Cited by 1,088Stress Responses and CortisolNeuroendocrine regulation and behaviorChild and Adolescent Psychosocial and Emotional Development

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Social regulation of the cortisol levels in early human development

Gunnar, Megan R., Donzella, Bonny·2002·Psychoneuroendocrinology

DOI 10.1016/s0306-4530(01)00045-2

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Abstract

Other papers in this special edition provide evidence to implicate activity of the limbic hypothalamic-pituitary-adrenocortical (L-HPA) system in the etiology of drug and alcohol abuse. Furthermore, studies in rodents and primates suggest that responsivity and regulation of this system later in life may be shaped by social experiences during early development. Cortisol is the major hormonal product of the L-HPA system in humans. Although it provides only a partial understanding of the activity of this neuroendocrine axis, its regulation may bear importantly on human growth and development. We review developmental studies of cortisol and behavior in human children, birth to approximately 5 years of age. We describe the development of social buffering of cortisol responses that produces a functional analogue of the rodent stress hyporesponsive period by the time children are about 12 months of age. We further describe the sensitivity of cortisol activity to variations in care quality among infants and toddlers, along with evidence that children with negative emotional temperaments may be most likely to exhibit elevations in cortisol under conditions of less than optimal care. Finally, the few studies of cortisol activity under conditions of neglectful and abusive care of young children are considered, noting that these often have yielded evidence of reduced rather than increased cortisol levels.

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Peer Interactions, Relationships, and Groups
Rubin, K. H., Bukowski, W. M., & Parker, J. G. (2007) · Handbook of Child Psychology · doi:10.1002/9780470147658.chpsy0310 · Cited by 2,755
Brain corticosteroid receptor balance in health and disease
de Kloet, E. R., Vreugdenhil, E., Oitzl, M. S., & Joëls, M. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.3.0331 · Cited by 2,614
Brain corticosteroid receptor balance in health and disease
de Kloet, E. R. (1998) · Endocrine Reviews · doi:10.1210/er.19.3.269 · Cited by 2,614
The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders
Heim, C., Ehlert, U., & Hellhammer, D. H. (2000) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(99)00035-9 · Cited by 1,688
Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat
Caldji, C., Tannenbaum, B., Sharma, S., Francis, D., Plotsky, P. M., & Meaney, M. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.9.5335 · Cited by 1,437
The Physiology and Psychology of Behavioral Inhibition in Children
Kagan, J., Reznick, J. S., & Snidman, N. C. (1987) · Child Development · doi:10.2307/1130685 · Cited by 1,368
Low cortisol and a flattening of expected daytime rhythm: Potential indices of risk in human development
GUNNAR, M. R., & VAZQUEZ, D. M. (2001) · Development and Psychopathology · doi:10.1017/s0954579401003066 · Cited by 900
Self-citation
Mechanisms of stress: A dynamic overview of hormonal and behavioral homeostasis
Johnson, E. O., Kamilaris, T. C., Chrousos, G. P., & Gold, P. W. (1992) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80175-7 · Cited by 899
Developmental traumatology part I: biological stress systems∗∗See accompanying Editorial, in this issue.
De Bellis, M. D., Baum, A. S., Birmaher, B., Keshavan, M. S., Eccard, C. H., Boring, A. M., Jenkins, F. J., & Ryan, N. D. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00044-x · Cited by 741
Behavioral Inhibition and Stress Reactivity: The Moderating Role of Attachment Security
Nachmias, M., Gunnar, M., Mangelsdorf, S., Parritz, R. H., & Buss, K. (1996) · Child Development · doi:10.2307/1131829 · Cited by 730
Self-citation

Show all 88 references

Research works printed but not linked: 13

Ames, E.W., 1990. Spitz revised: a trip to Romanian “orphanages”. Canadian Psychological Association Developmental Psychology Section Newsletter, 9(2), 8–11.
Alwin, J., Goldsmith, S., Lane, S.K., 2000. Salivary cortisol in infants at daycare and at home. Poster presented at the International Conference on Infant Studies, Brighton, England.
Bruce, J., Kroupina, M., Parker, S., Gunnar, M.R., 2000. The relationships between cortisol patterns, growth retardation, and developmental delay in post-institutionalized children. Poster presented at the International Conference on Infant Studies, Brighton, England.
Carlson, 1995, Effects of social deprivation on cortisol regulation in institutionalized Romanian infants, Soc. Neurosci. Abstr., 21, 524
Gilles, E.E., Berntson, G.G., Zipf, W.B., Gunnar, M., 2000. Neglect is associated with a blunting of behavioral and biological stress responses in human infants. Paper presented at the Conference on Infant Studies, Brighton, England.
Hessl, D., Dawson, G., Frey, K., Panagiotides, H., Self, H., Yamada, E., Osterling, J., 1998. A longitudinal study of children of depressed mothers: psychobiological findings related to stress. In: Hann, D.M., Huffman, L.C., Lederhendler, K.K., Minecke, D. (Eds.), Advancing Research on Developmental Plasticity: Integrating the Behavioral Sciences and the Neurosciences of Mental Health. National Institutes of Mental Health, Bethesda, MD, p. 256.
Jacobson, 1994, Differences in cortisol levels in infants exposed prenatally to alcohol and cocaine, Infant Behav. Dev., 17, 722
Kaufman, 1999, Neurobiological correlates of child abuse, Biol. Psychiat., 45, 1235
Lane, S.K., 1999. Daily cortisol pattern, daytime naps, and temperament in infants and preschoolers. Unpublished Undergraduate Honor's Thesis, University of Minnesota, Minneapolis, MN.
Lane, S.K., Donzella, B., Boxer, J., Gunnar, M.R., July, 2000. Cortisol levels in toddlers at full-day childcare: comparisons with home cortisol and temperament. Paper presented at the International Conference on Infant Studies, Brighton, England.
Schieche, M., Spangler, G., 2000. The moderating role of maternal sensitivity and attachment security for biobehavioral organization in infants and toddlers. Paper presented at the International Conference on Infant Studies, Brighton, England.
Vazquez, D.M., Watson, S.J., Lopez, J.F., 2000. Failure to terminate stress responses in children with psychosocial dwarfism: a mechanism for growth failure. Paper presented at the International Conference on Infant Studies, Brighton, England.
Watamura, S.E., Sebanc, A.M., Gunnar, M.R., 2001. Naptime at childcare: Effects on salivary cortisol levels. Dev. Psychobio. In press.

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Buttner, A. P. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.029 · Cited by 71
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Luecken, L. J., Kraft, A., & Hagan, M. J. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.12.007 · Cited by 66
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Thayer, Z. M., & Kuzawa, C. W. (2014) · American Journal of Human Biology · doi:10.1002/ajhb.22532 · Cited by 66
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de Weerth, C., & van Geert, P. L. C. (2002) · Infant Behavior and Development · doi:10.1016/s0163-6383(02)00141-8 · Cited by 66
Trajectories of maternal depressive symptoms over her child's life span: Relation to adrenocortical, cardiovascular, and emotional functioning in children
Gump, B. B., Reihman, J., Stewart, P., Lonky, E., Darvill, T., Granger, D. A., & Matthews, K. A. (2009) · Development and Psychopathology · doi:10.1017/s0954579409000133 · Cited by 68
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Salivary Cortisol and Behavioral State Responses of Healthy Newborn Infants to Tactile-Only and Multisensory Interventions
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Interaction between 5-HTTLPR and BDNF Val66Met polymorphisms on HPA axis reactivity in preschoolers
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Self-citation
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Sarkar, T., Patro, N., & Patro, I. K. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.02.005 · Cited by 64
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Tarullo, A., Tuladhar, C. T., Kao, K., Drury, E., & Meyer, J. S. (2020) · Development and Psychopathology · doi:10.1017/s0954579420001315 · Cited by 52
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Crockett, E. E., Holmes, B., Granger, D. A., & Lyons‐Ruth, K. (2013) · Infancy · doi:10.1111/infa.12015 · Cited by 63
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Pendry, P., Smith, A. N., & Roeter, S. M. (2014) · Human-animal interaction bulletin · doi:10.1079/hai.2014.0003 · Cited by 64
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Enthoven, L., Oitzl, M. S., Koning, N. R., van der Mark, M. H., & de Kloet, E. R. (2008) · Endocrinology · doi:10.1210/en.2008-0238 · Cited by 60
Neuroticism and extraversion in relation to physiological stress reactivity during adolescence
Evans, B. E., Stam, J. V., Huizink, A. C., Willemen, A. M., Westenberg, P. M., Branje, S., Meeus, W., Koot, H. M., & van Lier, P. A. C. (2016) · Biological Psychology · doi:10.1016/j.biopsycho.2016.03.002 · Cited by 63
Gene expression profiling following maternal deprivation: Involvement of the brain renin-angiotensin system
Liebl, C. (2009) · Frontiers in Molecular Neuroscience · doi:10.3389/neuro.02.001.2009 · Cited by 60
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Theodoridou, D., Christodoulides, P., Zakopoulou, V., & Syrrou, M. (2021) · Brain Sciences · doi:10.3390/brainsci11060782 · Cited by 64
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Pillhofer, M., Spangler, G., Bovenschen, I., Künster, A. K., Gabler, S., Fallon, B., Fegert, J. M., & Ziegenhain, U. (2014) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2014.07.007 · Cited by 59
Normative salivary cortisol values and responsivity in children
McCarthy, A. M., Hanrahan, K., Kleiber, C., Zimmerman, M. B., Lutgendorf, S. K., & Tsalikian, E. (2009) · Applied Nursing Research · doi:10.1016/j.apnr.2007.04.009 · Cited by 61
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Kirsch, D. E., Nemeroff, C. B., & Lippard, E. (2020) · Adversity and Resilience Science · doi:10.1007/s42844-020-00005-7 · Cited by 61

Authors: Gunnar, M. R., & Donzella, B.
Affiliations: University of Minnesota (US)
Corresponding author: Gunnar, Megan R.
ORCID: Gunnar, Megan R.
Donzella, Bonny
Venue: Psychoneuroendocrinology
Publisher: Elsevier BV
Published: 2002-01
Volume: 27
Issue: 1-2
Pages: 199-220
ISSN: 0306-4530 (ISSN-L)
DOI: 10.1016/s0306-4530(01)00045-2
OpenAlex: W2158279716
Cited by: 1,088
References: 88
Citations by year: 2026: 21 · 2025: 29 · 2024: 39 · 2023: 41 · 2022: 35 · 2021: 73 · 2020: 53 · 2019: 48 · 2018: 52 · 2017: 54 · 2016: 64 · 2015: 66 · 2014: 62 · 2013: 73 · 2012: 54
FWCI: 7.84
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Psychoneuroendocrinology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords: cortisol, hypothalamic-pituitary-adrenal axis, social buffering, early childhood development, emotional temperament, stress hyporesponsive period, child neglect, child abuse, neuroendocrine regulation
MeSH terms: Adolescent, Child, Child Development, Child, Preschool, Female, Humans, Hydrocortisone, Infant, Male, Social Environment

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Social regulation of the cortisol levels in early human development

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