The DOI matches its Crossref record; 172 of the 175 references it cites were found in a registry or an index.
The Emotional Brain, Fear, and the Amygdala
Open accessAbstract
1. Considerable progress has been made over the past 20 years in relating specific circuits of the brain to emotional functions. Much of this work has involved studies of Pavlovian or classical fear conditioning, a behavioral procedure that is used to couple meaningless environmental stimuli to emotional (defense) response networks. 2. The major conclusion from studies of fear conditioning is that the amygdala plays critical role in linking external stimuli to defense responses. 3. Before describing research on the role of the amygdala in fear conditioning, though, it will be helpful to briefly examine the historical events that preceded modern research on conditioned fear.
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In the citing paper
“Briefly, the association between a stimulus predicting shock and the shock forms in basolateral regions of the amygdala.”
From Learned helplessness at fifty: Insights from neuroscience. (2016) · cites this paper as LeDoux, 2003
In the citing paper
“From there the information passes to the central nucleus of the amygdala, which in turns projects to the regions that control the behaviors and physiological responses that are the symptoms of fear (Davis, Rainnie, & Cassell, 1994; LeDoux, 2003; Maren & Quirk, 2004).”
From Learned helplessness at fifty: Insights from neuroscience. (2016) · cites this paper as LeDoux, 2003
In the citing paper
“The anatomical projections from the amygdala and mPFC to the hypothalamus, PAG, locus ceruleus, raphe, and autonomic-related brainstem nuclei play major roles in organizing the endocrine, autonomic, and behavioral responses to stressors and emotional stimuli (Figure 10) (Davis and Shi, 1999;LeDoux, 2003;O ¨ngu ¨r et al, 2003).”
From Neurocircuitry of Mood Disorders (2010) · cites this paper as LeDoux, 2003
In the citing paper
“Parallel and convergent efferent projections from the amygdala and the medial prefrontal network to the hypothalamus, periaqueductal gray (PAG), nucleus basalis, locus ceruleus, dorsal raphe, and medullary vagal nuclei organize neuroendocrine, autonomic, neurotransmitter and behavioral responses to stressors and emotional stimuli”
From Neurocircuitry of Mood Disorders (2010) · cites this paper as LeDoux, 2003
In the citing paper
“Amygdala stimulation of the locus ceruleus, lateral hypothalamus and PAG increases sympathetic autonomic arousal in rodents (Fig. 5) (LeDoux 2003; Gold and Chrousos 2002).”
From Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression (2008) · cites this paper as LeDoux 2003
In the citing paper
“The BLA sends anatomical projections to the central nucleus of the amygdala (ACe) and the BNST, and projections from these structures to the hypothalamus, PAG, nucleus basalis, locus ceruleus, raphe and other diencencephalic and brainstem nuclei play major roles in organizing the neuroendocrine, neurotransmitter, autonomic, and behavioral responses to stressors and emotional stimuli (Davis and Shi”
From Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression (2008) · cites this paper as LeDoux 2003
In the citing paper
“positive memories are rarely induced in mice, unlike fear conditioning, which is more commonly used for its robustness and long-lasting effects [45–47].”
From Positive early-life olfactory memory is rooted in the olfactory bulb and triggers large-scale changes beyond the olfactory system (2026) · cites this paper as [46]
In the citing paper
“The expression and inhibition of learned fear is largely regulated by the amygdala, hippocampus, and PFC in adult rodents and humans (Knapska et al., 2012;LeDoux, 2003;Maren and Quirk, 2004;Tovote et al., 2015)”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as LeDoux, 2003
In the citing paper
“required for the acquisition and expression of learned fear”
From Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience (2014) · cites this paper as LeDoux, 2003
In the citing paper
“Fear is a defensive mechanism that activates behavioral and neurobiological responses to danger that promote survival, including freezing and activation of sympathetic nervous system and HPA axis”
From Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience (2014) · cites this paper as LeDoux, 2003
In the citing paper
“An extensive literature in rodents has characterized the neural circuitry that underlies fear learning using Pavlovian fear conditioning tasks”
From Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience (2014) · cites this paper as LeDoux, 2003
In the citing paper
“The CMA is critical in the generation of behavioral responses through projections to the brainstem, striatum, and regions of the cortex (LeDoux, 2003).”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as LeDoux, 2003
In the citing paper
“The amygdala can be subdivided into basolateral (BLA), centromedial (CMA) and superficial (SFA) nuclei, each with distinct functional connections to the cortex supporting different brain functions.”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as LeDoux, 2003
In the citing paper
“The BLA facilitates associative learning processes, like fear conditioning, through afferent projections from the frontal cortex and other subcortical regions (LeDoux, 2003, Phelps and LeDoux, 2005).”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as LeDoux, 2003
In the citing paper
“Converging evidence from this field suggests the amygdalaa key brain region for emotion regulation (LeDoux, 2003), processing (Seeley et al., 2007), detection (Ousdal et al., 2008), and vigilance for social cues across sensory modalities (Whalen, 2007) is an important target of OT administration.”
In the citing paper
“decreasing amygdala cholinergic activity through α4β2* nAChR blockade could decrease stress reactivity and depression-like symptoms (LeDoux, 2003; Mineur et al., 2007)”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as LeDoux, 2003
In the citing paper
“The quality of parent-child relationships affects both sexual behavior and neural development and activation, specifically in the amygdala”
From Becoming a sexual being: The “elephant in the room” of adolescent brain development (2017) · cites this paper as LeDoux, 2003
In the citing paper
“which has been associated with reward processing (Ernst et al., 2005), emotional processing (Whalen et al., 2013), and fear response (LeDoux, 2003)”
From Becoming a sexual being: The “elephant in the room” of adolescent brain development (2017) · cites this paper as LeDoux, 2003
Citations
Cites
(1999) · Cited by 12,812
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Plum, F. (1960) · Archives of Neurology · doi:10.1001/archneur.1960.03840090124020 · Cited by 10,388
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Self-citationDESCARTES' ERROR: Emotion, Reason, and the Human Brain
Marg, E. (1995) · Optometry and Vision Science · doi:10.1002/j.1538-9235.1995.tb03988.x · Cited by 8,178
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120
Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,424
(1995) · Medical Entomology and Zoology · Cited by 7,217
Working with Emotional Intelligence
Goleman, D. (1999) · ETC: A Review of General Semantics · doi:10.66774/etc_5601_103 · Cited by 6,254
(1962) · Medical Entomology and Zoology · Cited by 4,856
Cited by
Sorted by citations
Items 501–600 of 1,004
Naumann, R. T., & Kanwal, J. S. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00580.2010 · Cited by 50
Cha, J., DeDora, D. J., Nedic, S., Ide, J. S., Greenberg, T., Hajcak, G., & Mujica-Parodi, L. R. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1092-15.2016 · Cited by 50
Fardell, L. L., Pavey, C. R., & Dickman, C. R. (2020) · PeerJ · doi:10.7717/peerj.9104 · Cited by 50
Functional Mapping of Dynamic Happy and Fearful Facial Expression Processing in Adolescents
Rahko, J. S., Paakki, J., Starck, T., Nikkinen, J., Remes, J. J., Hurtig, T. M., Kuusikko‐Gauffin, S., Mattila, M., Jussila, K. K., Jansson-Verkasalo, E. M., et al. (2010) · Brain Imaging and Behavior · doi:10.1007/s11682-010-9096-x · Cited by 50
Music tempo modulates emotional states as revealed through EEG insights
Yang, Z., Su, Q., Xie, J., Su, H., Huang, T., Han, C., Zhang, S., Zhang, K., & Xu, G. (2025) · Scientific Reports · doi:10.1038/s41598-025-92679-1 · Cited by 49
Infants' attention is biased by emotional expressions and eye gaze direction
Hoehl, S., Palumbo, L., Heinisch, C., & Striano, T. (2008) · Neuroreport · doi:10.1097/wnr.0b013e3282f97897 · Cited by 49
Vai, B., Papa, G. S., Poletti, S., Radaelli, D., Donnici, E., Bollettini, I., Falini, A., Cavallaro, R., Smeraldi, E., & Benedetti, F. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2015.01.002 · Cited by 49
Petro, N. M., Gruss, L. F., Yin, S., Huang, H., Miskovic, V., Ding, M., & Keil, A. (2017) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01114 · Cited by 49
Velazco, D. J. M., Martínez, M. F. C., Rivas, G., & Carmona, C. S. V. (2021) · The Education and science journal · doi:10.17853/1994-5639-2021-2-94-113 · Cited by 49
Suarez, G. L., Burt, S. A., Gard, A. M., Burton, J. Z., Clark, D. A., Klump, K. L., & Hyde, L. W. (2022) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2022.101061 · Cited by 49
Fear and pulmonary stress behaviors to an asphyxial threat across cognitive states
Campbell, M. (2007) · Research in Nursing & Health · doi:10.1002/nur.20212 · Cited by 49
Lanteaume, L., Bartoloméi, F., & Bastien‐Toniazzo, M. (2009) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2009.03.034 · Cited by 49
Perlis, R. H. (2008) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.3 · Cited by 49
Cortico-amygdala circuits: Role in the conditioned stress response
Berretta, S. (2005) · Stress · doi:10.1080/10253890500489395 · Cited by 49
Delaney, A., Sedlak, P. L., Autuori, E., Power, J., & Sah, P. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00176.2012 · Cited by 48
Silberman, Y., Ariwodola, O. J., Chappell, A. M., Yorgason, J. T., & Weiner, J. L. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.59 · Cited by 48
Mukherjee, P., Whalley, H. C., McKirdy, J. W., McIntosh, A. M., Johnstone, E. C., Lawrie, S. M., & Hall, J. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.09.033 · Cited by 48
Christensen, J. F., Pollick, F. E., Lambrechts, A., & Gomila, A. (2016) · Acta Psychologica · doi:10.1016/j.actpsy.2016.03.008 · Cited by 48
Compassion-focused therapy with children and adolescents
Carona, C., Rijo, D., Salvador, C., Castilho, P., & Gilbert, P. (2017) · BJPsych Advances · doi:10.1192/apt.bp.115.015420 · Cited by 48
Cohen‐Gilbert, J. E., Nickerson, L. D. H., Sneider, J. T., Oot, E. N., Seraikas, A. M., Rohan, M. L., & Silveri, M. M. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01650 · Cited by 48
Assessments of Cognitive Deficits in Mutant Mice
Levin, E. D., & Buccafusco, J. J. (2006) · CRC Press eBooks · doi:10.1201/9781420004335-17 · Cited by 48
Johansson, A., & Dell’Acqua, P. (2012) · IEEE Conference on Computational Intelligence and Games (CIG) · doi:10.1109/cig.2012.6374177 · Cited by 48
Ousdal, O. T., Andreassen, O. A., Server, A., & Jensen, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096146 · Cited by 48
The antidepressant effect of light therapy from retinal projections.
Li, X., & Li, X. (2018) · Neuroscience Bulletin · doi:10.1007/s12264-018-0210-1 · Cited by 47
Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4
Gomez, A. M., Froemke, R. C., & Burden, S. J. (2014) · eLife · doi:10.7554/elife.04287 · Cited by 47
Ritov, G., Ardi, Z., & Richter‐Levin, G. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00018 · Cited by 47
Li, Y., Qin, W., Jiang, T., Zhang, Y., & Yu, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035925 · Cited by 47
Neuroanatomical Correlates of Recognizing Face Expressions in Mild Stages of Alzheimer’s Disease
Sapey‐Triomphe, L., Heckemann, R. A., Boublay, N., Dorey, J., Hénaff, M., Rouch, I., Padovan, C., Hammers, A., Krolak‐Salmon, P., & Initiative, A. D. N. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143586 · Cited by 47
Slow to warm up: the role of habituation in social fear
Avery, S. N., & Blackford, J. U. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw095 · Cited by 47
Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence
Uhrig, S., Vandael, D. H. F., Marcantoni, A., Dedic, N., Bilbao, A., Vogt, M. A., Hirth, N., Broccoli, L., Bernardi, R. E., Schönig, K., et al. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.266 · Cited by 47
Blons, E., Arsac, L. M., Gilfriche, P., McLeod, H., Lespinet‐Najib, V., Grivel, É., & Deschodt‐Arsac, V. (2019) · Scientific Reports · doi:10.1038/s41598-019-54547-7 · Cited by 47
Youngs, R. M., Chu, M. S., Meloni, E. G., Naydenov, A. V., Carlezon, W. A., & Konradi, C. L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0580-06.2006 · Cited by 47
Prediction of Selective Serotonin Reuptake Inhibitor Response Using Diffusion-Weighted MRI
DeLorenzo, C., Delaparte, L., Thapa-Chhetry, B., Miller, J. M., Mann, J. J., & Parsey, R. V. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00005 · Cited by 47
Waldie (2013) · doi:10.3389/fnhum.2014.00757 · Cited by 46
Singleton, S. P., Wang, J. B., Mithoefer, M. C., Hanlon, C. A., George, M. S., Mithoefer, A., Mithoefer, O. J., Coker, A. R., Yazar‐Klosinski, B., Emerson, A., et al. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.947622 · Cited by 46
Cannady, R., Grondin, J. J. M., Fisher, K. R., Hodge, C. W., & Besheer, J. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.121 · Cited by 46
McCrory, E. J. P., Ogle, J. R., Gerin, M. I., & Viding, E. M. (2019) · Child Maltreatment · doi:10.1177/1077559519830524 · Cited by 46
de Borst, A. W., Sanchez-Vives, M. V., Slater, M., & de Gelder, B. (2020) · eNeuro · doi:10.1523/eneuro.0263-19.2019 · Cited by 46
Wang, M., Zeng, N., Zheng, H., Du, X., Potenza, M. N., & Dong, G.-H. (2020) · Psychological Medicine · doi:10.1017/s0033291720002366 · Cited by 46
Brooks, S. J., O’Daly, O., Uher, R., Schiöth, H. B., Treasure, J. L., & Campbell, I. C. (2012) · Consciousness and Cognition · doi:10.1016/j.concog.2012.02.006 · Cited by 46
Yaseen, Z. S., Chartrand, H., Mojtabai, R., Bolton, J. M., & GALYNKER, I. I. (2012) · Depression and Anxiety · doi:10.1002/da.22039 · Cited by 46
Clinard, C. T., Bader, L. R., Sullivan, M. A., & Cooper, M. A. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.11.016 · Cited by 45
Deficits in emotional learning and memory in an animal model of schizophrenia
Bolton, M. M., Heaney, C. F., Sabbagh, J. J., Murtishaw, A. S., Magcalas, C. M., & Kinney, J. W. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.04.049 · Cited by 45
Risk as affect: The affect heuristic in cybersecurity
van Schaik, P., Renaud, K., Wilson, C., Jansen, J., & Onibokun, J. (2019) · Computers & Security · doi:10.1016/j.cose.2019.101651 · Cited by 45
Personality Traits and Emotional Word Recognition: An ERP Study
Ku, L.-C., Chan, S.-H., & Lai, V. T. (2020) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-020-00774-9 · Cited by 45
Temporal dynamics of Arc gene induction in hippocampus: Relationship to context memory formation
Pevzner, A., Miyashita, T., Schiffman, A. J., & Guzowski, J. F. (2012) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2012.02.004 · Cited by 45
Rat Neonatal Immune Challenge Alters Adult Responses to Cerebral Ischaemia
Spencer, S. J., Auer, R. N., & Pittman, Q. J. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600206 · Cited by 45
Effects of medial amygdala inactivation on a panic-related behavior
Herdade, K. C. P., Strauss, C. V. D. A., Júnior, H. Z., & Viana, M. D. B. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.05.021 · Cited by 45
Yun, R. J., Krystal, J. H., & Mathalon, D. H. (2010) · Brain Imaging and Behavior · doi:10.1007/s11682-010-9089-9 · Cited by 45
Marchewka, A., Wypych, M., Michałowski, J. M., Sińczuk, M., Draps, M., Jednoróg, K., & Nowicka, A. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00378 · Cited by 45
Transdiagnostic brain responses to disorder-related threat across four psychiatric disorders
Feldker, K., Heitmann, C. Y., Neumeister, P., Tupak, S. V., Schrammen, E., Moeck, R., Zwitserlood, P., Bruchmann, M., & Straube, T. (2016) · Psychological Medicine · doi:10.1017/s0033291716002634 · Cited by 45
Strategic regulation of cognitive control by emotional salience: a neural network model
Wyble, B., Sharma, D., & Bowman, H. (2008) · Cognition & Emotion · doi:10.1080/02699930701597627 · Cited by 44
On the role of subsecond dopamine release in conditioned avoidance
Oleson, E. B., & Cheer, J. F. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00096 · Cited by 44
de Oliveira, A. R., Reimer, A. E., Reis, F. M., & Brandão, M. L. (2012) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.05.007 · Cited by 44
Martin, W., Murray, P. S., Bates, P. R., & Lee, P. S. Y. (2016) · Aviation Psychology and Applied Human Factors · doi:10.1027/2192-0923/a000092 · Cited by 44
Benbasat, I., Dimoka, A., Pavlou, P. A., & Qiu, L. (2019) · International Journal of Human-Computer Studies · doi:10.1016/j.ijhcs.2019.09.001 · Cited by 44
Dimoka, A. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.05.007 · Cited by 44
Memories of 100 years of human fear conditioning research and expectations for its future
Vervliet, B., & Boddez, Y. (2020) · Behaviour Research and Therapy · doi:10.1016/j.brat.2020.103732 · Cited by 44
Imaging the Human Parental Brain
Swain, J. E., & Lorberbaum, J. P. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374285-8.00006-8 · Cited by 43
Kelschenbach, J., He, H., Kim, B., Borjabad, A., Gu, C., Chao, W., Do, M., Sharer, L. R., Zhang, H., Arancio, O., et al. (2019) · mBio · doi:10.1128/mbio.00591-19 · Cited by 43
Franco, C. L., & Fugate, J. M. B. (2020) · Journal of Nonverbal Behavior · doi:10.1007/s10919-019-00330-1 · Cited by 43
Prepulse inhibition of the acoustic startle reflex and P50 gating in aging and alzheimer’s disease
Jafari, Z., Kolb, B. E., & Mohajerani, M. H. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101028 · Cited by 43
Game Strategies for Physical Robot Soccer Players: A Survey
Antonioni, E., Suriani, V., Riccio, F., & Nardi, D. (2021) · IEEE Transactions on Games · doi:10.1109/tg.2021.3075065 · Cited by 43
Perirhinal cortex supports acquired fear of auditory objects
Bang, S. J., & Brown, T. H. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.01.002 · Cited by 43
Lewis, M. C., & Gould, T. J. (2007) · Hippocampus · doi:10.1002/hipo.20284 · Cited by 42
Conditioned fear modulates visual selection.
Mulckhuyse, M., Crombez, G., & Van der Stigchel, S. (2013) · Emotion · doi:10.1037/a0031076 · Cited by 42
Mieling, M., Meier, H., & Bunzeck, N. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105393 · Cited by 42
Embedding emotion awareness into e-learning environments
Feidakis, M., Daradoumis, Τ., Caballé, S., & Conesa, J. (2014) · International Journal of Emerging Technologies in Learning (iJET) · doi:10.3991/ijet.v9i7.3727 · Cited by 42
Yu, X., Liu, L., Chen, W., Cao, Q., Zepf, F. D., Ji, G., Wu, Z.-M., An, L., Wang, P., Qian, Q., et al. (2016) · Journal of Attention Disorders · doi:10.1177/1087054716661419 · Cited by 42
Yu, H., Chen, L., Li, H., Xin, H., Zhang, J., Wei, Z., & Peng, D. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s191441 · Cited by 42
Dong, M., Xia, L., Lü, M., Li, C., Ke Cheng, X. U., & Zhang, L. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134314 · Cited by 42
Parent–Child Relationships in the Puberty Years: Insights From Developmental Neuroscience
Suleiman, A. B., & Dahl, R. E. (2019) · Family Relations · doi:10.1111/fare.12360 · Cited by 42
DeCross, S. N., Sambrook, K., Sheridan, M. A., Tottenham, N., & McLaughlin, K. A. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.09.013 · Cited by 42
Startle responses in Duchenne muscular dystrophy: a novel biomarker of brain dystrophin deficiency
Maresh, K. E., Papageorgiou, A., Ridout, D. A., Harrison, N. A., Mandy, W., Skuse, D., & Muntoni, F. (2022) · Brain · doi:10.1093/brain/awac048 · Cited by 42
Baldo, B. A., Alsene, K. M., Negrón, A., & Kelley, A. E. (2005) · Behavioral Neuroscience · doi:10.1037/0735-7044.119.5.1195 · Cited by 42
Willgoss, T. G., Yohannes, A. M., Goldbart, J., & Fatoye, F. (2012) · Heart & Lung · doi:10.1016/j.hrtlng.2012.07.003 · Cited by 42
Role of the Bed Nucleus of the Stria Terminalis (BST) in the Expression of Conditioned Fear
MELONI, E. G., JACKSON, A., GERETY, L. P., COHEN, B. M., & CARLEZON, W. A. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.059 · Cited by 41
Klug, M., Enneking, V., Borgers, T., Jacobs, C. M., Dohm, K., Kraus, A., Grotegerd, D., Opel, N., Repple, J., Suslow, T., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02429-4 · Cited by 41
Shukla, S., Torossian, A., Duann, J., & Leung, A. (2011) · Molecular Pain · doi:10.1186/1744-8069-7-45 · Cited by 41
Cortical morphometric predictors of autonomic dysfunction in generalized anxiety disorder
Carnevali, L., Mancini, M., Koenig, J., Makovac, E., Watson, D. R., Meeten, F., Critchley, H., & Ottaviani, C. (2019) · Autonomic Neuroscience · doi:10.1016/j.autneu.2019.01.001 · Cited by 41
Hoffman, A. N., & Taylor, A. N. (2019) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000461 · Cited by 41
Tan, Y. H. V., Wu, X., Chen, J., Kong, L., & Qian, Z. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.01700 · Cited by 41
Amygdala functional connectivity is reduced after the cold pressor task
Clewett, D., Schoeke, A., & Mather, M. (2013) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-013-0162-x · Cited by 41
Oliva, J. M., Ortiz, S., Pérez-Rial, S., & Manzanares, J. (2007) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2007.09.001 · Cited by 41
Mahabir, M., Tucholka, A., Shin, L. M., Etienne, P. E., & Brunet, A. (2015) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2015.10.004 · Cited by 41
Markram, H., López‐Fernández, M. A., Abrous, D. N., & Sandi, C. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2006.11.007 · Cited by 41
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Metadata
- Authors
- LeDoux, J.
- Affiliations
- New York University (US)
- Corresponding author
- LeDoux, Joseph
- ORCID
- LeDoux, Joseph
- Venue
- Cellular and Molecular Neurobiology
- Published
- 2003-10
- Volume
- 23
- Issue
- 4-5
- Pages
- 727-738
- ISSN
- 0272-4340 (ISSN-L)
- 1573-6830
- PMC
- PMC11530156
- OpenAlex
- W1513763202
- Cited by
- 1,818
- References
- 175
- Citations by year
- 2026: 60 · 2025: 85 · 2024: 80 · 2023: 73 · 2022: 73 · 2021: 119 · 2020: 88 · 2019: 125 · 2018: 83 · 2017: 87 · 2016: 114 · 2015: 95 · 2014: 77 · 2013: 85 · 2012: 96
- FWCI
- 16.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Cellular and Molecular Neurobiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- amygdala, fear conditioning, classical conditioning, emotional brain, defense response, emotional circuits
- MeSH terms
- Amygdala, Animals, Conditioning, Psychological, Emotions, Fear, Humans, Limbic System, Models, Neurological, Neural Pathways, Sensation, Models, Animal
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