The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Hydrogen Peroxide Displacing DNA from Nanoceria: Mechanism and Detection of Glucose in Serum
Open accessAbstract
Hydrogen peroxide (H2O2) is a key molecule in biology. As a byproduct of many enzymatic reactions, H2O2 is also a popular biosensor target. Recently, interfacing H2O2 with inorganic nanoparticles has produced a number of nanozymes showing peroxidase or catalase activities. CeO2 nanoparticle (nanoceria) is a classical nanozyme. Herein, a fluorescently labeled DNA is used as a probe, and H2O2 can readily displace adsorbed DNA from nanoceria, resulting in over 20-fold fluorescence enhancement. The displacement mechanism instead of oxidative DNA cleavage is confirmed by denaturing gel electrophoresis and surface group pKa measurement. This system can sensitively detect H2O2 down to 130 nM (4.4 parts-per-billion). When coupled with glucose oxidase, glucose is detected down to 8.9 μM in buffer. Detection in serum is also achieved with results comparable with that from a commercial glucose meter. With an understanding of the ligand role of H2O2, new applications in rational materials design, sensor development, and drug delivery can be further exploited.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
Nanostructures in Biodiagnostics
Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Wei, H., & Wang, E. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35486e · Cited by 3,779
Functional Nucleic Acid Sensors
Liu, J., Cao, Z., & Lu, Y. (2009) · Chemical Reviews · doi:10.1021/cr030183i · Cited by 2,187
Self-citationH 2 O 2 , a Necessary Evil for Cell Signaling
Rhee, S. G. (2006) · Science · doi:10.1126/science.1130481 · Cited by 2,160
Fluorescence probes used for detection of reactive oxygen species
Gomes, A., Fernandes, E., & Lima, J. L. F. C. (2005) · Journal of Biochemical and Biophysical Methods · doi:10.1016/j.jbbm.2005.10.003 · Cited by 1,844
Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?
Giorgio, M., Trinei, M., Migliaccio, E., & Pelicci, P. G. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2240 · Cited by 1,447
Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles
Korsvik, C., Patil, S., Seal, S., & Self, W. T. (2007) · Chemical Communications · doi:10.1039/b615134e · Cited by 1,278
Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes
Lin, Y., Ren, J., & Qu, X. (2014) · Accounts of Chemical Research · doi:10.1021/ar400250z · Cited by 1,252
Nanoceria exhibit redox state-dependent catalase mimetic activity
Pirmohamed, T., Dowding, J. M., Singh, S., Wasserman, B., Heckert, E., Karakoti, A. S., King, J. E. S., Seal, S., & Self, W. T. (2010) · Chemical Communications · doi:10.1039/b922024k · Cited by 1,214
Oxidase‐Like Activity of Polymer‐Coated Cerium Oxide Nanoparticles
Asati, A., Santra, S., Kaittanis, C., Nath, S., & Perez, J. M. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200805279 · Cited by 1,161
Pharmacological potential of cerium oxide nanoparticles
Celardo, I., Pedersen, J. Z., Traversa, E., & Ghibelli, L. (2011) · Nanoscale · doi:10.1039/c0nr00875c · Cited by 1,151
Xu, C., & Qu, X. (2014) · NPG Asia Materials · doi:10.1038/am.2013.88 · Cited by 1,133
Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species
Chen, X., Tian, X., Shin, I., & Yoon, J. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15037e · Cited by 980
Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides
Chen, J., Patil, S., Seal, S., & McGinnis, J. F. (2006) · Nature Nanotechnology · doi:10.1038/nnano.2006.91 · Cited by 880
Lippert, A. R., Van de Bittner, G. C., & Chang, C. J. (2011) · Accounts of Chemical Research · doi:10.1021/ar200126t · Cited by 798
Design of Gold Nanoparticle‐Based Colorimetric Biosensing Assays
Zhao, W., Brook, M. A., & Li, Y. (2008) · ChemBioChem · doi:10.1002/cbic.200800282 · Cited by 768
Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons
Das, M., Patil, S., Bhargava, N., Kang, J.-F., Riedel, L. M., Seal, S., & Hickman, J. J. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2006.11.036 · Cited by 760
Target-Responsive Structural Switching for Nucleic Acid-Based Sensors
Li, D., Song, S., & Fan, C. (2010) · Accounts of Chemical Research · doi:10.1021/ar900245u · Cited by 737
Nanozymes: Gold‐Nanoparticle‐Based Transphosphorylation Catalysts
Manea, F., Bodar-Houillon, F., Pasquato, L., & Scrimin, P. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200460649 · Cited by 706
Colorimetric Biosensing Using Smart Materials
Song, Y., Wei, W., & Qu, X. (2011) · Advanced Materials · doi:10.1002/adma.201101853 · Cited by 666
Self-Catalyzed, Self-Limiting Growth of Glucose Oxidase-Mimicking Gold Nanoparticles
Luo, W., Zhu, C., Su, S., Li, D., He, Y., Huang, Q., & Fan, C. (2010) · ACS Nano · doi:10.1021/nn102592h · Cited by 650
Methods for detection and measurement of hydrogen peroxide inside and outside of cells
Rhee, S. G., Chang, T.-S., Jeong, W., & Kang, D. (2010) · Molecules and Cells · doi:10.1007/s10059-010-0082-3 · Cited by 432
DNA-Mediated Homogeneous Binding Assays for Nucleic Acids and Proteins
Zhang, H., Li, F., Dever, B., Li, X.-F., & Le, X. C. (2013) · Chemical Reviews · doi:10.1021/cr300340p · Cited by 415
Lee, S. S., Song, W., Cho, M., Puppala, H. L., Nguyen, P., Zhu, H., Segatori, L., & Colvin, V. L. (2013) · ACS Nano · doi:10.1021/nn4026806 · Cited by 414
Adsorption of DNA onto gold nanoparticles and graphene oxide: surface science and applications
Liu, J. (2012) · Physical Chemistry Chemical Physics · doi:10.1039/c2cp41186e · Cited by 408
Self-citationSynthesis of Biocompatible Dextran‐Coated Nanoceria with pH‐Dependent Antioxidant Properties
Perez, J. M., Asati, A., Nath, S., & Kaittanis, C. (2008) · Small · doi:10.1002/smll.200700824 · Cited by 396
Inorganic Nanoparticles as Protein Mimics
Kotov, N. A. (2010) · Science · doi:10.1126/science.1190094 · Cited by 370
Catalytic Gold Nanoparticles for Nanoplasmonic Detection of DNA Hybridization
Zheng, X., Liu, Q., Jing, C., Li, Y., Li, D., Luo, W., Wen, Y., He, Y., Huang, Q., Long, Y., et al. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201105121 · Cited by 348
PEGylated Nanoceria as Radical Scavenger with Tunable Redox Chemistry
Karakoti, A. S., Singh, S., Kumar, A., Malinska, M., Kuchibhatla, S. V. N. T., Wozniak, K., Self, W. T., & Seal, S. (2009) · Journal of the American Chemical Society · doi:10.1021/ja9051087 · Cited by 343
Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition
Wang, H., Yang, R., Yang, L., & Tan, W. (2009) · ACS Nano · doi:10.1021/nn9006303 · Cited by 329
“Fitting” Makes “Sensing” Simple: Label-Free Detection Strategies Based on Nucleic Acid Aptamers
Du, Y., Li, B., & Wang, E. (2013) · Accounts of Chemical Research · doi:10.1021/ar300011g · Cited by 234
Attaching DNA to Nanoceria: Regulating Oxidase Activity and Fluorescence Quenching
Pautler, R., Kelly, E. Y., Huang, P.-J. J., Cao, J., Liu, B., & Liu, J. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am4018863 · Cited by 218
Self-citationNucleic Acid/Quantum Dots (QDs) Hybrid Systems for Optical and Photoelectrochemical Sensing
Freeman, R., Girsh, J., & Willner, I. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am303189h · Cited by 214
Acquired Superoxide‐Scavenging Ability of Ceria Nanoparticles
Li, Y., He, X., Yin, J., Ma, Y., Zhang, P., Li, J., Ding, Y., Zhang, J., Zhao, Y., Chai, Z., et al. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201410398 · Cited by 211
Portable ceria nanoparticle-based assay for rapid detection of foodantioxidants (NanoCerac)
Sharpe, E., Frasco, T., Andreescu, D., & Andreescu, S. (2013) · The Analyst · doi:10.1039/c2an36205h · Cited by 164
Xu, C., Liu, Z., Wu, L. J., Ren, J., & Qu, X. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201301649 · Cited by 130
Lin, Y., Xu, C., Ren, J., & Qu, X. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201207587 · Cited by 116
Characterization of glucose oxidation by gold nanoparticles using nanoceria
Lang, N. J., Liu, B., & Liu, J. (2014) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2014.04.025 · Cited by 113
Self-citationWang, L., Zheng, J., Li, Y., Yang, S., Liu, C., Xiao, Y., Li, J., Cao, Z. Y., & Yang, R. (2014) · Analytical Chemistry · doi:10.1021/ac503653c · Cited by 109
Sardesai, N. P., Andreescu, D., & Andreescu, S. (2013) · Journal of the American Chemical Society · doi:10.1021/ja408087s · Cited by 107
McCormack, R. N., Mendez, P., Barkam, S., Neal, C. J., Das, S., & Seal, S. (2014) · The Journal of Physical Chemistry C · doi:10.1021/jp500791j · Cited by 85
Redox reactivity of cerium oxide nanoparticles against dopamine
Hayat, A., Andreescu, D., Bülbül, G., & Andreescu, S. (2013) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2013.12.007 · Cited by 82
The Vital Role of Buffer Anions in the Antioxidant Activity of CeO2 Nanoparticles
Xue, Y., Zhai, Y., Zhou, K., Wang, L., Tan, H., Luan, Q., & Yao, X. (2012) · Chemistry - A European Journal · doi:10.1002/chem.201200983 · Cited by 81
Menchón, C., Martín, R., Apostolova, N., Víctor, V. M., Álvaro, M., Herance, J. R., & García, H. (2012) · Small · doi:10.1002/smll.201102255 · Cited by 47
Cited by
Surface modification of nanozymes
Liu, B., & Liu, J. (2017) · Nano Research · doi:10.1007/s12274-017-1426-5 · Cited by 543
Self-citationMulticopper Laccase Mimicking Nanozymes with Nucleotides as Ligands
Liang, H., Lin, F., Zhang, Z., Liu, B., Jiang, S., Yuan, Q., & Liu, J. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b15124 · Cited by 537
Self-citationEnzyme Mimicry for Combating Bacteria and Biofilms
Chen, Z., Wang, Z., Ren, J., & Qu, X. (2018) · Accounts of Chemical Research · doi:10.1021/acs.accounts.8b00011 · Cited by 499
Site-selective photoinduced cleavage and profiling of DNA by chiral semiconductor nanoparticles
Sun, M., Xu, L., Qu, A., Zhao, P., Hao, T., Ma, W., Hao, C., Wen, X., Colombari, F. M., de Moura, A. F., et al. (2018) · Nature Chemistry · doi:10.1038/s41557-018-0083-y · Cited by 298
Cheng, H., Liu, Y., Hu, Y., Ding, Y., Lin, S., Cao, W., Wang, Q., Wu, J., Muhammad, F., Zhao, X., et al. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b02895 · Cited by 267
Metadata
- Authors
- Liu, B., Sun, Z., Huang, P.-J. J., & Liu, J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-01-20
- Volume
- 137
- Issue
- 3
- Pages
- 1290-1295
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2049188949
- Cited by
- 419
- References
- 45
- FWCI
- 18.65
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
