A Toll-like receptor recognizes bacterial DNA

Hemmi, Hiroaki, Takeuchi, Osamu, Kawai, Taro, Kaisho, Tsuneyasu, Sato, Shintaro, Sanjo, Hideki, Matsumoto, Makoto, Hoshino, Katsuaki, Wagner, Hermann, Takeda, Kiyoshi, Akira, Shizuo·2000·Nature
DOI 10.1038/35047123

Cited by (1,045)

Items 101–200 of 1,045

  1. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis
    Daniel Rachmilewitz, Kyoko Katakura, Fanny Karmeli, Tomoko Hayashi, Constantin Reinus, Bernard Rudensky, Shizuo Akira, Kiyoshi Takeda, Jong‐Dae Lee, Kenji Takabayashi et al. · 2004 · Gastroenterology
  2. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
    Nobutaka Suzuki, Shinobu Suzuki, Gordon S. Duncan, Douglas G. Millar, Teiji Wada, Christine Mirtsos, Hidetoshi Takada, Andrew C. Wakeham, Annick Itié, Shyun Li et al. · 2002 · Nature
  3. Human lupus autoantibody–DNA complexes activate DCs through cooperation of CD32 and TLR9
    Terry K. Means, Eicke Latz, Fumitaka Hayashi, Mandakolathur R. Murali, Douglas Taylor Golenbock, Andrew David Luster · 2005 · Journal of Clinical Investigation
  4. Pattern Recognition Receptors and the Innate Immune Response to Viral Infection
    Mikayla Thompson, John J. Kaminski, Evelyn A. Kurt‐Jones, Katherine A. Fitzgerald · 2011 · Viruses
  5. Animal Models of sepsis: setting the stage
    Jon A. Buras, Bernhard Holzmann, Michail V. Sitkovsky · 2005 · Nature Reviews Drug Discovery
  6. Hyaluronan in Tissue Injury and Repair
    Jiang, Dianhua, Liang, Jiurong, Noble, Paul W. · 2007 · Annual Review of Cell and Developmental Biology
  7. HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA
    Tara Laurine Roberts, Adi Idris, Jasmyn A. Dunn, Greg Kelly, Carol M. Burnton, Samantha Hodgson, Lani Hardy, Valérie Garceau, Matthew J. Sweet, Ian L. Ross et al. · 2009 · Science
  8. Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
    Züst, Roland, Cervantes-Barragan, Luisa, Habjan, Matthias, Maier, Reinhard, Neuman, Benjamin W, Ziebuhr, John, Szretter, Kristy J, Baker, Susan C, Barchet, Winfried, Diamond, Michael S et al. · 2011 · Nature Immunology
  9. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
    Tiffany Horng, Gregory M. Barton, Richard Anthony Flavell, Ruslan M. Medzhitov · 2002 · Nature
  10. Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells
    Vabulas, Ramunas M., Ahmad-Nejad, Parviz, da Costa, Clarissa, Miethke, Thomas, Kirschning, Carsten J., Häcker, Hans, Wagner, Hermann · 2001 · Journal of Biological Chemistry
  11. Immune surveillance in the skin: mechanisms and clinical consequences
    Thomas Seth Kupper, Robert C. Fuhlbrigge · 2004 · Nature reviews. Immunology
  12. Probiotic bacteria and intestinal epithelial barrier function
    Christina Ohland, Wallace Keith MacNaughton · 2010 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  13. Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
    Tatiana Michel, Jean‐Marc Reichhart, Jules A. Hoffmann, Julien Royet · 2001 · Nature
  14. High IL-13 production by human neonatal T cells: neonate immune system regulator?
    Laura M. Ribeiro-do-Couto, Leonie C.M. Boeije, Jojanneke Kroon, Berend Hooibrink, Birgitta S. Breur-Vriesendorp, Lucien A. Aarden, Claire J. P. Boog · 2001 · European Journal of Immunology
  15. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12
    Anne Krug, Andreas Towarowski, Stefanie Britsch, Simon Rothenfußer, Veit Hornung, Robert Bals, Thomas Giese, Hartmut Engelmann, Stefan Endres, Arthur Μ. Krieg et al. · 2001 · European Journal of Immunology
  16. GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large
    Bruce Beutler, Zhengfan Jiang, Philippe Georgel, Karine Crozat, Ben A. Croker, Sophie Rutschmann, Xin Du, Kasper H. N. Hoebe · 2006 · Annual Review of Immunology
  17. Immune Sensing of DNA
    Søren R. Paludan, Andrew Bowie · 2013 · Immunity
  18. The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
    Mitchell R. McGill, Matthew R. Sharpe, C. David Williams, Mohammad Taha, Steven C. Curry, Hartmut Jaeschke · 2012 · Journal of Clinical Investigation
  19. Receptors, Mediators, and Mechanisms Involved in Bacterial Sepsis and Septic Shock
    Edwin S. van Amersfoort, Theo J.C. van Berkel, Johan Kuiper · 2003 · Clinical Microbiology Reviews
  20. Self-Assembled Multivalent DNA Nanostructures for Noninvasive Intracellular Delivery of Immunostimulatory CpG Oligonucleotides
    Jiang Li, Hao Pei, Bing Zhu, Le Liang, Min Wei, Yao He, Nan Chen, Di Li, Qing Huang, Chunhai Fan · 2011 · ACS Nano
  21. The Plasticity of Dendritic Cell Responses to Pathogens and Their Components
    Qian Huang, Dongyu Liu, Paul Majewski, Leah C. Schulte, Joshua M. Korn, Richard A. Young, Eric S. Lander, Nir Hacohen · 2001 · Science
  22. Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
    Miura, Kouichi, Kodama, Yuzo, Inokuchi, Sayaka, Schnabl, Bernd, Aoyama, Tomonori, Ohnishi, Hirohide, Olefsky, Jerrold M., Brenner, David A., Seki, Ekihiro · 2010 · Gastroenterology
  23. Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    Dipyaman Ganguly, Georgios Chamilos, Roberto Lande, Josh D. Gregorio, Stephan Meller, Valeria Facchinetti, Bernhard Homey, Franck J. Barrat, Tomasz Żal, Michel F. Gilliet · 2009 · The Journal of Experimental Medicine
  24. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
    Tabeta, Koichi, Hoebe, Kasper, Janssen, Edith M, Du, Xin, Georgel, Philippe, Crozat, Karine, Mudd, Suzanne, Mann, Navjiwan, Sovath, Sosathya, Goode, Jason et al. · 2006 · Nature Immunology
  25. Toll-Like Receptors in Antiviral Innate Immunity
    Sandra N. Lester, Kui Li · 2013 · Journal of Molecular Biology
  26. Mitochondria: master regulators of danger signalling
    Galluzzi, Lorenzo, Kepp, Oliver, Kroemer, Guido · 2012 · Nature Reviews Molecular Cell Biology
  27. TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function
    Anne Krug, Anthony R. French, Winfried Barchet, Jens A. A. Fischer, Andrzej Dzionek, Jeanette T. Pingel, Michael M. Orihuela, Shizuo Akira, Wayne M. Yokoyama, Marco Colonna · 2004 · Immunity
  28. Recognition and Signaling by Toll-Like Receptors
    Andrew Phillip West, Anna Alicia Koblansky, Sankar Ghosh · 2006 · Annual Review of Cell and Developmental Biology
  29. Toll‐like receptors and adaptor molecules in liver disease: Update†
    Seki, Ekihiro, Brenner, David A. · 2008 · Hepatology
  30. The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage
    Abu Lila, Amr S., Kiwada, Hiroshi, Ishida, Tatsuhiro · 2013 · Journal of Controlled Release
  31. Bone marrow CD8 T cells are in a different activation state than those in lymphoid periphery
    Francesca Di Rosa, Angela Santoni · 2002 · European Journal of Immunology
  32. Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
    Marcello Chieppa, María Rescigno, Alex Yee-Chen Huang, Ronald N. Germain · 2006 · The Journal of Experimental Medicine
  33. The Interleukin-1 Receptor/Toll-Like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense
    Aisling Dunne, Luke A.J. O'Neill · 2003 · Science Signaling
  34. Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells
    Misako Matsumoto, Kenji Funami, Masako Tanabe, Hiroyuki Oshiumi, Masashi Shingai, Yoshiyuki Seto, Akitsugu Yamamoto, Tsukasa Seya · 2003 · The Journal of Immunology
  35. Innate immunity: the missing link in neuroprotection and neurodegeneration?
    Minh Dang Nguyen, Jean‐Pierre Julien, Serge Rivest · 2002 · Nature reviews. Neuroscience
  36. The Structural Biology of Toll-like Receptors
    Istvan Botos, David M. Segal, David R. Davies · 2011 · Structure
  37. Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9
    Anne Krug, Gary D. Luker, Winfried Barchet, David A. Leib, Shizuo Akira, Marco Colonna · 2003 · Blood
  38. Toll-like Receptor 2 (TLR2) and TLR4 Differentially Activate Human Dendritic Cells
    Fabio Re, Jack L. Strominger · 2001 · Journal of Biological Chemistry
  39. Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8
    Keith B. Gorden, Kevin S. Gorski, Sheila J. Gibson, Ross M. Kedl, William C. Kieper, Xiaohong Qiu, Mark A. Tomai, Şefik Ş. Alkan, John P. Vasilakos · 2005 · The Journal of Immunology
  40. Endogenous ligands of Toll-like receptors
    Min‐Fu Tsan, Baochong Gao · 2004 · Journal of Leukocyte Biology
  41. Toll-like receptors: key mediators of microbe detection
    David M. Underhill, Adrian Ozinsky · 2002 · Current Opinion in Immunology
  42. The evolution and genetics of innate immunity
    D. Kimbrell, B. Beutler · 2001 · Nature reviews genetics
  43. Decreased Expression of Toll-Like Receptor-4 and MD-2 Correlates with Intestinal Epithelial Cell Protection Against Dysregulated Proinflammatory Gene Expression in Response to Bacterial Lipopolysaccharide
    Maria Teresa Abreu, Puja Vora, Emmanuelle Faure, Lisa S. Thomas, Elizabeth T. Arnold, Moshe Arditi · 2001 · The Journal of Immunology
  44. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    Gregory M. Barton, Jonathan C. Kagan, Ruslan M. Medzhitov · 2005 · Nature Immunology
  45. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
    Nadia L. Bernasconi, Nobuyuki Onai, Antonio Lanzavecchia · 2003 · Blood
  46. Early-life programming of later-life brain and behavior: a critical role for the immune system
    Bilbo, Staci D. · 2009 · Frontiers in Behavioral Neuroscience
  47. Staphylococcus aureus Biofilms Prevent Macrophage Phagocytosis and Attenuate Inflammation In Vivo
    Thurlow, Lance R, Hanke, Mark L, Fritz, Teresa, Angle, Amanda, Aldrich, Amy, Williams, Stetson H, Engebretsen, Ian L, Bayles, Kenneth W, Horswill, Alexander R, Kielian, Tammy · 2011 · The Journal of Immunology
  48. siRNA vs. shRNA: Similarities and differences
    Donald D. Rao, John Schoeneman Vorhies, Neil N. Senzer, John J. Nemunaitis · 2009 · Advanced Drug Delivery Reviews
  49. Toll-Like Receptors: Linking Innate and Adaptive Immunity
    Chandrashekhar Pasare, Ruslan M. Medzhitov · 2005 · Advances in experimental medicine and biology
  50. Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
    Xin Li, Chang Shu, Guanghui Yi, Catherine T. Chaton, Catherine L. Shelton, Jiasheng Diao, Xiaobing Zuo, C. Cheng Kao, Andrew B. Herr, Pingwei Li · 2013 · Immunity
  51. Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
    Ramakrishna, Suresh, Kwaku Dad, Abu-Bonsrah, Beloor, Jagadish, Gopalappa, Ramu, Lee, Sang-Kyung, Kim, Hyongbum · 2014 · Genome Research
  52. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
    Ogawa, Sumito, Lozach, Jean, Benner, Chris, Pascual, Gabriel, Tangirala, Rajendra K., Westin, Stefan, Hoffmann, Alexander, Subramaniam, Shankar, David, Michael, Rosenfeld, Michael G. et al. · 2005 · Cell
  53. Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4
    Geoffrey Bates Johnson, Gregory J. Brunn, Yuzo Kodaira, Jeffrey L. Platt · 2002 · The Journal of Immunology
  54. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
    Daniel E. Speiser, Danielle Líénard, Nathalie Rufer, Verena Rubio‐Godoy, Donata Rimoldi, Ferdy J. Lejeune, Arthur Μ. Krieg, Jean‐Charles Cerottini, Pedro J. Romero · 2005 · Journal of Clinical Investigation
  55. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
    Cevayir Coban, Ken J. Ishii, Taro Kawai, Hiroaki Hemmi, Shintaro Sato, Satoshi Uematsu, Masahiro Yamamoto, Osamu Takeuchi, Sawako Itagaki, Nirbhay Kumar et al. · 2005 · The Journal of Experimental Medicine
  56. Human Plasmacytoid Dendritic Cells Activated by CpG Oligodeoxynucleotides Induce the Generation of CD4+CD25+ Regulatory T Cells
    E. Ashley Moseman, Xueqing Liang, Amanda J. Dawson, Angela Panoskaltsis‐Mortari, Arthur Μ. Krieg, Yong‐Jun Liu, Bruce R. Blazar, Wei Chen · 2004 · The Journal of Immunology
  57. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
    Ken J. Ishii, Tatsukata Kawagoe, Shohei Koyama, Kosuke Matsui, Himanshu Kumar, Taro Kawai, Satoshi Uematsu, Osamu Takeuchi, Fumihiko Takeshita, Cevayir Coban et al. · 2008 · Nature
  58. Pathogen-specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells
    Peter McGuirk, Chantelle McCann, Kingston H. G. Mills · 2002 · The Journal of Experimental Medicine
  59. Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
    Avlin B. Imaeda, Azuma Watanabe, Muhammad A. Sohail, Shamail Mahmood, Mehdi Mohamadnejad, Fayyaz Shiraz Sutterwala, Richard Anthony Flavell, Wajahat Zafar Mehal · 2009 · Journal of Clinical Investigation
  60. Dendritic cell lineage, plasticity and cross-regulation
    Yong-Jun Liu, Holger Kanzler, Vassili Soumelis, Michel F. Gilliet · 2001 · Nature Immunology
  61. SIGIRR, a negative regulator of Toll-like receptor–interleukin 1 receptor signaling
    David N. Wald, Jinzhong Qin, Zhendong Zhao, Youcun Qian, Mayumi Naramura, Liping Tian, Jennifer E. Towne, John E. Sims, George Robert Stark, Xiaoxia Li · 2003 · Nature Immunology
  62. DNA nanotechnology from the test tube to the cell
    Chen, Yuan-Jyue, Groves, Benjamin, Muscat, Richard A., Seelig, Georg · 2015 · Nature Nanotechnology
  63. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
    Bafica, Andre, Scanga, Charles A., Feng, Carl G., Leifer, Cynthia, Cheever, Allen, Sher, Alan · 2005 · The Journal of Experimental Medicine
  64. Discriminating self from non-self in nucleic acid sensing
    Martin Schlee, Gunther Hartmann · 2016 · Nature reviews. Immunology
  65. Innate Immunity toMycobacterium tuberculosis
    Reinout van Crevel, Tom H. M. Ottenhoff, Jos W. M. van der Meer · 2002 · Clinical Microbiology Reviews
  66. Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells
    David Pérez-Caballero, Trinity M. Zang, Alaleh Ebrahimi, Matthew W. McNatt, Devon A. Gregory, Marc C. Johnson, Paul D. Bieniasz · 2009 · Cell
  67. TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines
    Min Zheng, Rajendra Karki, Evan Peter Williams, Dong Yang, Elizabeth Ann Fitzpatrick, Peter Vogel, Colleen Beth Jonsson, Thirumala‐Devi Kanneganti · 2021 · Nature Immunology
  68. Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
    Paulos, Chrystal M., Wrzesinski, Claudia, Kaiser,, Andrew, Hinrichs, Christian S., Chieppa, Marcello, Cassard, Lydie, Palmer, Douglas C., Boni, Andrea, Muranski, Pawel, Yu, Zhiya et al. · 2007 · Journal of Clinical Investigation
  69. Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
    Jörg Vollmer, Risini D. Weeratna, Paul Payette, Marion Jurk, Christian Schetter, Meike Laucht, Tanja Wader, Sibylle Tluk, Ming Liu, Heather L. Davis et al. · 2003 · European Journal of Immunology
  70. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7
    Jong‐Dae Lee, Tsung‐Hsien Chuang, Vanessa Redecke, Liping She, Paula M. Pitha, Dennis Anthony Carson, Eyal Raz, Howard Brinkerhoff Cottam · 2003 · Proceedings of the National Academy of Sciences
  71. Toll-like receptors — taking an evolutionary approach
    Leulier, François, Lemaitre, Bruno · 2008 · Nature Reviews Genetics
  72. How we detect microbes and respond to them: the Toll-like receptors and their transducers
    Bruce Beutler, Kasper H. N. Hoebe, XX Du, Richard J. Ulevitch · 2003 · Journal of Leukocyte Biology
  73. Human Coronaviruses: A Review of Virus–Host Interactions
    Yvonne Xinyi Lim, Y. W. Ng, James P. Tam, Ding Xiang Liu · 2016 · Diseases
  74. Pathogen recognition in the innate immune response
    Himanshu Kumar, Taro Kawai, Shizuo Akira · 2009 · Biochemical Journal
  75. Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing
    Glen F. Deleavey, Masad José Damha · 2012 · Chemistry & Biology
  76. A Novel Host-Parasite Lipid Cross-talk
    van der Kleij, Desiree, Latz, Eicke, Brouwers, Jos F.H.M., Kruize, Yvonne C.M., Schmitz, Marion, Kurt-Jones, Evelyn A., Espevik, Terje, de Jong, Esther C., Kapsenberg, Martien L., Golenbock, Douglas T. et al. · 2002 · Journal of Biological Chemistry
  77. Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
    Jörg Vollmer, Arthur Μ. Krieg · 2009 · Advanced Drug Delivery Reviews
  78. Mammalian Toll-like receptors
    Shizuo Akira · 2003 · Current Opinion in Immunology
  79. Characterization of Heme as Activator of Toll-like Receptor 4
    Figueiredo, Rodrigo T., Fernandez, Patricia L., Mourao-Sa, Diego S., Porto, Bárbara N., Dutra, Fabianno F., Alves, Letícia S., Oliveira, Marcus F., Oliveira, Pedro L., Graça-Souza, Aurélio V., Bozza, Marcelo T. · 2007 · Journal of Biological Chemistry
  80. Links between innate and adaptive immunity via type I interferon
    Agnès Le Bon, David F. Tough · 2002 · Current Opinion in Immunology
  81. Nucleic acid recognition by the innate immune system
    Barbalat, Roman, Ewald, Sarah E., Mouchess, Maria L., Barton, Gregory M. · 2011 · Annual Review of Immunology
  82. Klebsiella pneumoniae infection biology: living to counteract host defences
    José Antonio Bengoechea, Joana Sá‐Pessoa · 2018 · FEMS Microbiology Reviews
  83. Quantitative proteomics reveals subset-specific viral recognition in dendritic cells
    Luber, Christian A., Cox, Jürgen, Lauterbach, Henning, Fancke, Ben, Selbach, Matthias, Tschopp, Jurg, Akira, Shizuo, Wiegand, Marian, Hochrein, Hubertus, O'Keeffe, Meredith et al. · 2010 · Immunity
  84. Pathogen recognition with Toll-like receptors
    Taro Kawai, Shizuo Akira · 2005 · Current Opinion in Immunology
  85. Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
    Peggy Parroche, Fanny N. Lauw, Nadège Goutagny, Eicke Latz, Brian G. Monks, Alberto Visintin, Kristen A. Halmen, Marc S. Lamphier, Martin Olivier, Daniella Castanheira Bartholomeu et al. · 2007 · Proceedings of the National Academy of Sciences
  86. The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection
    Hiroaki Hemmi, Osamu Takeuchi, Shintaro Sato, Masahiro Yamamoto, Tsuneyasu Kaisho, Hideki Sanjo, Taro Kawai, Katsuaki Hoshino, Kiyoshi Takeda, Shizuo Akira · 2004 · The Journal of Experimental Medicine
  87. Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex
    Mitsuhiro Fujihara, Masashi Muroi, Ken‐ichi Tanamoto, Tsuneo Suzuki, Hiroshi Azuma, Hisami Ikeda · 2003 · Pharmacology & Therapeutics
  88. Role of Toll-Like Receptors in Pathogen Recognition
    Sophie Janssens, Rudi Beyaert · 2003 · Clinical Microbiology Reviews
  89. The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
    Lionel Apétoh, François Ghiringhelli, Antoine Tesnière, Alfredo Criollo, Carla Ortiz, Rosette Lidereau, C. Mariette, Nathalie Chaput, Jean Paul Mira, Suzette Delaloge et al. · 2007 · Immunological Reviews
  90. Cutting Edge: Role of Toll-Like Receptor 9 in CpG DNA-Induced Activation of Human Cells
    Fumihiko Takeshita, Cynthia Anne Leifer, İhsan Gürsel, Ken J. Ishii, Saoko Takeshita, Mayda Gürsel, Dennis M. Klinman · 2001 · The Journal of Immunology
  91. B cell receptor signal strength determines B cell fate
    Stefano S Casola, Kevin L. Otipoby, Marat B. Alimzhanov, Sibille Humme, Nathalie Uyttersprot, Jeffery Lorne Kutok, Michael C. Carroll, Klaus Rajewsky · 2004 · Nature Immunology
  92. CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery
    Wang, Hong-Xia, Li, Mingqiang, Lee, Ciaran M., Chakraborty, Syandan, Kim, Hae-Won, Bao, Gang, Leong, Kam W. · 2017 · Chemical Reviews
  93. Major findings and recent advances in virus–like particle (VLP)-based vaccines
    Mona Omar Mohsen, Lisha Zha, Gustavo Cabral‐Miranda, Martin F. Bachmann · 2017 · Seminars in Immunology
  94. Toll-like receptors activation, signaling, and targeting: an overview
    Salwa Refat El-Zayat, Hiba Sibaii, Fathia Abd Elwahid Mannaa · 2019 · Bulletin of the National Research Centre/Bulletin of the National Research Center
  95. Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α + DC correlates with unresponsiveness to imidazoquinolines
    Alexander Daniel Edwards, Sandra S. Diebold, Emma Marie Caroline Slack, Hideyuki Tomizawa, Hiroaki Hemmi, Tsuneyasu Kaisho, Shizuo Akira, Caetano Reis e Sousa · 2003 · European Journal of Immunology
  96. Flexibility of Mouse Classical and Plasmacytoid-derived Dendritic Cells in Directing T Helper Type 1 and 2 Cell Development
    André Boonstra, Carine Asselin‐Paturel, Michel F. Gilliet, Chad Crain, Giorgio Trinchieri, Yong-Jun Liu, Anne O’Garra · 2003 · The Journal of Experimental Medicine
  97. Decoding Toll-like receptors: Recent insights and perspectives in innate immunity
    Taro Kawai, Moe Ikegawa, Daisuke Ori, Shizuo Akira · 2024 · Immunity
  98. DNA released from dying host cells mediates aluminum adjuvant activity
    Thomas Marichal, Keiichi Ohata, Denis Bedoret, Claire Mesnil, Catherine M. Sabatel, Kouji Kobiyama, Pierre M. Lekeux, Cevayir Coban, Shizuo Akira, Ken J. Ishii et al. · 2011 · Nature Medicine
  99. The respiratory tract microbiome and lung inflammation: a two-way street.
    Huffnagle, G.B., Dickson, R.P., Lukacs, N.W. · 2017 · Mucosal Immunology
  100. Endogenous toll‐like receptor ligands and their biological significance
    Li Yu, Liantang Wang, Shangwu Chen · 2010 · Journal of Cellular and Molecular Medicine