Cited by 40Posttraumatic Stress Disorder ResearchSmoking Behavior and CessationAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Posttraumatic stress disorder and anxious and fearful reactivity to bodily arousal: A test of the mediating role of nicotine withdrawal severity among daily smokers in 12-hr nicotine deprivation.

Feldner, Matthew T., Vujanovic, Anka A., Gibson, Laura E., Zvolensky, Michael J.·2008·Experimental and Clinical Psychopharmacology

Abstract

Posttraumatic stress disorder (PTSD) is associated with high rates of smoking and fear of bodily perturbation. The current study examined the role of nicotine withdrawal in the association between PTSD and responding to bodily arousal among 52 participants (27 women; M-sub(age) = 30.50 years). Compared to participants without current axis I psychopathology, persons with current PTSD responded to a 3-min voluntary hyperventilation procedure with greater increases in anxiety and more intense cognitive and physical panic symptoms, despite no group differences in physiological arousal. Nicotine withdrawal demonstrated significant mediational effects in the relations between diagnostic group and panic symptoms elicited by the hyperventilation procedure. Findings suggest nicotine withdrawal is an important factor to consider in terms of better understanding the nature of fear responding to bodily sensations among persons with PTSD.

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Crossref · 10.1037/1064-1297.16.2.144

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63 of 63 references verified0 citation errors · 0 not checkable

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  • Nicotine affects dopamine release, providing temporary pleasure and reinforcing the perception that smoking alleviates mental health symptoms, despite actually worsening these symptoms in the long-term.

    “Nicotine affects dopamine release, providing temporary pleasure and reinforcing the perception that smoking alleviates mental health symptoms, despite actually worsening these symptoms in the long-term [12, 13, 14, 15].”

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Authors
Feldner, M. T., Vujanovic, A. A., Gibson, L. E., & Zvolensky, M. J.
Affiliations
  • University of Arkansas at Fayetteville (US)
  • University of Vermont (US)
Venue
Experimental and Clinical Psychopharmacology
Published
2008-04
Volume
16
Issue
2
Pages
144-155
ISSN
  • 1064-1297 (ISSN-L)
  • 1936-2293
OpenAlex
W2077565441
Cited by
40
References
63
Citations by year
2025: 1 · 2024: 2 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 6 · 2014: 4 · 2013: 2 · 2012: 2
FWCI
5.21
Type
journal article
Language
en
Open access
closed
Locations
  • Experimental and Clinical Psychopharmacology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Centers for Disease Control and Prevention (U49 CE001248)
  • Arkansas Biosciences Institute
  • National Research Service Award (1 F31 DA021006-01)
  • National Institute on Drug Abuse (1 R03 DA00101-01, 1 R01 MH076629-01; 1 R01 DA018734-01A1; R03 DA16307-01)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
post-traumatic stress disorder, nicotine withdrawal, hyperventilation, panic symptoms, anxiety, nicotine dependence, mediation, physiological arousal, fear reactivity
MeSH terms
Adolescent, Adult, Analysis of Variance, Anxiety, Arousal, Fear, Female, Humans, Hyperventilation, Male, Middle Aged, Smoking, Stress Disorders, Post-Traumatic, Smoking Cessation

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