Gray matter characteristics associated with trait anxiety in older adults are moderated by depression
Open accessAbstract
BACKGROUND: Structural gray matter characteristics of anxiety remain unclear. The aim of this study was to assess the influence of current depressive symptoms and history of depression on the gray matter characteristics of trait anxiety. METHODS: Structural magnetic resonance imaging (MRI) data from 393 individuals aged 65 years or older were used. Regions of interest (ROIs) included the amygdala, anterior cingulate cortex (ACC), insula, orbitofrontal cortex (OFC), and temporal cortex. Trait anxiety was measured by the State-Trait Anxiety Inventory (STAI). Depression and depressive symptoms were measured using DSM-IV criteria and the Center for Epidemiological Studies Depression Scale (CESD). RESULTS: After adjustments for sociodemographics and health-related variables, anxiety had a significant influence on the gray matter characteristics in all cortical ROIs. First, in participants without depression antecedents, higher trait anxiety was associated with a larger cortical thickness in all cortical ROIs. Second, in participants with a previous history of depression, higher trait anxiety was associated with a smaller cortical thickness in all cortical ROIs. CONCLUSIONS: These results suggest that anxiety is related to cortical thickness differently in healthy older adults and in older adults with psychiatric antecedents. Anxiety associated with thinner cortical areas could reflect symptoms of a specific type of depression or a vulnerability to develop depression.
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Two recent small studies showed that dimensional anxiety measures were not associated with hair cortisol levels in female MDD samples.
“Two recent small studies showed, however, that dimensional anxiety measures were not associated with hair cortisol levels in female MDD samples [69,70]”
From Patients with anxious depression: overview of prevalence, pathophysiology and impact on course and treatment outcome (2018) · cites this paper as [69]
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282 · see citing works
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267 · see citing works
(1970) · Cited by 24,983 · see citing works
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391 · see citing works
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139 · see citing works
Tzourio-Mazoyer, N., Landeau, B., Papathanassiou, D., Crivello, F., Etard, O., Delcroix, N., Mazoyer, B., & Joliot, M. (2002) · NeuroImage · doi:10.1006/nimg.2001.0978 · Cited by 16,319 · see citing works
Voxel-Based Morphometry—The Methods
Ashburner, J., & Friston, K. J. (2000) · NeuroImage · doi:10.1006/nimg.2000.0582 · Cited by 8,676 · see citing works
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., Rush, A. J., Walters, E. E., & Wang, P. S. (2003) · JAMA · doi:10.1001/jama.289.23.3095 · Cited by 7,988 · see citing works
A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains
Good, C. D., Johnsrude, I. S., Ashburner, J., Henson, R. N. A., Friston, K. J., & Frackowiak, R. S. J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0786 · Cited by 4,561 · see citing works
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391 · cited 1× · see citing works
“(PFC), and insula (Etkin and Wager, 2007; Stein et al., 2007; Sylvester et al., 2012).”
An overlap invariant entropy measure of 3D medical image alignment
Studholme, C., Hill, D., & Hawkes, D. J. (1999) · Pattern Recognition · doi:10.1016/s0031-3203(98)00091-0 · Cited by 2,167 · see citing works
Temperament, personality, and the mood and anxiety disorders.
Clark, L. A., Watson, D., & Mineka, S. (1994) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.103.1.103 · Cited by 1,685 · see citing works
Bogg, T., & Roberts, B. W. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.6.887 · Cited by 1,632 · cited 1× · see citing works
“Longitudinal studies with long term follow-up taking into account lifestyle aspects and personality trait like conscientiousness, which is related to good health-related behaviors (Bogg and Roberts, 2004), will be needed to verify this hypothesis.”
BackgroundThe economic cost of brain disorders in Europe
Olesen, J., Gustavsson, A., Svensson, M., Wittchen, H., & Jönsson, B. (2012) · European Journal of Neurology · doi:10.1111/j.1468-1331.2011.03590.x · Cited by 1,560 · see citing works
Multiple imputation in health‐are databases: An overview and some applications
Rubin, D. B., & Nathaniel Schenker, A. (1991) · Statistics in Medicine · doi:10.1002/sim.4780100410 · Cited by 1,553 · see citing works
Brown, T. A., Chorpita, B. F., & Barlow, D. H. (1998) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.107.2.179 · Cited by 1,400 · see citing works
Brown, T. A., Chorpita, B. F., & Barlow, D. H. (1998) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.107.2.179 · Cited by 1,400 · see citing works
Rethinking the mood and anxiety disorders: A quantitative hierarchical model for DSM-V.
Watson, D. (2005) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.114.4.522 · Cited by 1,332 · cited 2× · see citing works
“…to differ in their functional neural networks, but theoretical and empirical models indicate that these disorders share an important common factor of trait anxiety or negative affectivity (Clark et al., 1994; Brown et al., 1998; Hettema et al., 2005; 2006; Watson, 2005; Rosellini and Brown, 2011).”
BackgroundWinkler, A. M., Kochunov, P., Blangero, J., Almasy, L., Zilles, K., Fox, P. T., Duggirala, R., & Glahn, D. C. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.12.028 · Cited by 1,172 · see citing works
Fava, M., Rush, A. J., Alpert, J. E., Balasubramani, G. K., Wisniewski, S. R., Carmin, C. N., Biggs, M. M., Zisook, S., Leuchter, A., Howland, R., et al. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111868 · Cited by 927 · see citing works
Increased Amygdala and Insula Activation During Emotion Processing in Anxiety-Prone Subjects
Stein, M. B., Simmons, A. N., Feinstein, J. S., & Paulus, M. P. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.2.318 · Cited by 851 · see citing works
(2003) · Neuroepidemiology · doi:10.1159/000072920 · Cited by 672 · see citing works
Anxiety and Depression in Later Life: Co-Occurrence and Communality of Risk Factors
Beekman, A. T. F., de Beurs, E., van Balkom, A. J. L. M., Deeg, D. J. H., van Dyck, R., & van Tilburg, W. (2000) · American Journal of Psychiatry · doi:10.1176/ajp.157.1.89 · Cited by 669 · see citing works
A Population-Based Twin Study of the Relationship Between Neuroticism and Internalizing Disorders
Hettema, J. M., Neale, M. C., Myers, J., Prescott, C. A., & Kendler, K. S. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.5.857 · Cited by 633 · see citing works
Functional network dysfunction in anxiety and anxiety disorders
Sylvester, C. M., Corbetta, M., Raichle, M. E., Rodebaugh, T. L., Schlaggar, B. L., Sheline, Y. I., Zorumski, C. F., & Lenze, E. J. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.04.012 · Cited by 579 · see citing works
A comparison between voxel-based cortical thickness and voxel-based morphometry in normal aging
Hutton, C., Draganski, B., Ashburner, J., & Weiskopf, N. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.06.043 · Cited by 566 · see citing works
The Structure of Genetic and Environmental Risk Factors for Anxiety Disorders in Men and Women
Hettema, J. M., Prescott, C. A., Myers, J., Neale, M. C., & Kendler, K. S. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.2.182 · Cited by 541 · see citing works
Kessler, R. C., Birnbaum, H. G., Shahly, V., Bromet, E. J., Hwang, I. H., McLaughlin, K. A., Sampson, N. A., Andrade, L. H., de Girolamo, G., Demyttenaere, K., et al. (2009) · Depression and Anxiety · doi:10.1002/da.20634 · Cited by 477 · see citing works
Early diagnosis of Alzheimer's disease using cortical thickness: impact of cognitive reserve
Querbes, O., Aubry, F., Pariente, J., Lotterie, J.-A., Démonet, J., Duret, V., Puel, M., Berry, I., Fort, J., Celsis, P., et al. (2009) · Brain · doi:10.1093/brain/awp105 · Cited by 438 · see citing works
Self-citationFAVA, M., ALPERT, J. E., CARMIN, C. N., WISNIEWSKI, S. R., TRIVEDI, M. H., BIGGS, M. M., SHORES-WILSON, K., MORGAN, D., SCHWARTZ, T., BALASUBRAMANI, G. K., et al. (2004) · Psychological Medicine · doi:10.1017/s0033291704002612 · Cited by 406 · see citing works
Critical ages in the life course of the adult brain: nonlinear subcortical aging
Fjell, A. M., Westlye, L. T., Grydeland, H., Amlien, I. K., Espeseth, T., Reinvang, I., Raz, N., Holland, D., Dale, A. M., & Walhovd, K. B. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.04.006 · Cited by 393 · see citing works
Regional brain volume in depression and anxiety disorders
van Tol, M.-J., van der Wee, N. J. A., van den Heuvel, O. A., Nielen, M. M. A., Demenescu, L. R., Aleman, A., Renken, R., van Buchem, M. A., Zitman, F. G., & Veltman, D. J. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.121 · Cited by 370 · see citing works
Comorbid anxiety disorders in depressed elderly patients.
Lenze, E., Mulsant, B., Shear, M., Schulberg, H. C., Dew, M., Begley, A., Pollock, B., & Reynolds, C. F. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.722 · Cited by 327 · see citing works
Valkenburg, C. V., Akiskal, H. S., Puzantian, V. R., & Rosenthal, T. L. (1984) · Journal of Affective Disorders · doi:10.1016/0165-0327(84)90009-0 · Cited by 283 · see citing works
Temporal Profiles of the Course of Depression During Treatment
Dew, M. A. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830230050007 · Cited by 273 · see citing works
Health economics and cost implications of anxiety and other mental disorders in the United States
Rice, D. P., & Miller, L. S. (1998) · The British Journal of Psychiatry · doi:10.1192/s0007125000293458 · Cited by 261 · see citing works
Fuzzy spatial relationships for image processing and interpretation: a review
Bloch, I. (2004) · Image and Vision Computing · doi:10.1016/j.imavis.2004.06.013 · Cited by 234 · see citing works
Rosellini, A. J., & Brown, T. A. (2011) · Assessment · doi:10.1177/1073191110382848 · Cited by 217 · see citing works
Freeman, S. H., Kandel, R., Cruz, L., Rozkalne, A., Newell, K. L., Frosch, M. P., Hedley‐Whyte, E. T., Locascio, J. J., Lipsitz, L. A., & Hyman, B. T. (2008) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31818fc72f · Cited by 212 · see citing works
Remission in Depressed Geriatric Primary Care Patients: A Report From the PROSPECT Study
Alexopoulos, G. S., Katz, I. R., BRUCE, M. L., Heo, M., Have, T. T., Raue, P. J., Bogner, H. R., Schulberg, H. C., Mulsant, B. H., Reynolds, C. F., et al. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.4.718 · Cited by 205 · see citing works
Andreescu, C., Lenze, E. J., Dew, M. A., Begley, A. E., Mulsant, B. H., Dombrovski, A. Y., Pollock, B. G., STACK, J. A., Miller, M. D., & Reynolds, C. F. (2007) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.106.027169 · Cited by 196 · see citing works
Hardeveld, F., Spijker, J., De Graaf, R., Nolen, W. A., & Beekman, A. T. F. (2013) · Psychological Medicine · doi:10.1017/s0033291712002395 · Cited by 176 · see citing works
Amygdalar atrophy in panic disorder patients detected by volumetric magnetic resonance imaging
Massana, G., Serra-Grabulosa, J. M., Salgado‐Pineda, P., Gastó, C., Junqué, C., Massana, J., Mercader, J. M., Gómez‐Ansón, B., Tobeña, A., & Salamero, M. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00036-3 · Cited by 168 · see citing works
Smaller amygdala is associated with anxiety in patients with panic disorder
Hayano, F., Nakamura, M., Asami, T., Uehara, K., Yoshida, T., Roppongi, T., Otsuka, T., Inoue, T., & Hirayasu, Y. (2009) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2009.01960.x · Cited by 163 · see citing works
Localized gray matter volume abnormalities in generalized anxiety disorder
Schienle, A., Ebner, F., & Schäfer, A. (2010) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-010-0147-5 · Cited by 163 · see citing works
Regional gray matter abnormalities in panic disorder: A voxel-based morphometry study
Uchida, R. R., Del‐Ben, C. M., Busatto, G. F., Duran, F., Guimarães, F. S., Crippa, J. A. S., Araújo, D., dos Santos, A. C., & Graeff, F. G. (2008) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2007.04.015 · Cited by 156 · see citing works
Szeszko, P. R., Christian, C., MacMaster, F., Lencz, T., Mirza, Y., Taormina, S. P., Easter, P., Rose, M., Michalopoulou, G. A., & Rosenberg, D. R. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.08010033 · Cited by 143 · see citing works
When all hypotheses are right: A multifocal account of dyslexia
Pernet, C. R., Andersson, J., Paulesu, E., & Démonet, J. (2009) · Human Brain Mapping · doi:10.1002/hbm.20670 · Cited by 141 · see citing works
NEUROBIOLOGY OF ANXIOUS DEPRESSION: A REVIEW
Ionescu, D. F., Niciu, M. J., Mathews, D. C., Richards, E. M., & Zarate, C. A. (2013) · Depression and Anxiety · doi:10.1002/da.22095 · Cited by 140 · see citing works
Anxious Depression in Elderly Patients: Response to Antidepressant Treatment
Flint, A. J., & Rifat, S. L. (1997) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-199700520-00003 · Cited by 113 · see citing works
Parahippocampal Gray Matter Density in Panic Disorder: A Voxel-Based Morphometric Study
Massana, G., Serra-Grabulosa, J. M., Salgado‐Pineda, P., Gastó, C., Junqué, C., Massana, J., & Mercader, J. M. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.3.566 · Cited by 113 · see citing works
Increased brainstem volume in panic disorder: a voxel-based morphometric study
Protopopescu, X., Pan, H., Tüscher, O., Cloître, M., Goldstein, M., Engelien, A., Yang, Y., Gorman, J. M., LeDoux, J. E., Stern, E. R., et al. (2006) · Neuroreport · doi:10.1097/01.wnr.0000203354.80438.1 · Cited by 109 · see citing works
Anterior cingulate cortex volume reduction in patients with panic disorder
Asami, T., Hayano, F., Nakamura, M., Yamasue, H., Uehara, K., Otsuka, T., Roppongi, T., Nihashi, N., Inoue, T., & Hirayasu, Y. (2008) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2008.01800.x · Cited by 108 · see citing works
Sexually dimorphic gray matter volume reduction in patients with panic disorder
Asami, T., Yamasue, H., Hayano, F., Nakamura, M., Uehara, K., Otsuka, T., Roppongi, T., Nihashi, N., Inoue, T., & Hirayasu, Y. (2009) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2008.10.004 · Cited by 105 · see citing works
Putaminal gray matter volume decrease in panic disorder: an optimized voxel‐based morphometry study
Yoo, H. K., Kim, M. J., Kim, S. J., Sung, Y. H., Sim, M., Lee, Y. S., Song, S. Y., Kee, B. S., & Lyoo, I. K. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04394.x · Cited by 103 · see citing works
Kühn, S., Schubert, F., & Gallinat, J. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.06.003 · Cited by 102 · see citing works
Grey matter abnormalities in social anxiety disorder: a pilot study
Syal, S., Hattingh, C. J., Fouché, J., Spottiswoode, B. S., Carey, P. D., Löchner, C., & Stein, D. J. (2012) · Metabolic Brain Disease · doi:10.1007/s11011-012-9299-5 · Cited by 102 · see citing works
Neural Correlates of Anxiety in Healthy Volunteers: A Voxel-Based Morphometry Study
Spampinato, M. V., Wood, J. N., Simone, V. D., & Grafman, J. H. (2009) · Journal of Neuropsychiatry · doi:10.1176/jnp.2009.21.2.199 · Cited by 99 · see citing works
Structural evidence for involvement of a left amygdala-orbitofrontal network in subclinical anxiety
Blackmon, K., Barr, W. B., Carlson, C., Devinsky, O., DuBois, J., Pogash, D., Quinn, B. T., Kuzniecky, R., Halgren, E., & Thesen, T. (2011) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2011.05.007 · Cited by 90 · see citing works
The Default Mode Network In Late-Life Anxious Depression
Andreescu, C., Wu, M., Butters, M. A., Figurski, J. L., Reynolds, C. F., & Aizenstein, H. J. (2011) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e318227f4f9 · Cited by 79 · see citing works
Decreased left temporal lobe volume of panic patients measured by magnetic resonance imaging
Uchida, R. R., Del‐Ben, C. M., dos Santos, A. C., Araújo, D., Crippa, J. A. S., Guimarães, F. S., & Graeff, F. G. (2003) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2003000700014 · Cited by 70 · see citing works
Mohlman, J., Price, R. B., Eldreth, D. A., Chazin, D., Glover, D. M., & Kates, W. R. (2009) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2008.09.010 · Cited by 67 · see citing works
Sobanski, T., Wagner, G., Peikert, G., Gruhn, U., Schluttig, K., Sauer, H., & Schlösser, R. G. M. (2010) · Psychological Medicine · doi:10.1017/s0033291709991930 · Cited by 67 · see citing works
Cortical thickness alterations in social anxiety disorder
Frick, A., Howner, K., Fischer, H., Eskildsen, S. F., Kristiansson, M., & Furmark, T. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2012.12.060 · Cited by 65 · see citing works
Bundo, M., Kaneoke, Y., Inao, S., Yoshida, J., Nakamura, A., & Kakigi, R. (2000) · Human Brain Mapping · doi:10.1002/1097-0193(200009)11:1 · Cited by 62 · see citing works
Roppongi, T., Nakamura, M., Asami, T., Hayano, F., Otsuka, T., Uehara, K., Fujiwara, A., Saeki, T., Hayasaka, S., Yoshida, T., et al. (2010) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2010.02085.x · Cited by 62 · see citing works
Inkster, B., Rao, A. W., Ridler, K., Nichols, T. E., Saemann, P. G., Auer, D. P., Holsboer, F., Tozzi, F., Muglia, P., Merlo-Pich, E., et al. (2011) · Journal of Neuroimaging · doi:10.1111/j.1552-6569.2010.00515.x · Cited by 56 · see citing works
Bergua, V., Meillon, C., Potvin, O., Bouisson, J., Goff, M. L., Rouaud, O., Ritchie, K. A., Dartigues, J., & Amieva, H. (2012) · International Psychogeriatrics · doi:10.1017/s1041610212000300 · Cited by 53 · see citing works
Self-citationfMRI activation in late‐life anxious depression: a potential biomarker
Andreescu, C., Butters, M. A., Lenze, E. J., Venkatraman, V. K., Nable, M., Reynolds, C. F., & Aizenstein, H. J. (2009) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2327 · Cited by 44 · see citing works
A magnetic resonance imaging study of cortical thickness in animal phobia
Rauch, S. L., Wright, C. I., Martis, B., Busa, E., McMullin, K. G., Shin, L. M., Dale, A. M., & Fischl, B. R. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.12.022 · Cited by 40 · see citing works
ANXIETY AND 10-YEAR RISK OF INCIDENT AND RECURRENT DEPRESSIVE SYMPTOMATOLOGY IN OLDER ADULTS
Potvin, O., Bergua, V., Swendsen, J. D., Meillon, C., Tzourio, C., Ritchie, K. A., Dartigues, J., & Amieva, H. (2013) · Depression and Anxiety · doi:10.1002/da.22101 · Cited by 27 · see citing works
Self-citationAnxiety impairs depression remission in partial responders during extended treatment in late-life
Greenlee, A., Karp, J. F., Dew, M. A., Houck, P. R., Andreescu, C., & Reynolds, C. F. (2010) · Depression and Anxiety · doi:10.1002/da.20672 · Cited by 26 · see citing works
Comorbid anxiety and depression: bête noire or quick fix?
Andreescu, C., & Lenze, E. J. (2012) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.111.097022 · Cited by 15 · see citing works
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Besteher, B., Gaser, C., & Nenadić, I. (2020) · Neuropsychobiology · doi:10.1159/000501024 · Cited by 83 · see citing works
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- Authors
- Potvin, O., Catheline, G., Bernard, C., Meillon, C., Bergua, V., Allard, M., Dartigues, J.-F., Chauveau, N., Celsis, P., & Amieva, H.
- Affiliations
- Inserm (FR)
- Centre National de la Recherche Scientifique (FR)
- Université de Bordeaux (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Corresponding author
- Amieva, Hélène
- ORCID
- Venue
- International Psychogeriatrics
- Publisher
- Elsevier BV
- Published
- 2015-11
- Volume
- 27
- Issue
- 11
- Pages
- 1813-1824
- ISSN
- 1041-6102 (ISSN-L)
- OpenAlex
- W2276466620
- Cited by
- 25
- References
- 73
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 5 · 2018: 1 · 2017: 2 · 2015: 1
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Psychogeriatrics (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Oskar-Bordeaux (Universite de Bordeaux) (submittedVersion)
- Funders
- Agence Française de Sécurité Sanitaire des Produits de Santé
- Fondation de France
- Canadian Institutes of Health Research
- Mutuelle Générale de l'Education Nationale
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- trait anxiety, gray matter, cortical thickness, depression, older adults, amygdala, anterior cingulate cortex, insula, orbitofrontal cortex, temporal cortex, depressive symptoms, history of depression, depression vulnerability
- MeSH terms
- Aged, Anxiety, Brain, Depression, Female, Humans, Magnetic Resonance Imaging, Male, Psychiatric Status Rating Scales, Neuroimaging
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