · doi:10.3109/0886022x.2010.504911 · Cited by 17

Synthesis of N , N ′-bis(1,5-dimethyl-2-phenyl-1,2-dihydro-3-oxopyrazol-4-yl) sebacamide that ameliorate osteoarthritis symptoms and improve bone marrow matrix structure and cartilage alterations induced by monoiodoacetate in the rat model: “Suggested potent anti-inflammatory agent against COVID-19”

Refat, M. S. E.-D., Hamza, R. Z., Adam, A., Saad, H., Gobouri, A. A., Al‐Salmi, F. A., Altalhi, T., & El‐Megharbel, S. M. (2020) · Human & Experimental Toxicology · doi:10.1177/0960327120945779 · Cited by 17

Changes in the subcellular distribution of NADPH oxidase subunit p47phox in dendrites of rat dorsomedial nucleus tractus solitarius neurons in response to chronic administration of hypertensive agents

Glass, M. J., Chan, J., Frys, K. A., Oselkin, M., Tarsitano, M., Iadecola, C., & Pickel, V. M. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.02.016 · Cited by 17

Renoprotective effect of a combination of garlic and telmisartan against ischemia/reperfusion-induced kidney injury in obese rats

Ali, S. I., Alhusseini, N. F., Atteia, H. H., Idris, R. A. E.-S., & Hasan, R. A. (2016) · Free Radical Research · doi:10.1080/10715762.2016.1211644 · Cited by 18

The Endothelin Receptor Antagonist CPU0213 is More Effective Than Aminoguanidine to Attenuate Isoproterenol-induced Vascular Abnormality by Suppressing Overexpression of NADPH Oxidas, ETA, ETB, and MMP9 in the Vasculature

Xu, J., Li, N., Dai, D., Yu, F., & Dai, Y. (2008) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e31817dfc8f · Cited by 17

A reappraisal of the genomic organization of human Nox1 and its splice variants

Harper, R. W., Xu, C., Souček, K., Setiadi, H., & Eiserich, J. P. (2005) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2004.12.021 · Cited by 17

Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit

Shukla, N., Koupparis, A. J., Jones, R. A. W., Angelini, G. D., Persad, R. A., & Jeremy, J. Y. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.12.003 · Cited by 17

Multifocal Angiostatic Therapy: An Update

McCarty, M. F., & Block, K. I. (2005) · Integrative Cancer Therapies · doi:10.1177/1534735405282475 · Cited by 17

Oxidant signaling in lung cells

Frey, R. S., & Malik, A. B. (2004) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00337.2003 · Cited by 16

REPRINT Treatment of Hypertension in the Prevention and Management of Ischemic Heart Disease

Rosendorff, C., Black, H. R., Cannon, C. P., Gersh, B. J., Gore, J. M., Izzo, J. L., Kaplan, N. M., O’Connor, C. M., O’Gara, P. T., & Oparil, S. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.183885 · Cited by 18

Evaluation of apocynin in vitro on high glucose-induced oxidative stress on tenocytes

Kurosawa, T., Mifune, Y., Inui, A., Nishimoto, H., Ueda, Y., Kataoka, T., Yamaura, K., Mukohara, S., & Kuroda, R. (2020) · Bone and Joint Research · doi:10.1302/2046-3758.991.bjr-2019-0074.r1 · Cited by 16

Enalapril Alone or Co-Administered with Losartan Rescues Cerebrovascular Dysfunction, but not Mnemonic Deficits or Amyloidosis in a Mouse Model of Alzheimer’s Disease

Ongali, B., Nicolakakis, N., Tong, X.-K., Aboulkassim, T., Imboden, H., & Hamel, E. (2016) · Journal of Alzheimer’s Disease · doi:10.3233/jad-150868 · Cited by 16

Oxidant Stress in Renal Pathophysiology

Abid, M. R., Razzaque, M. S., & Taguchi, T. (2005) · KARGER eBooks · doi:10.1159/000086058 · Cited by 16

Role of NADPH Oxidase in Hypertension and Diabetic Nephropathy

Onozato, M. L., & Tojo, A. (2005) · Current Hypertension Reviews · doi:10.2174/1573402052952825 · Cited by 16

Statins Mitigate Stress-Related Vascular Aging and Atherosclerosis in apoE-Deficient Mice Fed High Fat-Diet: The Role of Glucagon-Like Peptide-1/Adiponectin Axis

Lei, Y., Cui, Q., Yang, G., Piao, L., Inoue, A., Wu, H., Li, X., Kuzuya, M., & Cheng, X. W. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.687868 · Cited by 15

Therapeutic role of telmisartan against acetaminophen hepatotoxicity in mice

Fouad, A. A., Al-Mulhim, A. S., Jresat, I., & Gomaa, W. M. (2012) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.07.049 · Cited by 15

Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption

Pavlov, T. S., Levchenko, V., & Staruschenko, A. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.558262 · Cited by 15

NADPH oxidase 4 contributes to TRPV4-mediated endothelium-dependent vasodilation in human arterioles by regulating protein phosphorylation of TRPV4 channels

Xie, Y., Nishijima, Y., Zinkevich, N. S., Korishettar, A., Fang, J., Mathison, A., Zimmermann, M. T., Wilcox, D. A., Gutterman, D. D., Shen, Y., et al. (2022) · Basic Research in Cardiology · doi:10.1007/s00395-022-00932-9 · Cited by 15

Impaired compensation to femoral artery ligation in diet-induced obese mice is primarily mediated via suppression of collateral growth by Nox2 and p47phox

Distasi, M. R., Mund, J. A., Bohlen, H. G., Miller, S. J., Ingram, D. A., Dalsing, M. C., & Unthank, J. L. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00180.2015 · Cited by 17

Myeloperoxidase impairs the contractile function in isolated human cardiomyocytes

Kalász, J., Pásztor, E. T., Fagyas, M., Balogh, Á., Tóth, A., Csató, V., Edes, I. F., Papp, Z., & Borbély, A. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.02.036 · Cited by 15

Atrial natriuretic peptide prevents diabetes-induced endothelial dysfunction

Woodman, O. L., Malakul, W., Cao, A. H., Xu, Q., & Ritchie, R. H. (2008) · Life Sciences · doi:10.1016/j.lfs.2008.01.016 · Cited by 15

Effects of the use of assisted reproduction and high-caloric diet consumption on body weight and cardiovascular health of juvenile mouse offspring

Schenewerk, A. L., Ramirez‐Perez, F. I., Foote, C. A., Ji, T., Martinez‐Lemus, L. A., & Rivera, R. M. (2013) · Reproduction · doi:10.1530/rep-13-0354 · Cited by 15

The interrelation of the angiotensin and endothelin systems on the modulation of NAD(P)H oxidaseThis paper is one of a selection of papers published in this Special issue, entitled Young Investigator's Forum.

Laplante, M., & de Champlain, J. (2006) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y05-146 · Cited by 16

What Cardiologists Should Know About Calcium Ion Channels and Their Regulation by Reactive Oxygen Species

Hool, L. C. (2007) · Heart Lung and Circulation · doi:10.1016/j.hlc.2007.01.005 · Cited by 15

Time-dependent transition of tempol-sensitive reduction of blood pressure in angiotensin II-induced hypertension

Kimura, S., Zhang, G., Nagai, Y., Miyata, K., Nishiyama, A., Shokoji, T., Yao, L., Fan, Y.-Y., Rahman, M., Fujisawa, Y., et al. (2004) · Journal of Hypertension · doi:10.1097/00004872-200411000-00019 · Cited by 15

Expanding telmisartan’s therapeutic horizon: exploring its multifaceted mechanisms beyond cardiovascular disorders

Ahire, Y. S., Bairagi, V. A., Somavanshi, D., Jadhav, S. R., Jadhav, S. B., & Jagtap, S. D. (2024) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-024-00655-9 · Cited by 14

Reactive oxygen and nitrogen species: Implications for cardiovascular device engineering

Kader, K. N., & Coyle, C. H. (2007) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.30777 · Cited by 14

Protection against tacrolimus-induced cardiotoxicity in rats by olmesartan and aliskiren

Al-Harbi, N. O., Imam, F., Nadeem, A., Al‐Harbi, M. M., Iqbal, M., Rahman, S., Al-Hosaini, K. A., & Bahashwan, S. (2014) · Toxicology Mechanisms and Methods · doi:10.3109/15376516.2014.963773 · Cited by 15

Atorvastatin treatment affects atrial ion currents and their tachycardia-induced remodeling in rabbits

Laszlo, R., Menzel, K. A., Bentz, K., Schreiner, B., Kettering, K., Eick, C., & Schreieck, J. (2010) · Life Sciences · doi:10.1016/j.lfs.2010.09.010 · Cited by 14

Impaired Aortic Contractility to Uridine Adenosine Tetraphosphate in Angiotensin II-Induced Hypertensive Mice: Receptor Desensitization?

Zhou, Z., Yadav, V., Sun, C., Teng, B., & Mustafa, J. S. (2016) · American Journal of Hypertension · doi:10.1093/ajh/hpw163 · Cited by 14

Superoxide anions modulate the performance of apelin in the paraventricular nucleus on sympathetic activity and blood pressure in spontaneously hypertensive rats

Zhao, Y., Li, Y., Li, Z., Xu, B., Chen, P., & Yang, X. (2018) · Peptides · doi:10.1016/j.peptides.2018.12.005 · Cited by 13

Cross-linking of MHC class II molecules interferes with phorbol 12,13-dibutyrate-induced differentiation of resting B cells by inhibiting Rac-associated ROS-dependent ERK/p38 MAP kinase pathways leading to NF-κB activation

Yang, H., Kim, J., Chung, G., Lee, J., & Jang, Y. (2006) · Molecular Immunology · doi:10.1016/j.molimm.2006.08.017 · Cited by 14

Development of Adjunctive Therapies for Bacterial Meningitis and Lessons From Knockout Mice

Paul, R. H., Koedel, U., & Pfister, H. (2005) · Neurocritical Care · doi:10.1385/ncc:2:3:313 · Cited by 14

Chronic stress, gut microbiota, and immunity: interconnections and implications for health

Jia, H., Guo, X., Wei, Y., Can, C., He, N., Zhang, H., Yang, X., Wu, H., Liu, W., & Ma, D. (2025) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05376-y · Cited by 14

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Drummond, G. R., Selemidis, S., Griendling, K. K., & Sobey, C. G. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3403 · Cited by 899

Vascular NAD(P)H oxidases: specific features, expression, and regulation

Lassegue, B. P., & Clempus, R. E. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00758.2002 · Cited by 1,026

Delineating the NOX-Mediated Promising Therapeutic Strategies for the Management of Various Cardiovascular Disorders: A Comprehensive Review

Upadhyay, R. K., Kumar, K., Vishwakarma, V. K., Singh, N., Narang, R., Parakh, N., Yadav, M., Yadav, S., Kumar, S., Goyal, A., et al. (2024) · Current Vascular Pharmacology · doi:10.2174/0115701611308870240910115023 · Cited by 6

NADPH Oxidases in Cardiovascular Health and Disease

Cave, A. C., Brewer, A. C., Narayanapanicker, A., Ray, R., Grieve, D. J., Walker, S., & Shah, A. M. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.691 · Cited by 630

NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition

Selemidis, S., Sobey, C. G., Wingler, K., Schmidt, H. H. H. W., & Drummond, G. R. (2008) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.08.005 · Cited by 249