Posttraumatic stress disorder and anxious and fearful reactivity to bodily arousal: A test of the mediating role of nicotine withdrawal severity among daily smokers in 12-hr nicotine deprivation.
Abstract
Posttraumatic stress disorder (PTSD) is associated with high rates of smoking and fear of bodily perturbation. The current study examined the role of nicotine withdrawal in the association between PTSD and responding to bodily arousal among 52 participants (27 women; M-sub(age) = 30.50 years). Compared to participants without current axis I psychopathology, persons with current PTSD responded to a 3-min voluntary hyperventilation procedure with greater increases in anxiety and more intense cognitive and physical panic symptoms, despite no group differences in physiological arousal. Nicotine withdrawal demonstrated significant mediational effects in the relations between diagnostic group and panic symptoms elicited by the hyperventilation procedure. Findings suggest nicotine withdrawal is an important factor to consider in terms of better understanding the nature of fear responding to bodily sensations among persons with PTSD.
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Nicotine affects dopamine release, providing temporary pleasure and reinforcing the perception that smoking alleviates mental health symptoms, despite actually worsening these symptoms in the long-term.
“Nicotine affects dopamine release, providing temporary pleasure and reinforcing the perception that smoking alleviates mental health symptoms, despite actually worsening these symptoms in the long-term [12, 13, 14, 15].”
From Can an Acceptance and Commitment Therapy-Based Smartphone App Help Individuals with Mental Health Disorders Quit Smoking? (2024) · cites this paper as [13]
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- Authors
- Feldner, M. T., Vujanovic, A. A., Gibson, L. E., & Zvolensky, M. J.
- Affiliations
- University of Arkansas at Fayetteville (US)
- University of Vermont (US)
- Venue
- Experimental and Clinical Psychopharmacology
- Published
- 2008-04
- Volume
- 16
- Issue
- 2
- Pages
- 144-155
- ISSN
- 1064-1297 (ISSN-L)
- 1936-2293
- OpenAlex
- W2077565441
- Cited by
- 40
- References
- 63
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 6 · 2014: 4 · 2013: 2 · 2012: 2
- FWCI
- 5.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Experimental and Clinical Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Centers for Disease Control and Prevention (U49 CE001248)
- Arkansas Biosciences Institute
- National Research Service Award (1 F31 DA021006-01)
- National Institute on Drug Abuse (1 R03 DA00101-01, 1 R01 MH076629-01; 1 R01 DA018734-01A1; R03 DA16307-01)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- post-traumatic stress disorder, nicotine withdrawal, hyperventilation, panic symptoms, anxiety, nicotine dependence, mediation, physiological arousal, fear reactivity
- MeSH terms
- Adolescent, Adult, Analysis of Variance, Anxiety, Arousal, Fear, Female, Humans, Hyperventilation, Male, Middle Aged, Smoking, Stress Disorders, Post-Traumatic, Smoking Cessation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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