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Neuron loss in APP transgenic mice
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“A reduction in the CA1 neuron number of 14% has been demonstrated; however, in this study, both hemi- and homozygous mice with an age of 14 to 18 months were included, which complicates interpretation of the data [41].”
From Neuron Loss in Alzheimer’s Disease: Translation in Transgenic Mouse Models (2020) · cites this paper as [41]
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Metadata
- Authors
- Calhoun, M. E., Wiederhold, K.-H., Abramowski, D., Phinney, A. L., Probst, A., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., & Jucker, M.
- Affiliations
- University of Basel (CH)
- Novartis (Switzerland) (CH)
- Venue
- Nature
- Published
- 1998-10
- Volume
- 395
- Issue
- 6704
- Pages
- 755-756
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1572812739
- Cited by
- 502
- References
- 2
- Citations by year
- 2026: 1 · 2025: 9 · 2024: 9 · 2023: 8 · 2022: 11 · 2021: 10 · 2020: 9 · 2019: 11 · 2018: 10 · 2017: 16 · 2016: 8 · 2015: 20 · 2014: 15 · 2013: 19 · 2012: 21
- FWCI
- 17.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- Alzheimer's disease, amyloid plaques, amyloid precursor protein, APP transgenic mice, neuronal cell death, neurodegeneration, familial Alzheimer's disease
- MeSH terms
- Alzheimer Disease, Animals, Humans, Mice, Transgenic, Mutation, Neurons, Amyloid beta-Protein Precursor, Cell Death, Mice, Plaque, Amyloid
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