The CERAD Neuropathology Protocol and Consensus Recommendations for the Postmortem Diagnosis of Alzheimer’s Disease: A Commentary

Neuropathological stageing of Alzheimer-related changes.

Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M., Crain, B. J., Brownlee, L. M., Vogel, F. S., Hughes, J. P., Belle, G. V., Berg, L., et al. (1991) · Neurology · doi:10.1212/wnl.41.4.479 · Cited by 4,961 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assesment of Alzheimer's disease

Moms, J. C., Heyman, A., Mohs, R. C., Hughes, J. P., van Belle, G., Fillenbaum, G., Mellits, E. D., & Clark, C. (1989) · Neurology · doi:10.1212/wnl.39.9.1159 · Cited by 4,130 · see citing works

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop

McKeith, I. G., Galasko, D., Kosaka, K., Perry, E. K., Dickson, D. W., Hansen, L. A., Salmon, D. P., Lowe, J., Mirra, S. S., Byrne, E. J., et al. (1996) · Neurology · doi:10.1212/wnl.47.5.1113 · Cited by 3,960 · see citing works

Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

Fillenbaum, G., & Heyman, A. (2002) · doi:10.1002/0470846410.ch42(iii · Cited by 2,859 · see citing works

Diagnosis of Alzheimer's Disease

Khachaturian, Z. S. (1985) · Archives of Neurology · doi:10.1001/archneur.1985.04060100083029 · Cited by 2,499 · see citing works

Progressive Supranuclear Palsy

Steele, J. C. (1964) · Archives of Neurology · doi:10.1001/archneur.1964.00460160003001 · Cited by 1,930 · see citing works

The NINCDS‐ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: A clinicopathologic study of 57 cases

Tierney, M. C., Fisher, R. H., Lewis, A. J., Zorzitto, M. L., Snow, W. G., Reid, D. W., & Nieuwstraten, P. (1988) · Neurology · doi:10.1212/wnl.38.3.359 · Cited by 613 · see citing works

Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: The CERAD experience, part XV

Ellis, R. J., Olichney, J. M., Thal, L. J., Mirra, S. S., Morris, J. C., Beekly, D., & Heyman, A. (1996) · Neurology · doi:10.1212/wnl.46.6.1592 · Cited by 561 · see citing works

Making the diagnosis of Alzheimer's disease. A primer for practicing pathologists.

Mirra, S. S., Hart, M. N., & Terry, R. D. (1993) · PubMed · Cited by 412 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology Confirmation of the Clinical Diagnosis of Alzheimer's Disease

Gearing, M., Mirra, S. S., Hedreen, J. C., Sumi, S. M., Hansen, L. A., & Heyman, A. (1995) · Neurology · doi:10.1212/wnl.45.3.461 · Cited by 378 · see citing works

Relative Roles of Plaques and Tangles in the Dementia of Alzheimer's Disease: Correlations Using Three Sets of Neuropathological Criteria

Nagy, Z., Esiri, M. M., Jobst, K. A., Morris, J. H., King, E. M.-F., McDonald, B., Litchfield, S., Smith, A. D., Barnetson, L. P. D., & Smith, A. D. (1995) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000106918 · Cited by 283 · see citing works

Plaque-Only Alzheimer Disease is Usually the Lewy Body Variant, and Vice Versa

Hansen, L. A., Masliah, E., Galasko, D., & Terry, R. D. (1993) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199311000-00012 · Cited by 227 · see citing works

Corticobasal degeneration

Schneider, J. A., Watts, R. L., Gearing, M., Brewer, R. P., & Mirra, S. S. (1997) · Neurology · doi:10.1212/wnl.48.4.959 · Cited by 218 · see citing works

Interlaboratory Comparison of Neuropathology Assessments in Alzheimerʼs Disease: A Study of the Consortium to Establish a Registry for Alzheimerʼs Disease (CERAD)

MIRRA, S. S., GEARING, M., MCKEEL, D. W., CRAIN, B. J., HUGHES, J. P., BELLE, G. V., & HEYMAN, A. (1994) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199405000-00012 · Cited by 156 · see citing works

From the New Editor

Griggs, R. C. (1997) · Neurology · doi:10.1212/wnl.48.1.1 · Cited by 123 · see citing works

Progressive supranuclear palsy

Gearing, M., Olson, D. A., Watts, R. L., & Mirra, S. S. (1994) · Neurology · doi:10.1212/wnl.44.6.1015 · Cited by 120 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

Hulette, C., Mirra, S. S., Wilkinson, W. E., Heyman, A., Fillenbaum, G. G., & Clark, C. (1995) · Neurology · doi:10.1212/wnl.45.11.1991 · Cited by 98 · see citing works

Practice Guidelines for Autopsy Pathology

Hutchins, G. M., Berman, J. J., Moore, G. W., & Hanzlick, R. L. (1999) · Archives of Pathology & Laboratory Medicine · doi:10.5858/1999-123-1085-pgfap · Cited by 93 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part III. Reliability of a standardized MRI evaluation of Alzheimer's disease

Davis, P. C., Gray, L., Albert, M., Wilkinson, W. E., Hughes, J., Heyman, A., Gado, M., Kumar, A. J., Destian, S., Lee, C., et al. (1992) · Neurology · doi:10.1212/wnl.42.9.1676 · Cited by 71 · see citing works

Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease

Welsh‐Bohmer, K. A., Gearing, M., Saunders, A. M., Roses, A. D., & Mirra, S. (1997) · Annals of Neurology · doi:10.1002/ana.410420308 · Cited by 67 · see citing works

Neuropathological Diagnostic Criteria from Brain Banking

Cruz-Sánchez, F. F., Ravid, R., Cuzner, M. L., & Petito, C. K. (1996) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199605000-00012 · Cited by 42 · see citing works

Practice guidelines for autopsy pathology. Autopsy procedures for brain, spinal cord, and neuromuscular system. Autopsy Committee of the College of American Pathologists.

Powers, J. M. (1995) · PubMed · Cited by 29 · see citing works

LETTER TO THE EDITOR

Jellinger, K. A., Bancher, C., & Fischer, P. A. (1995) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199501000-00015 · Cited by 9 · see citing works

Interlaboratory comparison of neuropathology assessment in Alzheimer's disease.

Ka, J., Bancher, C., & Fischer, P. Q. (1995) · PubMed · Cited by 8 · see citing works

ALZHEIMERʼS DISEASE WITH CONCOMITANT PARKINSONʼS DISEASE CHANGES

Gearing, M., & Mirra, S. S. (1997) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199705000-00193 · Cited by 4 · see citing works

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

Nelson, P. T., Alafuzoff, I., Bigio, E. H., Bouras, C., Braak, H., Cairns, N. J., Castellani, R. J., Crain, B. J., Davies, P., Tredici, K. D., et al. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31825018f7 · Cited by 2,050 · see citing works

Primary age-related tauopathy (PART): a common pathology associated with human aging

Crary, J. F., Trojanowski, J. Q., Schneider, J. A., Abisambra, J. F., Abner, E. L., Alafuzoff, I., Arnold, S. E., Attems, J., Beach, T. G., Bigio, E. H., et al. (2014) · Acta Neuropathologica · doi:10.1007/s00401-014-1349-0 · Cited by 1,467 · see citing works

The neuropathology of probable Alzheimer disease and mild cognitive impairment

Schneider, J. A., Arvanitakis, Z., Leurgans, S. E., & Bennett, D. A. (2009) · Annals of Neurology · doi:10.1002/ana.21706 · Cited by 935 · see citing works

Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre

Toledo, J. B., Arnold, S. E., Raible, K., Brettschneider, J., Xie, S. X., Grossman, M., Monsell, S. E., Kukull, W. A., & Trojanowski, J. Q. (2013) · Brain · doi:10.1093/brain/awt188 · Cited by 849 · see citing works

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer’s disease

Georganopoulou, D. G., Chang, L., Nam, J.-M., Thaxton, C. S., Mufson, E. J., Klein, W. L., & Mirkin, C. A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409336102 · Cited by 835 · see citing works

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

Nelson, P. T., Braak, H., & Markesbery, W. R. (2009) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181919a48 · Cited by 643 · see citing works

Neuropathological changes in essential tremor: 33 cases compared with 21 controls

Louis, E. D., Faust, P. L., Vonsattel, J., Honig, L. S., Rajput, A. H., Robinson, C. A., Rajput, A. H., Pahwa, R., Lyons, K. E., Ross, G. W., et al. (2007) · Brain · doi:10.1093/brain/awm266 · Cited by 562 · see citing works

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer’s disease

Kalaria, R. N. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1571-z · Cited by 441 · see citing works

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

Pasinetti, G., & Aisen, P. (1998) · Neuroscience · doi:10.1016/s0306-4522(98)00218-8 · Cited by 457 · see citing works

Pathological correlates of dementia in a longitudinal, population‐based sample of aging

Sonnen, J. A., Larson, E. B., Crane, P. K., Haneuse, S., Li, G., Schellenberg, G. D., Craft, S., Leverenz, J. B., & Montine, T. J. (2007) · Annals of Neurology · doi:10.1002/ana.21208 · Cited by 432 · see citing works

Staging of Argyrophilic Grains: An Age-Associated Tauopathy

Saito, Y., Ruberu, N. N., Sawabe, M., Arai, T., Tanaka, N., Kakuta, Y., Yamanouchi, H., & Murayama, S. (2004) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/63.9.911 · Cited by 432 · see citing works

An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease

Nativio, R., Lan, Y., Donahue, G., Sidoli, S., Berson, A., Srinivasan, A. R., Shcherbakova, O., Amlie-Wolf, A., Nie, J., Cui, X., et al. (2020) · Nature Genetics · doi:10.1038/s41588-020-0696-0 · Cited by 380 · see citing works

Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease

Nativio, R., Donahue, G., Berson, A., Lan, Y., Amlie-Wolf, A., Tuzer, F., Toledo, J. B., Gosai, S. J., Gregory, B. D., Torres, C., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0101-9 · Cited by 363 · see citing works

Neuropathology of dementia in Parkinson's disease: A prospective, community‐based study

Aarsland, D., Perry, R., Brown, A. D., Larsen, J. O., & Ballard, C. G. (2005) · Annals of Neurology · doi:10.1002/ana.20635 · Cited by 347 · see citing works

The pathology and pathophysiology of vascular dementia

Kalaria, R. N. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.12.030 · Cited by 344 · see citing works

Clinical and pathological characterization of progressive aphasia

Knibb, J., Xuereb, J., Patterson, K., & Hodges, J. R. (2006) · Annals of Neurology · doi:10.1002/ana.20700 · Cited by 346 · see citing works

The pathological basis of semantic dementia

Davies, R. R., Hodges, J. R., Kril, J. J., Patterson, K., Halliday, G. M., & Xuereb, J. H. (2005) · Brain · doi:10.1093/brain/awh582 · Cited by 325 · see citing works

Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort: Neuritic Plaques and Neurofibrillary Tangles "Do Count" When Staging Disease Severity

Nelson, P. T., Jicha, G. A., Schmitt, F. A., Liu, H., Davis, D. G., Mendiondo, M. S., Abner, E. L., & Markesbery, W. R. (2007) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/nen.0b013e31815c5efb · Cited by 292 · see citing works

Towards defining the neuropathological substrates of vascular dementia

Kalaria, R. N., Kenny, R. A., Ballard, C. G., Perry, R., Ince, P., & Polvikoski, T. (2004) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2004.09.019 · Cited by 291 · see citing works

Atherosclerosis and AD: Analysis of data from the US National Alzheimer’s Coordinating Center

Honig, L. S., Kukull, W., & Mayeux, R. (2005) · Neurology · doi:10.1212/01.wnl.0000150886.50187.30 · Cited by 284 · see citing works

Circle of Willis Atherosclerosis Is a Risk Factor for Sporadic Alzheimer’s Disease

Roher, A. E., Esh, C. L., Kokjohn, T. A., Kalback, W. M., Luehrs, D. C., Seward, J. D., Sue, L. I., & Beach, T. G. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000095973.42032.44 · Cited by 280 · see citing works

Low sensitivity in clinical diagnoses of dementia with Lewy bodies

Nelson, P. T., Jicha, G. A., Kryscio, R. J., Abner, E. L., Schmitt, F. A., Cooper, G. E., Xu, L., Smith, C. D., & Markesbery, W. R. (2009) · Journal of Neurology · doi:10.1007/s00415-009-5324-y · Cited by 273 · see citing works

Evidence for caspase‐mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease

Chan, S. L., Griffin, W. S. T., & Mattson, M. P. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990801)57:3 · Cited by 137 · see citing works

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies

Ihara, M., Polvikoski, T. M., Hall, R., Slade, J. Y., Perry, R. H., Oakley, A. E., Englund, E. M., O'Brien, J. T., Ince, P. G., & Kalaria, R. N. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0635-8 · Cited by 242 · see citing works

Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

Li, G., Larson, E. B., Sonnen, J. A., Shofer, J. B., Petrie, E. C., Schantz, A. M., Peskind, E. R., Raskind, M. A., Breitner, J. C. S., & Montine, T. J. (2007) · Neurology · doi:10.1212/01.wnl.0000277657.95487.1c · Cited by 237 · see citing works

A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank

Toledo, J. B., Van Deerlin, V. M., Lee, E. B., Suh, E., Baek, Y., Robinson, J. L., Xie, S. X., McBride, J., Wood, E. M., Schuck, T., et al. (2014) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2013.06.003 · Cited by 234 · see citing works

Different Patterns of Cerebral Injury in Dementia With or Without Diabetes

Sonnen, J. A. (2009) · Archives of Neurology · doi:10.1001/archneurol.2008.579 · Cited by 223 · see citing works

Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects

Castaño, E. M., Roher, A. E., Esh, C. L., Kokjohn, T. A., & Beach, T. G. (2006) · Neurological Research · doi:10.1179/016164106x98035 · Cited by 201 · see citing works

Neuronal Cyclooxygenase 2 Expression in the Hippocampal Formation as a Function of the Clinical Progression of Alzheimer Disease

Ho, L., Purohit, D. P., Haroutunian, V. H., Luterman, J. D., Willis, F., Näslund, J., Buxbaum, J. D., Mohs, R. C., Aisen, P. S. S., & Pasinetti, G. M. (2001) · Archives of Neurology · doi:10.1001/archneur.58.3.487 · Cited by 196 · see citing works

Silver diagnosis in neuropathology: principles, practice and revised interpretation

Uchihara, T. (2007) · Acta Neuropathologica · doi:10.1007/s00401-007-0200-2 · Cited by 197 · see citing works

Cytokine Gene Expression as a Function of the Clinical Progression of Alzheimer Disease Dementia

Luterman, J. D., Haroutunian, V., Yemul, S., Ho, L., Purohit, D., Aisen, P. S., Mohs, R., & Pasinetti, G. M. (2000) · Archives of Neurology · doi:10.1001/archneur.57.8.1153 · Cited by 192 · see citing works

Pathological α-synuclein distribution in subjects with coincident Alzheimer’s and Lewy body pathology

Toledo, J. B., Gopal, P., Raible, K., Irwin, D. J., Brettschneider, J., Sedor, S., Waits, K., Boluda, S., Grossman, M., Van Deerlin, V. M., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-015-1526-9 · Cited by 184 · see citing works

The <i>APOE</i> ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients

Hultman, K., Strickland, S., & Norris, E. H. (2013) · Journal of Cerebral Blood Flow &amp; Metabolism · doi:10.1038/jcbfm.2013.76 · Cited by 183 · see citing works

Morphological and Pathological Evolution of the Brain Microcirculation in Aging and Alzheimer’s Disease

Hunter, J. M., Kwan, J., Malek‐Ahmadi, M. H., Maarouf, C. L., Kokjohn, T. A., Belden, C. M., Sabbagh, M. N., Beach, T. G., & Roher, A. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036893 · Cited by 175 · see citing works

Increased Neurofibrillary Tangles in Patients With Alzheimer Disease With Comorbid Depression

Rapp, M. A., Beeri, M. S., Purohit, D. P., Perl, D. P., Haroutunian, V. H., & Sano, M. C. (2008) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31816029ec · Cited by 178 · see citing works

Purkinje cell axonal anatomy: quantifying morphometric changes in essential tremor versus control brains

Babij, R., Lee, M., Cortes, E. P., Vonsattel, J., Faust, P. L., & Louis, E. D. (2013) · Brain · doi:10.1093/brain/awt238 · Cited by 175 · see citing works

Cholesterol Accumulates in Senile plaques of Alzheimer Disease patients and in Transgenic APPswMice

Mori, T., Paris, D., Town, T., Rojiani, A. M., Sparks, D. L., DelleDonne, A., Crawford, F., Abdullah, L. I., Humphrey, J., Dickson, D. W., et al. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.8.778 · Cited by 175 · see citing works

Late-onset vs nonmendelian early-onset Alzheimer disease

Reitz, C., Rogaeva, E. A., & Beecham, G. W. (2020) · Neurology Genetics · doi:10.1212/nxg.0000000000000512 · Cited by 171 · see citing works

Clinical and multimodal biomarker correlates of ADNI neuropathological findings

Toledo, J. B., Cairns, N. J., Da, X., Chen, K., Carter, D. R., Fleisher, A., Householder, E., Ayutyanont, N., Roontiva, A., Bauer, R. J., III, et al. (2013) · Acta Neuropathologica Communications · doi:10.1186/2051-5960-1-65 · Cited by 165 · see citing works

A Population-Based Clinicopathological Study in the Oldest-Old: The 90+ Study

M. Corrada, M., J. Berlau, D., & H. Kawas, C. (2012) · Current Alzheimer Research · doi:10.2174/156720512801322537 · Cited by 162 · see citing works

Atherosclerosis, vascular amyloidosis and brain hypoperfusion in the pathogenesis of sporadic Alzheimer's disease

Kalback, W. M., Esh, C. L., Castaño, E. M., Rahman, A., Kokjohn, T. A., Luehrs, D. C., Sue, L. I., Cisneros, R., Gerber, F., Richardson, C., et al. (2004) · Neurological Research · doi:10.1179/016164104225017668 · Cited by 160 · see citing works

A canine model of human aging and Alzheimer's disease

Head, E. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.03.016 · Cited by 160 · see citing works

“New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)

Nelson, P. T., Trojanowski, J. Q., Abner, E. L., Al-Janabi, O. M., Jicha, G. A., Schmitt, F. A., Smith, C. D., Fardo, D. W., Wang, W.-X., Kryscio, R. J., et al. (2016) · Journal of Neuropathology &amp; Experimental Neurology · doi:10.1093/jnen/nlw033 · Cited by 158 · see citing works

"Hairy Baskets” Associated With Degenerative Purkinje Cell Changes in Essential Tremor

Erickson-Davis, C. R., Faust, P. L., Vonsattel, J., Gupta, S., Honig, L. S., & Louis, E. D. (2010) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181d1ad04 · Cited by 153 · see citing works

Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease

Brooks, W. M., Lynch, P. J., Ingle, C. C., Hatton, A., Emson, P. C., Faull, R. L. M., & Starkey, M. (2006) · Brain Research · doi:10.1016/j.brainres.2006.09.106 · Cited by 148 · see citing works

Atherosclerosis of Cerebral Arteries in Alzheimer Disease

Roher, A. E., Esh, C. L., Rahman, A., Kokjohn, T. A., & Beach, T. G. (2004) · Stroke · doi:10.1161/01.str.0000143317.70478.b3 · Cited by 146 · see citing works

Is the pathology of corticobasal syndrome predictable in life?

Shelley, B. P., Hodges, J. R., Kipps, C., Xuereb, J. H., & Bak, T. H. (2009) · Movement Disorders · doi:10.1002/mds.22558 · Cited by 139 · see citing works

Abnormal climbing fibre-Purkinje cell synaptic connections in the essential tremor cerebellum

Lin, C.-Y. R., Louis, E. D., Faust, P. L., Koeppen, A. H., Vonsattel, J., & Kuo, S. (2014) · Brain · doi:10.1093/brain/awu281 · Cited by 136 · see citing works

Physicochemical characteristics of soluble oligomeric Aβand their pathologic role in Alzheimer's disease

Watson, D., Castaño, E., Kokjohn, T. A., Kuo, Y., Lyubchenko, Y. L., Pinsky, D. J., Connolly, E. S., Esh, C. L., Luehrs, D. C., Stine, W. B., et al. (2005) · Neurological Research · doi:10.1179/016164105x49436 · Cited by 129 · see citing works

Reduced Purkinje cell dendritic arborization and loss of dendritic spines in essential tremor

Louis, E. D., Lee, M., Babij, R., Ma, K., Cortes, E. P., Vonsattel, J., & Faust, P. L. (2014) · Brain · doi:10.1093/brain/awu314 · Cited by 128 · see citing works

Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment

Barone, E., Domenico, F. D., Rukhsana Sultana, A., Coccia, R., Mancuso, C., Marzia Perluigi, A., & Butterfield, D. A. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.03.020 · Cited by 123 · see citing works

Is synaptic loss a unique hallmark of Alzheimer’s disease?

Scheff, S. W., Neltner, J. H., & Nelson, P. T. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.12.028 · Cited by 118 · see citing works

Brains With Medial Temporal Lobe Neurofibrillary Tangles But No Neuritic Amyloid Plaques Are a Diagnostic Dilemma But May Have Pathogenetic Aspects Distinct From Alzheimer Disease

Nelson, P. T., Abner, E. L., Schmitt, F. A., Kryscio, R. J., Jicha, G. A., Santacruz, K., Smith, C. D., Patel, E., & Markesbery, W. R. (2009) · Journal of Neuropathology &amp; Experimental Neurology · doi:10.1097/nen.0b013e3181aacbe9 · Cited by 115 · see citing works

Population-based neuropathological studies of dementia: design, methods and areas of investigation – a systematic review

ZACCAI, J. H., Ince, P. G., & Brayne, C. (2006) · BMC Neurology · doi:10.1186/1471-2377-6-2 · Cited by 111 · see citing works

Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia

Pasinetti, G. M. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1176 · Cited by 111 · see citing works

Beyond mild cognitive impairment: vascular cognitive impairment, no dementia (VCIND)

Stephan, B. C. M., Matthews, F. E., Khaw, K., Dufouil, C., & Brayne, C. (2009) · Alzheimer s Research & Therapy · doi:10.1186/alzrt4 · Cited by 107 · see citing works

Brain pathologies in extreme old age

Neltner, J. H., Abner, E. L., Jicha, G. A., Schmitt, F. A., Patel, E., Poon, L. W., Marla, G., Green, R. C., Davey, A., Johnson, M. A., et al. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.10.009 · Cited by 106 · see citing works

Concurrent Alzheimer's pathology in patients with clinical normal pressure hydrocephalus: correlation of high-volume lumbar puncture results, cortical brain biopsies, and outcomes.

Pomeraniec, I. J., Bond, A. E., Lopes, M. B., & Jane, J. (2016) · Journal of Neurosurgery · doi:10.3171/2015.2.jns142318 · Cited by 94 · see citing works

Increased number of heterotopic Purkinje cells in essential tremor

Kuo, S., Erickson-Davis, C. R., Gillman, A., Faust, P. L., Vonsattel, J., & Louis, E. D. (2010) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2010.213330 · Cited by 103 · see citing works

Altered expression of a-type but not b-type synapsin isoform in the brain of patients at high risk for Alzheimer's disease assessed by DNA microarray technique

Ho, L. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01753-5 · Cited by 103 · see citing works

Torpedoes in Parkinson's disease, Alzheimer's disease, essential tremor, and control brains

Louis, E. D., Faust, P. L., Vonsattel, J., Honig, L. S., Rajput, A. H., Rajput, A. H., Pahwa, R., Lyons, K. E., Ross, W. G., Elble, R. J., et al. (2009) · Movement Disorders · doi:10.1002/mds.22567 · Cited by 101 · see citing works

Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer’s disease pathology

Scheff, S. W., Ansari, M. A., & Mufson, E. J. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.02.030 · Cited by 100 · see citing works

Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies

Nelson, P. T., Kryscio, R. J., Jicha, G. A., Abner, E. L., Schmitt, F. A., Xu, L. O., Cooper, G., Smith, C. D., & Markesbery, W. R. (2009) · Neurology · doi:10.1212/wnl.0b013e3181bacf9e · Cited by 99 · see citing works

Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

Latimer, C. S., Burke, B. T., Liachko, N. F., Currey, H. N., Kilgore, M. D., Gibbons, L. E., Henriksen, J. C., Darvas, M., Domoto‐Reilly, K., Jayadev, S., et al. (2019) · Acta Neuropathologica Communications · doi:10.1186/s40478-019-0743-1 · Cited by 99 · see citing works

Purkinje cell loss in essential tremor: Random sampling quantification and nearest neighbor analysis

Choe, M., Cortes, E. P., Vonsattel, J., Kuo, S., Faust, P. L., & Louis, E. D. (2016) · Movement Disorders · doi:10.1002/mds.26490 · Cited by 91 · see citing works

Hippocampal ProNGF Signaling Pathways and β-Amyloid Levels in Mild Cognitive Impairment and Alzheimer Disease

Mufson, E. J., He, B., Nadeem, M., Perez, S. E., Counts, S., Leurgans, S. E., Fritz, J. J., Lah, J. J., Ginsberg, S. D., Wuu, J., et al. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e318272caab · Cited by 90 · see citing works

Isofurans, but not F2‐isoprostanes, are increased in the substantia nigra of patients with Parkinson's disease and with dementia with Lewy body disease

Fessel, J. P., Hulette, C., Powell, S. Z.-E., Roberts, L. J., & Zhang, J. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01709.x · Cited by 90 · see citing works

The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients

Collins, M. A., Riascos, D., Kovalik, T., An, J., Krupa, K., Krupa, K., Hood, B. L., Conrads, T. P., Renton, A. E., Traynor, B. J., et al. (2012) · Acta Neuropathologica · doi:10.1007/s00401-012-1045-x · Cited by 89 · see citing works

Climbing fiber-Purkinje cell synaptic pathology in tremor and cerebellar degenerative diseases

Kuo, S., Lin, C.-Y. R., Wang, J., Sims, P. A., Pan, M., Liou, J.-Y., Lee, D., Tate, W. J., Kelly, G. C., Louis, E. D., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1626-1 · Cited by 89 · see citing works

Rest tremor in advanced essential tremor: a post-mortem study of nine cases

Louis, E. D., Asabere, N., Agnew, A., Moskowitz, C. B., Lawton, A., Cortes, E. P., Faust, P. L., & Vonsattel, J. (2010) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2010.215681 · Cited by 88 · see citing works

Neuropathologic assessment of participants in two multi‐center longitudinal observational studies: The <scp>A</scp>lzheimer <scp>D</scp>isease <scp>N</scp>euroimaging <scp>I</scp>nitiative (<scp>ADNI</scp>) and the <scp>D</scp>ominantly <scp>I</scp>nherited <scp>A</scp>lzheimer <scp>N</scp>etwork (<scp>DIAN</scp>)

Cairns, N. J., Perrin, R. J., Franklin, E. E., Carter, D., Vincent, B., Xie, M., Bateman, R. J., Benzinger, T., Friedrichsen, K., Brooks, W. S., et al. (2015) · Neuropathology · doi:10.1111/neup.12205 · Cited by 86 · see citing works

Chromogranin peptides in Alzheimer's disease

Lechner, T., Adlassnig, C., Humpel, C., Kaufmann, W. A., Maier, H., Kramer-Reinstadler, K., Hinterhoelzl, J., Mahata, S. K., Jellinger, K. A., & Marksteiner, J. (2003) · Experimental Gerontology · doi:10.1016/j.exger.2003.09.018 · Cited by 86 · see citing works

Identification of Glutathione S-Transferase Pi as a Protein Involved in Parkinson Disease Progression

Shi, M. Y., Bradner, J. M., Bammler, T. K., Eaton, D. L., Zhang, J., Ye, Z., Wilson, A. M., Montine, T. J., Pan, C., & Zhang, J. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.081019 · Cited by 85 · see citing works

Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau

Kuo, S., Tang, G., Louis, E. D., Ma, K., Babji, R., Balatbat, M., Cortes, E. P., Vonsattel, J., Yamamoto, A., Sulzer, D. L., et al. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1108-7 · Cited by 83 · see citing works

Digital Pathology and Image Analysis for Robust High-Throughput Quantitative Assessment of Alzheimer Disease Neuropathologic Changes

Neltner, J. H., Abner, E. L., Schmitt, F. A., Denison, S. K., Anderson, S., Patel, E., & Nelson, P. T. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3182768de4 · Cited by 83 · see citing works

Mortalin: A Protein Associated With Progression of Parkinson Disease?

Shi, M. Y., Jin, J., Wang, Y., Beyer, R. P., Kitsou, E., Albin, R. L., Gearing, M., Pan, C., & Zhang, J. (2008) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e318163354a · Cited by 82 · see citing works

Increased number of Purkinje cell dendritic swellings in essential tremor

Yu, M., Ma, K., Faust, P. L., Honig, L. S., Cortés, E., Vonsattel, J., & Louis, E. D. (2011) · European Journal of Neurology · doi:10.1111/j.1468-1331.2011.03598.x · Cited by 82 · see citing works

Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging

Maarouf, C. L., Daugs, I. D., Kokjohn, T. A., Walker, D. G., Hunter, J. M., Kruchowsky, J., Woltjer, R. L., Kaye, J. A., Castaño, E. M., Sabbagh, M. N., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027291 · Cited by 80 · see citing works

The autopsy as an outcome and performance measure.

Shojania, K. G., Burton, E. C., McDonald, K. M., & Goldman, L. (2002) · PubMed Central · Cited by 78 · see citing works

Quantification of cerebellar hemispheric purkinje cell linear density: 32 ET cases versus 16 controls

Louis, E. D., Babij, R., Lee, M., Cortes, E. P., & Vonsattel, J. (2013) · Movement Disorders · doi:10.1002/mds.25629 · Cited by 78 · see citing works

First Evidence for Helical Transitions in Supercoiled DNA by Amyloid β Peptide (1-42) and Aluminum: A New Insight in Understanding Alzheimer's Disease

Hegde, M. L., Anitha, S., Latha, K. S., Mustak, M. S., Stein, R., Ravid, R., & Rao, K. S. J. (2004) · Journal of Molecular Neuroscience · doi:10.1385/jmn:22:1-2:19 · Cited by 77 · see citing works

Contextualizing the pathology in the essential tremor cerebellar cortex: a patholog-omics approach

Louis, E. D., Kerridge, C. A., Chatterjee, D., Martuscello, R. T., Diaz, D. T., Koeppen, A. H., Kuo, S., Vonsattel, J., Sims, P. A., & Faust, P. L. (2019) · Acta Neuropathologica · doi:10.1007/s00401-019-02043-7 · Cited by 76 · see citing works

Patient Dependence and Longitudinal Changes in Costs of Care in Alzheimer’s Disease

Zhu, C. W., Leibman, C. W., McLaughlin, T. P., Zbrozek, A. S., Scarmeas, N., Albert, M., Brandt, J., Blacker, D., Sano, M. C., & Stern, Y. (2008) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000164797 · Cited by 73 · see citing works

Older onset essential tremor: More rapid progression and more degenerative pathology

Louis, E. D., Faust, P. L., Vonsattel, J., Honig, L. S., Henchcliffe, C., Pahwa, R., Lyons, K. E., Rios, E., Erickson-Davis, C. R., Moskowitz, C. B., et al. (2009) · Movement Disorders · doi:10.1002/mds.22570 · Cited by 73 · see citing works

Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly

Malek-Ahmadi, M., Perez, S. E., Chen, K., & Mufson, E. J. (2016) · Journal of Alzheimer’s Disease · doi:10.3233/jad-160365 · Cited by 73 · see citing works

Torpedoes in the Cerebellar Vermis in Essential Tremor Cases vs. Controls

Louis, E. D., Faust, P. L., Ma, K. J., Yu, M., Cortes, E. P., & Vonsattel, J. (2011) · The Cerebellum · doi:10.1007/s12311-011-0291-0 · Cited by 72 · see citing works

Neuropathology in the Adult Changes in Thought Study: A Review

Sonnen, J. A., Larson, E. B., Haneuse, S., Woltjer, R. L., Li, G., Crane, P. K., Craft, S., & Montine, T. J. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1180 · Cited by 69 · see citing works

Reassessment of Risk Genotypes (GRN,TMEM106B, andABCC9Variants) Associated With Hippocampal Sclerosis of Aging Pathology

Nelson, P. T., Wang, W., Partch, A. B., Monsell, S. E., Valladares, O., Ellingson, S. R., Wilfred, B. R., Naj, A. C., Wang, L.-S., Kukull, W. A., et al. (2014) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0000000000000151 · Cited by 68 · see citing works

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy

Walker, J. M., Richardson, T. E., Farrell, K. W., Iida, M. A., Foong, C., Shang, P., Attems, J., Ayalon, G., Beach, T. G., Bigio, E. H., et al. (2020) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlaa153 · Cited by 69 · see citing works

Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain

Butterfield, D. A., Barone, E., Domenico, F. D., Cenini, G., Rukhsana Sultana, A., Murphy, M. P., Mancuso, C., & Head, E. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711001118 · Cited by 67 · see citing works

HDAC 2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease

Mahady, L. J., Nadeem, M., Malek‐Ahmadi, M. H., Chen, K., Perez, S. E., & Mufson, E. J. (2018) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12518 · Cited by 64 · see citing works

The inferior olivary nucleus: A postmortem study of essential tremor cases versus controls

Louis, E. D., Babij, R., Cortes, E. P., Vonsattel, J., & Faust, P. L. (2013) · Movement Disorders · doi:10.1002/mds.25400 · Cited by 66 · see citing works

African ancestry protects against Alzheimer's disease-related neuropathology

the Brazilian Aging Brain Study Group, Schlesinger, D., Grinberg, L. T., Alba, J. G., Naslavsky, M. S., Licínio, L., Farfel, J. M., Suemoto, C. K., Ferretti‐Rebustini, R. E. D. L., Leite, R. E. P., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.136 · Cited by 65 · see citing works

The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain

Fluteau, A., Ince, P. G., Minett, T., Matthews, F. E., Brayne, C., Garwood, C. J., Ratcliffe, L. E., Morgan, S., Heath, P. R., Shaw, P. J., et al. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.10.001 · Cited by 66 · see citing works

Small‐vessel disease in patients with Parkinson's disease: A clinicopathological study

Schwartz, R. S., Halliday, G. M., Cordato, D. J., & Kril, J. J. (2012) · Movement Disorders · doi:10.1002/mds.25112 · Cited by 62 · see citing works

The Neuropathology of Vascular Disease in the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)

Richardson, K., Stephan, B. C. M., Ince, P. G., Brayne, C., & Matthews, F. E. (2012) · Current Alzheimer Research · doi:10.2174/156720512801322654 · Cited by 61 · see citing works

The Effects of Patient Function and Dependence on Costs of Care in Alzheimer's Disease

Zhu, C. W., Leibman, C. W., McLaughlin, T. P., Scarmeas, N., Albert, M., Brandt, J., Blacker, D., Sano, M., & Stern, Y. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01798.x · Cited by 61 · see citing works

Frontal Cortex Epigenetic Dysregulation During the Progression of Alzheimer’s Disease

Mahady, L. J., Nadeem, M., Malek‐Ahmadi, M. H., Chen, K., Perez, S. E., & Mufson, E. J. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-171032 · Cited by 60 · see citing works

Histopathology of the cerebellar cortex in essential tremor and other neurodegenerative motor disorders: comparative analysis of 320 brains

Louis, E. D., Martuscello, R. T., Gionco, J. T., Hartstone, W. G., Musacchio, J. B., Portenti, M., McCreary, M., Kuo, S., Vonsattel, J., & Faust, P. L. (2023) · Acta Neuropathologica · doi:10.1007/s00401-022-02535-z · Cited by 59 · see citing works

Adult Changes in Thought Study: Dementia is an Individually Varying Convergent Syndrome with Prevalent Clinically Silent Diseases that may be Modified by Some Commonly Used Therapeutics

Montine, T. J., Sonnen, J. A., Montine, K. S., Crane, P. K., & Larson, E. B. (2012) · Current Alzheimer Research · doi:10.2174/156720512801322555 · Cited by 56 · see citing works

Neuropathological Assessment of Alzheimer’s Disease: The Experience of the Consortium to Establish a Registry for Alzheimer’s Disease

Mirra, S. S. (1997) · International Psychogeriatrics · doi:10.1017/s1041610297004985 · Cited by 39 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M., Crain, B. J., Brownlee, L. M., Vogel, F. S., Hughes, J. P., Belle, G. V., Berg, L., et al. (1991) · Neurology · doi:10.1212/wnl.41.4.479 · Cited by 4,961 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology Confirmation of the Clinical Diagnosis of Alzheimer's Disease

Gearing, M., Mirra, S. S., Hedreen, J. C., Sumi, S. M., Hansen, L. A., & Heyman, A. (1995) · Neurology · doi:10.1212/wnl.45.3.461 · Cited by 378 · see citing works

Diagnostic Criteria for the Neuropathological Assessment of Alzheimer’s disease: Current Status and Major Issues

Wı́sniewski, H. M., & Silverman, W. P. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00068-7 · Cited by 22 · see citing works

Commentary on the Consensus Recommendations for the Post Mortem Diagnosis of Alzheimer’s Disease

McLean, C., Beyreuther, K. T., & Masters, C. L. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00061-4 · Cited by 8 · see citing works