Piccolo, a presynaptic zinc finger protein structurally related to bassoon

The synaptic vesicle cycle: a cascade of protein–protein interactions

Südhof, T. (1995) · Nature · doi:10.1038/375645a0 · Cited by 2,002 · see citing works

Coiled coils: new structures and new functions.

Lupas, A. (1996) · TIBS -Trends in Biochemical Sciences. Regular ed · doi:10.1016/s0968-0004(96)10052-9 · Cited by 1,191 · see citing works

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

Kozak, M. (1987) · Journal of Molecular Biology · doi:10.1016/0022-2836(87)90418-9 · Cited by 1,182 · see citing works

Prediction of the Coding Sequences of Unidentified Human Genes. IX. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro

Nagase, T. (1998) · DNA Research · doi:10.1093/dnares/5.1.31 · Cited by 845 · see citing works

Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

Balch, W. E., Dunphy, W. G., Braell, W. A., & Rothman, J. E. (1984) · Cell · doi:10.1016/0092-8674(84)90019-9 · Cited by 696 · see citing works

Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion

Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K., & Südhof, T. C. (1997) · Nature · doi:10.1038/41580 · Cited by 684 · see citing works

Natural history of Williams syndrome: Physical characteristics

Morris, C. A., Demsey, S. A., Leonard, C. O., Dilts, C., & Blackburn, B. L. (1988) · The Journal of Pediatrics · doi:10.1016/s0022-3476(88)80272-5 · Cited by 670 · see citing works

Distinct pools of synaptic vesicles in neurotransmitter release

Pieribone, V. A., Shupliakov, O., Brodin, L., Hilfiker, S., Czernik, A. J., & Greengard, P. (1995) · Nature · doi:10.1038/375493a0 · Cited by 532 · see citing works

The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1.

Hirokawa, N., Sobue, K., Kanda, K., Harada, A., & Yorifuji, H. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.1.111 · Cited by 501 · see citing works

PDZ Proteins Organize Synaptic Signaling Pathways

Craven, S. E., & Bredt, D. S. (1998) · Cell · doi:10.1016/s0092-8674(00)81179-4 · Cited by 491 · see citing works

Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals

Dieck, S., Sanmartí-Vila, L., Langnaese, K., Richter, K., Kindler, S., Soyke, A., Wex, H., Smalla, K.-H., Kämpf, U., Fränzer, J.-T., et al. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.2.499 · Cited by 482 · see citing works

Synaptotagmins: C2-domain proteins that regulate membrane traffic.

Südhof, T., & Rizo, J. (1996) · Neuron · doi:10.1016/s0896-6273(00)80171-3 · Cited by 450 · see citing works

SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo.

Müller, B., Kistner, U., Kindler, S., Chung, W. J., Kuhlendahl, S., Fenster, S. D., Lau, L.-F., Veh, R., Huganir, R., Gundelfinger, E., et al. (1996) · Neuron · doi:10.1016/s0896-6273(00)80157-9 · Cited by 435 · see citing works

The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion

Geppert, M., Goda, Y., Stevens, C., & Südhof, T. (1997) · Nature · doi:10.1038/42954 · Cited by 422 · see citing works

A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.

David, C., McPherson, P. S., Mundigl, O., & Camilli, P. V. D. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.1.331 · Cited by 409 · see citing works

Neurotransmitter release — four years of SNARE complexes

Hanson, P. I., Heuser, J. E., & Jahn, R. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80057-8 · Cited by 394 · see citing works

Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin

Shirataki, H., Kaibuchi, K., Sakoda, T., Kishida, S., Yamaguchi, T., Wada, K., Miyazaki, M., & Takai, Y. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.4.2061-2068.1993 · Cited by 393 · see citing works

The SH3p4/Sh3p8/SH3p13 protein family: Binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain

Ringstad, N., Nemoto, Y., & Camilli, P. V. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8569 · Cited by 390 · see citing works

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A.

Ostermeier, C., & Brunger, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80549-8 · Cited by 363 · see citing works

The LIM domain: a new structural motif found in zinc-finger-like proteins

Sánchez-Garcı́a, I., & Rabbitts, T. H. (1994) · Trends in Genetics · doi:10.1016/0168-9525(94)90034-5 · Cited by 349 · see citing works

The organization of cytoplasm at the presynaptic active zone of a central nervous system synapse

Landis, D. M. D., Hall, A. K., Weinstein, L. A., & Reese, T. S. (1988) · Neuron · doi:10.1016/0896-6273(88)90140-7 · Cited by 333 · see citing works

Syndapin I, a Synaptic Dynamin-binding Protein that Associates with the Neural Wiskott-Aldrich Syndrome Protein

Qualmann, B., Roos, J., DiGregorio, P. J., & Kelly, R. B. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.2.501 · Cited by 294 · see citing works

Intersectin, a Novel Adaptor Protein with Two Eps15 Homology and Five Src Homology 3 Domains

Yamabhai, M., Hoffman, N. G., Hardison, N. L., McPherson, P. S., Castagnoli, L., Cesareni, G., & Kay, B. K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.47.31401 · Cited by 285 · see citing works

Molecular Mechanisms in Synaptic Vesicle Endocytosis and Recycling

Camilli, P. V. D., & Takei, K. (1996) · Neuron · doi:10.1016/s0896-6273(00)80068-9 · Cited by 228 · see citing works

Dap160, a Neural-specific Eps15 Homology and Multiple SH3 Domain-containing Protein That Interacts with DrosophilaDynamin

Roos, J., & Kelly, R. B. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.30.19108 · Cited by 205 · see citing works

The Role of GTP-Binding Proteins in Transport Along the Exocytic Pathway

Ferro‐Novick, S., & Novick, P. (1993) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.09.110193.003043 · Cited by 201 · see citing works

Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C.

Cai, L., Takei, K., Geppert, M., Daniell, L., Stenius, K., Chapman, E., Jahn, R., Camilli, P. D., & Südhof, T. (1994) · Neuron · doi:10.1016/0896-6273(94)90254-2 · Cited by 194 · see citing works

The connections between bipolar cells and photoreceptors in the retina of the domestic cat

Boycott, B. B., & Kolb, H. (1973) · The Journal of Comparative Neurology · doi:10.1002/cne.901480106 · Cited by 179 · see citing works

Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition

Daniels, D. L., Cohen, A. R., Anderson, J. M., & Brünger, A. T. (1998) · Nature Structural Biology · doi:10.1038/nsb0498-317 · Cited by 178 · see citing works

Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix.

Cases-Langhoff, C., Voss, B., Garner, A. M., APPELTAUER, U., Takei, K., Kindler, S., Veh, R. W., Camilli, P. V. D., Gundelfinger, E. D., & Garner, C. C. (1996) · PubMed · Cited by 176 · see citing works

Differential expression of the presynaptic cytomatrix protein bassoon among ribbon synapses in the mammalian retina

Brandstätter, J. H., Fletcher, E. L., Garner, C. C., Gundelfinger, E. D., & Wässle, H. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00793.x · Cited by 165 · see citing works

Synaptic structure and function: Dynamic organization yields architectural precision

Burns, M. E., & Augustine, G. J. (1995) · Cell · doi:10.1016/0092-8674(95)90160-4 · Cited by 164 · see citing works

Distinct Ca-dependent Properties of the First and Second C-domains of Synaptotagmin I (*)

Sugita, S., Hata, Y., & Südhof, T. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.3.1262 · Cited by 128 · see citing works

Mechanism of Action of rab3A in Mossy Fiber LTP

Lónárt, G., Janz, R., Johnson, K. M., & Südhof, T. C. (1998) · Neuron · doi:10.1016/s0896-6273(00)80631-5 · Cited by 122 · see citing works

Isolation and Characterization of a Dual Prenylated Rab and VAMP2 Receptor

Martincic, I., Peralta, M. D., & Ngsee, J. K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.43.26991 · Cited by 119 · see citing works

Complete physical map of the common deletion region in Williams syndrome and identification and characterization of three novel genes

Meng, X., Lu, X., Li, Z., Green, E. D., Massa, H. F., Trask, B. J., Morris, C. A., & Keating, M. T. (1998) · Human Genetics · doi:10.1007/s004390050874 · Cited by 111 · see citing works

A Functional Role for GTP-Binding Proteins in Synaptic Vesicle Cycling

Hess, S., Doroshenko, P. A., & Augustine, G. J. (1993) · Science · doi:10.1126/science.8438167 · Cited by 109 · see citing works

Astrocytes protect neurons from neurotoxic injury by serum glutamate

Ye, Z., & Sontheimer, H. W. (1998) · Glia · doi:10.1002/(sici)1098-1136(199803)22:3 · Cited by 94 · see citing works

Cytoplasmic architecture of the axon terminal: Filamentous strands specifically associated with synaptic vesicles

Gotow, T., Miyaguchi, K., & Hashimoto, P. H. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90143-c · Cited by 91 · see citing works

Noc2, a Putative Zinc Finger Protein Involved in Exocytosis in Endocrine Cells

Kotake, K., Ozaki, N., Mizuta, M., Sekiya, S., Inagaki, N., & Seino, S. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.47.29407 · Cited by 78 · see citing works

Synaptic proteins and the assembly of synaptic junctions

Garner, C. C., & Kindler, S. (1996) · Trends in Cell Biology · doi:10.1016/s0962-8924(96)10036-2 · Cited by 69 · see citing works

Protein components of a rat brain synaptic junctional protein preparation

Langnaese, K., Seidenbecher, C. I., Wex, H., Seidel, B., Hartung, K., APPELTAUER, U., Garner, A. M., Voss, B., Mueller, B., Garner, C. C., et al. (1996) · Molecular Brain Research · doi:10.1016/s0169-328x(96)00147-7 · Cited by 66 · see citing works

Interaction Cloning and Characterization of the cDNA Encoding the Human Prenylated Rab Acceptor (PRA1)

Bucci, C., Chiariello, M., Lattero, D., Maiorano, M., & Bruni, C. B. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0651 · Cited by 62 · see citing works

Functional analysis of the guanylate kinase‐like domain in the synapse‐associated protein SAP97

Kuhlendahl, S., Spangenberg, O., Konrad, M., Kim, E., & Garner, C. C. (1998) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1998.2520305.x · Cited by 53 · see citing works

Rab1a and Multiple Other Rab Proteins Are Associated with the Transcytotic Pathway in Rat Liver

Jin, M., Saucan, L., Farquhar, M. G., & Palade, G. E. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.47.30105 · Cited by 48 · see citing works

Cloning and mapping of ZNF231, a novel brain-specific gene encoding neuronal double zinc finger protein whose expression is enhanced in a neurodegenerative disorder, multiple system atrophy (MSA).

Hashida, H., Goto, J., Zhao, N., Takahashi, N., Hirai, M., Kanazawa, I., & Sakaki, Y. (1998) · Genomics · doi:10.1006/geno.1998.5516 · Cited by 40 · see citing works

The Presynaptic Cytomatrix Protein Bassoon: Sequence and Chromosomal Localization of the HumanBSNGene

Winter, C., Dieck, S. T., Boeckers, T. M., Bockmann, J., Kämpf, U., Sanmartı́-Vila, L., Langnaese, K., Altrock, W. D., Stümm, M., Soyke, A., et al. (1999) · Genomics · doi:10.1006/geno.1999.5788 · Cited by 28 · see citing works

Autoradiographic and in situ hybridization localization of corticotropin-releasing factor 1 and 2 receptors in nonhuman primate brain

S�nchez, M. M., Young, L. J., Plotsky, P. M., & Insel, T. R. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990607)408:3

Short-Term Synaptic Plasticity

Zucker, R. S., & Regehr, W. G. (2002) · Annual Review of Physiology · doi:10.1146/annurev.physiol.64.092501.114547 · Cited by 5,068 · see citing works

The Presynaptic Active Zone

Südhof, T. C. (2012) · Neuron · doi:10.1016/j.neuron.2012.06.012 · Cited by 1,062 · see citing works

Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila

Wagh, D. A., Rasse, T. M., Asan, E., Hofbauer, A., Schwenkert, I., Dürrbeck, H., Buchner, S., Dabauvalle, M.-C., Schmidt, M., Qin, G., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.02.008 · Cited by 908 · see citing works

Superresolution Imaging of Chemical Synapses in the Brain

Dani, A., Huang, B., Bergan, J. F., Dulac, C. G., & Zhuang, X. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.021 · Cited by 718 · see citing works

Synaptic Vesicle ExocytosisPreprint

Südhof, T. C., & Rizo, J. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005637 · Cited by 502 · see citing works

Assembly of New Individual Excitatory Synapses

Friedman, H., Bresler, T., Garner, C. C., & Ziv, N. E. (2000) · Neuron · doi:10.1016/s0896-6273(00)00009-x · Cited by 489 · see citing works

Targeting Rab GTPases to distinct membrane compartments

Pfeffer, S. R., & Aivazian, D. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1500 · Cited by 462 · see citing works

The Presynaptic Active Zone Protein Bassoon Is Essential for Photoreceptor Ribbon Synapse Formation in the Retina

Dick, O., Dieck, S. T., Altrock, W. D., Ammermüller, J., Weiler, R., Garner, C. C., Gundelfinger, E. D., & Brandstätter, J. H. (2003) · Neuron · doi:10.1016/s0896-6273(03)00086-2 · Cited by 459 · see citing works

Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming

Betz, A., Thakur, P., Junge, H. J., Ashery, U., Rhee, J.-S., Scheuss, V., Rosenmund, C., Rettig, J., & Brose, N. (2001) · Neuron · doi:10.1016/s0896-6273(01)00272-0 · Cited by 425 · see citing works

Assembling the Presynaptic Active Zone

Zhai, R. G., Vardinon-Friedman, H., Cases-Langhoff, C., Becker, B., Gundelfinger, E. D., Ziv, N. E., & Garner, C. C. (2001) · Neuron · doi:10.1016/s0896-6273(01)00185-4 · Cited by 424 · see citing works

Chlorotoxin Inhibits Glioma Cell Invasion via Matrix Metalloproteinase-2

Deshane, J. S., Garner, C. C., & Sontheimer, H. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m205662200 · Cited by 412 · see citing works

Molecular dissection of the photoreceptor ribbon synapse

Dieck, S. T., Altrock, W. D., Kessels, M. M., Qualmann, B., Regus‐Leidig, H., Brauner, D., Fejtová, A., Bracko, O., Gundelfinger, E. D., & Brandstätter, J. H. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200408157 · Cited by 401 · see citing works

Highwire Regulates Synaptic Growth in Drosophila

Wan, H. I., DiAntonio, A., Fetter, R. D., Bergstrom, K., Strauß, R., & Goodman, C. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)81166-6 · Cited by 398 · see citing works

Unitary Assembly of Presynaptic Active Zones from Piccolo-Bassoon Transport Vesicles

Shapira, M., Zhai, R. G., Dresbach, T., Bresler, T., Torres, V. I., Gundelfinger, E. D., Ziv, N. E., & Garner, C. C. (2003) · Neuron · doi:10.1016/s0896-6273(03)00207-1 · Cited by 354 · see citing works

Diversification of synaptic strength: presynaptic elements

Atwood, H. L., & Karunanithi, S. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn876 · Cited by 346 · see citing works

O-Linked N-Acetylglucosamine Proteomics of Postsynaptic Density Preparations Using Lectin Weak Affinity Chromatography and Mass Spectrometry

Vosseller, K., Trinidad, J. C., Chalkley, R. J., Specht, C. G., Thalhammer, A., Lynn, A. J., Snedecor, J., Guan, S., Medzihradszky, K. F., Maltby, D. A., et al. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.t500040-mcp200 · Cited by 346 · see citing works

Molecular organization of the presynaptic active zone

Schoch, S., & Gundelfinger, E. D. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0244-y · Cited by 334 · see citing works

C ELL B IOLOGY OF THE P RESYNAPTIC T ERMINAL

Murthy, V. N., & Camilli, P. V. D. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131445 · Cited by 330 · see citing works

Three-Dimensional Architecture of Presynaptic Terminal Cytomatrix

Siksou, L., Rostaing, P., Lechaire, J., Boudier, T., Ohtsuka, T., Fejtová, A., Kao, H., Greengard, P., Gundelfinger, E. D., Triller, A., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1773-07.2007 · Cited by 329 · see citing works

Phosphoinositides in membrane traffic at the synapse

Cremona, O., & Camilli, P. V. D. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.6.1041 · Cited by 324 · see citing works

Cast

Ohtsuka, T., Takao‐Rikitsu, E., Inoue, E., Inoue, M., Takeuchi, M., Matsubara, K., Deguchi‐Tawarada, M., Satoh, K., Morimoto, K., Nakanishi, H., et al. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202083 · Cited by 295 · see citing works

The Architecture of the Active Zone in the Presynaptic Nerve Terminal

Zhai, R. G., & Bellen, H. J. (2004) · Physiology · doi:10.1152/physiol.00014.2004 · Cited by 291 · see citing works

Actin-Dependent Regulation of Neurotransmitter Release at Central Synapses

Morales, M., Colicos, M. A., & Goda, Y. (2000) · Neuron · doi:10.1016/s0896-6273(00)00064-7 · Cited by 300 · see citing works

Temporal and spatial coordination of exocytosis and endocytosis

Gundelfinger, E. D., Kessels, M. M., & Qualmann, B. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1016 · Cited by 263 · see citing works

Stages of Synapse Development Defined by Dependence on F-Actin

Zhang, W., & Benson, D. L. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05169.2001 · Cited by 262 · see citing works

Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon

Altrock, W. D., tom Dieck, S., Sokolov, M., Meyer, A. C., Sigler, A., Brakebusch, C., Fässler, R., Richter, K., Boeckers, T. M., Potschka, H., et al. (2003) · Neuron · doi:10.1016/s0896-6273(03)00088-6 · Cited by 258 · see citing works

Regulation of Presynaptic Terminal Organization by C. elegans RPM-1, a Putative Guanine Nucleotide Exchanger with a RING-H2 Finger Domain

Zhen, M., Huang, X., Bamber, B. A., & Jin, Y. (2000) · Neuron · doi:10.1016/s0896-6273(00)81167-8 · Cited by 233 · see citing works

Onset Coding Is Degraded in Auditory Nerve Fibers from Mutant Mice Lacking Synaptic Ribbons

Buran, B. N., Strenzke, N., Neef, A., Gundelfinger, E. D., Moser, T., & Liberman, M. C. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0389-10.2010 · Cited by 226 · see citing works

Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release

Takao-Rikitsu, E., Mochida, S., Inoue, E., Deguchi-Tawarada, M., Inoue, M., Ohtsuka, T., & Takai, Y. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200307101 · Cited by 221 · see citing works

Molecular determinants of presynaptic active zones

Garner, C. C., Kindler, S., & Gundelfinger, E. D. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00093-3 · Cited by 221 · see citing works

The presynaptic cytomatrix of brain synapses

Dresbach, T., Qualmann, B., Kessels, M. M., Garner, C. C., & Gundelfinger, E. D. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000781 · Cited by 216 · see citing works

Direct Interaction of the Rab3 Effector RIM with Ca2+Channels, SNAP-25, and Synaptotagmin

Coppola, T., Magnin, S., Perret-Menoud, V., Gattesco, S., Schiavo, G., & Regazzi, R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100929200 · Cited by 211 · see citing works

Association of the Kinesin Motor KIF1A with the Multimodular Protein Liprin-α

Shin, H., Wyszynski, M. W., Huh, K. H., Valtschanoff, J. G., Lee, J.-R., Ko, J., Streuli, M., Weinberg, R. J., Sheng, M., & Kim, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211874200 · Cited by 207 · see citing works

Sensory Processing at Ribbon Synapses in the Retina and the Cochlea

Moser, T., Grabner, C. P., & Schmitz, F. (2019) · Physiological Reviews · doi:10.1152/physrev.00026.2018 · Cited by 206 · see citing works

Molecular mechanisms of CNS synaptogenesis

Garner, C. C., Zhai, R. G., Gundelfinger, E. D., & Ziv, N. E. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02152-5 · Cited by 206 · see citing works

A role for ion channels in glioma cell invasion

McFerrin, M. B., & Sontheimer, H. W. (2005) · Neuron Glia Biology · doi:10.1017/s1740925x06000044 · Cited by 205 · see citing works

Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone

Gundelfinger, E. D., Reissner, C., & Garner, C. C. (2016) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2015.00019 · Cited by 203 · see citing works

Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis

Mukherjee, K., Yang, X., Gerber, S. H., Kwon, H.-B., Ho, A., Castillo, P. E., Liu, X., & Südhof, T. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002307107 · Cited by 195 · see citing works

The molecular machinery of neurotransmitter release (Nobel lecture).

Südhof, T. (2014) · Angewandte Chemie · doi:10.1002/anie.201406359 · Cited by 173 · see citing works

Interaction of the ERC Family of RIM-binding Proteins with the Liprin-α Family of Multidomain Proteins

Ko, J., Na, M., Kim, S.-H., Lee, J.-R., & Kim, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307561200 · Cited by 185 · see citing works

The SAD-1 Kinase Regulates Presynaptic Vesicle Clustering and Axon Termination

Crump, J. G., Zhen, M., Jin, Y., & Bargmann, C. I. (2001) · Neuron · doi:10.1016/s0896-6273(01)00184-2 · Cited by 181 · see citing works

Interaction of ATP Sensor, cAMP Sensor, Ca2+ Sensor, and Voltage-dependent Ca2+ Channel in Insulin Granule Exocytosis

Shibasaki, T., Sunaga, Y., Fujimoto, K., Kashima, Y., & Seino, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309068200 · Cited by 175 · see citing works

Interaction between Liprin-α and GIT1 Is Required for AMPA Receptor Targeting

Ko, J., Kim, S.-H., Valtschanoff, J. G., Shin, H., Lee, J.-R., Sheng, M., Premont, R. T., Weinberg, R. J., & Kim, E. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01667.2003 · Cited by 160 · see citing works

Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis

Leal‐Ortiz, S., Waites, C. L., Terry-Lorenzo, R. T., Zamorano, P. L., Gundelfinger, E. D., & Garner, C. C. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200711167 · Cited by 157 · see citing works

Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation

Waites, C. L., Leal‐Ortiz, S., Okerlund, N. D., Dalke, H., Fejtová, A., Altrock, W. D., Gundelfinger, E. D., & Garner, C. C. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.27 · Cited by 154 · see citing works

How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs

Acuna, C., Liu, X., & Südhof, T. C. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.042 · Cited by 154 · see citing works

Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: Comparison with Bassoon

Dick, O., Hack, I., Altrock, W. D., Garner, C. C., Gundelfinger, E. D., & Brandstätter, J. H. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1344 · Cited by 153 · see citing works

Distinct Initial SNARE Configurations Underlying the Diversity of Exocytosis

Kasai, H., Takahashi, N., & Tokumaru, H. (2012) · Physiological Reviews · doi:10.1152/physrev.00007.2012 · Cited by 150 · see citing works

The actin cytoskeleton and neurotransmitter release: An overview

Doussau, F. (2000) · Biochimie · doi:10.1016/s0300-9084(00)00217-0 · Cited by 149 · see citing works

Presynaptic Clustering of mGluR7a Requires the PICK1 PDZ Domain Binding Site

Boudin, H., Doan, A., Xia, J., Shigemoto, R., Huganir, R. L., Worley, P. F., & Craig, A. M. (2000) · Neuron · doi:10.1016/s0896-6273(00)00127-6 · Cited by 149 · see citing works

Molecular mechanisms of active zone function

Rosenmund, C., Rettig, J., & Brose, N. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.09.011 · Cited by 143 · see citing works

Molecular heterogeneity of central synapses: afferent and target regulation

Craig, A. M., & Boudin, H. (2001) · Nature Neuroscience · doi:10.1038/88388 · Cited by 140 · see citing works

Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty‐seeking behavior

Boyl, P. P., Nardo, A. D., Mulle, C., Sassoé‐Pognetto, M., Panzanelli, P., Mele, A., Kneussel, M., Costantini, V. J. A., Perlas, E., Massimi, M., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601737 · Cited by 139 · see citing works

The GIT Family of Proteins Forms Multimers and Associates with the Presynaptic Cytomatrix Protein Piccolo

Kim, S.-H., Ko, J., Shin, H., Lee, J.-R., Lim, C., Han, J., Altrock, W. D., Garner, C. C., Gundelfinger, E. D., Premont, R. T., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212287200 · Cited by 139 · see citing works

Docking of Secretory Vesicles Is Syntaxin Dependent

de Wit, H., Cornelisse, L. N., Toonen, R. F. G., & Verhage, M. (2006) · PLoS ONE · doi:10.1371/journal.pone.0000126 · Cited by 130 · see citing works

The molecular machinery of synaptic vesicle exocytosis

Li, L., & Chin, L. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2240-7 · Cited by 126 · see citing works

Evolutionarily Conserved Multiple C2 Domain Proteins with Two Transmembrane Regions (MCTPs) and Unusual Ca2+ Binding Properties*

Shin, O., Han, W., Wang, Y., & Südhof, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m407305200 · Cited by 116 · see citing works

Relating structure and function of inner hair cell ribbon synapses

Wichmann, C., & Moser, T. (2015) · Cell and Tissue Research · doi:10.1007/s00441-014-2102-7 · Cited by 123 · see citing works

Active Zones and the Readily Releasable Pool of Synaptic Vesicles at the Neuromuscular Junction of the Mouse

Ruiz, R., Cano, R., Casañas, J. J., Gaffield, M. A., Betz, W. J., & Tabares, L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4663-10.2011 · Cited by 121 · see citing works

Chronic dry eye induced corneal hypersensitivity, neuroinflammatory responses, and synaptic plasticity in the mouse trigeminal brainstem

Fakih, D., Zhao, Z., Nicolle, P., Reboussin, É., Joubert, F., Luzu, J., Labbé, A., Rostène, W. H., Baudouin, C., Parsadaniantz, S. M., et al. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1656-4 · Cited by 118 · see citing works

Structural and functional diversity generated by alternative mRNA splicing

Stetefeld, J., & Rüegg, M. A. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.07.001 · Cited by 117 · see citing works

Profilin1 biology and its mutation, actin(g) in disease

Alkam, D., Feldman, E. Z., Singh, A., & Kiaei, M. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2372-1 · Cited by 114 · see citing works

Voltage-Gated Calcium Channels: Key Players in Sensory Coding in the Retina and the Inner Ear

Pangršič, T., Singer, J. H., & Koschak, A. (2018) · Physiological Reviews · doi:10.1152/physrev.00030.2017 · Cited by 113 · see citing works

Functional regions of the presynaptic cytomatrix protein bassoon: significance for synaptic targeting and cytomatrix anchoring

Dresbach, T., Hempelmann, A., Spilker, C., Dieck, S. T., Altrock, W. D., Zuschratter, W., Garner, C. C., & Gundelfinger, E. D. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00015-0 · Cited by 113 · see citing works

SAD: A Presynaptic Kinase Associated with Synaptic Vesicles and the Active Zone Cytomatrix that Regulates Neurotransmitter Release

Inoue, E., Mochida, S., Takagi, H., Higa, S., Deguchi‐Tawarada, M., Takao‐Rikitsu, E., Inoue, M., Yao, I., Takeuchi, K., Kitajima, I., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.018 · Cited by 113 · see citing works

Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon

Fejtová, A., Davydova, D., Bischof, F., Lazarevic, V., Altrock, W. D., Romorini, S., Schöne, C., Zuschratter, W., Kreutz, M. R., Garner, C. C., et al. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200807155 · Cited by 113 · see citing works

Assembly of Active Zone Precursor Vesicles

Dresbach, T., Torres, V. I., Wittenmayer, N., Altrock, W. D., Zamorano, P. L., Zuschratter, W., Nawrotzki, R., Ziv, N. E., Garner, C. C., & Gundelfinger, E. D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508784200 · Cited by 106 · see citing works

Binding to Rab3A-interacting Molecule RIM Regulates the Presynaptic Recruitment of Munc13-1 and ubMunc13-2

Andrews-Zwilling, Y. S., Kawabe, H., Reim, K., Varoqueaux, F., & Brose, N. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601421200 · Cited by 103 · see citing works

Interactions between Piccolo and the Actin/Dynamin-binding Protein Abp1 Link Vesicle Endocytosis to Presynaptic Active Zones

Fenster, S. D., Kessels, M. M., Qualmann, B., Chung, W. J., Nash, J. E., Gundelfinger, E. D., & Garner, C. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210792200 · Cited by 103 · see citing works

Coupling actin and membrane dynamics during calcium-regulated exocytosis: a role for Rho and ARF GTPases

Bader, M. F., Doussau, F., Chasserot‐Golaz, S., Vitale, N., & Gasman, S. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2004.09.028 · Cited by 102 · see citing works

A conformational switch in the Piccolo C2A domain regulated by alternative splicing

Garcia, J. M., Gerber, S. H., Sugita, S., Südhof, T., & Rizo, J. (2004) · Nature Structural &Molecular Biology · doi:10.1038/nsmb707 · Cited by 105 · see citing works

Prenylated Rab Acceptor Protein Is a Receptor for Prenylated Small GTPases

Figueroa‐Romero, C., Taylor, J., & Vojtek, A. B. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101763200 · Cited by 97 · see citing works

A protein interaction node at the neurotransmitter release site: Domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1

Wang, X., Hu, B., Zieba, A., Neumann, N. G., Kasper-Sonnenberg, M., Honsbein, A., Hultqvist, G., Conze, T., Witt, W., Limbach, C., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1255-09.2009 · Cited by 96 · see citing works

Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site

Limbach, C., Laue, M. M., Wang, X., Hu, B., Thiede, N., Hultqvist, G., & Kilimann, M. W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101707108 · Cited by 92 · see citing works

Cellular Mechanisms for the Biogenesis and Transport of Synaptic and Dense-Core Vesicles

Gondré‐Lewis, M. C., Park, J. J., & Loh, Y. P. (2012) · International review of cytology · doi:10.1016/b978-0-12-394310-1.00002-3 · Cited by 91 · see citing works

LAR, liprin α and the regulation of active zone morphogenesis

Stryker, E., & Johnson, K. G. (2007) · Journal of Cell Science · doi:10.1242/jcs.03491 · Cited by 90 · see citing works

Amyotrophic lateral sclerosis, gene deregulation in the anterior horn of the spinal cord and frontal cortex area 8: implications in frontotemporal lobar degeneration

Andrés‐Benito, P., Moreno, J. R., Aso, E., Povedano, M., & Ferrer, I. (2017) · Aging · doi:10.18632/aging.101195 · Cited by 89 · see citing works

CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST

Deguchi‐Tawarada, M., Inoue, E., Takao‐Rikitsu, E., Inoue, M., Ohtsuka, T., & Takai, Y. (2004) · Genes to Cells · doi:10.1111/j.1356-9597.2004.00697.x · Cited by 89 · see citing works

A New Component in Synaptic Plasticity: Upregulation of Kinesin in the Neurons of the Gill-Withdrawal Reflex

Puthanveettil, S. V., Monje, F. J., Miniaci, M. C., Choi, Y., Karl, K. A., Khandros, E., Gawinowicz, M. A., Sheetz, M. P., & Kandel, E. R. (2008) · Cell · doi:10.1016/j.cell.2008.11.003 · Cited by 88 · see citing works

The role of laminins in the organization and function of neuromuscular junctions

Rogers, R. S., & Nishimune, H. (2016) · Matrix Biology · doi:10.1016/j.matbio.2016.08.008 · Cited by 87 · see citing works

Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology

Longhena, F., Faustini, G., Spillantini, M. G., & Bellucci, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20010141 · Cited by 87 · see citing works

Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo

Ivanova, D., Dirks, A., Montenegro‐Venegas, C., Schöne, C., Altrock, W. D., Marini, C., Frischknecht, R., Schanze, D., Zenker, M., Gundelfinger, E. D., et al. (2015) · The EMBO Journal · doi:10.15252/embj.201488796 · Cited by 86 · see citing works

Short-distance vesicle transport via phase separation

Qiu, H., Wu, X., Ma, X., Li, S., Cai, Q., Ganzella, M., Ge, L., Zhang, H., & Zhang, M. (2024) · Cell · doi:10.1016/j.cell.2024.03.003 · Cited by 86 · see citing works

Piccolo Regulates the Dynamic Assembly of Presynaptic F-Actin

Waites, C. L., Leal‐Ortiz, S., Andlauer, T. F. M., Sigrist, S. J., & Garner, C. C. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1835-11.2011 · Cited by 85 · see citing works

Sustaining rapid vesicular release at active zones: potential roles for vesicle tethering

Hallermann, S., & Silver, R. A. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.10.001 · Cited by 83 · see citing works

Identification and Immunocytochemical Characterization of Piccolino, a Novel Piccolo Splice Variant Selectively Expressed at Sensory Ribbon Synapses of the Eye and Ear

Regus‐Leidig, H., Ott, C., Löhner, M., Atorf, J., Fuchs, M., Sedmak, T., Kremers, J., Fejtová, A., Gundelfinger, E. D., & Brandstätter, J. H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070373 · Cited by 82 · see citing works

Synaptic organization in cochlear inner hair cells deficient for the CaV1.3 (α1D) subunit of L-type Ca2+ channels

N., R. M. N., Bulankina, A. V., Khimich, D., Giese, A., & Moser, T. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.05.057 · Cited by 79 · see citing works

Molecular Genetic Findings in Suicidal Behavior: What is Beyond the Serotonergic System?

Rujescu, D., Thalmeier, A., Möller, H., Bronisch, T., & Giegling, I. (2006) · Archives of Suicide Research · doi:10.1080/13811110600897317 · Cited by 79 · see citing works

PRA Isoforms Are Targeted to Distinct Membrane Compartments

Abdul‐Ghani, M., Gougeon, P., Prosser, D. C., DaSilva, L. F., & Ngsee, J. K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009073200 · Cited by 79 · see citing works

CAST and ELKS proteins: structural and functional determinants of the presynaptic active zone

Hida, Y., & Ohtsuka, T. (2010) · The Journal of Biochemistry · doi:10.1093/jb/mvq065 · Cited by 78 · see citing works

Intra-axonal Synthesis of SNAP25 Is Required for the Formation of Presynaptic Terminals

Batista, A. F. R., Martínez, J. C., & Hengst, U. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.08.097 · Cited by 78 · see citing works

Coupling exo- and endocytosis: An essential role for PIP2 at the synapse

Koch, M., & Holt, M. G. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2012.02.008 · Cited by 76 · see citing works

Active zone density is conserved during synaptic growth but impaired in aged mice

Chen, J., Mizushige, T., & Nishimune, H. (2011) · The Journal of Comparative Neurology · doi:10.1002/cne.22764 · Cited by 76 · see citing works

Ribbon Synapses and Visual Processing in the Retina

Lagnado, L., & Schmitz, F. (2015) · Annual Review of Vision Science · doi:10.1146/annurev-vision-082114-035709 · Cited by 73 · see citing works

The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release

Tobin, V. A., Leng, G., & Ludwig, M. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00261 · Cited by 70 · see citing works

Proteome-wide characterization of signalling interactions in the hippocampal CA4/DG subfield of patients with Alzheimer’s disease

Kim, J. H., Franck, J., Kang, T., Heinsen, H., Ravid, R., Ferrer, I., Cheon, M. H., Lee, J., Yoo, J. S., Steinbusch, H. W. M., et al. (2015) · Scientific Reports · doi:10.1038/srep11138 · Cited by 68 · see citing works

The Yip1p·Yif1p Complex Is Required for the Fusion Competence of Endoplasmic Reticulum-derived Vesicles

Barrowman, J., Wang, W., Zhang, Y., & Ferro‐Novick, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302406200 · Cited by 67 · see citing works

Exchange and Redistribution Dynamics of the Cytoskeleton of the Active Zone Molecule Bassoon

Tsuriel, S., Fisher-Lavie, A., Wittenmayer, N., Dresbach, T., Garner, C. C., & Ziv, N. E. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4777-08.2009 · Cited by 66 · see citing works

Loss of PCLO function underlies pontocerebellar hypoplasia type III

Ahmed, M. Y., Chioza, B. A., Rajab, A., Schmitz‐Abe, K., Al‐Khayat, A., Al-Turki, S., Baple, E. L., Patton, M. A., Al‐Memar, A., Hurles, M. E., et al. (2015) · Neurology · doi:10.1212/wnl.0000000000001523 · Cited by 66 · see citing works

Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice

Nishimune, H., Badawi, Y., Mori, S., & Shigemoto, K. (2016) · Scientific Reports · doi:10.1038/srep27935 · Cited by 66 · see citing works

Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone

Gundelfinger, E. D., Reissner, C., & Garner, C. C. (2016) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2015.00019 · Cited by 203 · see citing works

Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix.

Cases-Langhoff, C., Voss, B., Garner, A. M., APPELTAUER, U., Takei, K., Kindler, S., Veh, R. W., Camilli, P. V. D., Gundelfinger, E. D., & Garner, C. C. (1996) · PubMed · Cited by 176 · see citing works

Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: Comparison with Bassoon

Dick, O., Hack, I., Altrock, W. D., Garner, C. C., Gundelfinger, E. D., & Brandstätter, J. H. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1344 · Cited by 153 · see citing works

Piccolo and Bassoon

Juranek, J. K., & Mukherjee, K. (2009) · Elsevier eBooks · doi:10.1016/b978-008045046-9.01360-7

Interactions between Piccolo and the Actin/Dynamin-binding Protein Abp1 Link Vesicle Endocytosis to Presynaptic Active Zones

Fenster, S. D., Kessels, M. M., Qualmann, B., Chung, W. J., Nash, J. E., Gundelfinger, E. D., & Garner, C. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210792200 · Cited by 103 · see citing works