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Alpha tocopherol supplementation decreases serum C-reactive protein and monocyte interleukin-6 levels in normal volunteers and type 2 diabetic patients
Abstract
Type 2 diabetic subjects have an increased propensity to premature atherosclerosis. Alpha tocopherol (AT), a potent antioxidant, has several anti-atherogenic effects. There is scanty data on AT supplementation on inflammation in Type 2 diabetic subjects. The aim of the study was to test the effect of RRR-AT supplementation (1200 IU/d) on plasma C-reactive protein (CRP) and interleukin-6 (IL-6) release from activated monocyte in Type 2 diabetic patients with and without macrovascular complications compared to matched controls. The volunteers comprised Type 2 diabetic subjects with macrovascular disease (DM2-MV, n = 23), Type 2 diabetic subjects without macrovascular complications (DM2, n = 24), and matched controls (C, n = 25). Plasma high sensitive CRP (Hs-CRP) and Monocyte IL-6 were assayed at baseline, following 3 months of supplementation and following a 2 month washout phase. DM2-MV subjects have elevated HsCRP and monocyte IL-6 compared to controls. AT supplementation significantly lowered levels of C-reactive protein and monocyte interleukin-6 in all three groups. In conclusion, AT therapy decreases inflammation in diabetic patients and controls and could be an adjunctive therapy in the prevention of atherosclerosis.
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“Increased consumption of dairy products has been shown to have beneficial effects on plasma CRP and adiponectin concentrations in obese subjects (683) .”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [683]
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Ridker, P. M., Buring, J. E., Shih, J., Matias, M., & Hennekens, C. H. (1998) · Circulation · doi:10.1161/01.cir.98.8.731 · Cited by 1,642
The Pathophysiologic Roles of Interleukin-6 in Human Disease
Papanicolaou, D. A., Wilder, R. L., Manolagas, S. C., & Chrousos, G. P. (1998) · Annals of Internal Medicine · doi:10.7326/0003-4819-128-2-199801150-00009 · Cited by 1,146
Is Type II diabetes mellitus a disease of the innate immune system?
Pickup, J. C., & Crook, M. A. (1998) · Diabetologia · doi:10.1007/s001250051058 · Cited by 1,042
Body mass index, diabetes, and C-reactive protein among U.S. adults.
Ford, E. S. (1999) · Diabetes Care · doi:10.2337/diacare.22.12.1971 · Cited by 642
Pryor, W. A. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00224-5 · Cited by 450
Novel Inflammatory Markers of Coronary Risk
Libby, P., & Ridker, P. M. (1999) · Circulation · doi:10.1161/01.cir.100.11.1148 · Cited by 375
Devaraj, S., & Jialal, I. (2000) · Circulation · doi:10.1161/01.cir.102.2.191 · Cited by 163
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Jialal, I., & Devaraj, S. (2000) · New England Journal of Medicine · doi:10.1056/nejm200006223422514 · Cited by 49
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Relations of plasma high-sensitivity C-reactive protein to traditional cardiovascular risk factors
Saito, M., Ishimitsu, T., Minami, J., Ono, H., Ohrui, M., & Matsuoka, H. (2003) · Atherosclerosis · doi:10.1016/s0021-9150(02)00380-5 · Cited by 239
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Jiang, R., Jacobs, D. R., Mayer‐Davis, E. J., Szklo, M., Herrington, D. M., Jenny, N. S., Kronmal, R. A., & Barr, R. G. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwj033 · Cited by 233
Inflammation, obesity and comorbidities: the role of diet
Bulló, M., Casas‐Agustench, P., Amigó‐Correig, P., Bartrina, J. A., & Salas‐Salvadó, J. (2007) · Public Health Nutrition · doi:10.1017/s1368980007000663 · Cited by 233
Tan, P., Sagoo, P., Chan, C. C. W., Yates, J., Campbell, J., Beutelspacher, S. C., Foxwell, B. M. J., Lombardi, G., & George, A. J. T. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.12.7633 · Cited by 224
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Devaraj, S., Tang, R., ADAMS-HUET, B. A., Harris, A., Seenivasan, T., de Lemos, J. A., & Jialal, I. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1392 · Cited by 150
Self-citationThe role of inflammation in the anaemia of end-stage renal disease
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Self-citationVitamin E and Risk of Type 2 Diabetes in the Women’s Health Study Randomized Controlled Trial
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Grundy, S. M. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02631-0 · Cited by 128
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Yu, Z., Malik, V., Keum, N., Hu, F. B., Giovannucci, E. L., Stampfer, M. J., Willett, W. C., Fuchs, C. S., & Bao, Y. (2016) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.134205 · Cited by 129
Sen, S., Rifas‐Shiman, S. L., Shivappa, N., Wirth, M. D., Hébert, J. R., Gold, D. R., Gillman, M. W., & Oken, E. (2016) · Journal of Nutrition · doi:10.3945/jn.115.225581 · Cited by 133
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Singh, U. S., & Jialal, I. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1331.019 · Cited by 119
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Wong, C. K., Ho, A. M. ‐., Tong, P. C. Y., Yeung, C. Y., Kong, A. P. S., Lun, S. W., Chan, J. C. N., & Lam, C. W. K. (2007) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2007.03389.x · Cited by 115
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Stenvinkel, P., Chung, S. H., Heimbürger, O., & Lindholm, B. (2001) · Peritoneal Dialysis International · doi:10.1177/089686080102103s27 · Cited by 114
Pierce, B. L., Neuhouser, M. L., Wener, M. H., Bernstein, L., Baumgartner, R., Ballard-Barbash, R. R., Gilliland, F. D., Baumgartner, K. B., Sorensen, B. E., McTiernan, A., et al. (2008) · Breast Cancer Research and Treatment · doi:10.1007/s10549-008-9985-5 · Cited by 112
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Wu, J. H. Y., Ward, N. C., Indrawan, A. P., Almeida, C.-A. M., Hodgson, J. M., Proudfoot, J. M., Puddey, I. B., & Croft, K. D. (2007) · Clinical Chemistry · doi:10.1373/clinchem.2006.076992 · Cited by 112
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Torres, J. L., & Ridker, P. M. (2003) · Current Opinion in Cardiology · doi:10.1097/00001573-200311000-00008 · Cited by 101
Fredrikson, G. N., Hedblad, B., Nilsson, J., Alm, R., Berglund, G. L., & Nilsson, J. (2004) · Metabolism · doi:10.1016/j.metabol.2004.06.010 · Cited by 100
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Stenvinkel, P. (2002) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/17.suppl_5.32 · Cited by 97
Vahid, F., Shivappa, N., Hekmatdoost, A., Hébert, J. R., Davoodi, S. H., & Sadeghi, M. R. (2017) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0274 · Cited by 97
Wang, X. L., Rainwater, D. L., Mahaney, M. C., & Stocker, R. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.3.649 · Cited by 94
Patrick, L., & Uzick, M. (2001) · PubMed · Cited by 90
Brüünsgaard, H. (2006) · PubMed · Cited by 90
Noh, H., Yu, M. R., Kim, H. J., Lee, J. H., Park, B., Wu, I., Matsumoto, M., & King, G. L. (2017) · Kidney International · doi:10.1016/j.kint.2017.02.013 · Cited by 90
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Ullegaddi, R., Powers, H. J., & Gariballa, S. (2006) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607106030002108 · Cited by 86
Vega‐López, S., Kaul, N., Devaraj, S., Cai, R. Y., German, B., & Jialal, I. (2004) · Metabolism · doi:10.1016/j.metabol.2003.09.012 · Cited by 82
Self-citationStroke: roles of B vitamins, homocysteine and antioxidants
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Block, G., Jensen, C. D., Dietrich, M., Norkus, E. P., Hudes, M. L., & Packer, L. (2004) · Journal of the American College of Nutrition · doi:10.1080/07315724.2004.10719354 · Cited by 82
Plasma C-reactive protein levels in severe diabetic ketoacidosis.
Dalton, R. R., Hoffman, W. H., Passmore, G. G., & Martin, S. L. A. (2003) · PubMed · Cited by 81
Smržová, J., Balla, J., & Barany, P. F. (2005) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfh1109 · Cited by 81
Stenvinkel, P. (2003) · Journal of Renal Nutrition · doi:10.1053/jren.2003.50018 · Cited by 78
Murer, S. B., Herter‐Aeberli, I., Braegger, C., Gittermann, M., Hersberger, M., Leonard, S. W., Taylor, A. W., Traber, M. G., & Zimmermann, M. B. (2013) · Journal of Nutrition · doi:10.3945/jn.113.185561 · Cited by 78
Causes and therapy of microinflammation in renal failure
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Vahid, F., Shivappa, N., Karamati, M., Naeini, A. J., Hébert, J. R., & Davoodi, S. H. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0395 · Cited by 78
Schober, F., Neumeier, M., Weigert, J., Wurm, S., Wanninger, J., Schäffler, A., Dada, A. M., Liebisch, G., Schmitz, G., Aslanidis, C., et al. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.07.106 · Cited by 76
Oliveira, A., Rodríguez‐Artalejo, F., & Lopes, C. M. M. (2009) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2009.61 · Cited by 74
Singh, U. S., Tabibian, J. H., Venugopal, S. K., Devaraj, S., & Jialal, I. (2005) · Clinical Chemistry · doi:10.1373/clinchem.2005.056093 · Cited by 72
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Bruunsgaard, H., Pedersen, B. K., Poulsen, H. E., Nyyssönen, K., Kaikkonen, J., & Salonen, J. T. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.4.1170 · Cited by 70
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Devaraj, S., O’Keefe, G. E., & Jialal, I. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0069 · Cited by 69
Self-citationUllegaddi, R., Powers, H. J., & Gariballa, S. (2005) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602248 · Cited by 69
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Fernández‐García, J. C., Cardona, F., & Tinahones, F. J. (2014) · Current Vascular Pharmacology · doi:10.2174/15701611113116660175 · Cited by 63
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The Antioxidant Vitamins C and E
Packer, L. (2003) · AOCS Publishing eBooks · doi:10.4324/9780429270710 · Cited by 59
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Al-Waili, N., Salom, K., Al-Ghamdi, A., Ansari, M. J., Al-Waili, A. N., & Al-Waili, T. N. (2013) · Journal of Medicinal Food · doi:10.1089/jmf.2012.0285 · Cited by 54
Role of C-reactive protein in the assessment of cardiovascular risk
Jialal, I., & Devaraj, S. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)03110-7 · Cited by 53
Self-citationSmith, K. S., Lee, C., Ridlington, J. W., Leonard, S. W., Devaraj, S., & Traber, M. G. (2003) · Lipids · doi:10.1007/s11745-003-1130-9 · Cited by 51
Self-citationDevaraj, S., Cabo-Chan, A. V., & Jialal, I. (2002) · Diabetes Care · doi:10.2337/diacare.25.3.524 · Cited by 50
Self-citationAge-related loss of associations between acute exercise-induced IL-6 and oxidative stress
Sacheck, J. M., Cannon, J. G., Hamada, K., Vannier, E. G., Blumberg, J. B., & Roubenoff, R. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00052.2005 · Cited by 49
Metadata
- Authors
- Devaraj, S., & Jialal, I.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Jialal, Ishwarlal
- Venue
- Free Radical Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 2000-10
- Volume
- 29
- Issue
- 8
- Pages
- 790-792
- ISSN
- 0891-5849 (ISSN-L)
- OpenAlex
- W2085598380
- Cited by
- 227
- References
- 9
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 5 · 2020: 4 · 2019: 3 · 2018: 7 · 2017: 8 · 2016: 8 · 2015: 9 · 2014: 4 · 2013: 8 · 2012: 5
- FWCI
- 10.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Free Radical Biology and Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- National Center for Complementary and Integrative Health (K-24AT00596, 1 RO1 AT00005-01, R01AT000005, K24AT000596)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Keywords
- alpha-tocopherol, vitamin E supplementation, type 2 diabetes, C-reactive protein, interleukin-6, monocytes, inflammation, macrovascular complications, atherosclerosis, antioxidant therapy
- MeSH terms
- Antioxidants, Arteriosclerosis, C-Reactive Protein, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Humans, Monocytes, Vitamin E, Interleukin-6, Case-Control Studies
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