The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
Abstract
Activation of vascular NAD(P)H oxidases and the production of reactive oxygen species (ROS) by these enzyme systems are common in cardiovascular disease. In the past several years, a new family of NAD(P)H oxidase subunits, known as the non-phagocytic NAD(P)H oxidase (NOX) proteins, have been discovered and shown to play a role in vascular tissues. Recent studies make clearer the mechanisms of activation of the endothelial and vascular smooth muscle NAD(P)H oxidases. ROS produced following angiotensin II-mediated stimulation of NAD(P)H oxidases signal through pathways such as mitogen-activated protein kinases, tyrosine kinases and transcription factors, and lead to events such as inflammation, hypertrophy, remodeling and angiogenesis. Studies in mice that are deficient in p47(phox) and gp91(phox) (also known as NOX2) NAD(P)H oxidase subunits show that ROS produced by these oxidases contribute to cardiovascular diseases including atherosclerosis and hypertension. Recently, efforts have been devoted to developing inhibitors of NAD(P)H oxidases that will provide useful experimental tools and might have therapeutic potential in the treatment of human diseases.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The current knowledge about NOX enzymes in the cardiovascular system indicates that NOX2 is usually the main player in the development of pathological conditions and increased NOX2 activity is linked to vascular disease (142, 252, 478).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [142]
In the citing paper
“The current knowledge about NOX enzymes in the cardiovascular system indicates that NOX2 is usually the main player in the development of pathological conditions and increased NOX2 activity is linked to vascular disease (142, 252, 478).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [142]
Citations
Cites
2 retracted
Ushio‐Fukai, M., Tang, Y., Fukai, T., Dikalov, S., Ma, Y., Fujimoto, M., Quinn, M. T., Pagano, P. J., Johnson, C., & Alexander, R. W. (2002) · Circulation Research · doi:10.1161/01.res.0000046227.65158.f8 · Cited by 466
RetractedUshio‐Fukai, M., Griendling, K. K., Becker, P. L., Hilenski, L. L., Halleran, S., & Alexander, R. W. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.21.4.489 · Cited by 283
Self-citationRetractedEndothelial dysfunction in cardiovascular diseases: the role of oxidant stress
Cai, H., & Harrison, D. G. (2000) · Circulation Research · doi:10.1161/01.res.87.10.840 · Cited by 3,839
Self-citationNAD(P)H Oxidase: Role in Cardiovascular Biology and Disease
Griendling, K. K., Sorescu, D., & Ushio-Fukai, M. (2000) · Circulation Research · doi:10.1161/01.res.86.5.494 · Cited by 2,886
Self-citationAngiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
Griendling, K. K., Minieri, C. A., Ollerenshaw, J. D., & Alexander, R. W. (1994) · Circulation Research · doi:10.1161/01.res.74.6.1141 · Cited by 2,735
Self-citationRajagopalan, S., Kurz, S. D., Münzel, T. F., Tarpey, M. M., Freeman, B. Α., Griendling, K. K., & Harrison, D. G. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118623 · Cited by 2,467
Self-citationMatrix Metalloproteinases in Vascular Remodeling and Atherogenesis
Galis, Z. S., & Khatri, J. J. (2002) · Circulation Research · doi:10.1161/res.90.3.251 · Cited by 1,965
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly.
Galis, Z. S., & Khatri, J. J. (2002) · PubMed · Cited by 1,787
Landmesser, U., Dikalov, S., Price, S. R., McCann, L., Fukai, T., Holland, S. M., Mitch, W. E., & Harrison, D. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200314172 · Cited by 1,660
Self-citationLandmesser, U., Dikalov, S., Price, S. R., McCann, L. A., Fukai, T., Holland, S. M., Mitch, W. E., & Harrison, D. G. (2003) · Journal of Clinical Investigation · doi:10.1172/jci14172 · Cited by 1,652
Self-citation
Research works printed but not linked: 4
- Fukui, 1997, p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats, Circ. Res., 80, 45, 10.1161/01.RES.80.1.45 · DOI · Paper page
- Ushio-Fukai, 2002, Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis, Circ. Res., 91, 1160, 10.1161/01.RES.0000046227.65158.F8 · DOI
- Suh, 1999, Cell transformation by the superoxide-generating oxidase Mox1, Nature, 401, 79, 10.1038/43459 · DOI · Paper page
- Engels, 1992, Effects of apocynin, a drug isolated from the roots of Picrorhiza kurroa, on arachidonic acid metabolism, FEBS Lett., 305, 254, 10.1016/0014-5793(92)80680-F · DOI
Cited by
Sorted by citations
Items 501–600 of 687
Cellular crosstalk between TNF-α, NADPH oxidase, PKCβ2, and C2GNT in human leukocytes.
Tarr, J., Ding, N., Kaul, K., Antonell, A., Pérez-Jurado, L., & Chibber, R. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2011.12.003 · Cited by 12
Chen, W., Liu, D., Huo, Y., Wu, Z., & Sun, Y. (2014) · International Journal of Biological Sciences · doi:10.7150/ijbs.8081 · Cited by 13
Pathophysiology of Primary Hypertension
Carey, R. M. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374530-9.00020-6 · Cited by 13
Han, X., Shaligram, S. S., Zhang, R., Anderson, L. C., & Rahimian, R. (2015) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2015-0272 · Cited by 13
Apocynin regulates cytokine production of CD8+ T cells
Nam, S., Oh, I. S., Yoon, Y. H., Kwon, B. I., Kang, W., Kim, H. J., Nahm, S. H., Choi, Y., Lee, S., Racanelli, V., et al. (2013) · Clinical and Experimental Medicine · doi:10.1007/s10238-013-0241-x · Cited by 13
Reactive Oxygen Species and the Cardiovascular System
Montezano, A. C. I., & Touyz, R. M. (2012) · Colloquium Series on Integrated Systems Physiology From Molecule to Function · doi:10.4199/c00043ed1v01y201112isp032 · Cited by 14
Gairola, C. G., Howatt, D. A., & Daugherty, A. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.02.035 · Cited by 13
de Oliveira, J. C., Antonietto, C. R. K., Scalabrini, A. C., Marinho, T. S., Pernomian, L., Corrêa, J. W. D. N., & Restini, C. B. A. (2012) · Open Journal of Medicinal Chemistry · doi:10.4236/ojmc.2012.23008 · Cited by 13
Redox Control of Blood Coagulation
Görlach, A. (2004) · Antioxidants and Redox Signaling · doi:10.1089/1523086041361668 · Cited by 13
Leukocyte-Dependent Responses of the Microvasculature to Chronic Angiotensin II Exposure
Yıldırım, A., Russell, J., Yan, L.-S. S., Senchenkova, E. Y., & Granger, D. N. (2012) · Hypertension · doi:10.1161/hypertensionaha.112.198465 · Cited by 13
Shin, Y. K., Han, A. Y., Hsieh, Y.-S., Kwon, S., Kim, J., Lee, K., & Seol, G. H. (2019) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.13140 · Cited by 12
Singh, N., Sharma, G., Singh, N., & Hanif, K. (2012) · International Journal of Stroke · doi:10.1111/j.1747-4949.2012.00916.x · Cited by 12
Effect of telmisartan in experimentally induced diabetetes mellitus in rats.
Hamed, A. A., & Malek, H. A. (2007) · Europe PMC (PubMed Central) · Cited by 12
Jiang, J., Kang, H., Song, X., Huang, S., Li, S., & Xu, J. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms14010807 · Cited by 13
Bégorre, M.-A., Dib, A., Habchi, K., Guihot, A., Bourreau, J., Vessières, E., Blondeau, B., Loufrani, L., Chabbert, M., Henrion, D., et al. (2017) · Scientific Reports · doi:10.1038/srep45625 · Cited by 12
Punica granatum attenuates angiotensin-II induced hypertension in Wistar rats.
Waghulde, H., Mohan, M., Kasture, S. B., & Balaraman, R. (2010) · International Journal of PharmTech Research · Cited by 12
Haddad, Y., & Couture, R. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00861 · Cited by 12
Morbidelli, L., Donnini, S., & Ziche, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816545-4.00004-9 · Cited by 12
NOX Modifiers—Just a Step Away from Application in the Therapy of Airway Inflammation?
Wieczfińska, J., Sokołowska, M., & Pawliczak, R. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5783 · Cited by 12
de Beer, V. J., Sorop, O., Pijnappels, D. A., Dekkers, D. H. W., Boomsma, F., Lamers, J. M. J., Duncker, D. J., & Merkus, D. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01163.2007 · Cited by 12
Vidrio, H. (2003) · Autonomic and Autacoid Pharmacology · doi:10.1111/j.1474-8673.2004.00296.x · Cited by 12
Peripheral vascular remodeling during ischemia
Lin, S., Lin, R., Zhang, H., Xu, Q., & He, Y. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1078047 · Cited by 11
Okada, Y. (2024) · The Journal of Physiological Sciences · doi:10.1186/s12576-024-00926-3 · Cited by 12
Ramirez‐Perez, F. I., Schenewerk, A. L., Coffman, K. L., Foote, C. A., Ji, T., Rivera, R. M., & Martinez‐Lemus, L. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112651 · Cited by 11
Gasparini, P. V. F., Matias, A. M., Sales, S. T., Sarter, J. B. B., Siqueira, J. S., Corrêa, C. R., Lima‐Leopoldo, A. P., & Leopoldo, A. S. (2021) · Cellular Physiology and Biochemistry · doi:10.33594/000000441 · Cited by 11
Ahmed, M. A. (2013) · Europe PMC (PubMed Central) · Cited by 11
Modulation of NADPH oxidase activity by known uraemic retention solutes
Schulz, A. M., Terne, C., Jankowski, V., Cohen, G., Schaefer, M., Boehringer, F., Tepel, M., Kunkel, D., Zidek, W., Jankowski, J., et al. (2014) · European Journal of Clinical Investigation · doi:10.1111/eci.12297 · Cited by 12
Sánchez‐del‐Campo, L., Chazarra, S., Montenegro, M. F., Cabezas‐Herrera, J., & Rodríguez‐López, J. N. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22656 · Cited by 11
Selective inhibition of NADPH-oxidase isoforms as a therapeutic strategy in hypertension
Miller, A. A., Drummond, G. R., & Sobey, C. G. (2005) · Drug Discovery Today Therapeutic Strategies · doi:10.1016/j.ddstr.2005.08.002 · Cited by 11
LIU, J.-J., LU, Y., Ping, N.-N., Li, X., LIN, Y.-X., & Li, C. (2017) · Physiological Research · doi:10.33549/physiolres.933257 · Cited by 11
Ezetimibe and Reactive Oxygen Species
Yamaoka‐Tojo, M., Tojo, T., Takahira, N., Masuda, T., & Izumi, T. (2010) · Current Vascular Pharmacology · doi:10.2174/157016111793744652 · Cited by 11
Murugesan, P., Zhang, Y., Youn, J. Y., & Cai, H. “. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102348 · Cited by 9
Self-citationAortic coarctation induces oxidative stress in rat tissues
Polizio, A. H., Gorzalczany, S. B., Taira, C. A., & Peña, C. (2006) · Life Sciences · doi:10.1016/j.lfs.2006.02.004 · Cited by 10
Tawa, M., Yamamizu, K., Geddawy, A., Shimosato, T., Imamura, T., Ayajiki, K., & Okamura, T. (2011) · Journal of Pharmacological Sciences · doi:10.1254/jphs.11031fp · Cited by 10
Extracellular cyclophilin A induces cardiac hypertrophy via the ERK/p47phox pathway
Cao, M., Mao, Z., Peng, M., Zhao, Q., Sun, X., Yan, J., & Yuan, W. (2020) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2020.110990 · Cited by 10
Yuan, B., Wei, Y., Wen, X., Li, C., Gao, L., Li, B., Wang, D., Cui, L., & Li, Y. (2018) · Inhalation Toxicology · doi:10.1080/08958378.2018.1558315 · Cited by 9
Ehrlich, K., Ida, K., Mahlapuu, R., Kairane, Č., Oit-Wiscombe, I., Zilmer, M., & Soomets, U. (2009) · Free Radical Research · doi:10.1080/10715760902918691 · Cited by 9
Qin, X., Hou, X., Liang, T., Chen, L., Lu, T., & Li, Q. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.11.020 · Cited by 9
Biological Effects of Cis- Versus Trans-Resveratrol
Orallo, F. (2005) · CRC Press eBooks · doi:10.1201/9781420026474.ch24 · Cited by 9
Vascular Remodeling in Health and Disease
Melo, L. G., Gnecchi, M., Ward, C. A., & Dzau, V. J. (2007) · Springer eBooks · doi:10.1007/978-1-84628-715-2_74 · Cited by 11
Laszlo, R., Bentz, K., & Schreieck, J. (2011) · General Physiology and Biophysics · doi:10.4149/gpb_2011_01_11 · Cited by 9
Effect of captopril and the bradykinin–PKC pathway on ROS production in type 1 diabetic rats
de Araújo, G. R., de Faria, K. G., de Lima, W. G., Pádua, B. D. C., Rossoni, J. V., de Souza, A. M. A., Chianca, D. A., Silva, M. E., Pedrosa, M. L., Chaves, M. M., et al. (2011) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y11-097 · Cited by 9
Lipid peroxidation and renal injury in renal ischemic reperfusion: effect ofangiotensin inhibition.
Seujang, Y., Kittikowit, W., Eiam‐Ong, S., & Eiam‐Ong, S. (2006) · PubMed · Cited by 9
NAD(P)H oxidase-induced oxidative stress in sympathetic ganglia of apolipoprotein E deficient mice
Ma, X., Zhang, H. J., Whiteis, C. A., Tian, X., Davisson, R. L., Kregel, K. C., Abboud, F. M., & Chapleau, M. W. (2006) · Autonomic Neuroscience · doi:10.1016/j.autneu.2006.02.005 · Cited by 9
Transforming Growth Factor-α, a Novel Mediator of Strain-Induced Vascular Remodeling
Kouri, F. M., & Eickelberg, O. (2006) · Circulation Research · doi:10.1161/01.res.0000239429.72678.e1 · Cited by 9
Groban, L., Lindsey, S. H., Wang, H., Lin, M. S., Kassik, K. A., Machado, F. S. M., & Carter, C. S. (2011) · AGE · doi:10.1007/s11357-011-9283-8 · Cited by 8
Northcott, C. A., Billecke, S. S., Craig, T. A., Hinojosa‐Laborde, C., Patel, K. P., Chen, A. F., D’Alecy, L. G., & Haywood, J. R. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00562.2011 · Cited by 8
Telmisartan ameliorates carbon tetrachloride‐induced acute hepatotoxicity in rats
Atawia, R. T., Esmat, A., Elsherbiny, D. A., & El‐Demerdash, E. (2016) · Environmental Toxicology · doi:10.1002/tox.22240 · Cited by 8
Pathophysiology of Primary Hypertension
Carey, R. M. (2008) · Comprehensive physiology · doi:10.1002/cphy.cp020418 · Cited by 9
Frara, N. A., Giaddui, D., Braverman, A. S., Jawawdeh, K., Wu, C., Ruggieri, M. R., & Barbe, M. F. (2023) · PLoS ONE · doi:10.1371/journal.pone.0287212 · Cited by 7
Recent advances in gene therapy for atrial fibrillation
Yoo, S., Geist, G. E., Pfenniger, A., Rottmann, M., & Arora, R. (2021) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.15116 · Cited by 8
Cai, H. “. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00414.2005 · Cited by 7
Self-citationSato, K., Corbett, J. T., Mason, R. P., & Kadiiska, M. B. (2012) · Free Radical Research · doi:10.3109/10715762.2012.667089 · Cited by 7
Angiogenesis in the Metabolic Syndrome
Soares, R. A. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9701-0_5 · Cited by 6
Yıldırım, A., Senchenkova, E. Y., & Granger, D. N. (2016) · Microvascular Research · doi:10.1016/j.mvr.2016.01.002 · Cited by 7
Reid, M., Spence, J. R., Nwokocha, M., Palacios, J. C., & Nwokocha, C. R. (2018) · Studies in natural products chemistry · doi:10.1016/b978-0-444-64056-7.00002-7 · Cited by 6
Joe, Y., Uddin, M. J., Park, J., Ryu, J., Cho, G. J., Park, J. W., Choi, H., Ho, M., Ryter, S. W., & Chung, H. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109524 · Cited by 6
Parga, J. A., Rodríguez‐Pallares, J., Joglar, B., Díaz-Ruiz, C., Guerra, M. J., & Labandeira-García, J. L. (2010) · Developmental Dynamics · doi:10.1002/dvdy.22474 · Cited by 6
Fong, P. P., Stafforini, D. M., Brown, N. J., & Pretorius, M. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.04.023 · Cited by 6
Rang, H. P., Dale, M. M., Ritter, J., & Flower, R. J. (2007) · Elsevier eBooks · doi:10.1016/b978-0-443-06911-6.50024-4 · Cited by 6
Pharmacological Compounds with Antioxidant Activity
Dikalov, S., & Harrison, D. G. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-387-29553-4_7 · Cited by 4
Self-citationMa, Y., Xiao, H., Shen, S., & Pan, D. (2024) · Neurological Research · doi:10.1080/01616412.2024.2321014 · Cited by 5
Rosendorff, C., Lackland, D. T., Allison, M., Aronow, W. S., Black, H. R., Blumenthal, R. S., Cannon, C. P., de Lemos, J. A., Elliott, W. J., Findeiss, L., et al. (2015) · Cited by 5
Tong, M., Wang, J., Ji, Y., Chen, X., Wang, J., Wang, S., Ruan, L., Cui, H., Zhou, Y., Zhang, Q., et al. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.4741 · Cited by 5
Cardiac and Vascular Renin-Angiotensin Systems
Kumar, R., Baker, K. M., & Pan, J. (2007) · Humana Press eBooks · doi:10.1007/978-1-59259-987-5_2 · Cited by 5
Effects of Amyloid Beta Peptide on Neurovascular Cells
Askarova, S., Tsoy, A., Shalakhmetova, T. M., & Lee, J. C. (2013) · Central Asian Journal of Global Health · doi:10.5195/cajgh.2012.4 · Cited by 5
Vidrio, H., González-Romo, P., Álvarez, E., Alcaide, C., & Orallo, F. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.03.035 · Cited by 5
Csató, V., Pető, A., Koller, Á., Edes, I. F., Tóth, A., & Papp, Z. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103858 · Cited by 5
Activation of the Renin-Angiotensin System in Heart Failure
Kumar, R., Baker, K. M., & Pan, J. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5895-3.10009-9 · Cited by 5
Endothelial NOX1 Drives Obesity via Skeletal Muscle Mitochondrial Dysfunction
Huang, K., Huang, Y., Zhang, Y., Zhang, Y., Hatch, N. W., Freed, J. K., & Cai, H. “. (2026) · Circulation Research · doi:10.1161/circresaha.125.326768 · Cited by 4
Self-citationWu, B., Li, C., Kan, H., Zhang, Y., Rao, X., Liu, Y., & Zhao, P. (2024) · Molecules · doi:10.3390/molecules29040780 · Cited by 4
Taye, A., & Wind, S. (2010) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 4
Porphyromonas gingivalis promotes low-density lipoprotein oxidation and atherosclerosis
Kurita‐Ochiai, T., Hashizume‐Takizawa, T., Kobayashi, R., BHAWAL, U. K., Hosono, A., Kinukawa, N., & Oguchi, S. (2016) · Journal of Oral Biosciences · doi:10.1016/j.job.2016.11.001 · Cited by 4
Mohammadi, M., Khodarahmi, M., Kahroba, H., Farhangi, M. A., & Vajdi, M. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1780738 · Cited by 4
An Insight into the Potential of Flavonoids and Furanocoumarins in the Treatment of Psoriasis
Singh, A., & Srivastava, N. (2023) · Current Bioactive Compounds · doi:10.2174/1573407219666230602152010 · Cited by 4
Wang, J., Li, X., Long, J., Gao, Q., Pan, M., Yang, F., & Zhang, Y. (2024) · Metabolic Brain Disease · doi:10.1007/s11011-024-01383-y · Cited by 4
Heo, D., Lim, S., Lee, J., Lee, M. E., Cho, S., Jeong, J., Seo, M., Park, S., & Yang, J. (2019) · Scientific Reports · doi:10.1038/s41598-019-44933-6 · Cited by 4
Dunn, S. M., Hilgers, R. H. P., & Das, K. C. (2020) · Microcirculation · doi:10.1111/micc.12674 · Cited by 4
Urokinase requires NAD(P)H oxidase to transactivate the epidermal growth factor receptor
Duru, E. A., Fu, Y., & Davies, M. G. (2012) · Surgery · doi:10.1016/j.surg.2012.03.004 · Cited by 4
Kubo, M., Li, T., & Suzuki, R. (2008) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2007.11.034 · Cited by 4
sayed, L. A. E., Elattar, S., & el Tablawy, N. M. (2012) · Cited by 4
Fletcher, N. M., Abuanzeh, S., Saed, M. G., Diamond, M. P., Abu‐Soud, H. M., & Saed, G. M. (2014) · Reproductive Sciences · doi:10.1177/1933719114522524 · Cited by 3
Expanding the beneficial pleiotropic repertoire of interleukin-10
Fledderus, J. O., & Joles, J. A. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834c3041 · Cited by 3
Coto, J. G., Pereyra, E., Cavalli, F. A., Valverde, C. A., Caldiz, C. I., Maté, S. M., Yeves, A. M., & Ennis, I. L. (2024) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-024-02956-7 · Cited by 3
The scorching breath of angiotensin
Morris, B. J. (2005) · Journal of Hypertension · doi:10.1097/00004872-200501000-00008 · Cited by 3
[Prevention and treatment of hypertension and coronary heart disease].
Mendoza-González, C., Rosas, M., Lomelí, C., Lorenzo, J. A., Méndez, A., Martínez-Réding, J., Martínez‐Sánchez, C., Pastelı́n, G., Férez-Santander, S. M., & Attié, F. (2008) · PubMed · Cited by 3
Oxidase Interactions in Cardiovascular Disease
Youn, J. Y., Siu, K. L., Li, Q., Harrison, D. G., & Cai, H. “. (2014) · Springer eBooks · doi:10.1007/978-3-642-30018-9_43 · Cited by 3
Self-citationAntioxidative defense in endothelial cells: New kids on the block
Morawietz, H. (2007) · Thrombosis and Haemostasis · doi:10.1160/th06-11-0662 · Cited by 3
Reactive Oxygen Species, Oxidative Stress, and Hypertension
Touyz, R. M., Chignalia, A. Z., & Sedeek, M. H. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-600-9_15 · Cited by 2
Adeoye, A. O., Falode, J. A., Oladipupo, O. C., Obafemi, T. O., Oso, B. J., & Olaoye, I. F. (2022) · Drug and Chemical Toxicology · doi:10.1080/01480545.2022.2117372 · Cited by 2
NADPH Oxidases and Blood-Brain Barrier Dysfunction in Stroke
Kahles, T., Heumüller-Klug, S., & Brandes, R. P. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-600-9_11 · Cited by 2
Angiotensin II Blockade and Total Cardiovascular Risk
Cipollone, F., Fabio, S., Bucci, M., Cicolini, G., & Mezzetti, A. (2008) · High Blood Pressure & Cardiovascular Prevention · doi:10.2165/0151642-200815040-00004 · Cited by 2
Oxidative Stress in Human Health and Disease
ISAAC, K. (2012) · InTech eBooks · doi:10.5772/34044 · Cited by 2
Mitogen-Activated Protein Kinase and Natural Phenolic Compounds in Cardiovascular Remodeling
Alam, M. A., Uddin, S. J., & Brown, L. (2012) · Studies in natural products chemistry · doi:10.1016/b978-0-444-59530-0.00006-x · Cited by 2
ANGIOTENSIN II INDUCTION OF REGIONAL EFFECTS IN MURINE VASCULATURE
Owens, & Owens, A. P. (2009) · UKnowledge (University of Kentucky) · Cited by 2
Pereira, P. C., Pernomian, L., Côco, H., Gomes, M. S., Franco, J. J., Marchi, K. C., Hipólito, U. V., Uyemura, S. A., Tirapelli, C. R., & de Oliveira, A. M. (2016) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2016.04.008 · Cited by 2
Nitroso-Redox Crosstalk in Diabetic Cardiomyopathy
González, D. R., Treuer, A. V., & Novoa, U. (2016) · InTech eBooks · doi:10.5772/63668 · Cited by 1
Arterial'naya gipertoniya i tserebrovaskulyarnye narusheniya
Skvortsova, V. I. (2005) · Systemic Hypertension · doi:10.26442/sg28733 · Cited by 2
Catalase blockade reduces the pressor response to central cholinergic activation
Lauar, M. R., Colombari, D. S. A., Colombari, E., Paula, P. M. D., Junior, L. A. D. L., & Menani, J. V. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.09.008 · Cited by 2
Sarr, M. (2004) · OpenGrey (Institut de l'Information Scientifique et Technique) · Cited by 2
Metadata
- Authors
- Cai, H., Griendling, K. K., & Harrison, D. G.
- Affiliations
- Emory University (US)
- Corresponding author
- Harrison, David G
- Venue
- Trends in Pharmacological Sciences
- Publisher
- Elsevier BV
- Published
- 2003-09
- Volume
- 24
- Issue
- 9
- Pages
- 471-478
- ISSN
- 0165-6147 (ISSN-L)
- OpenAlex
- W2000155150
- Cited by
- 687
- References
- 84
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 13 · 2023: 3 · 2022: 9 · 2021: 12 · 2020: 18 · 2019: 11 · 2018: 13 · 2017: 10 · 2016: 26 · 2015: 25 · 2014: 32 · 2013: 35 · 2012: 47
- FWCI
- 8.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Pharmacological Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Keywords
- NADPH oxidase, reactive oxygen species, cardiovascular disease, p47phox, gp91phox, NOX2, angiotensin II, vascular smooth muscle, atherosclerosis, hypertension, therapeutic target, inflammation, vascular remodeling, angiogenesis
- MeSH terms
- Angiotensin II, Animals, Blood Vessels, Cardiovascular Agents, Cardiovascular Diseases, Enzyme Activation, Humans, Reactive Oxygen Species, NADPH Oxidases, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review