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Functional neurological disorder: new subtypes and shared mechanisms
Open accessAbstract
Functional neurological disorder is common in neurological practice. A new approach to the positive diagnosis of this disorder focuses on recognisable patterns of genuinely experienced symptoms and signs that show variability within the same task and between different tasks over time. Psychological stressors are common risk factors for functional neurological disorder, but are often absent. Four entities-functional seizures, functional movement disorders, persistent perceptual postural dizziness, and functional cognitive disorder-show similarities in aetiology and pathophysiology and are variants of a disorder at the interface between neurology and psychiatry. All four entities have distinctive features and can be diagnosed with the support of clinical neurophysiological studies and other biomarkers. The pathophysiology of functional neurological disorder includes overactivity of the limbic system, the development of an internal symptom model as part of a predictive coding framework, and dysfunction of brain networks that gives movement the sense of voluntariness. Evidence supports tailored multidisciplinary treatment that can involve physical and psychological therapy approaches.
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“Early adverse life experiences, negative affectivity, neuroticism, depression, and anxiety have been identified as psycho logical predisposing conditions for persistent physical symptoms”
From Persistent physical symptoms: definition, genesis, and management (2024) · cites this paper as [69]
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“Common biomedical factors, such as persistent inflammation and dysregulation of the immune, autonomic, metabolic, and microbiome systems, as well as genetic and epigenetic factors, can cause somatic symptoms to persist or intensify”
From Persistent physical symptoms: definition, genesis, and management (2024) · cites this paper as [69]
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Cites
LaFrance, W. C., Baker, G. A., Duncan, R., Goldstein, L. H., & Reuber, M. (2013) · Epilepsia · doi:10.1111/epi.12356 · Cited by 856
Staab, J. P., Eckhardt-Henn, A., Horii, A., Jacob, R., Strupp, M., Brandt, T., & Bronstein, A. (2017) · Journal of Vestibular Research · doi:10.3233/ves-170622 · Cited by 840
Self-citationCurrent Concepts in Diagnosis and Treatment of Functional Neurological Disorders
Espay, A. J., Aybek, S., Carson, A., Edwards, M. J., Goldstein, L. H., Hallett, M., LaFaver, K., LaFrance, W. C., Lang, A. E., Nicholson, T., et al. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2018.1264 · Cited by 786
Self-citationHobbs, R. F., Bankhead, C. R., Mukhtar, T. K., Stevens, S., Perera, R., Holt, T., & Salisbury, C. (2016) · The Lancet · doi:10.1016/s0140-6736(16)00620-6 · Cited by 609
Symptoms and the body: taking the inferential leap
Van den Bergh, O., Witthöft, M., Petersen, S., & Brown, R. J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.015 · Cited by 543
Ludwig, L., Pasman, J. A., Nicholson, T., Aybek, S., David, A. S., Tuck, S., Kanaan, R. A., Roelofs, K., Carson, A., & Stone, J. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30051-8 · Cited by 495
Self-citationPsychogenic movement disorders
Gupta, A., & Lang, A. E. (2009) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32832dc169 · Cited by 440
The involuntary nature of conversion disorder
Voon, V., Gallea, C., Hattori, N., Bruno, M., Ekanayake, V., & Hallett, M. (2010) · Neurology · doi:10.1212/wnl.0b013e3181ca00e9 · Cited by 335
Self-citationGoldstein, L. H., Robinson, E. J., Mellers, J. D. C., Stone, J., Carson, A., Reuber, M., Medford, N., McCrone, P., Murray, J., Richardson, M. P., et al. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30128-0 · Cited by 287
Self-citationTowards an integrative theory of psychogenic non-epileptic seizures (PNES)
Brown, R. J., & Reuber, M. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2016.06.003 · Cited by 279
Brown, R. J., & Reuber, M. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2016.01.003 · Cited by 276
Randomised feasibility study of physiotherapy for patients with functional motor symptoms
Nielsen, G., Buszewicz, M., Stevenson, F., Hunter, R., Holt, K., Dudziec, M., Ricciardi, L., Marsden, J., Joyce, E., & Edwards, M. (2017) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2016-314408 · Cited by 246
Teodoro, T., Edwards, M. J., & Isaacs, J. D. (2018) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2017-317823 · Cited by 241
Functional cognitive disorders: a systematic review
McWhirter, L., Ritchie, C., Stone, J., & Carson, A. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30405-5 · Cited by 240
Self-citationMotor inhibition in hysterical conversion paralysis
Cojan, Y., Waber, L., Carruzzo, A., & Vuilleumier, P. O. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.023 · Cited by 237
Duncan, R., Razvi, S., & Mulhern, S. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.10.022 · Cited by 226
Neuroimaging in functional neurological disorder: State of the field and research agenda
Perez, D. L., Nicholson, T. R., Asadi-Pooya, A. A., Bègue, I., Butler, M., Carson, A. J., David, A. S., Deeley, Q., Diez, I., Edwards, M. J., et al. (2021) · NeuroImage: Clinical · doi:10.1016/j.nicl.2021.102623 · Cited by 216
Self-citationPsychopathology and psychogenic movement disorders
Kranick, S. M., Ekanayake, V., Martinez, V., Ameli, R., Hallett, M., & Voon, V. (2011) · Movement Disorders · doi:10.1002/mds.23830 · Cited by 207
Self-citationKutlubaev, M. A., Xu, Y., Hackett, M. L., & Stone, J. (2018) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2018.10.010 · Cited by 205
Self-citationFunctional cognitive disorder: dementia’s blind spot
Ball, H. A., McWhirter, L., Ballard, C., Bhome, R., Blackburn, D. J., Edwards, M. J., Fleming, S. M., Fox, N. C., Howard, R., Huntley, J., et al. (2020) · Brain · doi:10.1093/brain/awaa224 · Cited by 203
Self-citationCarson, A. J., & Lehn, A. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00005-9 · Cited by 201
Stephen, C. D., Fung, V., Lungu, C. I., & Espay, A. J. (2021) · JAMA Neurology · doi:10.1001/jamaneurol.2020.3753 · Cited by 187
Kanemoto, K., LaFrance, W. C., Jr., Duncan, R., Gigineishvili, D., Park, S.-P., Tadokoro, Y., Ikeda, H., Paul, R., Zhou, D., Taniguchi, G., et al. (2017) · Epilepsia Open · doi:10.1002/epi4.12060 · Cited by 170
Management of functional neurological disorder
Gilmour, G. S., Nielsen, G., Teodoro, T., Yogarajah, M., Coebergh, J. A., Dilley, M. D., Martino, D., & Edwards, M. J. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09772-w · Cited by 169
Pathogenesis and pathophysiology of functional (psychogenic) movement disorders
Baizabal-Carvallo, J. F., Hallett, M., & Jankovic, J. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.02.013 · Cited by 163
Self-citationPersistent Postural-Perceptual Dizziness
Staab, J. P. (2020) · Springer eBooks · doi:10.1007/978-3-032-18264-7_62 · Cited by 162
Self-citationOccupational therapy consensus recommendations for functional neurological disorder
Nicholson, C., Edwards, M. J., Carson, A. J., Gardiner, P., Golder, D., Hayward, K., Humblestone, S., Jinadu, H., Lumsden, C., MacLean, J., et al. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2019-322281 · Cited by 159
Self-citationPsychological interventions for psychogenic non-epileptic seizures: A meta-analysis
Carlson, P., & Perry, K. N. (2016) · Seizure · doi:10.1016/j.seizure.2016.12.007 · Cited by 156
Loss of sensory attenuation in patients with functional (psychogenic) movement disorders
Pareés, I., Brown, H., Nuruki, A., Adams, R. A., Davare, M., Bhatia, K. P., Friston, K., & Edwards, M. J. (2014) · Brain · doi:10.1093/brain/awu237 · Cited by 155
Tatum, W. O., Hirsch, L. J., Gelfand, M. A., Acton, E. K., LaFrance, W. C., Jr., Duckrow, R. B., Chen, D. K., Blum, A. S., Hixson, J., Drazkowski, J., et al. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2019.4785 · Cited by 155
Decade of progress in motor functional neurological disorder: Continuing the momentum
Perez, D. L., Edwards, M. J., Nielsen, G., Kozlowska, K., Hallett, M., & LaFrance, Jr. (2021) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-323953 · Cited by 149
Self-citationLee, J., Lee, E., Kim, J., Lee, Y., Jeong, Y., Choi, B. S., Kim, J., & Staab, J. P. (2018) · Human Brain Mapping · doi:10.1002/hbm.24080 · Cited by 143
Self-citationLidstone, S. C., Costa-Parke, M., Robinson, E. J., Ercoli, T., & Stone, J. (2022) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2021-328462 · Cited by 139
Self-citationSystematic review of psychotherapy for adults with functional neurological disorder
Gutkin, M., McLean, L., Brown, R. J., & Kanaan, R. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2019-321926 · Cited by 137
Frequency of a false positive diagnosis of epilepsy: A systematic review of observational studies
Xu, Y. H., Nguyen, D. C., Mohamed, A., Carcel, C., Li, Q., Kutlubaev, M. A., Anderson, C. S., & Hackett, M. L. (2016) · Seizure · doi:10.1016/j.seizure.2016.08.005 · Cited by 132
der Salm, S. M. A. V., Erro, R., Cordivari, C., Edwards, M. J., Koelman, J. H. T. M., van den Ende, T., Bhatia, K. P., van Rootselaar, A., Brown, P., & Tijssen, M. A. J. (2014) · Neurology · doi:10.1212/wnl.0000000000000982 · Cited by 131
Mortality in patients with psychogenic nonepileptic seizures
Nightscales, R., McCartney, L., Auvrez, C., Tao, G., Barnard, S. N., Malpas, C. B., Perucca, P., McIntosh, A. M., Chen, Z. Z., Sivathamboo, S., et al. (2020) · Neurology · doi:10.1212/wnl.0000000000009855 · Cited by 128
Bègue, I., Adams, C., Stone, J., & Perez, D. L. (2019) · NeuroImage: Clinical · doi:10.1016/j.nicl.2019.101798 · Cited by 124
Self-citationTics and functional tic-like movements: Can we tell them apart?
Ganos, C., Martino, D., Espay, A. J., Lang, A. E., Bhatia, K. P., & Edwards, M. J. (2019) · Neurology · doi:10.1212/wnl.0000000000008372 · Cited by 124
Interventions for subjective cognitive decline: systematic review and meta-analysis
Bhome, R., Berry, A. J., Huntley, J. D., & Howard, R. J. (2018) · BMJ Open · doi:10.1136/bmjopen-2018-021610 · Cited by 123
The Role of EEG in the Erroneous Diagnosis of Epilepsy
Amin, U., & Benbadis, S. R. (2019) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0000000000000572 · Cited by 122
Prognosis of functional neurologic disorders
Gelauff, J., & Stone, J. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00043-6 · Cited by 121
Self-citationExplanation as treatment for functional neurologic disorders
Stone, J., Carson, A. J., & Hallett, M. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00044-8 · Cited by 120
Self-citationHingray, C., El‐Hage, W., Duncan, R., Gigineishvili, D., Kanemoto, K., LaFrance, W. C., Jr., de Marinis, A., Paul, R., Pretorius, C., Téllez‐Zenteno, J. F., et al. (2017) · Epilepsia · doi:10.1111/epi.13952 · Cited by 120
Neurologists' understanding and management of conversion disorder
Kanaan, R., Armstrong, D., & Wessely, S. C. (2011) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2010.233114 · Cited by 110
Jones, B., Reuber, M., & Norman, P. (2016) · Epilepsia · doi:10.1111/epi.13268 · Cited by 110
Management of psychogenic non‐epileptic seizures: a multidisciplinary approach
Gasparini, S., Beghi, E., Ferlazzo, E., Beghi, M., Belcastro, V., Biermann, K. P., Bottini, G., Capovilla, G., Cervellione, R., Cianci, V., et al. (2018) · European Journal of Neurology · doi:10.1111/ene.13818 · Cited by 104
Vestibular Rehabilitation Therapy Outcomes in Patients With Persistent Postural-Perceptual Dizziness
Nada, E. H., Ibraheem, O. A., & Hassaan, M. R. (2019) · Annals of Otology Rhinology & Laryngology · doi:10.1177/0003489418823017 · Cited by 100
Incidence and outcome of functional stroke mimics admitted to a hyperacute stroke unit
Gargalas, S., Weeks, R., Khan-Bourne, N., Shotbolt, P., Simblett, S. K., Ashraf, L., Doyle, C., Bancroft, V., & David, A. S. (2015) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2015-311114 · Cited by 99
Clinical Correlates of Functional Motor Disorders: An Italian Multicenter Study
Tinazzi, M., Morgante, F., Marcuzzo, E., Erro, R., Barone, P., Ceravolo, R., Mazzucchi, S., Pilotto, A., Padovani, A., Romito, L. M., et al. (2020) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.13077 · Cited by 99
Věchetová, G., Slovák, M., Kemlink, D., Hanzlíková, Z., Dušek, P., Nikolai, T., Růžička, E., Edwards, M. J., & Serranová, T. (2018) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2018.10.001 · Cited by 98
Myers, L., Vaidya-Mathur, U., & Lancman, M. E. (2016) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.10.019 · Cited by 94
Performance validity test failure in clinical populations—a systematic review
McWhirter, L., Ritchie, C. W., Stone, J., & Carson, A. (2020) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-323776 · Cited by 92
Self-citationBaslet, G. C., Bajestan, S. N., Aybek, S., Modirrousta, M., D.Clin.Psy, J. P., Cavanna, A. E., Perez, D. L., Lazarow, S. S., Raynor, G., Voon, V., et al. (2020) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.19120354 · Cited by 90
Self-citationTinazzi, M., Geroin, C., Erro, R., Marcuzzo, E., Cuoco, S., Ceravolo, R., Mazzucchi, S., Pilotto, A., Padovani, A., Romito, L. M., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14674 · Cited by 86
Villagrán, A., Eldøen, G., Duncan, R., Aaberg, K. M., Hofoss, D., & Lossius, M. I. (2021) · Epilepsia · doi:10.1111/epi.16949 · Cited by 86
Characteristics of 698 patients with dissociative seizures: A UK multicenter study
Goldstein, L. H., Robinson, E. J., Reuber, M., Chalder, T., Callaghan, H., Eastwood, C., Landau, S., McCrone, P., Medford, N., Mellers, J. D. C., et al. (2019) · Epilepsia · doi:10.1111/epi.16350 · Cited by 84
Self-citationBiomarkers in the diagnosis and study of psychogenic nonepileptic seizures: A systematic review
Sundararajan, T., Tesar, G. E., & Jimenez, X. F. (2015) · Seizure · doi:10.1016/j.seizure.2015.12.011 · Cited by 82
Nonnekes, J. H., Růžička, E., Serranová, T., Reich, S. G., Bloem, B. R., & Hallett, M. (2020) · Neurology · doi:10.1212/wnl.0000000000009649 · Cited by 79
Self-citationBrain Correlates of Persistent Postural-Perceptual Dizziness: A Review of Neuroimaging Studies
Indovina, I., Passamonti, L., Mucci, V., Chiarella, G., Lacquaniti, F., & Staab, J. P. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10184274 · Cited by 77
Self-citationYu, Y., Xue, H., Zhang, Y., & Zhou, J. (2018) · BioMed Research International · doi:10.1155/2018/8518631 · Cited by 74
Functional symptoms in neurology: mimics and chameleons
Stone, J., Reuber, M., & Carson, A. (2013) · Practical Neurology · doi:10.1136/practneurol-2012-000422 · Cited by 72
Self-citationThe safety of antiepileptic drug withdrawal in patients with non-epileptic seizures
Oto, M. (2005) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2005.064063 · Cited by 70
Gender Differences in Functional Movement Disorders
Baizabal‐Carvallo, J. F., & Jankovic, J. J. (2019) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.12864 · Cited by 67
Functional Motor Symptoms in Parkinson’s Disease and Functional Parkinsonism: A Systematic Review
Akkaoui, M. A., Geoffroy, P. A., Roze, E. F., Degos, B., & Garcin, B. (2019) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.19030058 · Cited by 63
Nigro, S. L., Indovina, I., Riccelli, R., Chiarella, G., Petrolo, C., Lacquaniti, F., Staab, J. P., & Passamonti, L. (2018) · Brain Imaging and Behavior · doi:10.1007/s11682-018-9900-6 · Cited by 62
Self-citationSpagnolo, P. A., Norato, G., Maurer, C. W., Goldman, D., Hodgkinson, C., Horovitz, S., & Hallett, M. (2020) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2019-322636 · Cited by 62
Self-citationStigma and functional neurological disorder: a research agenda targeting the clinical encounter
MacDuffie, K. E., Grubbs, L., Best, T., LaRoche, S. M., Mildon, B., Myers, L., Stafford, E. M., & Rommelfanger, K. S. (2020) · CNS Spectrums · doi:10.1017/s1092852920002084 · Cited by 60
The Immunogenicity of the C Fragment of Tetanus Neurotoxin in Production of Tetanus Antitoxin
Yu, R., Ji, C., Xu, J., Wang, D., Fang, T., Jing, Y., Shen, C. K.-F., & Chen, W. (2018) · BioMed Research International · doi:10.1155/2018/6057348 · Cited by 58
Functional Dystonia: Differentiation From Primary Dystonia and Multidisciplinary Treatments
Frucht, L., Perez, D. L., Callahan, J., MacLean, J., Song, P. C., Sharma, N., & Stephen, C. D. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2020.605262 · Cited by 58
The misdiagnosis of functional disorders as other neurological conditions
Walzl, D., Carson, A. J., & Stone, J. (2019) · Journal of Neurology · doi:10.1007/s00415-019-09356-3 · Cited by 53
Self-citationMachine learning as a diagnostic decision aid for patients with transient loss of consciousness
Wardrope, A., Jamnadas-Khoda, J., Broadhurst, M., Grünewald, R. A., Heaton, T., Howell, S. J., Koepp, M. J., Parry, S. W., Sisodiya, S. M., Walker, M. C., et al. (2020) · Neurology Clinical Practice · doi:10.1212/cpj.0000000000000726 · Cited by 52
Metacognition in functional cognitive disorder- a potential mechanism and treatment target
Bhome, R., McWilliams, A., Huntley, J. D., Fleming, S. M., & Howard, R. J. (2019) · Cognitive Neuropsychiatry · doi:10.1080/13546805.2019.1651708 · Cited by 48
Reduced drift rate: a biomarker of impaired information processing in functional movement disorders
Sadnicka, A., Daum, C., Meppelink, A.-M., Manohar, S., & Edwards, M. J. (2019) · Brain · doi:10.1093/brain/awz387 · Cited by 48
Apazoglou, K., Adouan, W., Aubry, J., Dayer, A. G., & Aybek, S. (2017) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2017-316469 · Cited by 47
Self-citationA physical therapy programme for functional motor symptoms: A telemedicine pilot study
Demartini, B., Bombieri, F., Goeta, D., Gambini, O., Ricciardi, L., & Tinazzi, M. (2019) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2019.05.004 · Cited by 47
Bhome, R., Huntley, J. D., Price, G., & Howard, R. J. (2019) · Cognitive Neuropsychiatry · doi:10.1080/13546805.2019.1590190 · Cited by 45
Kuwabara, J., Kondo, M., Kabaya, K., Watanabe, W., Shiraishi, N., Sakai, M., Toshishige, Y., Ino, K., Nakayama, M., Iwasaki, S., et al. (2020) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2020.102609 · Cited by 45
Biomarkers in functional movement disorders: a systematic review
Thomsen, B. L. C., Teodoro, T., & Edwards, M. J. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-323141 · Cited by 45
Outcome of ambulatory video-EEG monitoring in a ˜10,000 patient nationwide cohort
Syed, T. U., LaFrance, W. C., Jr., Loddenkemper, T., Benbadis, S. R., Slater, J. D., Atrache, R. E., Albunni, H. N., Khan, M. T., Aziz, S., Ali, N. Y., et al. (2019) · Seizure · doi:10.1016/j.seizure.2019.01.018 · Cited by 42
Functional networks of motor inhibition in conversion disorder patients and feigning subjects
Hassa, T., de Jel, E., Tüscher, O., Schmidt, R., & Schoenfeld, M. A. (2016) · NeuroImage Clinical · doi:10.1016/j.nicl.2016.05.009 · Cited by 41
Jenkins, L., Cosgrove, J., Chappell, P., Kheder, A., Sokhi, D. S., & Reuber, M. (2016) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.08.008 · Cited by 41
Reuber, M., Blackburn, D. J., Elsey, C., Wakefield, S., Ardern, K., Harkness, K., Venneri, A., Jones, D., Shaw, C. B., & Drew, P. (2018) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000231 · Cited by 41
Indranada, A. M., Mullen, S. A., Duncan, R., Berlowitz, D. J., & Kanaan, R. (2018) · Seizure · doi:10.1016/j.seizure.2018.05.007 · Cited by 41
Psychogenic movement disorders in children and adolescents: an update
Harris, S. R. (2019) · European Journal of Pediatrics · doi:10.1007/s00431-019-03317-8 · Cited by 41
Internet-based self-help randomized trial for motor functional neurologic disorder (SHIFT)
Gelauff, J., Rosmalen, J. G. M., Carson, A. J., Dijk, J. M., Ekkel, M., Nielsen, G., Stone, J., & Tijssen, M. A. J. (2020) · Neurology · doi:10.1212/wnl.0000000000010381 · Cited by 41
Self-citationImpaired resting vagal tone in patients with functional movement disorders
Maurer, C. W., Liu, V. D., LaFaver, K., Ameli, R., Wu, T., Toledo, R., Epstein, S. A., & Hallett, M. (2016) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2016.06.009 · Cited by 38
Self-citationFactitious disorders and malingering in relation to functional neurologic disorders
Bass, C., & Halligan, P. W. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00042-4 · Cited by 38
Dreissen, Y. E. M., Dijk, J. M., Gelauff, J., Zoons, E., van Poppelen, D., Contarino, M. F., Zutt, R., Post, B., Munts, A. G., Speelman, J. D., et al. (2019) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-320071 · Cited by 38
Gender as a Risk Factor for Functional Movement Disorders: The Role of Sexual Abuse
Kletenik, I., Sillau, S., Attaripour, S., LaFaver, K., Hallett, M., & Berman, B. D. (2019) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.12863 · Cited by 37
Self-citationMisdirected attentional focus in functional tremor
Huys, A.-C. M. L., Haggard, P., Bhatia, K. P., & Edwards, M. J. (2021) · Brain · doi:10.1093/brain/awab230 · Cited by 37
Pain processing in functional and idiopathic dystonia: An exploratory study
Morgante, F., Matinella, A., Andrenelli, E., Ricciardi, L., Allegra, C., Terranova, C., Girlanda, P., & Tinazzi, M. (2018) · Movement Disorders · doi:10.1002/mds.27402 · Cited by 35
Gilmour, G. S., MacIsaac, R., Subotic, A., Wiebe, S., & Josephson, C. B. (2021) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2021.108030 · Cited by 34
Peterson, K. T., Kosior, R. K., Meek, B. P., Ng, M., Perez, D. L., & Modirrousta, M. (2018) · Psychosomatics · doi:10.1016/j.psym.2018.03.001 · Cited by 31
Functional or not functional; that’s the question
Lagrand, T. J., Tuitert, I., Klamer, M. R., van der Meulen, A., van der Palen, J. A. M., Kramer, G., & Tijssen, M. A. J. (2020) · European Journal of Neurology · doi:10.1111/ene.14488 · Cited by 31
Functional jerks, tics, and paroxysmal movement disorders
Dreissen, Y. E. M., Cath, D. C., & Tijssen, M. A. J. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00021-7 · Cited by 30
Functional (psychogenic) stereotypies
Baizabal‐Carvallo, J. F., & Jankovic, J. J. (2017) · Journal of Neurology · doi:10.1007/s00415-017-8551-7 · Cited by 29
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Kramer, G., van der Stouwe, A. M. M., Maurits, N. M., Tijssen, M. A. J., & Elting, J. W. J. (2017) · Clinical Neurophysiology · doi:10.1016/j.clinph.2017.10.002 · Cited by 29
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Teodoro, T., Koreki, A., Meppelink, A. M., Little, S. J., Nielsen, G., Macerollo, A., Ferreira, J. J., Pareés, I., Lang, A. E., & Edwards, M. J. (2020) · European Journal of Neurology · doi:10.1111/ene.14189 · Cited by 27
Gledhill, J. M., Brand, E. J., Pollard, J. R., Clair, R. D. S., Wallach, T. M., & Crino, P. B. (2021) · Neurology · doi:10.1212/wnl.0000000000011552 · Cited by 27
Pick, S., Hodsoll, J. P., Stanton, B. R., Eskander, A., Stavropoulos, I., Samra, K., Bottini, J., Ahmad, H., David, A. S., Purves, A., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-037198 · Cited by 26
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Schmidt, T., Ebersbach, G., Oelsner, H., Sprock, A., König, I. R., Bäumer, T., Münchau, A. M., & Weißbach, A. (2021) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.13268 · Cited by 26
Foroughi, A. A., Nazeri, M., & Asadi‐Pooya, A. A. (2020) · Seizure · doi:10.1016/j.seizure.2020.08.024 · Cited by 25
Wurthmann, S., Holle, D., Obermann, M., Roesner, M., Nsaka, M., Scheffler, A., Kleinschnitz, C., & Naegel, S. (2021) · BMC Neurology · doi:10.1186/s12883-021-02417-z · Cited by 25
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Prepulse inhibition of the blink reflex is abnormal in functional movement disorders
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Stone, J., Hoeritzauer, I., Tesolin, L., & Carson, A. J. (2018) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2018.09.031 · Cited by 22
Self-citationWatson, C., Sivaswamy, L., Agarwal, R. R., Du, W., & Agarwal, R. L. (2019) · Journal of Child Neurology · doi:10.1177/0883073819830193 · Cited by 22
Zanzmera, P., Sharma, A., Bhatt, K., Patel, T. C., Luhar, M., Modi, A., & Jani, V. (2019) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2019.03.034 · Cited by 22
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Stone, J. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00003-5 · Cited by 18
Self-citationKusmakar, S., Karmakar, C. K., Yan, B., Muthuganapathy, R., Kwan, P., O'Brien, T. J., & Palaniswami, M. S. (2018) · Epilepsia · doi:10.1111/epi.14619 · Cited by 18
Nováková, B., Harris, P. R., Rawlings, G. H., & Reuber, M. (2019) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2019.03.002 · Cited by 17
Wardrope, A., Wong, S., McLaughlan, J., Wolfe, M., Oto, M., & Reuber, M. (2020) · Epilepsia · doi:10.1111/epi.16471 · Cited by 17
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Fend, M., Williams, L., Carson, A. J., & Stone, J. (2020) · Brain · doi:10.1093/brain/awaa037 · Cited by 15
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Williamson, J. C., & Larner, A. J. (2018) · International Psychogeriatrics · doi:10.1017/s1041610218000121 · Cited by 12
Husain, A. M., Towne, A. R., Chen, D. K., Whitmire, L., Voyles, S. R., & Cardenas, D. (2020) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0000000000000703 · Cited by 12
Suggestive seizure induction for inpatients with suspected psychogenic nonepileptic seizures
Popkirov, S., Grönheit, W., Jungilligens, J., Wehner, T., Schlegel, U., & Wellmer, J. (2020) · Epilepsia · doi:10.1111/epi.16629 · Cited by 12
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Gender Disparity and Abuse in Functional Movement Disorders: a multi-center case-control study
Kletenik, I., Holden, S., Sillau, S. H., O'Connell, N., MacGillivray, L., Mack, J., Haddock, B., Dirac, M., David, A., Nicholson, T., et al. (2022) · Journal of Neurology · doi:10.1007/s00415-021-10943-6 · Cited by 9
Self-citationTeaching Video NeuroImages: Foix-Chavany-Marie syndrome
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Stone, J. (2019) · Brain · doi:10.1093/brain/awz420 · Cited by 3
Self-citation
Research works printed but not linked: 2
- Sundararajan, 2016, Biomarkers in the diagnosis and study of psychogenic nonepileptic seizures: a systematic review, Seizure, 35, 11, 10.1016/j.seizure.2015.12.011 · DOI
- Gilmour, 2021, Inpatient treatment of functional neurological disorder: a scoping review, Can J Neurol Sci, 48, 204, 10.1017/cjn.2020.159 · DOI
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Metadata
- Authors
- Hallett, M., Aybek, S., Dworetzky, B. A., McWhirter, L., Staab, J. P., & Stone, J.
- Affiliations
- National Institutes of Health (US)
- University Hospital of Bern (CH)
- Brigham and Women's Hospital (US)
- University of Edinburgh (GB)
- Mayo Clinic (US)
- Corresponding author
- Hallett, Mark
- Venue
- The Lancet Neurology
- Publisher
- Elsevier BV
- Published
- 2022-06
- Volume
- 21
- Issue
- 6
- Pages
- 537-550
- ISSN
- 1474-4422 (ISSN-L)
- PMC
- PMC9107510
- OpenAlex
- W4223971211
- Cited by
- 538
- References
- 128
- Citations by year
- 2026: 154 · 2025: 159 · 2024: 126 · 2023: 81 · 2022: 17
- FWCI
- 16.48
- Type
- journal article
- Language
- en
- Update notices
- erratum (2022-06-01)
- Open access
- bronze
- doi.org
- Licence
- Locations
- The Lancet Neurology (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Bern Open Repository and Information System (University of Bern) (submittedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, cc-by)
- Funders
- National Institute of Neurological Disorders and Stroke
- U.S. Army Medical Research and Development Command
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (PP00P3_176985)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Keywords
- conversion disorder, psychogenic non-epileptic seizures, functional movement disorders, functional cognitive disorder, psychological stress, predictive coding, brain network dysfunction, neurophysiological markers, multidisciplinary treatment
- MeSH terms
- Brain, Conversion Disorder, Humans, Seizures
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