The validity of the diagnosis of acute myocardial infarction in routine statistics: a comparison of mortality and hospital discharge data with the Danish MONICA registry
Abstract
We analyzed the validity of the diagnosis of acute myocardial infarction (MI) in national registries by individual record linkage with the Danish MONICA registry. MI events were identified by record linkage between The National Hospital Registry and The National Death Registry. The sensitivity and specificity were estimated based on three different definitions of an MI event. For events with MI as the primary diagnosis or underlying cause of death the predictive value was 93.6% and sensitivity 77.6% when compared to DANMONICA definite or possible MI. Compared to DANMONICA, definite MI the predictive value was 75.0% and the sensitivity 92.8%. When secondary diagnosis and contributory cause of death were included, the sensitivity increased and the predictive value decreased only slightly. The combination of the national registries was found to be a valid and powerful tool for monitoring the population incidence of MI.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Myocardial infarction and cancer as a primary diagnosis or underlying cause of death has been shown to have high diagnostic validity.
“Further, myocardial infarction and cancer as a primary diagnosis or underlying cause of death has been shown to have high diagnostic validity.77,78”
Cited by
Sorted by citations
External review and validation of the Swedish national inpatient register
Ludvigsson, J. F., Andersson, E., Ekbom, A., Feychting, M., Kim, J.-L., Reuterwall, C., Heurgren, M., & Olausson, P. O. (2011) · BMC Public Health · doi:10.1186/1471-2458-11-450 · Cited by 5,055 · see citing works
Childhood Body-Mass Index and the Risk of Coronary Heart Disease in Adulthood
Baker, J. L., Olsen, L. W., & Sørensen, T. I. A. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa072515 · Cited by 1,679 · see citing works
Willum Hansen, T., Staessen, J. A., Torp-Pedersen, C., Rasmussen, S., Thijs, L., Ibsen, H., & Jeppesen, J. (2006) · Circulation · doi:10.1161/circulationaha.105.579342 · Cited by 1,515 · see citing works
Olesen, J. B., Lip, G. Y. H., Hansen, M. L., Hansen, P. R., Tolstrup, J. S., Lindhardsen, J., Selmer, C., Ahlehoff, O., Olsen, A.-M. S., Gislason, G. H., et al. (2011) · BMJ · doi:10.1136/bmj.d124 · Cited by 1,428 · see citing works
Stroke and bleeding in atrial fibrillation with chronic kidney disease
Olesen, J. B., Lip, G. Y. H., Kamper, A.-L., Hommel, K., Køber, L., Lane, D. A., Lindhardsen, J., Gislason, G. H., & Torp-Pedersen, C. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1105594 · Cited by 930 · see citing works
Thrombotic stroke and myocardial infarction with hormonal contraception
Lidegaard, Ø., Løkkegaard, E., Jensen, A., Skovlund, C. W., & Keiding, N. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1111840 · Cited by 607 · see citing works
Lip, G., Lindhardsen, J., Lane, D., Ahlehoff, O., Hansen, M., Raunsø, J., Tolstrup, J., Hansen, P., Gislason, G., Torp-Pedersen, C., et al. (2011) · Thrombosis and Haemostasis · doi:10.1160/th11-05-0364 · Cited by 428 · see citing works
Schramm, T. K., Gislason, G. H., Vaag, A., Rasmussen, J. N., Folke, F., Hansen, M. L., Fosbøl, E. L., Køber, L., Norgaard, M. L., Madsen, M., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr077 · Cited by 418 · see citing works
Self-citationSelmer, C., Olesen, J. B., Hansen, M. L., Lindhardsen, J., Olsen, A.-M. S., Madsen, J. C., Faber, J., Hansen, P. R., Pedersen, O. D., Torp-Pedersen, C., et al. (2012) · BMJ · doi:10.1136/bmj.e7895 · Cited by 323 · see citing works
Risk prediction is improved by adding markers of subclinical organ damage to SCORE
Sehestedt, T., Jeppesen, J., Hansen, T. W., Wachtell, K., Ibsen, H., Torp-Petersen, C., Hildebrandt, P., & Olsen, M. H. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehp546 · Cited by 315 · see citing works
Selmer, C., Olesen, J. B., Hansen, M. L., von Kappelgaard, L. M., Madsen, J. C., Hansen, P. R., Pedersen, O. D., Faber, J., Torp-Pedersen, C., & Gislason, G. H. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4184 · Cited by 288 · see citing works
Laursen, T. M., Munk-Olsen, T., Agerbo, E., Gasse, C., & Mortensen, P. B. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.61 · Cited by 271 · see citing works
Staerk, L., Lip, G. Y. H., Olesen, J. B., Fosbøl, E. L., Pallisgaard, J. L., Bonde, A. N., Gundlund, A., Lindhardt, T. B., Hansen, M. L., Torp-Pedersen, C., et al. (2015) · BMJ · doi:10.1136/bmj.h5876 · Cited by 146 · see citing works
Karasoy, D., Gislason, G. H., Hansen, J., Johannessen, A., Køber, L., Hvidtfeldt, M., Özcan, C., Torp-Pedersen, C., & Hansen, M. L. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehu421 · Cited by 132 · see citing works
Subherwal, S., Patel, M. R., Kober, L., Peterson, E. D., Bhatt, D. L., Gislason, G. H., Olsen, A.-M. S., Jones, W. S., Torp-Pedersen, C., & Fosbol, E. L. (2015) · European Journal of Preventive Cardiology · doi:10.1177/2047487313519344 · Cited by 129 · see citing works
Familial aggregation of lone atrial fibrillation in young persons
Øyen, N., Ranthe, M. F., Carstensen, L., Boyd, H. A., Olesen, M. S., Olesen, S.-P., Wohlfahrt, J., & Melbye, M. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.03.046 · Cited by 126 · see citing works
Nielsen, J. B., Pietersen, A., Graff, C., Lind, B., Struijk, J. J., Olesen, M. S., Haunsø, S., Gerds, T. A., Ellinor, P. T., Køber, L., et al. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2013.04.012 · Cited by 126 · see citing works
Pregnancy Loss and Later Risk of Atherosclerotic Disease
Ranthe, M. F., Andersen, E. A. W., Wohlfahrt, J., Bundgaard, H., Melbye, M., & Boyd, H. A. (2013) · Circulation · doi:10.1161/circulationaha.112.000285 · Cited by 117 · see citing works
Rasmussen, K. L., Tybjærg-Hansen, A., Nordestgaard, B. G., & Frikke-Schmidt, R. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz402 · Cited by 86 · see citing works
Gedeborg, R., Furebring, M., & Michaëlsson, K. (2007) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2006.05.013 · Cited by 80 · see citing works
Svensson, E., Baggesen, L. M., Johnsen, S. P., Pedersen, L., Nørrelund, H., Buhl, E. S., Haase, C. L., & Thomsen, R. W. (2017) · Diabetes Care · doi:10.2337/dc16-2271 · Cited by 77 · see citing works
Adiponectin, type 2 diabetes and cardiovascular risk
Lindberg, S., Jensen, J. S., Bjerre, M., Pedersen, S. H., Frystyk, J., Flyvbjerg, A., Galatius, S., Jeppesen, J., & Mogelvang, R. (2015) · European Journal of Preventive Cardiology · doi:10.1177/2047487313514894 · Cited by 66 · see citing works
Ruwald, M. H., Hansen, M. L., Lamberts, M., Hansen, C. M., Numé, A.-K., Vinther, M., Køber, L., Torp-Pedersen, C., Hansen, J., & Gislason, G. H. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.07.041 · Cited by 59 · see citing works
Smolderen, K. G., Ameli, O., Chaisson, C. E., Heath, K., & Mena-Hurtado, C. (2022) · AJPM Focus · doi:10.1016/j.focus.2022.100016 · Cited by 11 · see citing works
Smolderen, K. G., Heath, K., Scherr, T., Bauzon, S. R., Howell, A. N., & Mena-Hurtado, C. (2022) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2022.01.134 · Cited by 9 · see citing works
- Authors
- Madsen, M.
- Affiliations
- Danish National Institute of Public Health (DK)
- Corresponding author
- Madsen, M
- Venue
- Journal of Clinical Epidemiology
- Publisher
- Elsevier BV
- Published
- 2003-02
- Volume
- 56
- Issue
- 2
- Pages
- 124-130
- ISSN
- 0895-4356 (ISSN-L)
- OpenAlex
- W2087815860
- Cited by
- 460
- References
- 0
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 3 · 2023: 10 · 2022: 13 · 2021: 9 · 2020: 9 · 2019: 11 · 2018: 14 · 2017: 15 · 2016: 34 · 2015: 34 · 2014: 36 · 2013: 46 · 2012: 58
- FWCI
- 30.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Topics
- Health Sciences › Health Professions › Health Information Management › Medical Coding and Health Information
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Keywords
- acute myocardial infarction, diagnostic validity, data linkage, sensitivity and specificity, causes of death, Denmark
- MeSH terms
- Adult, Aged, Cause of Death, Denmark, Female, Humans, Male, Medical Record Linkage, Middle Aged, Mortality, Myocardial Infarction, Patient Discharge, Predictive Value of Tests, Registries, Sensitivity and Specificity, Reproducibility of Results, Multicenter Studies as Topic, Incidence, Survival Analysis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review