A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

Raiborg, C., & Stenmark, H. (2009) · Nature · doi:10.1038/nature07961 · Cited by 1,359

Receptor downregulation and multivesicular-body sorting

Katzmann, D. J., Odorizzi, G., & Emr, S. D. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm973 · Cited by 1,201

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

Haglund, K., Sigismund, S., Polo, S., Szymkiewicz, I., Di Fiore, P. P., & Dikic, I. (2003) · Nature Cell Biology · doi:10.1038/ncb983 · Cited by 715

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.

Bienko, M., Green, C. M., Crosetto, N., Rudolf, F., Zapart, G., Coull, B., Kannouche, P., Wider, G., Peter, M., Lehmann, A. R., et al. (2005) · Science · doi:10.1126/science.1120615 · Cited by 712

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

Raiborg, C., Bache, K. G., Gillooly, D. J., Madshus, I. H., Stang, E., & Stenmark, H. (2002) · Nature Cell Biology · doi:10.1038/ncb791 · Cited by 652

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

Polo, S., Sigismund, S., Faretta, M., Guidi, M., Capua, M. R., Bossi, G., Chen, H., De Camilli, P., & Di Fiore, P. P. (2002) · Nature · doi:10.1038/416451a · Cited by 571

THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network

Hurley, J. H., & Emr, S. D. (2006) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.35.040405.102126 · Cited by 546

Hrs Regulates Endosome Membrane Invagination and Tyrosine Kinase Receptor Signaling in Drosophila

Lloyd, T. E., Atkinson, R., Wu, M. N., Zhou, Y., Pennetta, G., & Bellen, H. J. (2002) · Cell · doi:10.1016/s0092-8674(02)00611-6 · Cited by 401

Distinct monoubiquitin signals in receptor endocytosis

Haglund, K. (2003) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2003.09.005 · Cited by 367

PLIC proteins or ubiquilins regulate autophagy‐dependent cell survival during nutrient starvation

N'Diaye, E., Kajihara, K. K., Hsieh, I., Morisaki, H., Debnath, J., & Brown, E. J. (2009) · The EMBO Reports · doi:10.1038/embor.2008.238 · Cited by 323

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

Mosesson, Y., Shtiegman, K., Katz, M., Zwang, Y., Vereb, G., Szollosi, J., & Yarden, Y. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c300096200 · Cited by 286

E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation

d'Azzo, A., Bongiovanni, A., & Nastasi, T. (2005) · Traffic · doi:10.1111/j.1600-0854.2005.00294.x · Cited by 206

NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control

Wang, B., Hurov, K., Hofmann, K., & Elledge, S. J. (2009) · Genes & Development · doi:10.1101/gad.1770309 · Cited by 172

Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage‐induced 53BP1 foci at G1/G2 cell‐cycle phases

Wakeman, T. P., Wang, Q., Feng, J., & Wang, X. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.50 · Cited by 113

SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomes

Norris, A., Tammineni, P., Wang, S., Gerdes, J., Murr, A., Kwan, K. Y., Cai, Q., & Grant, B. D. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1612730114 · Cited by 90

Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation

Kanazawa, C., Morita, E., Yamada, M., Ishii, N., Miura, S., Asao, H., Yoshimori, T., & Sugamura, K. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.08.078 · Cited by 68

A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia

Lange, S. M., Bennett, J. A., Eisert, R. J., & Brown, A. (2025) · Cell · doi:10.1016/j.cell.2025.07.043 · Cited by 11

Promiscuous and multivalent interactions between Eps15 and partner protein Dab2 generate a complex interaction network

Papagiannoula, A., Vedel, I. M., Motzny, K., Tengo, M., Saiti, A., & Milles, S. (2025) · Nature Communications · doi:10.1038/s41467-025-63090-1 · Cited by 8