One-year follow-up results of a randomized controlled clinical trial on internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years
Open accessAbstract
Background: Internet-based cognitive behaviour therapy (CBT) is a promising new approach for the treatment of depressive symptoms. The current study had two aims: (1) to determine whether, after 1 year, an internet-based CBT intervention was more effective than a waiting-list control group; and (2) to determine whether the effect of the internet-based CBT differed from the group CBT intervention, 1 year after the start of treatment. Method: A total of 191 women and 110 men (mean age=55 years, s.d.=4.6) with subthreshold depression were randomized into internet-based treatment, group CBT (Lewinsohn's Coping with Depression Course), or a waiting-list control condition. The main outcome measure was treatment response after 1 year, defined as the difference in pretreatment and follow-up scores on the Beck Depression Inventory (BDI). Missing data were imputed using the multiple imputation procedure of data augmentation. Analyses were performed using multiple imputation inference. Results: In the waiting-list control group, we found a pretreatment to follow-up improvement effect size of 0.69, which was 0.62 in the group CBT condition and 1.22 with the internet-based treatment condition. Simple contrasts showed a significant difference between the waiting-list condition and internet-based treatment (p=0.03) and no difference between both treatment conditions (p=0.08). Conclusions: People aged over 50 years with subthreshold depression can still benefit from internet-based CBT 1 year after the start of treatment.
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- Authors
- Spek, V., Cuijpers, P., Nyklíček, I., Smits, N., Riper, H., Keyzer, J., & Pop, V.
- Affiliations
- Tilburg University (NL)
- Vrije Universiteit Amsterdam (NL)
- Trimbos Institute (NL)
- Corresponding author
- Spek, V.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2008-01-21
- Volume
- 38
- Issue
- 5
- Pages
- 635-639
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2018997673
- Cited by
- 139
- References
- 17
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 5 · 2023: 1 · 2022: 4 · 2021: 5 · 2020: 11 · 2019: 8 · 2018: 7 · 2017: 10 · 2016: 9 · 2015: 8 · 2014: 9 · 2013: 11 · 2012: 6
- FWCI
- 16.39
- Type
- journal article
- Language
- en
- Open access
- green
- research.vu.nl
- Licence
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- VU Research Portal (publishedVersion, other-oa)
- Research portal (Tilburg University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- internet-based cognitive behavioral therapy, subthreshold depression, geriatric depression, older adults, group cognitive behavioral therapy, long-term treatment outcomes, waitlist control, Beck Depression Inventory
- MeSH terms
- Adaptation, Psychological, Aged, Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Middle Aged, Personality Inventory, Therapy, Computer-Assisted, Cognitive Behavioral Therapy, Internet
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