The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Porous Hollow Fe3O4 Nanoparticles for Targeted Delivery and Controlled Release of Cisplatin
Open accessAbstract
We report a new approach to cisplatin storage and release using porous hollow nanoparticles (PHNPs) of Fe(3)O(4). We prepared the PHNPs by controlled oxidation of Fe NPs at 250 degrees C followed by acid etching. The opening pores ( approximately 2-4 nm) facilitated the cisplatin diffusion into the cavity of the hollow structure. The porous shell was stable in neutral or basic physiological conditions, and cisplatin escape from the cavity through the same pores was a diffusion-controlled slow process with t(1/2) = 16 h. However, in low pH (<6) conditions, the pores were subject to acidic etching, resulting in wider pore gaps and faster release of cisplatin with t(1/2) < 4 h. Once coupled with Herceptin to the surface, the cisplatin-loaded hollow NPs could target to breast cancer SK-BR-3 cells with IC(50) reaching 2.9 muM, much lower than 6.8 muM needed for free cisplatin. Our model experiments indicate that the low pH-responsive PHNPs of Fe(3)O(4) can be exploited as a cisplatin delivery vehicle for target-specific therapeutic applications.
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., Li, J. J., Sundaresan, G., Wu, A. M., Gambhir, S. S., & Weiss, S. (2005) · Science · doi:10.1126/science.1104274 · Cited by 7,790
Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Vander Elst, L., & Muller, R. N. (2008) · Chemical Reviews · doi:10.1021/cr068445e · Cited by 6,852
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
Gupta, A. K., & Gupta, M. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.10.012 · Cited by 6,771
Quantum dot bioconjugates for imaging, labelling and sensing
Medintz, I. L., Uyeda, H. T., Goldman, E. R., & Mattoussi, H. (2005) · Nature Materials · doi:10.1038/nmat1390 · Cited by 6,229
Ritger, P. L., & Peppas, N. A. (1987) · Journal of Controlled Release · doi:10.1016/0168-3659(87)90034-4 · Cited by 3,830
Cellular processing of platinum anticancer drugs
Wang, D., & Lippard, S. J. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1691 · Cited by 3,801
Cisplatin: mode of cytotoxic action and molecular basis of resistance
Siddik, Z. H. (2003) · Oncogene · doi:10.1038/sj.onc.1206933 · Cited by 3,335
Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode
ROSENBERG, B., VAN CAMP, L., & KRIGAS, T. (1965) · Nature · doi:10.1038/205698a0 · Cited by 3,049
The use of nanocrystals in biological detection
Alivisatos, P. (2004) · Nature Biotechnology · doi:10.1038/nbt927 · Cited by 3,008
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
Jamieson, E. R., & Lippard, S. J. (1999) · Chemical Reviews · doi:10.1021/cr980421n · Cited by 2,949
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Li, D., Wang, C., Tripkovic, D., Sun, S., Markovic, N. M., & Stamenkovic, V. R. (2012) · ACS Catalysis · doi:10.1021/cs300219j · Cited by 508
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Xu, C., & Sun, S. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.008 · Cited by 349
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Lee, N., Choi, Y., Lee, Y., Park, M., Moon, W. K., Choi, S. H., & Hyeon, T. (2012) · Nano Letters · doi:10.1021/nl3010308 · Cited by 293
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Deng, Z., Zhen, Z., Hu, X., Wu, S., Xu, Z., & Chu, P. K. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.03.050 · Cited by 264
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Metadata
- Authors
- Cheng, K., Peng, S., Xu, C., & Sun, S.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-07-02
- Volume
- 131
- Issue
- 30
- Pages
- 10637-10644
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2024942244
- Cited by
- 438
- References
- 42
- FWCI
- 16.27
- Type
- journal article
- Language
- en
- Open access
- green
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