Toll-like receptors — taking an evolutionary approach

Pathogen Recognition and Innate Immunity

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

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A Toll-like receptor recognizes bacterial DNA

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

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Toll-like receptor control of the adaptive immune responses

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The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

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The host defense of Drosophila melanogaster.

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Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product

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Toll-like receptors in innate immunity

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

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Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway

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Comparative Genomics of the Eukaryotes

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The leucine-rich repeat as a protein recognition motif

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Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

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Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 ( Tlr4 )

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Using FlyAtlas to identify better Drosophila melanogaster models of human disease

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TLR signaling

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Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

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Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins

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Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

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Innate immunity: an overview

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Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

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Toll-like Receptor 9–mediated Recognition of Herpes Simplex Virus-2 by Plasmacytoid Dendritic Cells

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The evolution of vertebrate Toll-like receptors

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TLR3 Deficiency in Patients with Herpes Simplex Encephalitis

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TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein

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Immune pathways and defence mechanisms in honey bees Apis mellifera

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Are innate immune signaling pathways in plants and animals conserved?

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Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

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A Toll-like Receptor That Prevents Infection by Uropathogenic Bacteria

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Immunity-Related Genes and Gene Families in Anopheles gambiae

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The Toll and Imd pathways are the major regulators of the immune response in Drosophila

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A CONSERVED SIGNALING PATHWAY: The <i>Drosophila</i> Toll-Dorsal Pathway

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Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency

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Toll-like receptors in the pathogenesis of human disease

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Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

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GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large

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Herpes Simplex Virus Encephalitis in Human UNC-93B Deficiency

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Cell-Free Immunity in Insects

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Plant NBS-LRR proteins in pathogen sensing and host defense

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Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product

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NLRs join TLRs as innate sensors of pathogens

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Evolutionary Dynamics of Immune-Related Genes and Pathways in Disease-Vector Mosquitoes

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Toll-Like Receptors: Linking Innate and Adaptive Immunity

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Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

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The immune gene repertoire encoded in the purple sea urchin genome

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Toll-like receptors modulate adult hippocampal neurogenesis

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Crystal Structure of Human Toll-Like Receptor 3 (TLR3) Ectodomain

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Cutting Edge: Preferentially the R -Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway

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Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida

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Multigene Analyses of Bilaterian Animals Corroborate the Monophyly of Ecdysozoa, Lophotrochozoa, and Protostomia

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The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling

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The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

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THE EVOLUTION OF ADAPTIVE IMMUNITY

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The new animal phylogeny: Reliability and implications

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Toll‐like receptor 9 binds single‐stranded CpG‐DNA in a sequence‐ and pH‐dependent manner

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TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM

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Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling

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A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling

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A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans.

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Toll-like receptors: linking innate and adaptive immunity

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Genomic Insights into the Immune System of the Sea Urchin

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Toll-related receptors and the control of antimicrobial peptide expression in Drosophila.

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The innate immune repertoire in Cnidaria - ancestral complexity and stochastic gene loss

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The molecular structure of the Toll-like receptor 3 ligand-binding domain

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Cellular Immune Response to Parasite Infection in the Drosophila Lymph Gland Is Developmentally Regulated

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Comparative genomic analysis of the Tribolium immune system

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Structural and functional diversity in the leucine-rich repeat family of proteins

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Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections

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Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: “waiting for Godot”

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Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

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A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis

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COMPARATIVE STUDIES ON THE TOXICITY OF ESCHERICHIA COLI LIPOPOLYSACCHARIDE ENDOTOXIN IN VARIOUS ANIMAL SPECIES

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Dynamic Developmental Elaboration of N-Linked Glycan Complexity in the Drosophila melanogaster Embryo

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Pattern formation. A primer in developmental biology

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Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response

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Dorsoventral Axis Formation in the Drosophila Embryo—Shaping and Transducing a Morphogen Gradient

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Cutting Edge: The Toll Pathway Is Required for Resistance to Gram-Positive Bacterial Infections in Drosophila1

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Toll-Like Receptor 3 Is a Potent Negative Regulator of Axonal Growth in Mammals

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Endotoxin recognition: In fish or not in fish?

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Toll-like receptors on regulatory T cells: expanding immune regulation

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A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signalingPreprint

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A conserved Toll‐like receptor is required for Caenorhabditis elegans innate immunity

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